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    SEC Form SC 13D/A filed by Eliem Therapeutics Inc (Amendment)

    6/6/24 4:16:11 PM ET
    $ELYM
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $ELYM alert in real time by email
    SC 13D/A 1 tm2416616d1_sc13da.htm SC 13D/A

     

     

    UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
     

    Washington, D.C. 20549  

     

    SCHEDULE 13D

     

    Under the Securities Exchange Act of 1934
    (Amendment No. 6)*

     

    Eliem Therapeutics, Inc.

    (Name of Issuer)

     

    Common Stock, par value $0.0001 per share

    (Title of Class of Securities)

     

    28658R 106

    (CUSIP Number)

     

    RA Capital Management, L.P.

    200 Berkeley Street, 18th Floor

    Boston, MA 02116

    Attn: Peter Kolchinsky

    Telephone: 617.778.2500

    (Name, Address and Telephone Number of Person
    Authorized to Receive Notices and Communications)

     

    June 4, 2024

    (Date of Event Which Requires Filing of this Statement)

     

    If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. ¨

     

    Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Section 240.13d-7 for other parties to whom copies are to be sent.

     

    * The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

     

    The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934, as amended (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

     

     

     

     

     

    CUSIP No. 28658R 106

     

      1.

    Names of Reporting Persons.

    RA Capital Management, L.P.

     
      2. Check the Appropriate Box if a Member of a Group (See Instructions)
        (a)  ¨
        (b)  ¨
     
      3. SEC Use Only
     
      4. Source of Funds (See Instructions)
    AF
     
      5. Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)     ¨
     
      6. Citizenship or Place of Organization
    Delaware
     

    Number of
    Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    7. Sole Voting Power
    0
     
    8. Shared Voting Power
    13,190,849
     
    9. Sole Dispositive Power
    0
     
    10. Shared Dispositive Power
    13,190,849
     

      11. Aggregate Amount Beneficially Owned by Each Reporting Person
    13,190,849
     
      12. Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions)   ¨
     
      13. Percent of Class Represented by Amount in Row (11)
    44.3%
     
      14. Type of Reporting Person (See Instructions)
    IA, PN

     

     

     

     

    CUSIP No. 28658R 106

     

      1.

    Names of Reporting Persons.

    Peter Kolchinsky

     
      2. Check the Appropriate Box if a Member of a Group (See Instructions)
        (a)  ¨
        (b)  ¨
     
      3. SEC Use Only
     
      4. Source of Funds (See Instructions)
    AF
     
      5. Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)     ¨
     
      6. Citizenship or Place of Organization
    United States
     

    Number of
    Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    7. Sole Voting Power
    0
     
    8. Shared Voting Power
    13,190,849
     
    9. Sole Dispositive Power
    0
     
    10. Shared Dispositive Power
    13,190,849
     

      11. Aggregate Amount Beneficially Owned by Each Reporting Person
    13,190,849
     
      12. Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions)   ¨
     
      13. Percent of Class Represented by Amount in Row (11)
    44.3%
     
      14. Type of Reporting Person (See Instructions)
    HC, IN

     

     

     

     

    CUSIP No. 28658R 106

     

      1.

    Names of Reporting Persons.

    Rajeev Shah

     
      2. Check the Appropriate Box if a Member of a Group (See Instructions)
        (a)  ¨
        (b)  ¨
     
      3. SEC Use Only
     
      4. Source of Funds (See Instructions)
    AF
     
      5. Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)     ¨
     
      6. Citizenship or Place of Organization
    United States
     

    Number of
    Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    7. Sole Voting Power
    0
     
    8. Shared Voting Power
    13,190,849
     
    9. Sole Dispositive Power
    0
     
    10. Shared Dispositive Power
    13,190,849
     

      11. Aggregate Amount Beneficially Owned by Each Reporting Person
    13,190,849
     
      12. Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions)   ¨
     
      13. Percent of Class Represented by Amount in Row (11)
    44.3%
     
      14. Type of Reporting Person (See Instructions)
    HC, IN

     

     

     

     

    CUSIP No. 28658R 106

     

      1.

    Names of Reporting Persons.

    RA Capital Healthcare Fund, L.P.

     
      2. Check the Appropriate Box if a Member of a Group (See Instructions)
        (a)  o
        (b)  o
     
      3. SEC Use Only
     
      4. Source of Funds (See Instructions)
    WC
     
      5. Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)     o
     
      6. Citizenship or Place of Organization
    Delaware
     

    Number of
    Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    7. Sole Voting Power
    0
     
    8. Shared Voting Power
    10,599,586
     
    9. Sole Dispositive Power
    0
     
    10. Shared Dispositive Power
    10,599,586
     

      11. Aggregate Amount Beneficially Owned by Each Reporting Person
    10,599,586
     
      12. Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions)   o
     
      13. Percent of Class Represented by Amount in Row (11)
    35.6%
     
      14. Type of Reporting Person (See Instructions)
    PN

     

     

     

     

    CUSIP No. 28658R 106

     

    Item 1.Security and Issuer

     

    Item 1 of the Statement is amended and supplemented as follows:

     

    This Amendment No. 6 (this “Amendment No. 6” or this “Schedule 13D/A”) amends and supplements the statement on the Schedule 13D originally filed with the Securities and Exchange Commission (the “SEC”) on August 19, 2021, and amended on April 10, 2023, November 17, 2023, March 18, 2024, April 12, 2024 and May 17, 2024 (as amended, the “Statement”), filed by RA Capital Management, L.P., Dr. Kolchinsky, Mr. Shah, and RA Capital Healthcare Fund, L.P. with respect to the common stock, par value $0.0001 per share (the “Common Stock”), of Eliem Therapeutics, Inc., a Delaware corporation (the “Issuer”). Unless otherwise defined herein, capitalized terms used in this Amendment No. 6 shall have the meanings ascribed to them in the Statement. Unless amended or supplemented below, the information in the Statement remains unchanged.

     

    Item 2.Identity and Background

     

    Item 2 of the Statement is hereby amended and restated as follows:

     

    (a)This Schedule 13D/A is being filed on behalf of RA Capital Management, L.P. (“RA Capital”), Peter Kolchinsky, Rajeev Shah, and RA Capital Healthcare Fund, L.P. (the “Fund”). RA Capital, Dr. Kolchinsky, Mr. Shah and the Fund are collectively referred to herein as the “Reporting Persons.”

     

    The Reporting Persons’ beneficial ownership of the Issuer’s securities includes (i) 10,599,586 shares of Common Stock held directly by the Fund, (ii) 1,226,497 shares of Common Stock held directly by RA Capital Nexus Fund, L.P (the “Nexus Fund”), (iii) 483,679 shares of Common Stock held directly by RA Capital Nexus Fund II, L.P. (the “Nexus Fund II”), (iv) 841,087 shares of Common Stock held directly by a separately managed account (the “Account”), (v) a total of 38,888 vested stock options (right to buy), and (vi) 1,112 stock options (right to buy) which shall vest within 60 days of this filing.

     

    RA Capital Healthcare Fund GP, LLC is the general partner of the Fund, RA Capital Nexus Fund GP, LLC is the general partner of the Nexus Fund, and RA Capital Nexus Fund II GP, LLC is the general partner of the Nexus Fund II. The general partner of RA Capital is RA Capital Management GP, LLC, of which Dr. Kolchinsky and Mr. Shah are the controlling persons. RA Capital serves as investment adviser for the Fund, the Nexus Fund, the Nexus Fund II, and the Account and may be deemed a beneficial owner, for purposes of Section 13(d) of the Securities Exchange Act of 1934 (the “Act”), of any securities of the Issuer held by the Fund, the Nexus Fund, the Nexus Fund II or the Account. The Fund, the Nexus Fund, and the Nexus Fund II have delegated to RA Capital the sole power to vote and the sole power to dispose of all securities held in the Fund, the Nexus Fund, and the Nexus Fund II, and each of these funds has divested themselves of voting and investment power over the reported securities they hold and may not revoke that delegation on less than 61 days’ notice. The Fund, the Nexus Fund, and the Nexus Fund II disclaim beneficial ownership of the securities they hold for purposes of Section 13(d) of the Act and therefore disclaim any obligation to report ownership of the reported securities under Section 13(d) of the Act. As managers of RA Capital, Dr. Kolchinsky and Mr. Shah may be deemed beneficial owners, for purposes of Section 13(d) of the Act, of any securities of the Issuer beneficially owned by RA Capital. RA Capital, Dr. Kolchinsky, and Mr. Shah disclaim beneficial ownership of the securities reported in this Schedule 13D/A other than for the purpose of determining their obligations under Section 13(d) of the Act, and the filing of the Schedule 13D/A shall not be deemed an admission that either RA Capital, Dr. Kolchinsky, or Mr. Shah is the beneficial owner of such securities for any other purpose.

     

    (b)The address of the principal business office of each of the Reporting Persons is 200 Berkeley Street, 18th Floor, Boston, MA 02116.

     

    (c)The Fund is a private investment vehicle. RA Capital provides investment management services to the Fund, the Nexus Fund, the Nexus Fund II, and the Account. The principal occupation of Dr. Kolchinsky and Mr. Shah is investment management.

     

    (d)During the last five years, none of the Reporting Persons has been convicted in a criminal proceeding (excluding traffic violations or similar misdemeanors).

     

    (e)During the last five years, none of the Reporting Persons has been a party to a civil proceeding of a judicial or administrative body of competent jurisdiction and as a result of such proceeding was or is subject to a judgment, decree of final order enjoining future violations of, or prohibiting or mandating activities subject to, federal or state securities laws or finding any violation with respect to such laws.

     

    (f)See Item 6 of the cover pages.

     

     

     

     

    CUSIP No. 28658R 106

     

    Item 5.Interest in Securities of the Issuer

     

    Item 5 of the Statement is hereby amended and restated in its entirety to read as follows:

     

    (a)The information set forth in rows 11 and 13 of the cover pages to this Schedule 13D/A is incorporated by reference. The percentage set forth in row 13 is based on the sum of (i) 29,752,317 shares of Common Stock outstanding as of May 30, 2024, as reported in the Issuer’s Proxy Statement on Schedule 14A filed with the SEC on June 4, 2024 and (ii) 40,000 shares of Common Stock issuable upon the exercise of stock options within 60 days.

     

    (b)The information set forth in rows 7 through 10 of the cover pages to this Schedule 13D/A and Item 2 above is incorporated by reference.

     

    (c)Schedule A sets forth all transactions with respect to the shares of Common Stock effected since the most recent amendment to this Statement by any Reporting Person and is incorporated herein by reference.

     

    (d)No person (other than the Reporting Persons) is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, the shares of Common Stock subject to this Schedule 13D/A.

     

    (e)Not applicable.

     

    Item 7.Material to be Filed as Exhibits

     

    Item 7 of the Statement is hereby amended and supplemented as follows:

     

    Exhibit 1Joint Filing Agreement

     

     

     

     

    CUSIP No. 28658R 106

     

    SIGNATURES

     

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     

    Dated: June 6, 2024

     

    RA CAPITAL MANAGEMENT, L.P.  
         
    By: /s/ Peter Kolchinsky  
      Name: Peter Kolchinsky  
      Title: Authorized Signatory  

     

    PETER KOLCHINSKY  
       
    /s/ Peter Kolchinsky  
       
    RAJEEV SHAH  
       
    /s/ Rajeev Shah  

     

    RA CAPITAL HEALTHCARE FUND, L.P.  
         
    By: RA Capital Healthcare Fund GP, LLC  
    Its: General Partner  

      

    By: /s/ Peter Kolchinsky  
      Name: Peter Kolchinsky  
      Title: Manager  

     

     

     

     

    CUSIP No. 28658R 106

     

    SCHEDULE A†

     

    Transaction  Purchaser  Date  No. Shares   Price 
    Vest Stock Option (Right to Buy)  RA Capital  08/01/2024   557    (1)*

     

    (1)This option represents a right to purchase a total of 20,000 shares of the Issuer's Common Stock, which began vesting on August 1, 2021 in 36 equal monthly installments over three years, subject to Dr. Levin’s continued service to the Issuer through each vesting date. These options have an exercise price of $12.50.

     

    * Represents future vesting options within 60 days from the filing date of this Schedule 13D/A.

     

     

    †The Common Stock and percentage ownership reported in this amendment reflect an increase in the number of outstanding shares of the Issuer. The vesting options in Schedule A did not cause a material change in the Reporting Persons’ beneficial ownership.

     

     

     

     

    CUSIP No. 28658R 106

     

    EXHIBIT 1

     

    JOINT FILING AGREEMENT

     

    This Joint Filing Agreement, dated as of June 6, 2024, is by and among RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, and RA Capital Healthcare Fund, L.P. (the foregoing are collectively referred to herein as the “Filers”).

     

    Each of the Filers may be required to file with the United States Securities and Exchange Commission a statement on Schedule 13G and/or 13D with respect to Common Stock, par value $0.0001 per share of Eliem Therapeutics, Inc. beneficially owned by them from time to time.

     

    Pursuant to and in accordance with Rule 13(d)(1)(k) promulgated under the Securities Exchange Act of 1934, as amended, the Filers hereby agree to file a single statement on Schedule 13G and/or 13D (and any amendments thereto) on behalf of each of such parties, and hereby further agree to file this Joint Filing Agreement as an exhibit to such statement, as required by such rule.

     

    This Joint Filing Agreement may be terminated by any of the Filers upon one week’s prior written notice or such lesser period of notice as the Filers may mutually agree.

     

    Executed and delivered as of the date first above written.

     

    RA CAPITAL MANAGEMENT, L.P.  
         
    By: /s/ Peter Kolchinsky  
      Name: Peter Kolchinsky  
      Title: Authorized Signatory  

     

    PETER KOLCHINSKY  
       
    /s/ Peter Kolchinsky  
       
    RAJEEV SHAH  
       
    /s/ Rajeev Shah  

     

    RA CAPITAL HEALTHCARE FUND, L.P.  
         
    By: RA Capital Healthcare Fund GP, LLC  
    Its: General Partner  

      

    By: /s/ Peter Kolchinsky  
      Name: Peter Kolchinsky  
      Title: Manager  

     

     

     

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      SEATTLE and CAMBRIDGE, United Kingdom, Sept. 11, 2024 (GLOBE NEWSWIRE) -- Eliem Therapeutics, Inc. (NASDAQ:ELYM), announced today members of the management team will participate at the Stifel 2024 Virtual Immunology and Inflammation Summit being held September 17-18, 2024. Stifel 2024 Virtual Immunology and Inflammation SummitDate: Wednesday, September 18, 2024Format: 1x1 meetings About Eliem Therapeutics, Inc.Eliem Therapeutics is focused on developing therapeutics for autoimmune-driven inflammatory diseases, including advancing budoprutug, an anti-CD19 antibody designed for a broad range of autoimmune diseases, including systemic lupus erythematosus, lupus nephritis, immune thrombocyto

      9/11/24 7:00:00 AM ET
      $ELYM
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Eliem Therapeutics Announces Additions to its Leadership Team

      Brett Kaplan, M.D. appointed Chief Operating Officer Nishi Rampal, M.D. appointed Senior Vice President, Clinical Development SEATTLE and CAMBRIDGE, United Kingdom, Aug. 26, 2024 (GLOBE NEWSWIRE) -- Eliem Therapeutics, Inc. (NASDAQ:ELYM), announced today the appointments of Brett Kaplan, M.D., as Chief Operating Officer, and Nishi Rampal, M.D., as Senior Vice President, Clinical Development. "I am delighted to announce the addition of Brett and Nishi to our executive team," said Dr. Aoife Brennan, CEO of Eliem Therapeutics. "Since completing the Tenet Medicines acquisition, we have worked diligently to build a best-in-class management team as we transition Eliem into a leading bio

      8/26/24 7:00:00 AM ET
      $ELYM
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $ELYM
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    • Guggenheim initiated coverage on Eliem Therapeutics with a new price target

      Guggenheim initiated coverage of Eliem Therapeutics with a rating of Buy and set a new price target of $32.00

      9/7/21 7:18:57 AM ET
      $ELYM
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Stifel initiated coverage on Eliem Therapeutics with a new price target

      Stifel initiated coverage of Eliem Therapeutics with a rating of Buy and set a new price target of $35.00

      9/7/21 7:17:07 AM ET
      $ELYM
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SVB Leerink initiated coverage on Eliem Therapeutics with a new price target

      SVB Leerink initiated coverage of Eliem Therapeutics with a rating of Outperform and set a new price target of $33.00

      9/7/21 6:28:45 AM ET
      $ELYM
      Biotechnology: Pharmaceutical Preparations
      Health Care