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    SEC Form SC 13D/A filed by Kodiak Sciences Inc (Amendment)

    5/18/22 5:23:23 PM ET
    $KOD
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $KOD alert in real time by email
    SC 13D/A 1 tm2215907d1_sc13da.htm SC 13D/A

     

     

    SECURITIES AND EXCHANGE COMMISSION

    WASHINGTON, DC 20549

     

    SCHEDULE 13D

    (Rule 13d-102)

     

    INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT

    TO RULE 13d-l(a) AND AMENDMENTS THERETO FILED PURSUANT

    TO RULE 13d-2(a)

     

    (Amendment No. 9)*

     

    Kodiak Sciences Inc.

    (Name of Issuer)

     

    Common stock, par value $0.0001 per share

    (Title of Class of Securities)

     

    50015M109

     

    (CUSIP number)

     

    Alexandra A. Toohey

    Chief Financial Officer

    Baker Bros. Advisors LP

    860 Washington Street, 3rd Floor

    New York, NY 10014

    (212) 339-5690 

    (Name, address and telephone number of person authorized to receive notices and communications)

     

    May 16, 2022

     

    (Date of event which requires filing of this statement)

     

    If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of Rule 13d-1(e), 13d-1(f) or 13d-1(g), check the following box ¨.

     

    (Continued on the following pages)

     

    (Page 1 of 10 Pages)

    ________________________________

    *The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

     

    The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act.

     

     

     

     

     

    CUSIP No.    50015M109   Page   2   of   10   Pages

     

    1.

    NAMES OF REPORTING PERSONS

     

    Baker Bros. Advisors LP

    2.

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

    (a) ¨

    (b) ¨

    3.

    SEC USE ONLY

     

    4.

    SOURCE OF FUNDS*

    OO

    5.

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e) ¨

     

    6.

    CITIZENSHIP OR PLACE OF ORGANIZATION

    Delaware

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY EACH
    REPORTING
    PERSON WITH
    7. SOLE VOTING POWER: 16,431,091 (1)

    8. SHARED VOTING POWER: 0
    9. SOLE DISPOSITIVE POWER:16,431,091 (1)
    10. SHARED DISPOSITIVE POWER: 0

    11. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:16,431,091 (1)
    12. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* ¨
    13.

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

    31.6% (1)(2)

    14.

    TYPE OF REPORTING PERSON*

    IA, PN

     

    (1)Includes 43,356 shares of common stock (“Common Stock”) of Kodiak Sciences Inc. (the “Issuer”) underlying 43,356 non-qualified options exercisable for Common Stock (“Stock Options”).

     

    (2)Based on 51,953,631 shares of Common Stock outstanding as of April 29, 2022 as reported in the Issuer’s Form 10-Q filed with the Securities and Exchange Commission (“SEC”) on May 10, 2022.

     

     

     

     

    CUSIP No.    50015M109   Page   3   of   10   Pages

     

     

    1.

    NAMES OF REPORTING PERSONS

     

    Baker Bros. Advisors (GP) LLC

    2.

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

    (a) ¨

    (b) ¨

    3.

    SEC USE ONLY

     

    4.

    SOURCE OF FUNDS*

    OO

    5.

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e) ¨

     

    6.

    CITIZENSHIP OR PLACE OF ORGANIZATION

    Delaware

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY EACH
    REPORTING
    PERSON WITH
    7. SOLE VOTING POWER: 16,431,091 (1)
    8. SHARED VOTING POWER: 0
    9. SOLE DISPOSITIVE POWER: 16,431,091 (1)
    10. SHARED DISPOSITIVE POWER: 0

    11. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON: 16,431,091 (1)
    12. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* ¨
    13.

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

    31.6% (1)(2)

    14.

    TYPE OF REPORTING PERSON*

    HC, OO

     

    (1)Includes 43,356 shares of Common Stock underlying 43,356 Stock Options.

     

    (2)Based on 51,953,631 shares of Common Stock outstanding as of April 29, 2022 as reported in the Issuer’s Form 10-Q filed with the SEC on May 10, 2022.

     

     

     

     

    CUSIP No.    50015M109   Page   4   of   10   Pages

     

    1.

    NAMES OF REPORTING PERSONS

     

    Felix J. Baker

    2.

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

    (a) ¨

    (b) ¨

    3.

    SEC USE ONLY

     

    4.

    SOURCE OF FUNDS*

    OO

    5.

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e) ¨

     

    6.

    CITIZENSHIP OR PLACE OF ORGANIZATION

    United States

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY EACH
    REPORTING
    PERSON WITH
    7. SOLE VOTING POWER: 16,431,091 (1)
    8. SHARED VOTING POWER: 0
    9. SOLE DISPOSITIVE POWER: 16,431,091 (1)
    10. SHARED DISPOSITIVE POWER: 0

    11. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON: 16,431,091 (1)
    12. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* ¨
    13.

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

    31.6% (1)(2)

    14.

    TYPE OF REPORTING PERSON*

    IN, HC

     

    (1)Includes 43,356 shares of Common Stock underlying 43,356 Stock Options.

     

    (2)Based on 51,953,631 shares of Common Stock outstanding as of April 29, 2022 as reported in the Issuer’s Form 10-Q filed with the SEC on May 10, 2022.

     

     

     

     

    CUSIP No.    50015M109   Page   5   of   10   Pages

     

    1.

    NAMES OF REPORTING PERSONS

     

    Julian C. Baker

    2.

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

    (a) ¨

    (b) ¨

    3.

    SEC USE ONLY

     

    4.

    SOURCE OF FUNDS*

    OO

    5.

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e) ¨

     

    6.

    CITIZENSHIP OR PLACE OF ORGANIZATION

    United States

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY EACH
    REPORTING
    PERSON WITH
    7. SOLE VOTING POWER: 16,431,091 (1)
    8. SHARED VOTING POWER: 0
    9. SOLE DISPOSITIVE POWER: 16,431,091 (1)
    10. SHARED DISPOSITIVE POWER: 0

    11. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON: 16,431,091 (1)
    12. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* ¨
    13.

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

    31.6% (1)(2)

    14.

    TYPE OF REPORTING PERSON*

    IN, HC

     

    (1)Includes 43,356 shares of Common Stock underlying 43,356 Stock Options.
       
    (2)Based on 51,953,631 shares of Common Stock outstanding as of April 29, 2022 as reported in the Issuer’s Form 10-Q filed with the SEC on May 10, 2022.

     

     

     

     

    Amendment No. 9 to Schedule 13D

     

    This Amendment No. 9 to Schedule 13D amends and supplements the previously filed Schedules 13D filed by Baker Bros. Advisors LP (the “Adviser”), Baker Bros. Advisors (GP) LLC (the “Adviser GP”), Julian C. Baker and Felix J. Baker (collectively the “Reporting Persons”). Except as supplemented herein, such statements, as heretofore amended and supplemented, remain in full force and effect.

     

    The Adviser GP is the sole general partner of the Adviser. Pursuant to the management agreements, as amended, among the Adviser, Baker Brothers Life Sciences, L.P. (“Life Sciences”) and 667, L.P. (“667”, and together with Life Sciences, the “Funds”), and their respective general partners, the Funds’ respective general partners relinquished to the Adviser all discretion and authority with respect to the investment and voting power over securities held by the Funds, and thus the Adviser has complete and unlimited discretion and authority with respect to the Funds’ investments and voting power over investments.

     

    All capitalized terms contained herein but not otherwise defined shall have the meanings ascribed to such terms in the Schedule 13D, as amended. Information given in response to each item shall be deemed incorporated by reference in all other items, as applicable.

     

    ITEM 3. Source and Amount of Funds or Other Consideration.

     

    Item 3 of this Schedule 13D is supplemented and superseded, as the case may be, as follows:

     

    The disclosures in Item 5(c) are incorporated herein, by reference.

     

    ITEM 4. Purpose of the Transaction.

     

    Item 4 of Amendment No. 9 is supplemented and superseded, as the case may be, as follows:

     

    This Amendment No. 9 is being filed to report the acquisition of common stock (“Common Stock”) of Kodiak Sciences Inc. (the “Issuer”) reported in Item 5(c) that resulted in a more than 1 percent change in beneficial ownership. The disclosure regarding the purchases in Item 5(c) below is incorporated herein by reference.

     

    The Funds hold securities of the Issuer for investment purposes. The Reporting Persons or their affiliates may purchase additional securities or dispose of securities in varying amounts and at varying times depending upon the Reporting Persons’ continuing assessments of pertinent factors, including the availability of shares of Common Stock or other securities for purchase at particular price levels, the business prospects of the Issuer, other business investment opportunities, economic conditions, stock market conditions, money market conditions, the attitudes and actions of the board of directors (the “Board”) and management of the Issuer, the availability and nature of opportunities to dispose of securities of the Issuer and other plans and requirements of the particular entities. The Reporting Persons may discuss items of mutual interest with the Issuer, which could include items in subparagraphs (a) through (j) of Item 4 of Schedule 13D.

     

    Depending upon their assessments of the above factors, the Reporting Persons or their affiliates may change their present intentions as stated above and they may assess whether to make suggestions to the management of the Issuer regarding financing, and whether to acquire additional securities of the Issuer (by means of open market purchases, privately negotiated purchases, exercising some or all of the Stock Options (defined in Item 5), or otherwise) or to dispose of some or all of the securities of the Issuer under their control.

     

    Except as otherwise disclosed herein, at the present time, the Reporting Persons do not have any plans or proposals with respect to any extraordinary corporate transaction involving the Issuer including, without limitation, those matters described in subparagraphs (a) through (j) of Item 4 of Schedule 13D.

     

     

     

     

    ITEM 5. Interest in Securities of the Issuer.

     

    Item 5 of this Schedule 13D is hereby amended and restated in its entirety as follows:

     

    (a) and (b) Items 7 through 11 and 13 of each of the cover pages of this Amendment No. 9 are incorporated herein by reference.

     

    Set forth below is the aggregate number of shares of Common Stock directly held by each of the Funds and the percentage of the Issuer’s outstanding shares of Common Stock such holdings represent. The information set forth below is based on 51,953,631 shares of Common Stock outstanding as of April 29, 2022, as reported in the Issuer’s Form 10-Q filed with the Securities and Exchange Commission (“SEC”) on May 10, 2022. Such percentage figures are calculated in accordance with Rule 13d-3 under the Securities Exchange Act of 1934, as amended.

     

    Holder  Common Stock   Percent of Class Outstanding 
    667, L.P.   1,245,661    2.4%
    Baker Brothers Life Sciences, L.P.   15,142,074    29.2%
    Total   16,387,735    31.6%

     

    The Adviser GP, Felix J. Baker and Julian C. Baker as managing members of the Adviser GP, and the Adviser may be deemed to be beneficial owners of securities of the Issuer directly held by the Funds.

     

    Felix J. Baker, a managing member of the Adviser GP, currently serves on the Board. He is Chair of the Compensation Committee and serves on the Nominating/Governance Committee. Felix J. Baker, as compensation for his service on the Board, receives non-qualified stock options to purchase shares of Common Stock of the Issuer (“Stock Options”). Felix J. Baker holds 24,747 vested Stock Options that have an exercise price of $10.13 per share expiring June 2, 2029, 4,135 vested Stock Options that have an exercise price of $62.50 per share expiring June 7, 2030, 7,106 vested Stock Options that have an exercise price of $54.12 per share expiring June 29, 2030 and 7,368 Stock Options which were granted on June 30, 2021, that have an exercise price of $93.00 per share expiring June 29, 2031, which will vest on the earlier of June 30, 2022 or one day prior to the next annual meeting of the Issuer’s stockholders. The policy of the Funds and the Adviser does not permit managing members of the Adviser GP to receive compensation for serving as directors of the Issuer, and the Funds are instead entitled to the pecuniary interest in any compensation received for their service.

     

    The Adviser has voting and investment power over the Stock Options, Common Stock and Common Stock underlying such Stock Options and Common Stock received from the exercise of Stock Options by Felix J. Baker received as directors’ compensation. The Adviser GP, and Felix J. Baker and Julian C. Baker as managing members of the Adviser GP, may be deemed to have the power to vote or direct the vote of and the power to dispose or direct the disposition of the Stock Options, Common Stock, Common Stock received from the exercise of Stock Options and Common Stock underlying such Stock Options held by Felix J. Baker received as director’s compensation.

     

    (c) The following transactions in the Issuer’s Common Stock were effected by the Funds during the sixty days preceding the filing of this statement using their working capital. All purchase transactions were effected in the open market directly with a broker-dealer. Except as disclosed herein, none of the Reporting Persons or their affiliates has effected any other transactions in securities of the Issuer during the past 60 days.

     

     

     

     

    Name  Date   Number of Shares   Transaction   Price/Share   Footnote 
    667, L.P.   5/16/2022    11,410    Purchase    5.7101    1 
    Baker Brothers Life Sciences, L.P.   5/16/2022    93,690    Purchase    5.7101    1 
    667, L.P.   5/16/2022    1,846    Purchase    5.7475    2 
    Baker Brothers Life Sciences, L.P.   5/16/2022    15,154    Purchase    5.7475    2 
    667, L.P.   5/17/2022    989    Purchase    5.9866    3 
    Baker Brothers Life Sciences, L.P.   5/17/2022    8,118    Purchase    5.9866    3 
    667, L.P.   5/17/2022    11,043    Purchase    5.9877    4 
    Baker Brothers Life Sciences, L.P.   5/17/2022    90,674    Purchase    5.9877    4 
    667, L.P.   5/18/2022    1,115    Purchase    5.9537    5 
    Baker Brothers Life Sciences, L.P.   5/18/2022    9,157    Purchase    5.9537    5 
    667, L.P.   5/18/2022    22,266    Purchase    5.9686    6 
    Baker Brothers Life Sciences, L.P.   5/18/2022    182,827    Purchase    5.9686    6 
    667, L.P.   5/18/2022    912    Purchase    5.9689    7 
    Baker Brothers Life Sciences, L.P.   5/18/2022    7,489    Purchase    5.9689    7 

     

    (1) The reported price is a weighted average price. These shares were traded in multiple transactions at a prices ranging from $5.45 to $5.80. The Reporting Persons undertake to provide the staff of the Securities and Exchange Commission (the “Staff”), upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.

     

    (2) The reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from $5.71 to $5.80. The Reporting Persons undertake to provide the Staff, upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.

     

    (3) The reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from $5.98 to $6.00. The Reporting Persons undertake to provide the Staff, upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.

     

    (4) The reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from $5.88 to $6.06. The Reporting Persons undertake to provide the Staff, upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.

     

    (5) The reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from $5.93 to $6.01. The Reporting Persons undertake to provide the Staff, upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.

     

    (6) The reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from $5.87 to $6.00. The Reporting Persons undertake to provide the Staff, upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.

     

    (7) The reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from $5.92 to $6.05. The Reporting Persons undertake to provide the Staff, upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.

     

     

    (d) Certain securities of the Issuer are held directly by 667, a limited partnership the sole general partner of which is Baker Biotech Capital, L.P., a limited partnership the sole general partner of which is Baker Biotech Capital (GP), LLC. Julian C. Baker and Felix J. Baker are the managing members of Baker Biotech Capital (GP), LLC.

     

    Certain securities of the Issuer are held directly by Life Sciences, a limited partnership the sole general partner of which is Baker Brothers Life Sciences Capital, L.P., a limited partnership the sole general partner of which is Baker Brothers Life Sciences Capital (GP), LLC. Julian C. Baker and Felix J. Baker are the managing members of Baker Brothers Life Sciences Capital (GP), LLC.

     

    (e) Not applicable.

     

     

     

     

    SIGNATURE

     

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     

    May 18, 2022

     

     

    BAKER BROS. ADVISORS LP

     

    By: Baker Bros. Advisors (GP) LLC, its general partner

         
      By: /s/ Scott L. Lessing
        Name: Scott L. Lessing
    Title: President

     

      BAKER BROS. ADVISORS (GP) LLC
         
     

    By:

    /s/ Scott L. Lessing

        Name: Scott L. Lessing
    Title: President

     

      /s/ Julian C. Baker
      Julian C. Baker
     
      /s/ Felix J. Baker
      Felix J. Baker

     

     

     

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    • Kodiak Sciences upgraded by Jefferies with a new price target

      Jefferies upgraded Kodiak Sciences from Hold to Buy and set a new price target of $20.00

      12/9/24 7:57:06 AM ET
      $KOD
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • H.C. Wainwright initiated coverage on Kodiak Sciences with a new price target

      H.C. Wainwright initiated coverage of Kodiak Sciences with a rating of Neutral and set a new price target of $3.00

      9/5/24 7:49:18 AM ET
      $KOD
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Goldman resumed coverage on Kodiak Sciences with a new price target

      Goldman resumed coverage of Kodiak Sciences with a rating of Sell and set a new price target of $2.00

      12/11/23 7:49:48 AM ET
      $KOD
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $KOD
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

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    • SEC Form SC 13G/A filed by Kodiak Sciences Inc (Amendment)

      SC 13G/A - Kodiak Sciences Inc. (0001468748) (Subject)

      2/14/24 4:23:00 PM ET
      $KOD
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form SC 13G/A filed by Kodiak Sciences Inc (Amendment)

      SC 13G/A - Kodiak Sciences Inc. (0001468748) (Subject)

      1/26/24 11:49:38 AM ET
      $KOD
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form SC 13G/A filed by Kodiak Sciences Inc (Amendment)

      SC 13G/A - Kodiak Sciences Inc. (0001468748) (Subject)

      2/14/23 4:19:55 PM ET
      $KOD
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $KOD
    SEC Filings

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    • SEC Form DEFA14A filed by Kodiak Sciences Inc

      DEFA14A - Kodiak Sciences Inc. (0001468748) (Filer)

      4/22/25 4:12:08 PM ET
      $KOD
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form DEF 14A filed by Kodiak Sciences Inc

      DEF 14A - Kodiak Sciences Inc. (0001468748) (Filer)

      4/22/25 4:06:57 PM ET
      $KOD
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form S-8 filed by Kodiak Sciences Inc

      S-8 - Kodiak Sciences Inc. (0001468748) (Filer)

      3/27/25 4:33:37 PM ET
      $KOD
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $KOD
    Financials

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    • Kodiak Sciences to Report Fourth Quarter and Full-Year 2023 Financial Results and Host Business Updates Webcast on March 28, 2024

      PALO ALTO, Calif., March 26, 2024 /PRNewswire/ -- Kodiak Sciences Inc. (NASDAQ:KOD), a biopharmaceutical company committed to researching, developing and commercializing transformative therapeutics to treat high prevalence retinal diseases, announced today that it will report fourth quarter and full-year 2023 financial results on Thursday, March 28, 2024. Management will host a conference call and live webcast to discuss recent business highlights and provide a corporate update at 4:30 p.m. Eastern Time on March 28, 2024. To access the webcast, please register at https://edge.media-server.com/mmc/p/q4jdxku4/. A live audio webcast of the event will be available on the "Events and Presentatio

      3/26/24 6:15:00 AM ET
      $KOD
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Kodiak Sciences Announces Top-Line Results from its initial Phase 2b/3 Study of KSI-301 in Patients with Neovascular (Wet) Age-Related Macular Degeneration

      PALO ALTO, Calif., Feb. 23, 2022 /PRNewswire/ -- Kodiak Sciences Inc. (NASDAQ:KOD) today announced top-line results from its randomized, double-masked, active comparator-controlled Phase 2b/3 clinical trial evaluating the efficacy, durability and safety of KSI-301, a novel antibody biopolymer conjugate, in treatment-naïve subjects with neovascular (wet) age-related macular degeneration. The trial randomized 559 participants, approximately 80% of whom were enrolled in the United States. The study had two treatment arms: KSI-301 5mg on a flexible long-interval regimen and aflibercept 2mg on a fixed short-interval regimen. In the study, three monthly loading doses were administered to all subje

      2/23/22 6:00:00 AM ET
      $KOD
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care