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    SEC Form SC 13G filed by eFFECTOR Therapeutics Inc.

    3/7/23 5:25:54 PM ET
    $EFTR
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $EFTR alert in real time by email
    SC 13G 1 tm238685d1_sc13g.htm SC 13G

     

     

     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    Washington, D.C. 20549

     

    SCHEDULE 13G

     

    Under the Securities Exchange Act of 1934

    (Amendment No. )*

     

    eFFECTOR Therapeutics, Inc.

    (Name of Issuer)

     

    Common stock, $0.0001 par value per share

    (Title of Class of Securities)

     

    28202V108

    (CUSIP Number)

     

    August 25, 2021

    (Date of Event Which Requires Filing of this Statement)

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

     

      ¨ Rule 13d-1(b)
         
      x Rule 13d-1(c)
         
      ¨ Rule 13d-1(d)

     

    *The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

     

    The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

     

     

     

     

     

     

    CUSIP No.   28202V108
    1.

    Names of Reporting Persons

    Altitude Life Science Ventures Fund II, L.P.

    2. Check the Appropriate Box if a Member of a Group (See Instructions)
     

    (a)

    (b)

    ¨

    x (1)

    3. SEC Use Only
    4.

    Citizenship or Place of Organization

    Delaware

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person With

    5.

    Sole Voting Power

    0

    6.

    Shared Voting Power

    1,413,175 shares (2)

    7.

    Sole Dispositive Power

    0

    8.

    Shared Dispositive Power

    1,413,175 shares (2)

    9.

    Aggregate Amount Beneficially Owned by Each Reporting Person

    1,413,175 shares (2)

    10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)    ¨
    11.

    Percent of Class Represented by Amount in Row (9)

    3.4% (3)

    12.

    Type of Reporting Person (See Instructions)

    PN

             

    (1)This Schedule 13G is filed by Altitude Life Science Ventures Fund II, L.P. (“Altitude II”), Altitude Life Science Ventures Side Fund II, L.P. (“Altitude II SF”), Altitude Life Science Ventures II, LLC (“Altitude GP”) and David Maki (“Maki” and, with Altitude II, Altitude II SF and Altitude GP, collectively, the “Reporting Persons”). The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.

     

    (2)The shares are directly held by Altitude II. Altitude II GP serves as sole general partner of Altitude II and Maki is the managing member of Altitude II GP. Each of Altitude II GP and Maki shares voting and dispositive power over the shares held by Altitude II. The foregoing amount does not include 178,703 shares of Common Stock potentially issuable to Altitude II upon the satisfaction of certain earn-out conditions.

     

    (3)This percentage is calculated based upon 41,893,140 shares of Common Stock outstanding as of October 31, 2022, as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission (the “SEC”) on November 7, 2022.

     

     2 

     

     

    CUSIP No.   28202V108
    1.

    Names of Reporting Persons

    Altitude Life Science Ventures Side Fund II, L.P.

    2. Check the Appropriate Box if a Member of a Group (See Instructions)
     

    (a)

    (b)

    ¨

    x (1)

    3. SEC Use Only
    4.

    Citizenship or Place of Organization

    Delaware

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person With

    5.

    Sole Voting Power

    0

    6.

    Shared Voting Power

    1,413,175 shares (2)

    7.

    Sole Dispositive Power

    0

    8.

    Shared Dispositive Power

    1,413,175 shares (2)

    9.

    Aggregate Amount Beneficially Owned by Each Reporting Person

    1,413,175 shares (2)

    10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)    ¨
    11.

    Percent of Class Represented by Amount in Row (9)

    3.4% (3)

    12.

    Type of Reporting Person (See Instructions)

    PN

             

    (1)This Schedule 13G is filed by the Reporting Persons. The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.

     

    (2)The shares are directly held by Altitude II SF. Altitude II GP serves as sole general partner of Altitude II SF and Maki is the managing member of Altitude II GP. Each of Altitude II GP and Maki shares voting and dispositive power over the shares held by Altitude II SF. The foregoing amount does not include 178,703 shares of Common Stock potentially issuable to Altitude II SF upon the satisfaction of certain earn-out conditions.

     

    (3)This percentage is calculated based upon 41,893,140 shares of Common Stock outstanding as of October 31, 2022, as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the SEC on November 7, 2022.

     

     3 

     

     

    CUSIP No.   28202V108
    1.

    Names of Reporting Persons

    Altitude Life Science Ventures II, LLC

    2. Check the Appropriate Box if a Member of a Group (See Instructions)
     

    (a)

    (b)

    ¨

    x (1)

    3. SEC Use Only
    4.

    Citizenship or Place of Organization

    Delaware

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person With

    5.

    Sole Voting Power

    0

    6.

    Shared Voting Power

    2,826,350 shares (2) 

    7.

    Sole Dispositive Power

    0

    8.

    Shared Dispositive Power

    2,826,350 shares (2) 

    9.

    Aggregate Amount Beneficially Owned by Each Reporting Person

    2,826,350 shares (2) 

    10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)    ¨
    11.

    Percent of Class Represented by Amount in Row (9)

    6.7% (3)

    12.

    Type of Reporting Person (See Instructions)

    OO

             

    (1)This Schedule 13G is filed by the Reporting Persons. The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.

     

    (2)Includes 1,413,175 shares of Common Stock that are directly held by Altitude II and 1,413,175 shares of Common Stock that are directly held by Altitude II SF. Altitude II GP serves as sole general partner of Altitude II and Altitude II SF, and Maki is the managing member of Altitude II GP. Each of Altitude II GP and Maki shares voting and dispositive power over the shares held by Altitude II and Altitude II SF. The foregoing amount does not include 178,703 shares of Common Stock potentially issuable to Altitude II and 178,703 shares of Common Stock potentially issuable to Altitude II SF upon the satisfaction of certain earn-out conditions.

     

    (3)This percentage is calculated based upon 41,893,140 shares of Common Stock outstanding as of October 31, 2022, as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the SEC on November 7, 2022.

     

     4 

     

     

    CUSIP No.   28202V108
    1.

    Names of Reporting Persons

    David Maki

    2. Check the Appropriate Box if a Member of a Group (See Instructions)
     

    (a)

    (b)

    ¨

    x (1)

    3. SEC Use Only
    4.

    Citizenship or Place of Organization

    United States

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person With

    5.

    Sole Voting Power

    0

    6.

    Shared Voting Power

    2,826,350 shares (2)

    7.

    Sole Dispositive Power

    0

    8.

    Shared Dispositive Power

    2,826,350 shares (2)

    9.

    Aggregate Amount Beneficially Owned by Each Reporting Person

    2,826,350 shares (2)

    10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)    ¨
    11.

    Percent of Class Represented by Amount in Row (9)

    6.7% (3)

    12.

    Type of Reporting Person (See Instructions)

    IN

             

     

    (1)This Schedule 13G is filed by the Reporting Persons. The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.

     

    (2)Includes 1,413,175 shares of Common Stock that are directly held by Altitude II and 1,413,175 shares of Common Stock that are directly held by Altitude II SF. Altitude II GP serves as sole general partner of Altitude II and Altitude II SF, and Maki is the managing member of Altitude II GP. Each of Altitude II GP and Maki shares voting and dispositive power over the shares held by Altitude II and Altitude II SF. The foregoing amount does not include 178,703 shares of Common Stock potentially issuable to Altitude II and 178,703 shares of Common Stock potentially issuable to Altitude II SF upon the satisfaction of certain earn-out conditions.

     

    (3)This percentage is calculated based upon 41,893,140 shares of Common Stock outstanding as of October 31, 2022, as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the SEC on November 7, 2022.

     

     5 

     

     

    Item 1.

     

      (a) Name of Issuer
        eFFECTOR Therapeutics, Inc.

      (b) Address of Issuer’s Principal Executive Offices
        142 North Cedros Avenue, Suite B
        Solana Beach, CA 92075

     

    Item 2.

     

      (a) Name of Person Filing Altitude Life Science Ventures Fund II, L.P. (“Altitude II”)
        Altitude Life Science Ventures Side Fund II, L.P. (“Altitude II SF”)
        Altitude Life Science Ventures II, LLC (“Altitude GP”)
        David Maki (“Maki”)

      (b) Address of Principal Business Office or, if none, Residence
        1014 Market Street, Suite 200, Kirkland, WA 98074

      (c) Citizenship

      Entities: Altitude II - Delaware
        Altitude II SF - Delaware
        Altitude II GP - Delaware
             
      Individuals: Maki - United States

      (d) Title of Class of Securities
        Common stock, $0.0001 par value per share (“Common Stock”)

      (e) CUSIP Number
        28202V108

     

    Item 3. If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
       
      Not applicable

     

     6 

     

     

    Item 4. Ownership
       
      The following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1 is provided as of March 7, 2023:

     

    Reporting Persons  Shares Held
    Directly
       Sole
    Voting
    Power
       Shared
    Voting
    Power
       Sole
    Dispositive
    Power
       Shared
    Dispositive
    Power
       Beneficial
    Ownership
       Percentage
    of Class (3)
     
    Altitude II (1)   1,413,175    0    1,413,175    0    1,413,175    1,413,175    3.4%
    Altitude II SF (2)   1,413,175    0    1,413,175    0    1,413,175    1,413,175    3.4%
    Altitude II GP (1) (2)   0    0    2,826,350    0    2,826,350    2,826,350    6.7%
    Maki (1) (2)   0    0    2,826,350    0    2,826,350    2,826,350    6.7%

     

      (1)Includes 1,413,175 shares of Common Stock that are directly held by Altitude II. Altitude II GP serves as sole general partner of Altitude II and Maki is the managing member of Altitude II GP. Each of Altitude II GP and Maki shares voting and dispositive power over the shares held by Altitude II. The foregoing amount does not include 178,703 shares of Common Stock potentially issuable to Altitude II upon the satisfaction of certain earn-out conditions.
      (2)Includes 1,413,175 shares of Common Stock that are directly held by Altitude II SF. Altitude II GP serves as sole general partner of Altitude II SF and Maki is the managing member of Altitude II GP. Each of Altitude II GP and Maki shares voting and dispositive power over the shares held by Altitude II SF. The foregoing amount does not include 178,703 shares of Common Stock potentially issuable to Altitude II SF upon the satisfaction of certain earn-out conditions.
      (3)This percentage is calculated based upon 41,893,140 shares of Common Stock outstanding as of October 31, 2022, as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the SEC on November 7, 2022.

     

    Item 5. Ownership of Five Percent or Less of a Class
       
      If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following   ¨
     
    Item 6. Ownership of More than Five Percent on Behalf of Another Person
       
      Not applicable
     
    Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person
       
      Not applicable
     
    Item 8. Identification and Classification of Members of the Group
       
      Not applicable
     
    Item 9. Notice of Dissolution of Group
       
      Not applicable
     
    Item 10. Certification
       
      By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having such purpose or effect.

     

     7 

     

     

    Signature

     

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     

    Dated: March 7, 2023

     

    Altitude Life Science Ventures Fund II, L.P.  
       
    By: Altitude Life Science Ventures II, LLC  
    its General Partner  
       
    By: /s/ David Maki  
      Name: David Maki  
      Title: Managing Member  
       
    Altitude Life Science Ventures Side Fund II, L.P.  
       
    By: Altitude Life Science Ventures II, LLC  
    its General Partner  
       
    By: /s/ David Maki  
      Name: David Maki  
      Title: Managing Member  
       
    Altitude Life Science Ventures II, LLC  
       
    By: /s/ David Maki  
      Name: David Maki  
      Title: Managing Member  

     

    /s/ David Maki  
    David Maki  

     

      ATTENTION  
    Intentional misstatements or omissions of fact constitute Federal Criminal Violations (See 18 U.S.C. 1001).

     

     8 

     

     

    Exhibit(s):

     

    AJoint Filing Agreement

     

     9 

     

     

    EXHIBIT A

     

    JOINT FILING AGREEMENT

     

    We, the undersigned, hereby express our agreement that the attached Schedule 13G (or any amendments thereto) relating to the Common Stock of eFFECTOR Therapeutics, Inc. is filed on behalf of each of us.

     

    Dated: March 7, 2023

     

    Altitude Life Science Ventures Fund II, L.P.  
       
    By: Altitude Life Science Ventures II, LLC  
    its General Partner  
       
    By: /s/ David Maki  
      Name: David Maki  
      Title: Managing Member  
       
    Altitude Life Science Ventures Side Fund II, L.P.  
       
    By: Altitude Life Science Ventures II, LLC  
    its General Partner  
       
    By: /s/ David Maki  
      Name: David Maki  
      Title: Managing Member  
       
    Altitude Life Science Ventures II, LLC  
       
    By: /s/ David Maki  
      Name: David Maki  
      Title: Managing Member  

     

    /s/ David Maki  
    David Maki  

     

     10 

     

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    • SEC Form 4 filed by Director Ehrlich Christopher B

      4 - eFFECTOR Therapeutics, Inc. (0001828522) (Issuer)

      6/13/24 6:25:33 PM ET
      $EFTR
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $EFTR
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    • eFFECTOR Therapeutics Announces it will Wind Down Operations as it Seeks Strategic Alternatives and Expects to be Delisted from Nasdaq

      SOLANA BEACH, Calif. and REDWOOD CITY, Calif., June 24, 2024 (GLOBE NEWSWIRE) -- eFFECTOR Therapeutics, Inc. (NASDAQ:EFTR) today announced that the Company has terminated its employees and will wind down it operations, including seeking potential strategic alternatives for the Company's development programs. This decision was made at a special meeting of the board of directors. Further, as previously disclosed, the Company's securities do not presently meet the continued listing requirements of the Nasdaq Stock Market and its securities would be subject to delisting if the Company fails to regain compliance during the required compliance period. The Company plans to voluntarily request a d

      6/24/24 7:00:00 AM ET
      $EFTR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • eFFECTOR Therapeutics to Collaborate with the Dana-Farber Cancer Institute on an Investigator-Sponsored Phase 2 Clinical Trial Evaluating Zotatifin as Combination Treatment in ER+ Endometrial Cancer and in Low Grade Serous Ovarian Cancer

      SOLANA BEACH, Calif. and REDWOOD CITY, Calif., May 20, 2024 (GLOBE NEWSWIRE) -- eFFECTOR Therapeutics, Inc. (NASDAQ:EFTR), a leader in the development of selective translation regulator inhibitors (STRIs) for the treatment of cancer, today announced a collaboration to conduct an investigator-sponsored trial (IST) evaluating zotatifin in combination with abemaciclib and letrozole in patients with estrogen receptor-positive (ER+) endometrial cancer and low grade serous ovarian cancer at the Dana-Farber Cancer Institute (DFCI) under the direction of Panagiotis Konstantinopoulos, M.D., Ph.D., Director of Translational Research and attending oncologist in the Division of Gynecologic Oncology at

      5/20/24 8:30:00 AM ET
      $EFTR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • eFFECTOR Therapeutics Reports First Quarter 2024 Financial Results and Provides Corporate Update

      Dose escalation of zotatifin in the ZFA triplet ongoing at 0.14 mg/kg, with RP2D expected in H2 2024 Raised $15.0 million in gross proceeds from registered direct financing, extending cash runway into first quarter of 2025 SOLANA BEACH, Calif. and REDWOOD CITY, Calif., May 09, 2024 (GLOBE NEWSWIRE) -- eFFECTOR Therapeutics, Inc. (NASDAQ:EFTR), a leader in the development of selective translation regulator inhibitors (STRIs) for the treatment of cancer, today reported financial results for the first quarter ended March 31, 2024, and provided a corporate update. "We had a productive first quarter marked by continued progress in the zotatifin program, including successful completion of the

      5/9/24 4:01:00 PM ET
      $EFTR
      Biotechnology: Pharmaceutical Preparations
      Health Care