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    SEC Form SC 13G/A filed

    2/12/21 4:31:01 PM ET
    $TARA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $TARA alert in real time by email
    SC 13G/A 1 d263664dsc13ga.htm SC 13G/A SC 13G/A

     

     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    Washington, D.C. 20549

     

     

    SCHEDULE 13G

    Under the Securities Exchange Act of 1934

    (Amendment No. 1)*

     

     

    PROTARA THERAPEUTICS, INC.

    (Name of Issuer)

    Common Stock, par value $0.001 per share

    (Title of Class of Securities)

    74365U107

    (CUSIP Number)

    December 31, 2020

    (Date of Event which Requires Filing of this Statement)

     

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

    ☐ Rule 13d-1(b)

    ☒ Rule 13d-1(c)

    ☐ Rule 13d-1(d)

     

    *

    The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

    The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934, as amended (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

    Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications:

    Evan K. Hall, Esq.

    Haynes and Boone, LLP

    2323 Victory Avenue, Suite 700

    Dallas, Texas 75219-7673

    (214) 651-5000

     

     

     


    SCHEDULE 13G

     

    CUSIP No. 74365U107

     

         

     

      1   

    Names of Reporting Persons

     

    Ikarian Capital, LLC

      2  

    Check the appropriate box if a member of a Group (see instructions)

    (a)  ☐        (b)  ☒

     

      3  

    Sec Use Only

     

        

      4  

    Citizenship or Place of Organization

     

    Delaware

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person

    With:

       5    

    Sole Voting Power

     

    0

       6   

    Shared Voting Power

     

    649,542

       7   

    Sole Dispositive Power

     

    0

       8   

    Shared Dispositive Power

     

    649,542

      9  

    Aggregate Amount Beneficially Owned by Each Reporting Person

     

    649,542

    10  

    Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

     

    ☐

    11  

    Percent of class represented by amount in row (9)

     

    5.8% (1)

    12  

    Type of Reporting Person (See Instructions)

     

    IA

     

    (1)

    Based upon 11,211,840 shares of Common Stock, par value $0.001 per share, outstanding as of December 7, 2020, as disclosed in the Issuer’s Prospectus, that was filed on December 9, 2020, by the Issuer with the U.S. Securities and Exchange Commission.


    SCHEDULE 13G

     

    CUSIP No. 74365U107

     

         

     

      1   

    Names of Reporting Persons

     

    Ikarian Healthcare Master Fund, L.P.

      2  

    Check the appropriate box if a member of a Group (see instructions)

    (a)  ☐        (b)  ☒

     

      3  

    Sec Use Only

     

        

      4  

    Citizenship or Place of Organization

     

    Cayman Islands

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person

    With:

       5    

    Sole Voting Power

     

    0

       6   

    Shared Voting Power

     

    530,427

       7   

    Sole Dispositive Power

     

    0

       8   

    Shared Dispositive Power

     

    530,427

      9  

    Aggregate Amount Beneficially Owned by Each Reporting Person

     

    530,427

    10  

    Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

     

    ☐

    11  

    Percent of class represented by amount in row (9)

     

    4.7% (1)

    12  

    Type of Reporting Person (See Instructions)

     

    PN

     

    (1)

    Based upon 11,211,840 shares of Common Stock, par value $0.001 per share, outstanding as of December 7, 2020, as disclosed in the Issuer’s Prospectus, that was filed on December 9, 2020, by the Issuer with the U.S. Securities and Exchange Commission.


    SCHEDULE 13G

     

    CUSIP No. 74365U107

     

         

     

      1   

    Names of Reporting Persons

     

    Ikarian Healthcare Fund GP, L.P.

      2  

    Check the appropriate box if a member of a Group (see instructions)

    (a)  ☐        (b)  ☒

     

      3  

    Sec Use Only

     

        

      4  

    Citizenship or Place of Organization

     

    Delaware

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person

    With:

       5    

    Sole Voting Power

     

    0

       6   

    Shared Voting Power

     

    530,427

       7   

    Sole Dispositive Power

     

    0

       8   

    Shared Dispositive Power

     

    530,427

      9  

    Aggregate Amount Beneficially Owned by Each Reporting Person

     

    530,427

    10  

    Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

     

    ☐

    11  

    Percent of class represented by amount in row (9)

     

    4.7% (1)

    12  

    Type of Reporting Person (See Instructions)

     

    PN

     

    (1)

    Based upon 11,211,840 shares of Common Stock, par value $0.001 per share, outstanding as of December 7, 2020, as disclosed in the Issuer’s Prospectus, that was filed on December 9, 2020, by the Issuer with the U.S. Securities and Exchange Commission.


    SCHEDULE 13G

     

    CUSIP No. 74365U107

     

         

     

      1   

    Names of Reporting Persons

     

    Chart Westcott

      2  

    Check the appropriate box if a member of a Group (see instructions)

    (a)  ☐        (b)  ☒

     

      3  

    Sec Use Only

     

        

      4  

    Citizenship or Place of Organization

     

    United States

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person

    With:

       5    

    Sole Voting Power

     

    0

       6   

    Shared Voting Power

     

    649,542

       7   

    Sole Dispositive Power

     

    0

       8   

    Shared Dispositive Power

     

    649,542

      9  

    Aggregate Amount Beneficially Owned by Each Reporting Person

     

    649,542

    10  

    Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

     

    ☐

    11  

    Percent of class represented by amount in row (9)

     

    5.8% (1)

    12  

    Type of Reporting Person (See Instructions)

     

    IN; HC

     

    (1)

    Based upon 11,211,840 shares of Common Stock, par value $0.001 per share, outstanding as of December 7, 2020, as disclosed in the Issuer’s Prospectus, that was filed on December 9, 2020, by the Issuer with the U.S. Securities and Exchange Commission.


    SCHEDULE 13G

     

    CUSIP No. 74365U107

     

         

     

      1   

    Names of Reporting Persons

     

    Neil Shahrestani

      2  

    Check the appropriate box if a member of a Group (see instructions)

    (a)  ☐        (b)  ☒

     

      3  

    Sec Use Only

     

        

      4  

    Citizenship or Place of Organization

     

    United States of America

    Number of

    Shares

    Beneficially

    Owned by

    Each

    Reporting

    Person

    With:

       5    

    Sole Voting Power

     

    0

       6   

    Shared Voting Power

     

    649,542

       7   

    Sole Dispositive Power

     

    0

       8   

    Shared Dispositive Power

     

    649,542

      9  

    Aggregate Amount Beneficially Owned by Each Reporting Person

     

    649,542

    10  

    Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

     

    ☐

    11  

    Percent of class represented by amount in row (9)

     

    5.8% (1)

    12  

    Type of Reporting Person (See Instructions)

     

    IN; HC

     

    (1)

    Based upon 11,211,840 shares of Common Stock, par value $0.001 per share, outstanding as of December 7, 2020, as disclosed in the Issuer’s Prospectus, that was filed on December 9, 2020, by the Issuer with the U.S. Securities and Exchange Commission.


    Item 1.

     

      (a)

    Name of Issuer:

    PROTARA THERAPEUTICS, INC.

     

      (b)

    Address of Issuer’s Principal Executive Offices:

    1 Little West 12th Street, New York, New York 10014

     

    Item 2.

     

    (a)

    Name of Person Filing:

    This statement is jointly filed by and on behalf of each of Ikarian Capital, LLC, a Delaware limited liability company (“Ikarian Capital”), Ikarian Healthcare Master Fund, L.P, a Cayman Islands exempted limited partnership (the “Fund”), Ikarian Healthcare Fund GP, L.P., a Delaware limited partnership (“Ikarian GP”), Chart Westcott and Neil Shahrestani (collectively referred herein as the “Reporting Persons”). Ikarian Capital is the investment manager of, and may be deemed to indirectly beneficially own securities owned by, the Fund. Ikarian GP is the general partner of, and may be deemed to indirectly beneficially own securities owned by, the Fund. Ikarian Capital is also the general partner of, and may be deemed to indirectly beneficially own, securities beneficially owned by Ikarian GP. Ikarian Capital is a sub-advisor for certain separate managed accounts (collectively, the “Managed Accounts”) and may be deemed to indirectly beneficially own securities owned by the Managed Accounts. Ikarian Capital is ultimately owned and controlled by Chart Westcott Living Trust, of which Mr. Westcott serves as the sole trustee (the “Trust”), and Mr. Shahrestani. Accordingly, each of Mr. Westcott, as sole trustee of the Trust, and Mr. Shahrestani may be deemed to indirectly beneficially own securities beneficially owned by, Ikarian Capital. The Fund and the Managed Accounts are the record and direct beneficial owners of the securities covered by this statement. The Fund disclaims beneficial ownership of the shares held by the Managed Accounts.

    Each Reporting Person declares that neither the filing of this statement nor anything herein shall be construed as an admission that such person is, for the purposes of Section 13(d) or 13(g) of the Act or any other purpose, the beneficial owner of any securities covered by this statement.

    Each Reporting Person may be deemed to be a member of a group with respect to the issuer or securities of the issuer for the purpose of Section 13(d) or 13(g) of the Act. Each of the Reporting Persons declares that neither the filing of this statement nor anything herein shall be construed as an admission that such person is, for the purpose of Section 13(d) or 13(g) of the Act or any other purpose, (i) acting (or has agreed or is agreeing to act together with any other person) as a partnership, limited partnership, syndicate, or other group for the purpose of acquiring, holding, or disposing of securities of the issuer or otherwise with respect to the issuer or any securities of the issuer or (ii) a member of any group with respect to the issuer or any securities of the issuer.

     

    (b)

    Address of Principal Business Office or, if None, Residence:

    The address of the principal business office of each of the Reporting Persons is c/o Ikarian Capital, LLC, 100 Crescent Court, Suite 1620, Dallas, Texas 75201.


    (c)

    Citizenship:

    See Item 4 on the cover page(s) hereto.

     

    (d)

    Title and Class of Securities:

    Common Stock, par value $0.001 per share

     

    (e)

    CUSIP No.:

    74365U107    

     

    Item 3.

    If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

     

    (a)    ☐    Broker or dealer registered under Section 15 of the Act;
    (b)    ☐    Bank as defined in Section 3(a)(6) of the Act;
    (c)    ☐    Insurance company as defined in Section 3(a)(19) of the Act;
    (d)    ☐    Investment company registered under Section 8 of the Investment Company Act of 1940;
    (e)    ☐    An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E);
    (f)    ☐    An employee benefit plan or endowment fund in accordance with Rule 13d-1(b)(1)(ii)(F);
    (g)    ☐    A parent holding company or control person in accordance with Rule 13d-1(b)(1)(ii)(G);
    (h)    ☐    A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
    (i)    ☐    A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940;
    (j)    ☐    A non-U.S. institution in accordance with Rule 240.13d-1(b)(1)(ii)(J);
    (k)    ☐    Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K). If filing as a non-U.S. institution in accordance with Rule 240.13d-1(b)(1)(ii)(J), please specify the type of institution:                    

     

    Item 4.

    Ownership

     

    (a)

    Amount Beneficially Owned as of December 31, 2020: See Item 9 on the cover pages(s) hereto.

     

    (b)

    Percent of Class as of December 31, 2020: See Item 11 on the cover page(s) hereto.

     

    (c)

    As of December 31, 2020, number of shares as to which such person has:

     

      (i)

    Sole power to vote or to direct the vote: See Item 5 on the cover pages hereto.

     

      (ii)

    Shared power to vote or to direct the vote: See Item 6 on the cover pages hereto.


      (iii)

    Sole power to dispose or to direct the disposition of: See Item 7 on the cover pages hereto.

     

      (iv)

    Shared power to dispose or to direct the disposition of: See Item 8 on the cover pages hereto.

     

    Item 5.

    Ownership of Five Percent or Less of a Class.

    If this statement is being filed to report the fact that as of the date hereof the Reporting Persons have ceased to be the beneficial owners of more than five percent of the class of securities, check the following  ☐.

     

    Item 6.

    Ownership of more than Five Percent on Behalf of Another Person.

    The information set forth in Item 2(a) is incorporated by reference herein.

     

    Item 7.

    Identification and classification of the subsidiary which acquired the security being reported on by the parent holding company or control person.

    Not applicable.

     

    Item 8.

    Identification and classification of members of the group.

    Not applicable.

     

    Item 9.

    Notice of Dissolution of Group.

    Not applicable.

     

    Item 10.

    Certifications.

    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect other than activities solely in connection with a nomination under § 240.14a-11.


    SIGNATURE

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

    Dated: February 12, 2021

     

    IKARIAN CAPITAL, LLC
    By:   Chart Westcott Living Trust
    Its:   Manager
    By:  

    /s/ Chart Westcott

      Chart Westcott, Trustee
    IKARIAN HEALTHCARE MASTER FUND, L.P.
    By:   Ikarian Healthcare Fund GP, L.P.
    Its:   General Partner
    By:   Ikarian Capital, LLC
    Its:   General Partner
    By:   Chart Westcott Living Trust
    Its:   Manager
    By:  

    /s/ Chart Westcott

      Chart Westcott, Trustee
    IKARIAN HEALTHCARE FUND GP, L.P.
    By:   Ikarian Capital, LLC
    Its:   General Partner
    By:   Chart Westcott Living Trust
    Its:   Manager
    By:  

    /s/ Chart Westcott

      Chart Westcott, Trustee
    CHART WESTCOTT LIVING TRUST
    By:  

    /s/ Chart Westcott

      Chart Westcott, Trustee
    NEIL SHAHRESTANI

    /s/ Neil Shahrestani


    EXHIBIT INDEX

     

    Exhibit

      

    Description of Exhibit

    99.1    Joint Filing Agreement (incorporated herein by reference to Exhibit 99.1 to the Schedule 13G filed on February 21, 2020, by the Reporting Persons with the Securities and Exchange Commission).
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    Protara Therapeutics Announces Appointment of William Conkling as Chief Commercial Officer

    NEW YORK, June 02, 2025 (GLOBE NEWSWIRE) -- Protara Therapeutics, Inc. (NASDAQ:TARA), a clinical-stage company developing transformative therapies for the treatment of cancer and rare diseases, today announced the appointment of William "Bill" Conkling as Chief Commercial Officer. He brings more than two decades of experience developing and commercializing novel cancer and rare disease therapeutics to Protara. "It is a pleasure to welcome Bill, a deeply experienced and proven commercial leader," said Jesse Shefferman, Chief Executive Officer of Protara Therapeutics. "With an impressive track record building commercial organizations and successfully launching oncology and rare disease prod

    6/2/25 4:04:01 PM ET
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    Protara Therapeutics Announces Updated Interim Data from Phase 2 ADVANCED-2 Trial of TARA-002 in BCG-Naïve NMIBC Patients

    TARA-002 demonstrates 72% complete response rate at any time in BCG-Naïve patientsTARA-002 demonstrates a 69% complete response rate at the 6-month landmark and a 50% complete response rate at the 12-month landmark in BCG-Naïve patientsFavorable safety and tolerability profile observed with no Grade 3 or greater treatment-related adverse events reportedCompany obtained written feedback from FDA on registrational path forward for TARA-002 in BCG-Naïve patientsCompany remains on track to report interim results from approximately 25 six-month evaluable BCG-Unresponsive patients in the registrational cohort of the ADVANCED-2 trial in Q1 2026 Company expects to complete enrollment of the BCG-Unre

    12/3/25 8:00:00 AM ET
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    Biotechnology: Biological Products (No Diagnostic Substances)
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    Protara Therapeutics to Host Conference Call and Webcast to Review New Interim Data from Phase 2 ADVANCED-2 Trial of TARA-002 in BCG-Naïve NMIBC Patients on Wednesday, December 3, 2025

    NEW YORK, Dec. 01, 2025 (GLOBE NEWSWIRE) -- Protara Therapeutics, Inc. (NASDAQ:TARA), a clinical-stage company developing transformative therapies for the treatment of cancer and rare diseases, today announced that it will host a conference call and live webcast at 8:30 am ET on Wednesday, December 3, 2025, to review new data from an interim analysis of the ongoing Phase 2 open-label ADVANCED-2 trial of TARA-002 in BCG-Naïve patients with non-muscle invasive bladder cancer (NMIBC). The data will be featured during a poster session at the 26th Annual Meeting of the Society of Urologic Oncology (SUO). The Company will also provide an update on feedback from the U.S. Food and Drug Administrat

    12/1/25 4:15:00 PM ET
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    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Protara Therapeutics Announces Positive Interim Results Demonstrating Robust Responses in the Ongoing Phase 2 STARBORN-1 Trial of TARA-002 in Pediatric Patients with Lymphatic Malformations

    80% of patients that completed treatment and 100% of patients that completed the eight-week response assessment achieved clinical successClinical success achieved with one or two doses of TARA-002 in 88% of patients TARA-002 demonstrated favorable safety and tolerability profile with no serious adverse events reportedCompany to host conference call and webcast featuring Key Opinion Leader Dr. Jesse Jones at 8:30 a.m. ET NEW YORK, Nov. 19, 2025 (GLOBE NEWSWIRE) -- Protara Therapeutics, Inc. (NASDAQ:TARA), a clinical-stage company developing transformative therapies for the treatment of cancer and rare diseases, today announced positive interim results from its ongoing Phase 2 open-label S

    11/19/25 8:00:00 AM ET
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    Biotechnology: Biological Products (No Diagnostic Substances)
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    SEC Form SC 13G filed by Protara Therapeutics Inc.

    SC 13G - Protara Therapeutics, Inc. (0001359931) (Subject)

    12/17/24 4:02:03 PM ET
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    Biotechnology: Biological Products (No Diagnostic Substances)
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    SEC Form SC 13G filed by Protara Therapeutics Inc.

    SC 13G - Protara Therapeutics, Inc. (0001359931) (Subject)

    11/18/24 6:01:42 AM ET
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    Biotechnology: Biological Products (No Diagnostic Substances)
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    SEC Form SC 13G filed by Protara Therapeutics Inc.

    SC 13G - Protara Therapeutics, Inc. (0001359931) (Subject)

    11/14/24 1:00:40 PM ET
    $TARA
    Biotechnology: Biological Products (No Diagnostic Substances)
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