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    SEC Form SC 13G filed by Evelo Biosciences Inc.

    7/21/23 8:00:58 AM ET
    $EVLO
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $EVLO alert in real time by email
    SC 13G 1 d529593dsc13g.htm SC 13G SC 13G

     

     

    SECURITIES AND EXCHANGE COMMISSION

    Washington, D.C. 20549

     

     

    SCHEDULE 13G

    Under the Securities Exchange Act of 1934

    (Amendment No.     )*

     

     

    Evelo Biosciences, Inc.

    (Name of Issuer)

    Common Stock, par value $0.001 per share

    (Title of Class of Securities)

    299734202

    (CUSIP Number)

    July 11, 2023

    (Date of Event Which Requires Filing of this Statement)

     

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

    ☐ Rule 13d-1(b)

    ☒ Rule 13d-1(c)

    ☐ Rule 13d-1(d)

     

    *

    The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

    The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

     

     

     


    CUSIP No. 299734202

     

      1    

      NAMES OF REPORTING PERSONS

     

      HarbourVest Partners L.P.

      2  

      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)

      (a)  ☐        (b)  ☐

     

      3  

      SEC USE ONLY

     

      4  

      CITIZENSHIP OR PLACE OF ORGANIZATION

     

      Delaware

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

       5    

      SOLE VOTING POWER

     

      0

       6  

      SHARED VOTING POWER

     

      1,451,876

       7  

      SOLE DISPOSITIVE POWER

     

      0

       8  

      SHARED DISPOSITIVE POWER

     

      1,451,876

      9    

      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

      1,451,876

    10  

      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)

     

      ☐

    11  

      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

     

      8.8%

    12  

      TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

     

      IA


    CUSIP No. 299734202

     

      1    

      NAMES OF REPORTING PERSONS

     

      HarbourVest Partners, LLC

      2  

      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)

      (a)  ☐        (b)  ☐

     

      3  

      SEC USE ONLY

     

      4  

      CITIZENSHIP OR PLACE OF ORGANIZATION

     

      Delaware

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

       5    

      SOLE VOTING POWER

     

      0

       6  

      SHARED VOTING POWER

     

      1,451,876

       7  

      SOLE DISPOSITIVE POWER

     

      0

       8  

      SHARED DISPOSITIVE POWER

     

      1,451,876

      9    

      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

      1,451,876

    10  

      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)

     

      ☐

    11  

      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

     

      8.8%

    12  

      TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

     

      IA


    CUSIP No. 299734202

     

      1    

      NAMES OF REPORTING PERSONS

     

      SMRS-TOPE LLC

      2  

      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)

      (a)  ☐        (b)  ☐

     

      3  

      SEC USE ONLY

     

      4  

      CITIZENSHIP OR PLACE OF ORGANIZATION

     

      Delaware

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

       5    

      SOLE VOTING POWER

     

      1,451,876

       6  

      SHARED VOTING POWER

     

      0

       7  

      SOLE DISPOSITIVE POWER

     

      1,451,876

       8  

      SHARED DISPOSITIVE POWER

     

      0

      9    

      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

      1,451,876

    10  

      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)

     

      ☐

    11  

      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

     

      8.8%

    12  

      TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

     

      OO


    CUSIP No. 299734202

     

      1    

      NAMES OF REPORTING PERSONS

     

      HVST-TOPE LLC

      2  

      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)

      (a)  ☐        (b)  ☐

     

      3  

      SEC USE ONLY

     

      4  

      CITIZENSHIP OR PLACE OF ORGANIZATION

     

      Delaware

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

       5    

      SOLE VOTING POWER

     

      0

       6  

      SHARED VOTING POWER

     

      1,451,876

       7  

      SOLE DISPOSITIVE POWER

     

      0

       8  

      SHARED DISPOSITIVE POWER

     

      1,451,876

      9    

      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

      1,451,876

    10  

      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)

     

      ☐

    11  

      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

     

      8.8%

    12  

      TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

     

      OO


    CUSIP No. 299734202

    Item 1.

     

      (a)

    Name of Issuer:

    Evelo Biosciences, Inc. (the “Issuer”)

     

      (b)

    Address of Issuer’s Principal Executive Offices:

    620 Memorial Drive

    Cambridge, MA 02139

    (617) 577-0300

    Item 2.

     

      (a)

    Name of Person Filing:

    HarbourVest Partners, LLC

    HarbourVest Partners L.P.

    HVST-TOPE LLC

    SMRS-TOPE LLC

    SMRS-TOPE LLC, HVST-TOPE LLC, HarbourVest Partners L.P. and HarbourVest Partners, LLC have entered into a Joint Filing Agreement, dated July 21, 2023, a copy of which is filed with this Schedule 13G as Exhibit 99.1, pursuant to which such reporting persons agreed to file this statement and any amendments thereto jointly in accordance with the provisions of Rule 13d-1(k)(1) under the Securities Exchange Act of 1934.

     

      (b)

    Address of Principal Business Office or, if none, Residence:

    The principal business office of each reporting person is One Financial Center, Boston, MA 0211.

     

      (c)

    Citizenship:

    Reporting entities are all organized and exist under the laws of the State of Delaware.

     

      (d)

    Title of Class of Securities:

    Common stock, par value $0.001 per share

     

      (e)

    CUSIP Number:

    299734202


    Item 3.

    If this statement is filed pursuant to §§240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a:

     

    (a)      ☐      Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
    (b)    ☐    Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
    (c)    ☐    Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
    (d)    ☐    Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
    (e)    ☐    An investment adviser in accordance with §240.13d-1(b) (1)(ii)(E);
    (f)    ☐    An employee benefit plan or endowment fund in accordance with §240.13d-1(b) (1)(ii)(F);
    (g)    ☐    A parent holding company or control person in accordance with §240.13d-1(b) (1)(ii)(G);
    (h)    ☐    A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
    (i)    ☐    A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
    (j)    ☐    A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J);
    (k)    ☐   

    Group, in accordance with § 240.13d-1(b)(1)(ii)(K).

    N/A

     

    Item 4.

    Ownership

    Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1.

     

    (a)

    Amount beneficially owned:

    Consists of 1,451,876 shares of common stock owned directly by SMRS-TOPE LLC. HarbourVest Partners, LLC (“HarbourVest”) is the General Partner of HarbourVest Partners L.P., which is the Manager of HVST-TOPE LLC, which is the Managing Member of SMRS-TOPE LLC. Each of HarbourVest, HarbourVest Partners L.P. and HVST-TOPE LLC may be deemed to have a beneficial interest in the shares held by SMRS-TOPE LLC.

    Voting and investment power over the securities owned directly by SMRS-TOPE LLC is exercised by the Investment Committee of HarbourVest. Each of HarbourVest, HarbourVest Partners L.P. and HVST-TOPE LLC and the members of the HarbourVest Investment Committee disclaim beneficial ownership of the shares held directly by SMRS-TOPE LLC.

     

    (b)

    Percent of class:

    8.8% (based on the Issuer’s aggregate of 16,571,838 shares of common stock outstanding, based on 5,546,504 shares of common stock outstanding as of May 8, 2023, as reported in the Issuer’s Quarterly Report on Form 10-Q, filed with the SEC on May 15, 2023, and after giving effect to the Issuer’s 1-for-20 reverse stock split of its common stock on June 29, 2023, as reported in the Issuer’s Current Report on Form 8-K, filed with the SEC on June 29, 2023, and the issuance of 11,025,334 shares of common stock on July 11, 2023, as reported in the Issuer’s Current Report on Form 8-K, filed with the SEC on July 12, 2023)

     

    (c)

    Number of shares as to which the person has:

    (i) Sole power to vote or to direct the vote:

    SMRS-TOPE LLC has the sole power to vote or to direct the vote of 1,451,876 shares of common stock.


    (ii) Shared power to vote or to direct the vote:

    HarbourVest, HarbourVest Partners L.P. and HVST-TOPE LLC may be deemed to have shared power to vote or direct the vote of 1,451,876 shares of common stock. Each of HarbourVest, HarbourVest Partners L.P. and HVST-TOPE LLC disclaim such beneficial ownership of such shares.

    (iii) Sole power to dispose or to direct the disposition:

    SMRS-TOPE LLC has the sole power to dispose or to direct the disposition of 1,451,876 shares of common stock.

    (iv) Shared power to dispose or to direct the disposition:

    HarbourVest, HarbourVest Partners L.P. and HVST-TOPE LLC may be deemed to have shared power to dispose or direct the disposition of 1,451,876 shares of common stock. Each of HarbourVest, HarbourVest Partners L.P. and HVST-TOPE LLC disclaim such beneficial ownership of such shares.

     

    Item 5.

    Ownership of Five Percent or Less of a Class.

    If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following ☐:

     

    Item 6.

    Ownership of More than Five Percent on Behalf of Another Person.

    See item 4 above.

     

    Item 7.

    Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person.

    Not Applicable.

     

    Item 8.

    Identification and Classification of Members of the Group.

    Not Applicable.

     

    Item 9.

    Notice of Dissolution of Group.

    Not Applicable.

     

    Item 10.

    Certification.

    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under §240.14a–11.


    Signatures

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

    Date: July 21, 2023

     

    HARBOURVEST PARTNERS, LLC
    By:  

    /s/ Adam Freedman

    Name:   Adam Freedman
    Title:   Chief Compliance Officer
    HARBOURVEST PARTNERS L.P.
    By: HarbourVest Partners, LLC, its General Partner
    By:  

    /s/ Adam Freedman

    Name:   Adam Freedman
    Title:   Chief Compliance Officer
    HVST-TOPE LLC
    By: HarbourVest Partners L.P., its Manager
    By: HarbourVest Partners, LLC, its General Partner
    By:  

    /s/ Adam Freedman

    Name:   Adam Freedman
    Title:   Chief Compliance Officer
    SMRS-TOPE LLC
    By: HVST-TOPE LLC, its Managing Member
    By: HarbourVest Partners L.P., its Manager
    By: HarbourVest Partners, LLC, its General Partner
    By:  

    /s/ Adam Freedman

    Name:   Adam Freedman
    Title:   Chief Compliance Officer
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      Cellarity, a life sciences company founded by Flagship Pioneering to transform the way medicines are created, announced today the appointment of Gregory J. Moore, M.D., Ph.D., to the Company's Board of Directors. As the former Corporate Vice President for Microsoft, leading global health and life sciences, Dr. Moore brings extensive experience and expertise in integrating R&D, AI and machine learning, and cloud and data technologies to positively transform companies within the health and life sciences ecosystem. "Greg is an industry leader, driving technology and life sciences innovation at the intersection of medical and large-scale computation," said Stephen Berenson, Chairman of Cellar

      6/6/23 8:00:00 AM ET
      $DNLI
      $DVA
      $EVLO
      $FHTX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
      Misc Health and Biotechnology Services
      Biotechnology: Pharmaceutical Preparations

    $EVLO
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    • JMP Securities reiterated coverage on Evelo Biosciences with a new price target

      JMP Securities reiterated coverage of Evelo Biosciences with a rating of Market Outperform and set a new price target of $41.50 from $44.00 previously

      11/2/21 7:54:09 AM ET
      $EVLO
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Evelo Biosciences upgraded by Chardan Capital Markets with a new price target

      Chardan Capital Markets upgraded Evelo Biosciences from Neutral to Buy and set a new price target of $12.00

      11/1/21 8:36:16 AM ET
      $EVLO
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • JMP Securities reiterated coverage on Evelo Biosciences with a new price target

      JMP Securities reiterated coverage of Evelo Biosciences with a rating of Market Outperform and set a new price target of $38.00 from $36.00 previously

      6/23/21 1:58:41 PM ET
      $EVLO
      Biotechnology: Pharmaceutical Preparations
      Health Care