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    SEC Form SC 13D/A filed by Takeda Pharmaceutical Company Limited (Amendment)

    9/14/21 6:13:13 AM ET
    $TAK
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $TAK alert in real time by email
    SC 13D/A 1 sc13da-091421.htm SC 13D/A Document


    UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549


    SCHEDULE 13D
    Under the Securities Exchange Act of 1934 (Amendment No. 1)*


    Molecular Templates, Inc.
    (Name of Issuer)


    Common Stock, $0.001 par value
    (Title of Class of Securities)


    608550 109
    (CUSIP Number)


    Takeda Pharmaceutical Company Limited
    12-10, Nihonbashi 2-Chome, Chuo-ku, Tokyo 103-8668, Japan
    Attn: Yoshihiro Nakagawa
    Tel: +81 3 3278-2111
    (Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)


    August 24, 2021
    (Date of Event Which Requires Filing of this Statement)


    If the filing person has previously filed a statement on Schedule 13G to report the acquisition which is the subject of this Schedule 13D, and is filing this schedule because of Rule 13d-1(e), 13d-1(f) or 13d-1(g) check the following box: ☐
    Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Rule 13d-7 for other parties to whom copies are to be sent.

    * The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

    The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).





    SCHEDULE 13D
    CUSIP No. 608550 109

    1
    NAME OF REPORTING PERSON:

    Takeda Pharmaceutical Company Limited
    2
    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
    (a) ☐    (b) ☐
    3
    SEC USE ONLY
    4
    SOURCE OF FUNDS*

    WC
    5
    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e) ☐
    6
    CITIZENSHIP OR PLACE OF ORGANIZATION

    Japan


    NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON
    WITH
    7
    SOLE VOTING POWER

    -0-
    8
    SHARED VOTING POWER

    - 2,314,659 -
    9
    SOLE DISPOSITIVE POWER

    -0-
    10
    SHARED DISPOSITIVE POWER

    - 2,314,659 -
    11
    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

    - 2,314,659 -
    12
    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* ☐
    13
    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

    4.1% (1)
    14
    TYPE OF REPORTING PERSON*

    CO

    (1) The percentage ownership is based on 56,142,400 shares of Common Stock outstanding as of August 9, 2021, as reported by Molecular Templates, Inc. in its Quarterly Report on Form 10-Q filed with the U.S. Securities and Exchange Commission on August 13, 2021.




    SCHEDULE 13D

    CUSIP No. 608550 109

    1
    NAME OF REPORTING PERSON:

    Millennium Pharmaceuticals, Inc.
    2
    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
    (a) ☐    (b) ☐
    3
    SEC USE ONLY
    4
    SOURCE OF FUNDS*

    WC
    5
    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e) ☐
    6
    CITIZENSHIP OR PLACE OF ORGANIZATION

    Delaware


    NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON
    WITH
    7
    SOLE VOTING POWER

    -0-
    8
    SHARED VOTING POWER

    - 2,314,659 -
    9
    SOLE DISPOSITIVE POWER

    -0-
    10
    SHARED DISPOSITIVE POWER

    - 2,314,659 -
    11
    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

    - 2,314,659 -
    12
    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* ☐
    13
    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

    4.1% (1)
    14
    TYPE OF REPORTING PERSON*

    CO

    (1) The percentage ownership is based on 56,142,400 shares of Common Stock outstanding as of August 9, 2021, as reported by Molecular Templates, Inc. in its Quarterly Report on Form 10-Q filed with the U.S. Securities and Exchange Commission on August 13, 2021.




    SCHEDULE 13D

    CUSIP No. 608550 109

    1
    NAME OF REPORTING PERSON:

    Takeda Pharmaceuticals U.S.A., Inc.
    2
    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
    (a) ☐    (b) ☐
    3
    SEC USE ONLY
    4
    SOURCE OF FUNDS*

    WC
    5
    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e) ☐
    6
    CITIZENSHIP OR PLACE OF ORGANIZATION

    Delaware


    NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON
    WITH
    7
    SOLE VOTING POWER

    -0-
    8
    SHARED VOTING POWER

    - 2,314,659 -
    9
    SOLE DISPOSITIVE POWER

    -0-
    10
    SHARED DISPOSITIVE POWER

    - 2,314,659 -
    11
    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

    - 2,314,659 -
    12
    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* ☐
    13
    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

    4.1% (1)
    14
    TYPE OF REPORTING PERSON*

    CO

    (1) The percentage ownership is based on 56,142,400 shares of Common Stock outstanding as of August 9, 2021, as reported by Molecular Templates, Inc. in its Quarterly Report on Form 10-Q filed with the U.S. Securities and Exchange Commission on August 13, 2021.



    SCHEDULE 13D

    CUSIP No. 608550 109

    1
    NAME OF REPORTING PERSON:

    Takeda Pharmaceuticals International AG
    2
    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
    (a) ☐    (b) ☐
    3
    SEC USE ONLY
    4
    SOURCE OF FUNDS*

    WC
    5
    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e) ☐
    6
    CITIZENSHIP OR PLACE OF ORGANIZATION

    Switzerland


    NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON
    WITH
    7
    SOLE VOTING POWER

    -0-
    8
    SHARED VOTING POWER

    - 2,314,659 -
    9
    SOLE DISPOSITIVE POWER

    -0-
    10
    SHARED DISPOSITIVE POWER

    - 2,314,659 -
    11
    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

    - 2,314,659 -
    12
    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* ☐
    13
    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

    4.1% (1)
    14
    TYPE OF REPORTING PERSON*

    CO

    (1) The percentage ownership is based on 56,142,400 shares of Common Stock outstanding as of August 9, 2021, as reported by Molecular Templates, Inc. in its Quarterly Report on Form 10-Q filed with the U.S. Securities and Exchange Commission on August 13, 2021.



    SCHEDULE 13D

    CUSIP No. 608550 109

    1
    NAME OF REPORTING PERSON:

    Takeda Pharma A/S
    2
    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
    (a) ☐    (b) ☐
    3
    SEC USE ONLY
    4
    SOURCE OF FUNDS*

    WC
    5
    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e) ☐
    6
    CITIZENSHIP OR PLACE OF ORGANIZATION

    Denmark


    NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON
    WITH
    7
    SOLE VOTING POWER

    -0-
    8
    SHARED VOTING POWER

    -0-
    9
    SOLE DISPOSITIVE POWER

    -0-
    10
    SHARED DISPOSITIVE POWER

    -0-
    11
    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

    -0-
    12
    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* ☐
    13
    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

    0%
    14
    TYPE OF REPORTING PERSON*

    CO




    SCHEDULE 13D

    CUSIP No. 608550 109

    1
    NAME OF REPORTING PERSON:

    Takeda A/S
    2
    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
    (a) ☐    (b) ☐
    3
    SEC USE ONLY
    4
    SOURCE OF FUNDS*

    WC
    5
    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e) ☐
    6
    CITIZENSHIP OR PLACE OF ORGANIZATION

    Denmark


    NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON
    WITH
    7
    SOLE VOTING POWER

    -0-
    8
    SHARED VOTING POWER

    -0-
    9
    SOLE DISPOSITIVE POWER

    -0-
    10
    SHARED DISPOSITIVE POWER

    -0-
    11
    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

    -0-
    12
    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* ☐
    13
    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

    0%
    14
    TYPE OF REPORTING PERSON*

    CO





    SCHEDULE 13D

    CUSIP No. 608550 109

    1
    NAME OF REPORTING PERSON:

    Takeda Europe Holdings B.V.
    2
    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
    (a) ☐    (b) ☐
    3
    SEC USE ONLY
    4
    SOURCE OF FUNDS*

    WC
    5
    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e) ☐
    6
    CITIZENSHIP OR PLACE OF ORGANIZATION

    Netherlands

    NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON
    WITH
    7
    SOLE VOTING POWER

    -0-
    8
    SHARED VOTING POWER

    -0-
    9
    SOLE DISPOSITIVE POWER

    -0-
    10
    SHARED DISPOSITIVE POWER

    -0-
    11
    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

    -0-
    12
    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* ☐
    13
    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

    0%
    14
    TYPE OF REPORTING PERSON*

    CO



    SCHEDULE 13D
    Amendment No. 1

    Molecular Templates, Inc.

    This Amendment No. 1 to the Schedule 13D (this “Amendment No. 1”) relates to the common stock, par value $0.001 per share (the “Common Stock”), of Molecular Templates, Inc., a Delaware corporation (the “Issuer”). The principal executive offices of the Issuer are located at 9301 Amberglen Blvd, Suite 100, Austin, Texas 78729, and amends the Schedule 13D filed with the SEC on August 10, 2017 (the “Original Schedule 13D” and, together with this Amendment No. 1, the “Schedule 13D”). Capitalized terms used and not defined in this Amendment No. 1 have the meanings set forth in the Original Schedule 13D.
    This Amendment No. 1 amends Item 2, Item 5 and Item 7 as set forth below. As a result of the transactions described herein, each of the Reporting Persons ceased to be the beneficial owner of more than five percent of the Common Stock. The filing of this Amendment No. 1 represents the final amendment to the Schedule 13D and constitutes an exit filing for the Reporting Persons.

    Item 2.    Identity and Background.

    Item 2 of the Schedule 13D is supplementally amended as follows:

    Since the filing of the Original Schedule 13D Takeda effected certain organizational restructurings, including the liquidation of Takeda Europe, which was completed on January 19, 2019 and the voluntary liquidation of Takeda A/S, which was initiated on February 19, 2019, but not yet complete. Takeda continues to be the indirect parent company of Millennium and Millennium remains a wholly-owned direct subsidiary of Takeda USA. Currently, Takeda owns 72.70% of Takeda USA, and Takeda International owns 27.30% of Takeda USA. Takeda owns 100% of Takeda International. Because of the relationship of Millennium to each of Takeda USA, Takeda International, and Takeda, each Reporting Person (other than Takeda Denmark, Takeda A/S and Takeda Europe) may be deemed to beneficially own the shares of Common Stock described herein. Takeda Denmark, Takeda A/S and Takeda Europe no longer beneficially own any shares of Common Stock.

    Item 5.    Interest in Securities of the Issuer.
    Paragraphs (a)-(c) and (e) of Item 5 of the Schedule 13D are amended and restated in their entirety as follows:
    The percentages used in this Item and in the rest of the Schedule 13D are calculated based on 56,142,400 shares of Common Stock outstanding as of August 9, 2021, as reported by Molecular Templates, Inc. in its Quarterly Report on Form 10-Q filed with the U.S. Securities and Exchange Commission on August 13, 2021.
    (a)-(b)— The information contained on the cover pages to this Amendment No. 1 and the information set forth or incorporated in Item 2 hereof are incorporated herein by reference.

    As of September 14, 2021, each Reporting Person (other than Takeda Denmark, Takeda A/S and Takeda Europe) may be deemed to beneficially own 2,314,659 shares of Common Stock, representing approximately 4.1% of the shares of Common Stock outstanding.

    (c)The Reporting Persons effected the following transactions in the Common Stock in open market transactions on the dates indicated on Exhibit 7 attached hereto, and such transactions are the only transactions effected with respect to the Common Stock during the sixty days prior to the date hereof by any of the Reporting Persons.

    (d)Not applicable.

    (e)As a result of the transactions described herein, on August 24, 2021 each of the Reporting Persons ceased to be the beneficial owner of more than five percent of the Common Stock. The filing of this Amendment No. 1 represents the final amendment to the Schedule 13D and constitutes an exit filing for the Reporting Persons.


    Item 7.    Material to Be Filed as Exhibits.

    Item 7 of the Schedule 13D is supplementally amended as follows:

    Exhibit 7 — Transactions in the Common Stock effected in the past 60 days



    SIGNATURE

    After reasonable inquiry and to the best of its knowledge and belief, the undersigned certifies that the information set forth in this statement is true, complete and correct.

    TAKEDA PHARMACEUTICAL COMPANY
    LIMITED
    By:/s/ Yoshihiro Nakagawa
    Name: Yoshihiro Nakagawa
    Title: Corporate Officer, Global General Counsel
    MILLENNIUM PHARMACEUTICALS, INC.
    By:
    /s/ Paul Sundberg
    Name: Paul Sundberg
    Title: Assistant Secretary
    TAKEDA PHARMACEUTICALS U.S.A., INC.
    By:
    /s/ Paul Sundberg
    Name: Paul Sundberg
    Title: Assistant Secretary
    TAKEDA PHARMACEUTICALS
    INTERNATIONAL AG
    By:
    /s/ Barbara Lenzlinger
    Name: Barbara Lenzlinger
    Title: Managing Officer
    By:
    /s/ Hugo Bert Antoine Marie Souren
    Name: Hugo Bert Antoine Marie Souren
    Title: ppa. Authorized Signatory
    TAKEDA PHARMA A/S
    By:
    /s/ Christian Ramskov
    Name: Christian Ramskov
    Title: Head of Finance
    By:
    /s/ Duarte Marchand
    Name: Duarte Marchand
    Title: Head of Nordics
    TAKEDA A/S IN LIQUIDATION
    By:
    /s/ Ole Nørgaard
    Name: Ole Nørgaard
    Title: Liquidator
    By:
    /s/ Troels Tuxen
    Name: Troels Tuxen
    Title: Liquidator



    Exhibit 7

    The following table sets forth all transactions with respect to shares of Common Stock effected in the last sixty days by the Reporting Persons on behalf of the Reporting Persons in respect of the Shares. All such transactions were sales of Common Stock effected in the open market, as noted in the table below.
     
    NATURE OF TRANSACTION  DATE OF
    TRANSACTION
      AMOUNT OF
    SECURITIES
      PRICE PER
    SHARE($)
    Sale of Common Stock
        2021.08.18     2,133   $7.00 
    Sale of Common Stock
        2021.08.23     93,818   $6.66 
    Sale of Common Stock
        2021.08.24     62,350   $6.53
    Sale of Common Stock
        2021.08.25     85,533   $6.52 
    Sale of Common Stock
        2021.08.26     38,047   $6.50 
    Sale of Common Stock
        2021.08.26     17,000   $6.51 
    Sale of Common Stock
        2021.08.27     77,100   $6.50 
    Sale of Common Stock
        2021.08.30     37,836   $6.65 
    Sale of Common Stock
        2021.08.31     23,916   $6.53 
    Sale of Common Stock
        2021.09.01     18,140   $6.53 
    Sale of Common Stock
        2021.09.02     86,459   $6.50 
    Sale of Common Stock
        2021.09.03     8,797   $6.50 
    Sale of Common Stock
        2021.09.07     15,824   $6.53 
    Sale of Common Stock
        2021.09.10     4,764   $6.24 
    Sale of Common Stock
        2021.09.13     36,617   $6.11

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    • Takeda Announces FY2024 Full Year Results and FY2025 Outlook Reflecting Growth & Launch Products Momentum, Strong Cash Flow Generation and Late-Stage Pipeline Progress

      Core Revenue Growth of 7.4% at Actual Exchange Rates (AER), + 2.8% at Constant Exchange Rate (CER) in FY2024 Core Operating Profit Growth of 4.9% at CER with Efficiency Program Driving Cost Savings Up to Six New Molecular Entities in Phase 3 Development in FY2025 with Three Phase 3 Data Readouts Recently Completed or Anticipated FY2025 Outlook for Broadly Flat Revenue and Core Profit Reflecting Product Momentum and Increasing Investment in New Launch Preparation Proposed Dividend Increase from JPY 196 to JPY 200 Takeda ((4502, NYSE:TAK) today announced financial results for fiscal year 2024 (period ended March 31, 2025) with continued strong momentum in Growth & Launch Products o

      5/8/25 2:36:00 AM ET
      $TAK
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • BioLife Plasma Services Introduces the New Fresenius Kabi Adaptive Nomogram Across its U.S. Network of Plasma Donation Centers

      -New Technology Optimizes Plasma Collection Resulting in Efficiency Gains -Helps Strengthen Plasma Supply Used to Produce Lifesaving and Life-Sustaining Medicines BioLife Plasma Services, part of Takeda (NYSE:TAK), today announced that it has begun introducing the new Fresenius Kabi Adaptive Nomogram across its U.S. network of plasma donation centers. The new Adaptive Nomogram is used on the Aurora Xi Plasmapheresis System, which is in more than half of BioLife's U.S. plasma donation centers. This new technology will be running in all BioLife donation centers using the Aurora Xi Plasmapheresis System by the end of December 2025. This press release features multimedia. View the full relea

      5/5/25 8:00:00 AM ET
      $TAK
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Takeda Awards $13.8 Million to U.S. Nonprofit Partners to Promote Healthy Eating and Expand STEM Education

      Annual Grants Deepen Takeda's Commitment to Improving Health Through Community-Based Programs Takeda Publishes U.S. Community Impact Report Highlighting Progress toward a More Equitable Health Ecosystem See the full release at Takeda.com View source version on businesswire.com: https://www.businesswire.com/news/home/20250430215346/en/ Media Contact: Takeda Media Relations [email protected]

      4/30/25 8:05:00 AM ET
      $TAK
      Biotechnology: Pharmaceutical Preparations
      Health Care

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    • Vatroslav Mateljic Appointed General Manager of Takeda Canada

      Vatroslav Mateljic's innovative approach and commitment to transforming the lives of patients will strengthen Takeda's leadership position in the Canadian biopharmaceutical sectorTORONTO, Sept. 16, 2024 /CNW/ - Takeda Canada Inc. ("Takeda Canada") is pleased to announce the appointment of Vatroslav (Vatro) Mateljic as its new General Manager to lead the Canadian operations of Japan's largest pharmaceutical company. Mr. Mateljic has held a number of executive leadership roles in sales, marketing and country management over his 25-year career in the pharmaceutical industry.  Mos

      9/16/24 8:39:00 AM ET
      $TAK
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Takeda Announces Candidates for Board of Directors at Upcoming Shareholders Meeting

      Takeda (TYO:4502, NYSE:TAK) today announced that its Board of Directors decided on March 26, 2024 (CET) to propose candidates for Board of Directors at the 148th Ordinary General Meeting of Shareholders to be held on June 26, 2024. Mr. Milano Furuta, currently president of the Japan Pharma Business Unit (JPBU), will succeed Mr. Constantine Saroukos as chief financial officer (CFO) effective April 1, 2024. Takeda will propose Mr. Furuta as a new candidate for board director at the Ordinary General Meeting of Shareholders. If approved by shareholders, Mr. Furuta will join the Board effective June 26, 2024. Mr. Constantine Saroukos, who expressed his intention to retire as CFO, will leave

      3/26/24 7:07:00 PM ET
      $TAK
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Takeda and The New York Academy of Sciences Announce 2024 Innovators in Science Award Winners

      2024 Award Celebrates Outstanding Research in Cancer Immunology Winners Discovered Novel Connections Between the Immune System and Cancer Recipients Each Receive Unrestricted USD 200,000 Awards Takeda ((TAK) and The New York Academy of Sciences today announced the winners of the 2024 Innovators in Science Award for their excellence in, and commitment to, innovative science that has significantly advanced the field of research in cancer immunology. Each winner receives an unrestricted prize of USD 200,000. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20231205723166/en/ The 2024 Senior Scientist winner is Robert D. Schre

      12/5/23 8:00:00 AM ET
      $TAK
      Biotechnology: Pharmaceutical Preparations
      Health Care