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    SEC Form SC 13G filed by Leap Therapeutics Inc.

    11/14/24 6:07:56 AM ET
    $LPTX
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $LPTX alert in real time by email
    SC 13G 1 d878621dsc13g.htm SC 13G SC 13G

     

     

    SECURITIES AND EXCHANGE COMMISSION

    Washington, D.C. 20549

     

     

    SCHEDULE 13G

    Under the Securities Exchange Act of 1934

     

     

    Leap Therapeutics Inc.

    (Name of Issuer)

    Common Stock, par value $0.001 per share

    (Title of Class of Securities)

    52187K200

    (CUSIP Number)

    September 30, 2024

    (Date of Event Which Requires Filing of this Statement)

     

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

     

    ☒

    Rule 13d-1(b)

     

    ☐

    Rule 13d-1(c)

     

    ☐

    Rule 13d-1(d)

     

    *

    The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

    The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

     

     

     


    CUSIP No. 52187K200

     

     1   

     NAMES OF REPORTING PERSONS

     

     Balyasny Asset Management L.P.

     2  

     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

     (a) ☐  (b) ☐

     

     3  

     SEC USE ONLY

     

     4  

     CITIZENSHIP OR PLACE OF ORGANIZATION

     

     Delaware

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

       5    

     SOLE VOTING POWER

     

     3,085,104 (See Item 4)

       6   

     SHARED VOTING POWER

     

     None

       7   

     SOLE DISPOSITIVE POWER

     

     3,085,104 (See Item 4)

       8   

     SHARED DISPOSITIVE POWER

     

     None

     9   

     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

     3,085,104 (See Item 4)

    10  

     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*

     

     ☐

     

     Not Applicable

    11  

     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

     

     8.06%

    12  

     TYPE OF REPORTING PERSON*

     

     IA, PN

     

    *SEE INSTRUCTIONS BEFORE FILLING OUT.


    CUSIP No. 52187K200

     

     1   

     NAMES OF REPORTING PERSONS

     

     BAM GP LLC

     2  

     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

     (a) ☐  (b) ☐

     

     3  

     SEC USE ONLY

     

     4  

     CITIZENSHIP OR PLACE OF ORGANIZATION

     

     Delaware

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

       5    

     SOLE VOTING POWER

     

     3,085,104 (See Item 4)

       6   

     SHARED VOTING POWER

     

     None

       7   

     SOLE DISPOSITIVE POWER

     

     3,085,104 (See Item 4)

       8   

     SHARED DISPOSITIVE POWER

     

     None

     9   

     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

     3,085,104 (See Item 4)

    10  

     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*

     

     ☐

     

     Not Applicable

    11  

     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

     

     8.06%

    12  

     TYPE OF REPORTING PERSON*

     

     HC, OO

     

    *SEE INSTRUCTIONS BEFORE FILLING OUT.


    CUSIP No. 52187K200

     

     1   

     NAMES OF REPORTING PERSONS

     

     Balyasny Asset Management Holdings LP

     2  

     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

     (a) ☐  (b) ☐

     

     3  

     SEC USE ONLY

     

     4  

     CITIZENSHIP OR PLACE OF ORGANIZATION

     

     Delaware

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

       5    

     SOLE VOTING POWER

     

     3,085,104 (See Item 4)

       6   

     SHARED VOTING POWER

     

     None

       7   

     SOLE DISPOSITIVE POWER

     

     3,085,104 (See Item 4)

       8   

     SHARED DISPOSITIVE POWER

     

     None

     9   

     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

     3,085,104 (See Item 4)

    10  

     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*

     

     ☐

     

     Not Applicable

    11  

     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

     

     8.06%

    12  

     TYPE OF REPORTING PERSON*

     

     HC, PN

     

    *SEE INSTRUCTIONS BEFORE FILLING OUT.


    CUSIP No. 52187K200

     

     1   

     NAMES OF REPORTING PERSONS

     

     Dames GP LLC

     2  

     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

     (a) ☐  (b) ☐

     

     3  

     SEC USE ONLY

     

     4  

     CITIZENSHIP OR PLACE OF ORGANIZATION

     

     Delaware

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

       5    

     SOLE VOTING POWER

     

     3,085,104 (See Item 4)

       6   

     SHARED VOTING POWER

     

     None

       7   

     SOLE DISPOSITIVE POWER

     

     3,085,104 (See Item 4)

       8   

     SHARED DISPOSITIVE POWER

     

     None

     9   

     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

     3,085,104 (See Item 4)

    10  

     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*

     

     ☐

     

     Not Applicable

    11  

     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

     

     8.06%

    12  

     TYPE OF REPORTING PERSON*

     

     HC, OO

     

    *SEE INSTRUCTIONS BEFORE FILLING OUT.


    CUSIP No. 52187K200

     

     1   

     NAMES OF REPORTING PERSONS

     

     Dmitry Balyasny

     2  

     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

     (a) ☐  (b) ☐

     

     3  

     SEC USE ONLY

     

     4  

     CITIZENSHIP OR PLACE OF ORGANIZATION

     

     United States

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

       5    

     SOLE VOTING POWER

     

     3,085,104 (See Item 4)

       6   

     SHARED VOTING POWER

     

     None

       7   

     SOLE DISPOSITIVE POWER

     

     3,085,104 (See Item 4)

       8   

     SHARED DISPOSITIVE POWER

     

     None

     9   

     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

     3,085,104 (See Item 4)

    10  

     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*

     

     ☐

     

     Not Applicable

    11  

     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

     

     8.06%

    12  

     TYPE OF REPORTING PERSON*

     

     HC, IN

     

    *SEE INSTRUCTIONS BEFORE FILLING OUT.


    Item 1    (a)    Name of Issuer:
          Leap Therapeutics Inc.
       (b)    Address of Issuer’s Principal Executive Offices:
          47 Thorndike Street
          Suite B1-1
          Cambridge, MA 02141
          United States
    Item 2    (a) – (c)    This statement is filed on behalf of the following:
          (1)    Balyasny Asset Management L.P. is a Delaware limited partnership (“BAM”), with its principal business office at 444 West Lake Street, 50th Floor, Chicago, IL 60606.
          (2)    BAM GP LLC is a Delaware limited liability company (“BAM GP”), with its principal business office at 444 West Lake Street, 50th Floor, Chicago, IL 60606. BAM GP is the General Partner of BAM.
          (3)    Balyasny Asset Management Holdings LP is a Delaware limited partnership (“BAM Holdings”), with its principal business office at 444 West Lake Street, 50th Floor, Chicago, IL 60606. BAM Holdings is the Sole Member of BAM GP.
          (4)    Dames GP LLC is a Delaware limited liability company (“Dames”), with its principal business office at 444 West Lake Street, 50th Floor, Chicago, IL 60606. Dames is the General Partner of BAM Holdings.
          (5)    Dmitry Balyasny, a United States citizen whose business address is 444 West Lake Street, 50th Floor, Chicago, IL 60606. Dmitry Balyasny is the Managing Member of Dames.
       (d)    Title of Class of Securities:
          Common Stock, par value $0.001 per shares (“Shares”)
       (e)    CUSIP Number:
          52187K200


    Item 3   

    If this statement is filed pursuant to Rules 13d-1(b) or 13d-2(b) or (c), check whether the person filing is a:

     

        (a)    ☐    Broker or dealer registered under Section 15 of the Act (15 U.S.C. 78o).
        (b)    ☐    Bank as defined in Section 3(a)(6) of the Act (15 U.S.C. 78c).
      (c)    ☐    Insurance company as defined in Section 3(a)(19) of the Act (15 U.S.C. 78c).
      (d)    ☐    Investment company registered under Section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8).
      (e)    ☒    An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E);
      (f)    ☐    An employee benefit plan or endowment fund in accordance with Rule 13d-1(b)(1)(ii)(F);
      (g)    ☒    A parent holding company or control person in accordance with Rule 13d-1(b)(1)(ii)(G);
      (h)    ☐    A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C.1813);
      (i)    ☐    A church plan that is excluded from the definition of an investment company under Section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
      (j)    ☐    A non-U.S. institution in accordance with Rule 13d-1(b)(1)(ii)(J);
      (k)    ☐    Group, in accordance with Rule 13d-1(b)(1)(ii)(K).

     

    Item 4

    Ownership:

    BAM

     

      (a)

    Amount Beneficially Owned:

    By virtue of its position as the investment manager of Atlas Diversified Master Fund, Ltd. (“ADMF”), the direct holder of the 3,085,104 Shares reported herein, BAM may be deemed to exercise voting and investment power over such Shares held by ADMF and thus may be deemed to beneficially own such Shares.

     

      (b)

    Percent of Class:

    8.06%


      (c)

    Number of Shares as to which person has:

     

      (i)

    Sole power to vote or to direct vote:

    3,085,104

     

      (ii)

    Shared power to vote or to direct vote:

    None

     

      (iii)

    Sole power to dispose or direct disposition of:

    3,085,104

     

      (iv)

    Shared power to dispose or to direct disposition of:

    None

    BAM GP

     

      (b)

    Amount Beneficially Owned:

    By virtue of its position as the General Partner of BAM, BAM GP may be deemed to exercise voting and investment power over the Shares held directly by ADMF and thus may be deemed to beneficially own such Shares.

     

      (b)

    Percent of Class:

    8.06%

     

      (c)

    Number of Shares as to which person has:

     

      (i)

    Sole power to vote or to direct vote:

    3,085,104

     

      (ii)

    Shared power to vote or to direct vote:

    None

     

      (iii)

    Sole power to dispose or direct disposition of:

    3,085,104

     

      (iv)

    Shared power to dispose or to direct disposition of:

    None

    BAM Holdings


      (c)

    Amount Beneficially Owned:

    By virtue of its position as the Sole Member of BAM GP, BAM Holdings may be deemed to exercise voting and investment power over the Shares held directly by ADMF and thus may be deemed to beneficially own such Shares.

     

      (b)

    Percent of Class:

    8.06%

     

      (c)

    Number of Shares as to which person has:

     

      (i)

    Sole power to vote or to direct vote:

    3,085,104

     

      (ii)

    Shared power to vote or to direct vote:

    None

     

      (iii)

    Sole power to dispose or direct disposition of:

    3,085,104

     

      (iv)

    Shared power to dispose or to direct disposition of:

    None

    Dames

     

      (d)

    Amount Beneficially Owned:

    By virtue of its position as the General Partner of BAM Holdings, Dames may be deemed to exercise voting and investment power over the Shares held directly by ADMF and thus may be deemed to beneficially own such Shares.

     

      (b)

    Percent of Class:

    8.06%


      (c)

    Number of Shares as to which person has:

     

      (i)

    Sole power to vote or to direct vote:

    3,085,104

     

      (ii)

    Shared power to vote or to direct vote:

    None

     

      (iii)

    Sole power to dispose or direct disposition of:

    3,085,104

     

      (iv)

    Shared power to dispose or to direct disposition of:

    None

    Dmitry Balyasny

     

      (a)

    Amount Beneficially Owned:

    By virtue of his position as the Managing Member of Dames, Mr. Balyasny may be deemed to exercise voting and investment power over the Shares held directly by ADMF and thus may be deemed to beneficially own such Shares.

     

      (b)

    Percent of Class:

    8.06%

     

      (c)

    Number of Shares as to which person has:

     

      (i)

    Sole power to vote or to direct vote:

    3,085,104

     

      (ii)

    Shared power to vote or to direct vote:

    None

     

      (iii)

    Sole power to dispose or direct disposition of:

    3,085,104

     

      (iv)

    Shared power to dispose or to direct disposition of:

    None


    Item 5

    Ownership of Five Percent or Less of a Class:

    Not Applicable

     

    Item 6

    Ownership of More than Five Percent on Behalf of Another Person:

    ADMF, a Cayman Islands exempted company that is an investment management client of BAM, has the right to receive dividends from, or the proceeds from the sale of, the reported securities.

     

    Item 7

    Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company:

    Not Applicable

     

    Item 8

    Identification and Classification of Members of the Group:

    Not Applicable

     

    Item 9

    Notice of Dissolution of Group:

    Not Applicable

     

    Item 10

    Certification:

    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.


    SIGNATURE

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

    Date: November 6, 2024

     

    BALYASNY ASSET MANAGEMENT L.P.
    By:  

    /s/ Scott Schroeder

    Name:   Scott Schroeder
    Title:   Authorized Signatory
    BAM GP LLC
    By:  

    /s/ Scott Schroeder

    Name:   Scott Schroeder
    Title:   Authorized Signatory
    BALYASNY ASSET MANAGEMENT HOLDING LP
    By:  

    /s/ Scott Schroeder

    Name:   Scott Schroeder
    Title:   Authorized Signatory
    DAMES GP LLC
    By:  

    /s/ Scott Schroeder

    Name:   Scott Schroeder
    Title:   Authorized Signatory
    DMITRY BALYASNY
    By:  

    /s/ Dmitry Balyasny

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      35% objective response rate (ORR) in second-line colorectal cancer (CRC) patients treated with sirexatamab (DKN-01) plus bevacizumab and chemotherapy, compared to 23% ORR in the control arm DKK1 levels highly correlated with clinical activity in CRC population ORR benefit with sirexatamab observed across multiple potential Phase 3 CRC populations Preparations will begin for a registrational Phase 3 study in second-line CRC patients DisTinGuish Part C study in gastric cancer demonstrates activity in biomarker populations, but not the signal necessary to advance into Phase 3 Leap to host a conference call to present clinical data today, January 28, 2025, at 8:00 a.m. ET CAMBRIDGE, Mass., Jan.

      1/28/25 7:00:00 AM ET
      $LPTX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $LPTX
    Large Ownership Changes

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    • SEC Form SC 13G filed by Leap Therapeutics Inc.

      SC 13G - LEAP THERAPEUTICS, INC. (0001509745) (Subject)

      11/14/24 6:07:56 AM ET
      $LPTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G filed by Leap Therapeutics Inc.

      SC 13G - LEAP THERAPEUTICS, INC. (0001509745) (Subject)

      4/25/24 8:39:23 PM ET
      $LPTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G filed by Leap Therapeutics Inc.

      SC 13G - LEAP THERAPEUTICS, INC. (0001509745) (Subject)

      4/19/24 4:31:26 PM ET
      $LPTX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $LPTX
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

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    • Leap Therapeutics downgraded by H.C. Wainwright

      H.C. Wainwright downgraded Leap Therapeutics from Buy to Neutral

      1/29/25 7:15:39 AM ET
      $LPTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Leap Therapeutics downgraded by Robert W. Baird with a new price target

      Robert W. Baird downgraded Leap Therapeutics from Outperform to Neutral and set a new price target of $1.25 from $9.00 previously

      1/29/25 7:15:19 AM ET
      $LPTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Rodman & Renshaw initiated coverage on Leap Therapeutics with a new price target

      Rodman & Renshaw initiated coverage of Leap Therapeutics with a rating of Buy and set a new price target of $8.00

      6/28/24 8:18:39 AM ET
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      Biotechnology: Pharmaceutical Preparations
      Health Care

    $LPTX
    SEC Filings

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    • Leap Therapeutics Inc. filed SEC Form 8-K: Results of Operations and Financial Condition, Financial Statements and Exhibits

      8-K - LEAP THERAPEUTICS, INC. (0001509745) (Filer)

      5/13/25 7:10:27 AM ET
      $LPTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 10-Q filed by Leap Therapeutics Inc.

      10-Q - LEAP THERAPEUTICS, INC. (0001509745) (Filer)

      5/13/25 6:51:44 AM ET
      $LPTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form DEFA14A filed by Leap Therapeutics Inc.

      DEFA14A - LEAP THERAPEUTICS, INC. (0001509745) (Filer)

      4/25/25 8:54:12 PM ET
      $LPTX
      Biotechnology: Pharmaceutical Preparations
      Health Care