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    SEC Form SC 13D/A filed by Graybug Vision Inc. (Amendment)

    5/23/23 5:25:16 PM ET
    $GRAY
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $GRAY alert in real time by email
    SC 13D/A 1 e618664_sc13da-calcimedica.htm

     

    SECURITIES AND EXCHANGE COMMISSION

    Washington, D.C. 20549

     

    SCHEDULE 13D

     

    [Rule 13d-101]

     

    INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 24.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13D-2(a)

     

    (Amendment No. 5)*

     

    CalciMedica, Inc.

    (Name of Issuer)

     

    Common Stock, par value $0.0001 per share

    (Title of Class of Securities)

     

    38942Q202

    (CUSIP Number)

     

    David Clark

    Elliot Press

    Deerfield Management Company, L.P.

    345 Park Avenue South, 12th Floor

    New York, New York 10010

    (212) 551-1600

     

    With a copy to:

     

    Jonathan D. Weiner, Esq.

    Mark D. Wood, Esq.

    Katten Muchin Rosenman LLP

    50 Rockefeller Plaza

    New York, New York 10020

    (212) 940-8800

     

    (Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)

     

    May 19, 2023

    (Date of Event which Requires Filing of this Statement)

     

    If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box ☐.

     

    Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See § 240.13d-7 for other parties to whom copies are to be sent.

     

    (Continued on following pages)
    (Page 1 of 13 Pages)

     

    * The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

     

    The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

     

     

      

     

    SCHEDULE 13D

     

    CUSIP No.  38942Q202 Page 2 of 13 Pages

     

    1

    NAME OF REPORTING PERSONS

     

    Deerfield Mgmt III, L.P.

     
    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

      

    (a) ☐

    (b) ☒

     

    3

    SEC USE ONLY

     

     

     
    4

    SOURCE OF FUNDS

     

    AF

     
    5

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

    ☐
    6

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

     

     NUMBER OF 

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

    7

    SOLE VOTING POWER

     

    0

     
    8

    SHARED VOTING POWER

     

    122,419 (1)

     

    9

     

    SOLE DISPOSITIVE POWER

     

    0

     

    10

     

    SHARED DISPOSITIVE POWER

     

    122,419 (1)

     

    11

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    122,419 (1)

     
    12

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* 

     

    ☐ 

    13

     

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

    2.16%

     
    14

    TYPE OF REPORTING PERSON

     

    PN

     

     

    (1) Comprised of 122,419 shares of common stock held by Deerfield Private Design Fund III, L.P.

       

     

      

     

    SCHEDULE 13D

     

    CUSIP No.  38942Q202 Page 3 of 13 Pages

     

    1

    NAME OF REPORTING PERSONS

     

    Deerfield Private Design Fund III, L.P.

     
    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

     

     

    (a) ☐

    (b) ☒

     

    3

    SEC USE ONLY

     

     

     
    4

    SOURCE OF FUNDS

     

    WC

     
    5

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

    ☐
    6

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

     

     NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

    7

    SOLE VOTING POWER

     

    0

     
    8

    SHARED VOTING POWER

     

    122,419

     

    9

     

    SOLE DISPOSITIVE POWER

     

    0

     

    10

     

    SHARED DISPOSITIVE POWER

     

    122,419

     

    11

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    122,419

     
    12

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*

     

    ☐ 

    13

     

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

    2.16%

     
    14

    TYPE OF REPORTING PERSON

     

    PN

     

     

     

      

     

    SCHEDULE 13D

     

    CUSIP No.  38942Q202 Page 4 of 13 Pages

     

    1

    NAME OF REPORTING PERSONS

     

    Deerfield Mgmt HIF, L.P.

     
    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

     

     

    (a) ☐

    (b) ☒

     

    3

    SEC USE ONLY

     

     

     
    4

    SOURCE OF FUNDS

     

    AF

     
    5

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

    ☐
    6

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

     

     NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

    7

    SOLE VOTING POWER

     

    0

     
    8

    SHARED VOTING POWER

     

    122,419 (2)

     

    9

     

    SOLE DISPOSITIVE POWER

     

    0

     

    10

     

    SHARED DISPOSITIVE POWER

     

    122,419 (2)

     

    11

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    122,419 (2)

     
    12

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*

     

    ☐ 

    13

     

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

    2.16%

     
    14

    TYPE OF REPORTING PERSON

     

    PN

     

     

    (2) Comprised of 122,419 shares of common stock held by Deerfield Healthcare Innovations Fund, L.P.

     

     

      

     

    SCHEDULE 13D

     

    CUSIP No.  38942Q202 Page 5 of 13 Pages

     

    1

    NAME OF REPORTING PERSONS

     

    Deerfield Healthcare Innovations Fund, L.P.

     
    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

     

     

    (a) ☐

    (b) ☒

     

    3

    SEC USE ONLY

     

     

     
    4

    SOURCE OF FUNDS

     

    WC

     
    5

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

    ☐
    6

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

     

     NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

    7

    SOLE VOTING POWER

     

    0

     
    8

    SHARED VOTING POWER

     

    122,419

     

    9

     

    SOLE DISPOSITIVE POWER

     

    0

     

    10

     

    SHARED DISPOSITIVE POWER

     

    122,419

     

    11

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    122,419

     
    12

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*

     

    ☐ 

    13

     

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

    2.16%

     
    14

    TYPE OF REPORTING PERSON

     

    PN

     

      

     

      

     

    SCHEDULE 13D

     

    CUSIP No.  38942Q202 Page 6 of 13 Pages

     

    1

    NAME OF REPORTING PERSONS

     

    Deerfield Mgmt, L.P.

     
    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

     

     

    (a) ☐

    (b) ☒

     

    3

    SEC USE ONLY

     

     

     
    4

    SOURCE OF FUNDS

     

    AF

     
    5

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

    ☐
    6

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

     

     NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

    7

    SOLE VOTING POWER

     

    0

     
    8

    SHARED VOTING POWER

     

    31,960 (3)

     

    9

     

    SOLE DISPOSITIVE POWER

     

    0

     

    10

     

    SHARED DISPOSITIVE POWER

     

    31,960 (3)

     

    11

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    31,960 (3)

     
    12

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*

     

    ☐ 

    13

     

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

    0.56%

     
    14

    TYPE OF REPORTING PERSON

     

    PN

     

     

    (3) Comprised of 31,960 shares of common stock held by Deerfield Partners, L.P.

       

     

      

    SCHEDULE 13D

    CUSIP No.  38942Q202 Page 7 of 13 Pages

     

    1

    NAME OF REPORTING PERSONS

     

    Deerfield Partners, L.P.

     
    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

     

     

    (a) ☐

    (b) ☒

     

    3

    SEC USE ONLY

     

     

     
    4

    SOURCE OF FUNDS

     

    WC

     
    5

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

    ☐
    6

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

     

     NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

    7

    SOLE VOTING POWER

     

    0

     
    8

    SHARED VOTING POWER

     

    31,960

     

    9

     

    SOLE DISPOSITIVE POWER

     

    0

     

    10

     

    SHARED DISPOSITIVE POWER

     

    31,960

     

    11

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    31,960

     
    12

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*

     

    ☐ 

    13

     

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

    0.56%

     
    14

    TYPE OF REPORTING PERSON

     

    PN

     

     

     

      

    SCHEDULE 13D

    CUSIP No.  38942Q202 Page 8 of 13 Pages

     

    1

    NAME OF REPORTING PERSONS

     

    Deerfield Management Company, L.P.

     
    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

     

     

    (a) ☐

    (b) ☒

     

    3

    SEC USE ONLY

     

     

     
    4

    SOURCE OF FUNDS

     

    AF

     
    5

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

     

    ☒
    6

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

     

     NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

    7

    SOLE VOTING POWER

     

    0

     
    8

    SHARED VOTING POWER

     

    276,798 (4)

     

    9

     

    SOLE DISPOSITIVE POWER

     

    0

     

    10

     

    SHARED DISPOSITIVE POWER

     

    276,798 (4)

     

    11

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    276,798 (4)

     
    12

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*

     

     

    ☐ 

    13

     

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

    4.89%

     
    14

    TYPE OF REPORTING PERSON

     

    PN

     

     

    (4) Comprised of an aggregate of 276,798 shares of common stock held by Deerfield Partners, L.P., Deerfield Healthcare Innovations Fund, L.P. and Deerfield Private Design Fund III, L.P.

           

     

      

    SCHEDULE 13D

    CUSIP No.  38942Q202 Page 9 of 13 Pages

     

    1

    NAME OF REPORTING PERSONS

     

    James E. Flynn

     
    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

     

     

    (a) ☐

    (b) ☒

     

    3

    SEC USE ONLY

     

     

     
    4

    SOURCE OF FUNDS

     

    AF

     
    5

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

     

    ☐
    6

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    United States of America

     

     

     

     NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

    7

    SOLE VOTING POWER

     

    0

     
    8

    SHARED VOTING POWER

     

    276,798 (6)

     

    9

     

    SOLE DISPOSITIVE POWER

     

    0

     

    10

     

    SHARED DISPOSITIVE POWER

     

    276,798 (6)

     

    11

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    276,798 (6)

     
    12

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*

     

     

    ☐ 

    13

     

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

    4.89%

     
    14

    TYPE OF REPORTING PERSON*

     

    IN

     

     

    (6) Comprised of an aggregate of 276,798 shares of common stock held by Deerfield Partners, L.P., Deerfield Healthcare Innovations Fund, L.P. and Deerfield Private Design Fund III, L.P.

         

     

      

    SCHEDULE 13D

    CUSIP No.  38942Q202 Page 10 of 13 Pages

     

    This Amendment No. 5 (this “Amendment”) to Schedule 13D amends the Schedule 13D filed by (i) Deerfield Mgmt III, L.P. (“Deerfield Mgmt III”), (ii) Deerfield Private Design Fund III, L.P. (“Deerfield Private Design Fund III”), (iii) Deerfield Mgmt, L.P. (“Deerfield Mgmt”), (iv) Deerfield Partners, L.P. (“Deerfield Partners”), (v) Deerfield Mgmt HIF, L.P. (“Deerfield Mgmt HIF”), (vi) Deerfield Healthcare Innovations Fund, L.P. (“Deerfield Healthcare Innovations Fund”), (vii) Deerfield Management Company, L.P. (“Deerfield Management”) and (viii) James E. Flynn, a natural person (“Flynn” and collectively with Deerfield Mgmt III, Deerfield Private Design Fund III, Deerfield Mgmt, Deerfield Partners, Deerfield Mgmt HIF, Deerfield Healthcare Innovations Fund and Deerfield Management, the “Reporting Persons”), as amended by Amendment No. 1, Amendment No. 2, Amendment No. 3 and Amendment No. 4 thereto (the “Schedule 13D”), with respect to the common stock of CalciMedica, Inc. (the “Company”). Deerfield Private Design Fund III, Deerfield Healthcare Innovations Fund and Deerfield Partners are collectively referred to herein as the “Funds”.

     

    Capitalized terms used but not otherwise defined in this Amendment have the meanings ascribed to them in the Schedule 13D.

     

    Item 5. Interest in Securities of the Issuer.

     

    Items 5(a), (b), (c) and (e) of the Schedule 13D are hereby amended and restated in their entirety as follows:

     

    (a)      
           
      (1) Deerfield Mgmt III  
           
        Number of shares:   122,419 (comprised of shares held by Deerfield Private Design Fund III)
        Percentage of shares: 2.16%
           
      (2)   Deerfield Private Design Fund III
           
        Number of shares:   122,419
        Percentage of shares: 2.16%
           
      (3)   Deerfield Mgmt  
           
        Number of shares:   31,960 (comprised of shares held by Deerfield Partners)
        Percentage of shares: 0.56%
           
      (4) Deerfield Partners  
           
        Number of shares:   31,960
        Percentage of shares: 0.56%
           
      (5) Deerfield Mgmt HIF  
           
        Number of shares:   122,419 (comprised of shares held by Deerfield Healthcare Innovations Fund)
        Percentage of shares: 2.16%

     

     

     

     

    SCHEDULE 13D

    CUSIP No.  38942Q202 Page 11 of 13 Pages

      

           
      (6) Deerfield Healthcare Innovations Fund
           
        Number of shares:   122,419
        Percentage of shares: 2.16%
           
      (7) Deerfield Management  
           
        Number of shares:   276,798 (comprised of shares held by Deerfield Private Design Fund III, Deerfield Healthcare Innovations Fund and Deerfield Partners)
        Percentage of shares: 4.89%
           
      (8) Flynn  
           
        Number of shares:   276,798 (comprised of shares held by Deerfield Private Design Fund III, Deerfield Healthcare Innovations Fund and Deerfield Partners)
        Percentage of shares: 4.89%

     

    *Percentage beneficial ownership reported herein reflects 5,661,933 shares of Common Stock outstanding, as disclosed in the Company’s Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2023.

     

    (b)    
         
      (1) Deerfield Mgmt III
         
        Sole power to vote or direct the vote:  0
        Shared power to vote or direct the vote:   122,419
        Sole power to dispose or to direct the disposition:  0
        Shared power to dispose or direct the disposition:   122,419
         
      (2) Deerfield Private Design Fund III
         
        Sole power to vote or direct the vote:  0
        Shared power to vote or direct the vote:  122,419
        Sole power to dispose or to direct the disposition:  0
        Shared power to dispose or direct the disposition:  122,419
         
      (3) Deerfield Mgmt HIF
         
        Sole power to vote or direct the vote:  0
        Shared power to vote or direct the vote:   122,419
        Sole power to dispose or to direct the disposition:  0
        Shared power to dispose or direct the disposition:   122,419
         
      (4) Deerfield Healthcare Innovations Fund
        Sole power to vote or direct the vote:  0
        Shared power to vote or direct the vote:   122,419
        Sole power to dispose or to direct the disposition:  0
        Shared power to dispose or direct the disposition:   122,419

      

     

     

     

    SCHEDULE 13D

    CUSIP No.  38942Q202 Page 12 of 13 Pages

      

     

         
      (5)  Deerfield Mgmt
         
        Sole power to vote or direct the vote:  0
        Shared power to vote or direct the vote:  31,960
        Sole power to dispose or to direct the disposition:  0
        Shared power to dispose or direct the disposition:  31,960
         
      (6) Deerfield Partners
         
        Sole power to vote or direct the vote:  0
        Shared power to vote or direct the vote:  31,960
        Sole power to dispose or to direct the disposition:  0
        Shared power to dispose or direct the disposition:  31,960
         
      (7) Deerfield Management
         
        Sole power to vote or direct the vote:  0
        Shared power to vote or direct the vote:  276,798
        Sole power to dispose or to direct the disposition:  0
        Shared power to dispose or direct the disposition:  276,798
         
      (8) Flynn
         
        Sole power to vote or direct the vote:  0
        Shared power to vote or direct the vote:  276,798
        Sole power to dispose or to direct the disposition:  0
        Shared power to dispose or direct the disposition:  276,798

      

    Flynn is the managing member of the general partner of each of Deerfield Mgmt, Deerfield Mgmt III, Deerfield Mgmt HIF and Deerfield Management.  Deerfield Mgmt III is the general partner of Deerfield Private Design Fund III; Deerfield Mgmt HIF is the general partner of Deerfield Healthcare Innovations Fund and Deerfield Mgmt is the general partner of Deerfield Partners. Deerfield Management is the investment manager of the Funds.

     

    (c) Transactions in the common stock effected by the Reporting Persons in the last sixty (60) days are set forth on Schedule A to this Amendment. All transactions reflected in Schedule A to this Amendment were effected in open market transactions in the over-the-counter market in the ordinary course of the applicable Reporting Person’s business.

     

    (e) As of May 23, 2023, the Reporting Persons ceased to beneficially own more than five percent of the Common Stock.

     

     

     

     

    SCHEDULE 13D

    CUSIP No.  38942Q202 Page 13 of 13 Pages

      

    SIGNATURE

     

    After reasonable inquiry and to the best of their knowledge and belief, the undersigned certify that the information set forth in this statement is true, complete and correct.

     
    Dated: May 23, 2023

     

      DEERFIELD MGMT III, L.P.
      By: J.E. Flynn Capital III, LLC, General Partner
         
      By:    /s/ Jonathan Isler
      Name:   Jonathan Isler   
      Title:   Attorney-in-Fact    
         
         
      DEERFIELD PRIVATE DESIGN FUND III, L.P.
      By: Deerfield Mgmt III, L.P., General Partner
      By: J.E. Flynn Capital III, LLC, General Partner
         
      By:    /s/ Jonathan Isler
      Name:   Jonathan Isler   
      Title:   Attorney-in-Fact    
         
         
      DEERFIELD MGMT HIF, L.P.
      By:  J.E. Flynn Capital HIF, LLC, General Partner
         
      By:   /s/ Jonathan Isler
               Jonathan Isler, Attorney-In-Fact
         
         
      DEERFIELD HEALTHCARE INNOVATIONS FUND, L.P.
      By:  Deerfield Mgmt HIF, L.P., General Partner
      By:  J.E. Flynn Capital HIF, LLC, General Partner
         
      By:   /s/ Jonathan Isler
      Jonathan Isler, Attorney-In-Fact
         
         
      DEERFIELD PARTNERS, L.P.
      By:  Deerfield Mgmt, L.P., General Partner
      By:  J.E. Flynn Capital, LLC, General Partner
         
      By:    /s/ Jonathan Isler
      Name:   Jonathan Isler   
      Title:   Attorney-in-Fact    
         
         
      DEERFIELD MGMT, L.P.
      By:  J.E. Flynn Capital, LLC, General Partner
         
      By:    /s/ Jonathan Isler
      Name:   Jonathan Isler   
      Title:   Attorney-in-Fact   
         
         
      DEERFIELD MANAGEMENT COMPANY, L.P.
      By:  Flynn Management LLC, General Partner
         
      By:    /s/ Jonathan Isler
      Name:   Jonathan Isler   
      Title:   Attorney-in-Fact     
         
         
      JAMES E. FLYNN
         
        /s/ Jonathan Isler
      Jonathan Isler, Attorney-in-Fact

     

     

     

     

    Schedule A

     

    Reporting Person Date Number of Shares Sold Price per Share ($)*

    Price

    Range ($)**

    Deerfield Partners, L.P. 5/3/2023 1,100 $3.55 $3.55 - $3.60
    Deerfield Partners, L.P. 5/4/2023 200 $3.55 N/A
    Deerfield Partners, L.P. 5/8/2023 1,945 $3.30 N/A
    Deerfield Partners, L.P. 5/9/2023 10,000 $3.00 $3.00 - $3.26
    Deerfield Partners, L.P. 5/12/2023 200 $2.70 N/A
    Deerfield Partners, L.P. 5/15/2023 200 $2.70 N/A
    Deerfield Partners, L.P. 5/16/2023 19,500 $2.70 $2.70 - $2.72
    Deerfield Partners, L.P. 5/17/2023 5,000 $2.70 N/A
    Deerfield Partners, L.P. 5/19/2023 236 $3.12 N/A
    Deerfield Partners, L.P. 5/19/2023 42,400 $2.79 $2.65 - $2.91
    Deerfield Partners, L.P. 5/22/2023 12,500 $2.95 N/A
    Deerfield Partners, L.P. 5/23/2023 7,185 $3.27 $3.23-$3.35

     

    * Price per share reported is a weighted average price. The Reporting Persons undertake to provide to the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in the “Price Range” column of this Schedule A.

     

    ** Other than with respect to the sale of 236 shares at a price per share of $3.12 on May 19, 2023, the shares were sold in multiple transactions at prices within the price range indicated (unless otherwise indicated).

     

     

     

     

     

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