• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
PublishGo to App
    Quantisnow Logo

    © 2026 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlertsPublish with Us
    Company
    AboutQuantisnow PlusContactJobsAI superconnector for talent & startupsNEWLLM Arena
    Legal
    Terms of usePrivacy policyCookie policy

    SEC Form SC 13G/A filed by Adaptimmune Therapeutics plc (Amendment)

    2/14/23 4:06:46 PM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $ADAP alert in real time by email
    SC 13G/A 1 tm235475d1_sc13g.htm SC 13G/A

     

     

     
    UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C.  20549
     
    SCHEDULE 13G
    (Rule 13d-102)
     
    Information Statement Pursuant to Rules 13d-1 and 13d-2
    Under the Securities Exchange Act of 1934
    (Amendment No. 1)*
     
      Adaptimmune Therapeutics PLC  
    (Name of Issuer)
     
      Ordinary shares, in the form of American Depositary Shares**  
    (Title of Class of Securities)
     
      00653A107  
      (CUSIP Number)  
         
      December 31, 2022  
      (Date of Event Which Requires Filing of the Statement)  

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

     

    ¨Rule 13d-1(b)
    xRule 13d-1(c)
    ¨Rule 13d-1(d)

     

    * The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

     

    ** Each American Depository Share (“ADS”) represents 6 Ordinary Shares, par value £0.001 per share.

     

    The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

     

     

     

     

     

     

    CUSIP No. 00653A107 13G Page 2 of 10 Pages

     

     

    1.

     

    NAME OF REPORTING PERSON

     

    PFM Health Sciences, LP

     

    2.

     

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a)       ¨

     

    (b)       x

     

    3.

     

    SEC USE ONLY

     

     

    4.

     

     

    CITIZENSHIP OR PLACE OF ORGANIZATION

    Delaware

     

     

    NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

     

     

    5.

     

    SOLE VOTING POWER

    0

     

    6.

     

    SHARED VOTING POWER 

     

    29,061,060 ordinary shares1 

     

    7.

     

    SOLE DISPOSITIVE POWER

    0

     

    8.

     

     

    SHARED DISPOSITIVE POWER

    See Row 6 above

     

    9.

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

    See Row 6 above

     

    10.

     

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES                                          ¨

     

     

    11.

     

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

     

    3.0%2

     

    12.

     

     

    TYPE OF REPORTING PERSON

    IA; PN

           

     

     

    1Includes 29,061,060 ordinary shares of the issuer that are represented by 4,843,510 American Depositary Shares (“ADS”) directly held by the Funds. Each ADS represents 6 ordinary shares of the issuer.

     

    2The percentages reported in this Schedule 13G are based upon 982,974,108 ordinary shares outstanding as of November 7, 2022 (according to the issuer’s Form 10-Q filed with the Securities and Exchange Commission on November 8, 2022).

     

     

     

     

    CUSIP No. 00653A107 13G Page 3 of 10 Pages

     

     

    1.

     

    NAME OF REPORTING PERSON

     

    PFM Health Sciences GP, LLC

     

    2.

     

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a)       ¨

     

    (b)       x

     

    3.

     

    SEC USE ONLY

     

     

    4.

     

     

    CITIZENSHIP OR PLACE OF ORGANIZATION

    Delaware

     

     

    NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

     

     

    5.

     

    SOLE VOTING POWER

    0

     

    6.

     

    SHARED VOTING POWER

     

    29,061,060 ordinary shares 

     

    7.

     

    SOLE DISPOSITIVE POWER

    0

     

    8.

     

     

    SHARED DISPOSITIVE POWER

    See Row 6 above

     

    9.

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

    See Row 6 above

     

    10.

     

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES                                                ¨

     

     

    11.

     

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

     

    3.0%

     

    12.

     

     

    TYPE OF REPORTING PERSON

    OO

           

     

     

     

     

    CUSIP No. 00653A107 13G Page 4 of 10 Pages

     

     

    1.

     

    NAME OF REPORTING PERSON

     

    Partner Asset Management, LLC

     

    2.

     

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a)       ¨

     

    (b)       x

     

    3.

     

    SEC USE ONLY

     

     

    4.

     

     

    CITIZENSHIP OR PLACE OF ORGANIZATION

    Delaware

     

     

    NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

     

     

    5.

     

    SOLE VOTING POWER

    0

     

    6.

     

    SHARED VOTING POWER

     

    29,061,060 ordinary shares 

     

    7.

     

    SOLE DISPOSITIVE POWER

    0

     

    8.

     

     

    SHARED DISPOSITIVE POWER

    See Row 6 above

     

    9.

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

    See Row 6 above

     

    10.

     

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES                                          ¨

     

     

    11.

     

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

     

    3.0%

     

    12.

     

     

    TYPE OF REPORTING PERSON

    OO

           

     

     

     

     

    CUSIP No. 00653A107 13G Page 5 of 10 Pages

     

     

    1.

     

    NAME OF REPORTING PERSON

     

    Brian D. Grossman

     

    2.

     

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a)       ¨

     

    (b)       x

     

    3.

     

    SEC USE ONLY

     

     

    4.

     

     

    CITIZENSHIP OR PLACE OF ORGANIZATION

    U.S. Citizen

     

     

    NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

     

     

    5.

     

    SOLE VOTING POWER

    0

     

    6.

     

    SHARED VOTING POWER

     

    29,061,060 ordinary shares 

     

    7.

     

    SOLE DISPOSITIVE POWER

    0

     

    8.

     

     

    SHARED DISPOSITIVE POWER

    See Row 6 above

     

    9.

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

    See Row 6 above

     

    10.

     

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES                                                 ¨

     

     

    11.

     

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

     

    3.0%

     

    12.

     

     

    TYPE OF REPORTING PERSON

    IN

           

     

     

     

     

    CUSIP No. 00653A107 13G Page 6 of 10 Pages

     

    Item 1(a)Name of Issuer

    Adaptimmune Therapeutics PLC

     

    Item 1(b) Address of Issuer’s Principal Executive Offices

    60 Jubilee Avenue, Milton Park, Abingdon, Oxfordshire, OX14 4RX, United Kingdom

     

    Item 2(a)Name of Person Filing
    This Schedule 13G is being jointly filed by PFM Health Sciences, LP (“PFM”), PFM Health Sciences GP, LLC (“PFM-GP”), Partner Asset Management, LLC (“PAM”), and Brian D. Grossman (“Grossman” and, collectively with PFM, PFM-GP, and PAM, the “Reporting Persons”) with respect to ordinary shares of the above-named issuer owned by PFM Biotech Opportunities LP, a Delaware limited partnership (“BO”).

     

    PFM is the investment advisor for BO. PAM is the general partner of BO. PFM-GP is the general partner of PFM and the manager of PAM. Grossman is the sole member of PFM-GP.

     

    The filing of this statement shall not be construed as an admission that any of the Reporting Persons is the beneficial owner of any securities covered by the statement other than the securities actually owned by such person (if any).

     

    Item 2(b)Address or Principal Business Office or, if none, Residence
    The address of the principal business office of each of the Reporting Persons is c/o PFM Health Sciences, LP, 475 Sansome Street, Suite 1720, San Francisco, California 94111.

     

    Item 2(c)Citizenship
    PFM is organized as a limited partnership under the laws of the State of Delaware. Each of PFM-GP and PAM is organized as a limited liability company under the laws of the State of Delaware. Grossman is a U.S. citizen.

     

    Item 2(d) Title of Class of Securities

    Ordinary shares, par value £0.001 per share

     

    Item 2(e) CUSIP Number
    00653A107

     

     

     

     

    CUSIP No. 00653A107 13G Page 7 of 10 Pages

     

    Item 3If this statement is filed pursuant to Rules 13d-1(b), or 13d-2(b) or (c), check whether the person filing is a:

      

    (a)¨ Broker or dealer registered under Section 15 of the Exchange Act;

     

    (b)¨ Bank as defined in Section 3(a)(6) of the Exchange Act;

     

    (c)¨ Insurance company as defined in Section 3(a)(19) of the Exchange Act;

     

    (d)¨ Investment company registered under Section 8 of the Investment Company Act;

     

    (e)¨ An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E);

     

    (f)¨ An employee benefit plan or endowment fund in accordance with Rule 13d-1(b)(1)(ii)(F);

     

    (g)¨ A parent holding company or control person in accordance with Rule 13d-1(b)(1)(ii)(G);

     

    (h)¨ A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act;

     

    (i)¨ A church plan that is excluded from the definition of an investment company under Section 3(c)(14) of the Investment Company Act;

     

    (j)¨ A non-U.S. institution in accordance with Rule 13d-1(b)(1)(ii)(J);

     

    (k)¨ Group, in accordance with Rule 13d-1(b)(1)(ii)(K).

     

    If filing as a non-U.S. institution in accordance with Rule 13d-1(b)(1)(ii)(J), please specify the type of institution: ____________.

      

     

     

     

    CUSIP No. 00653A107 13G Page 8 of 10 Pages

     

    Item 4 Ownership

     

    A.PFM Health Sciences, LP, PFM Health Sciences GP, LLC and Partner Asset Management, LLC

     

    (a)PFM, PFM-GP and PAM may be deemed to beneficially own 29,061,060 ordinary shares.

     

    (b)The number of shares PFM, PFM-GP and PAM may be deemed to beneficially own constitutes approximately 3.0% of the ordinary shares outstanding.

     

    (c)Number of shares as to which such person has:

     

    (i)sole power to vote or to direct the vote: 0

     

    (ii)shared power to vote or to direct the vote: 29,061,060

     

    (iii)sole power to dispose or to direct the disposition of: 0

     

    (iv)shared power to dispose or to direct the disposition of: 29,061,060

     

    B.Brian D. Grossman

     

    (a)Grossman may be deemed to beneficially own 29,061,060 ordinary shares.

     

    (b)The number of shares Grossman may be deemed to beneficially own constitutes approximately 3.0% of the ordinary shares outstanding.

     

    (c)Number of shares as to which such person has:

     

    (i)sole power to vote or to direct the vote: 0

     

    (ii)shared power to vote or to direct the vote: 29,061,060

     

    (iii)sole power to dispose or to direct the disposition of: 0

     

    (iv)shared power to dispose or to direct the disposition of: 29,061,060

     

    Item 5Ownership of Five Percent or Less of a Class
    If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than 5 percent of the class of securities, check the following x.

     

    Item 6Ownership of More than Five Percent on Behalf of Another Person

    Not Applicable

     

    Item 7Identification and Classification of the Subsidiary which Acquired the Security Being Reported on by the Parent Holding Company

    See Item 2 above

     

     

     

     

    CUSIP No. 00653A107 13G Page 9 of 10 Pages

     

    Item 8Identification and Classification of Members of the Group

    Not Applicable

     

    Item 9Notice of Dissolution of Group

    Not Applicable

     

    Item 10Certification
    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.

     

     

     

     

    After reasonable inquiry and to the best of its knowledge and belief, the undersigned certify that the information set forth in this statement is true, complete and correct.

     

    Dated this 14th day of February, 2023.

     

    PFM HEALTH SCIENCES, LP   PFM HEALTH SCIENCES GP, LLC
         
    By: PFM Health Sciences GP, LLC,   By: /s/ Darin Sadow
      its general partner     Darin Sadow, Authorized Signatory
         
    By: /s/ Darin Sadow    
      Darin Sadow, Authorized Signatory    

     

    PARTNER ASSET MANAGEMENT, LLC   BRIAN D. GROSSMAN
         
    By:

    PFM Health Sciences GP, LLC,

      By: /s/ Darin Sadow
      its manager     Darin Sadow, attorney-in-fact*
         
    By: /s/ Darin Sadow  
      Darin Sadow, Authorized Signatory    

     

     

    *Darin Sadow is signing on behalf of Brian Grossman as attorney-in-fact pursuant to a power of attorney dated August 4, 2011, and incorporated by reference herein. The power of attorney was filed as an attachment to a filing by certain of the Reporting Persons on Schedule 13G for K-V Pharmaceutical Company on August 5, 2011.

     

     

     

    Get the next $ADAP alert in real time by email

    Crush Q1 2026 with the Best AI Superconnector

    Stay ahead of the competition with Standout.work - your AI-powered talent-to-startup matching platform.

    AI-Powered Inbox
    Context-aware email replies
    Strategic Decision Support
    Get Started with Standout.work

    Recent Analyst Ratings for
    $ADAP

    DatePrice TargetRatingAnalyst
    7/29/2025Buy → Neutral
    H.C. Wainwright
    6/26/2025$0.50Outperform → Neutral
    Mizuho
    7/30/2024$4.00Buy
    H.C. Wainwright
    5/30/2024$3.15Sector Outperform
    Scotiabank
    3/24/2023$3.60Buy
    Bryan Garnier
    1/3/2023$5.00Neutral → Buy
    Guggenheim
    11/9/2022$9.00Neutral → Buy
    Mizuho
    9/22/2021$6.00 → $7.00Equal-Weight
    Wells Fargo
    More analyst ratings

    $ADAP
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    View All

    Adaptimmune Therapeutics downgraded by H.C. Wainwright

    H.C. Wainwright downgraded Adaptimmune Therapeutics from Buy to Neutral

    7/29/25 7:36:15 AM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Adaptimmune Therapeutics downgraded by Mizuho with a new price target

    Mizuho downgraded Adaptimmune Therapeutics from Outperform to Neutral and set a new price target of $0.50

    6/26/25 7:50:31 AM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    H.C. Wainwright initiated coverage on Adaptimmune Therapeutics with a new price target

    H.C. Wainwright initiated coverage of Adaptimmune Therapeutics with a rating of Buy and set a new price target of $4.00

    7/30/24 6:31:41 AM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $ADAP
    Press Releases

    Fastest customizable press release news feed in the world

    View All

    Adaptimmune Announces Delisting from Nasdaq

    Philadelphia, Pennsylvania and Oxford, United Kingdom--(Newsfile Corp. - October 20, 2025) - Adaptimmune Therapeutics plc (NASDAQ:ADAP) ("Adaptimmune" or the "Company") today announced that the Company's Board of Directors (the "Board") has determined to initiate the delisting of its American Depositary Shares ("ADSs"), each representing six ordinary shares, from The Nasdaq Capital Market ("Nasdaq") and deregistration under Section 12(b) of the Securities Exchange Act of 1934, as amended (the "Exchange Act"). Adrian Rawcliffe, Adaptimmune's Chief Executive Officer: "As we noted previously, the transaction with USWM CT, LLC, a subsidiary of US WorldMeds Partners, LLC (collectively, "US WorldM

    10/20/25 7:40:00 AM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Adaptimmune Reports Q2 Financial Results and Provides Business Update

    Q2 Tecelra sales of $11.1m with 16 patients invoiced represents >150% growth vs Q1 2025Entered into a definitive agreement for the sale of TECELRA, lete-cel, afami-cel, and uza-cel cell therapies to US WorldMeds for $55 million upfront with up to $30 million in future milestone paymentsFollowing the transaction, Adaptimmune has repaid its debt and is restructuring to maximize value from remaining assets, including PRAME and CD70 directed T-cell therapiesPhiladelphia, Pennsylvania and Oxford, United Kingdom--(Newsfile Corp. - August 13, 2025) - Adaptimmune Therapeutics plc (NASDAQ:ADAP) today reported financial results and provided a business update for the second quarter ended June 30, 2025.

    8/13/25 7:30:00 AM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Adaptimmune Announces Entry into Definitive Agreement for Sale of TECELRA, lete-cel, afami-cel and uza-cel Cell Therapies to US WorldMeds

    Tecelra will continue to be available to patients without interruption US WorldMeds plans to bring lete-cel to market and will continue development of uza-cel in collaboration with GalapagosPurchase price is $55m in cash to be paid upon consummation of the sale with up to $30m in potential future payments upon achievement of certain milestonesAdaptimmune will retain rights to its preclinical assets including PRAME, CD70, and its allogeneic program Adaptimmune will restructure to support the transition of these therapies to US WorldMeds and to maximize value from its remaining assetsAdaptimmune's Board of Directors determined this transaction is in the best interest of all stakeholders follow

    7/28/25 7:30:00 AM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $ADAP
    SEC Filings

    View All

    SEC Form EFFECT filed by Adaptimmune Therapeutics plc

    EFFECT - Adaptimmune Therapeutics PLC (0001621227) (Filer)

    11/17/25 12:15:22 AM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form 424B3 filed by Adaptimmune Therapeutics plc

    424B3 - Adaptimmune Therapeutics PLC (0001621227) (Filer)

    11/13/25 8:05:39 AM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form 15-12G filed by Adaptimmune Therapeutics plc

    15-12G - Adaptimmune Therapeutics PLC (0001621227) (Filer)

    11/13/25 7:30:13 AM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $ADAP
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    View All

    SEC Form 3 filed by new insider Hill Christopher James

    3 - Adaptimmune Therapeutics PLC (0001621227) (Issuer)

    10/8/25 9:00:14 PM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Chief Financial Officer Wood Gavin sold $950 worth of Ordinary Shares with a nominal value of GBP0.001 per share (96,000 units at $0.01), closing all direct ownership in the company (SEC Form 4)

    4 - Adaptimmune Therapeutics PLC (0001621227) (Issuer)

    9/3/25 5:00:21 PM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Chief Operating Officer Bertrand William C Jr sold $2,091 worth of Ordinary Shares with a nominal value of GBP0.001 per share (207,000 units at $0.01), decreasing direct ownership by 17% to 986,352 units (SEC Form 4)

    4 - Adaptimmune Therapeutics PLC (0001621227) (Issuer)

    8/29/25 6:25:42 PM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $ADAP
    Leadership Updates

    Live Leadership Updates

    View All

    Adaptimmune Reports Q1 Financial Results and Provides Business Update

    TECELRA® launch 2025 YTD metrics: 28 ATCs available; 21 patients aphresed; and 14 doses invoiced$4.0 million Tecelra net sales in Q1 2025Instituting 2025 Tecelra full year sales guidance of $35-$45 millionLete-cel on track to initiate rolling BLA submission late 2025; approval anticipated in 2026Adaptimmune had Total Liquidity1 of $60 million as of March 31, 2025; call at 8 a.m. EDT today Philadelphia, Pennsylvania and Oxford, United Kingdom--(Newsfile Corp. - May 13, 2025) - Adaptimmune Therapeutics plc (NASDAQ:ADAP), a company redefining the treatment of solid tumor cancers with cell therapy, today reported financial results and provided a business update for the first quarter ended March

    5/13/25 7:30:00 AM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Adaptimmune to Report Q1 2025 Financial and Business Updates on Tuesday, May 13, 2025

    Philadelphia, Pennsylvania and Oxford, United Kingdom--(Newsfile Corp. - May 7, 2025) - Adaptimmune Therapeutics plc (NASDAQ:ADAP), a company redefining the treatment of solid tumor cancers with cell therapy, will report financial results and provide business updates for the first quarter of 2025, before the US markets open on Tuesday, May 13, 2025. Following the announcement, the Company will host a live webcast at 8:00 a.m. EDT that same day.The press release will be available in the investor section of Adaptimmune's corporate website. A live webcast and replay can be accessed at https://www.gowebcasting.com/14032. Call in information is as follows: 1-833-821-0158 (US or Canada) or 1-647-8

    5/7/25 12:00:00 PM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Adaptimmune Provides Q4 and Full Year 2024 Business Update

    TECELRA® launch momentum accelerating – 10 patients apheresed in Q1 2025 and 3 in 2024; 20 ATCs available; all manufacturing and supply goals achievedLete-cel on track to initiate rolling BLA submission late 2025; approval anticipated 2026Corporate restructure completed in February 2025 and implementing additional cost reduction for PRAME and CD70 programsAt the end of 2024, Adaptimmune had Total Liquidity1 of $152 millionEvaluating all strategic options to maximize shareholder valuePhiladelphia, Pennsylvania and Oxford, United Kingdom--(Newsfile Corp. - March 20, 2025) - Adaptimmune Therapeutics plc (NASDAQ:ADAP), a company redefining the treatment of solid tumor cancers with cell therapy,

    3/20/25 7:00:00 AM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $ADAP
    Financials

    Live finance-specific insights

    View All

    Adaptimmune Announces Entry into Definitive Agreement for Sale of TECELRA, lete-cel, afami-cel and uza-cel Cell Therapies to US WorldMeds

    Tecelra will continue to be available to patients without interruption US WorldMeds plans to bring lete-cel to market and will continue development of uza-cel in collaboration with GalapagosPurchase price is $55m in cash to be paid upon consummation of the sale with up to $30m in potential future payments upon achievement of certain milestonesAdaptimmune will retain rights to its preclinical assets including PRAME, CD70, and its allogeneic program Adaptimmune will restructure to support the transition of these therapies to US WorldMeds and to maximize value from its remaining assetsAdaptimmune's Board of Directors determined this transaction is in the best interest of all stakeholders follow

    7/28/25 7:30:00 AM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Adaptimmune Reports Q3 2024 Financial and Business Updates

    Tecelra® launch on track with 9 Authorized Treatment Centers available to initiate patient treatment journey, and the first patient apheresed in Q3; expect first commercial revenues in Q4 and the number of treated patients to accelerate throughout 2025Lete-cel IGNYTE-ESO pivotal trial primary analysis reports 42% overall response rate in synovial sarcoma and myxoid/round cell liposarcoma (MRCLS); full data at CTOS conference on November 16Company restructuring to prioritize commercial sarcoma franchise and R&D programs with highest potential return on invested capital and transformational benefit to patientsPlanned 33% reduction in headcount in Q1, 2025 as part of approximately $300 million

    11/13/24 4:05:00 PM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Adaptimmune Reports Q2 2024 Financial and Business Updates

    Adaptimmune received U.S. FDA accelerated approval of Tecelra® (afami-cel), the first approved engineered cell therapy for a solid tumorPatients can begin treatment journey; biomarker testing available; Adaptimmune systems ready to receive ordersAt the end of Q2, Adaptimmune had Total Liquidity[1] of $214.8 millionPhiladelphia, Pennsylvania and Oxford, United Kingdom--(Newsfile Corp. - August 12, 2024) - Adaptimmune Therapeutics plc (NASDAQ:ADAP), a company redefining the treatment of solid tumor cancers with cell therapy, today reports financial results and business updates for the second quarter ended June 30, 2024. The Company will host a live webcast at 8:00 a.m. EDT (1:00 p.m. BST) tod

    8/12/24 7:00:00 AM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $ADAP
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    View All

    Amendment: SEC Form SC 13G/A filed by Adaptimmune Therapeutics plc

    SC 13G/A - Adaptimmune Therapeutics PLC (0001621227) (Subject)

    11/13/24 9:04:55 AM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form SC 13D/A filed by Adaptimmune Therapeutics plc (Amendment)

    SC 13D/A - Adaptimmune Therapeutics PLC (0001621227) (Subject)

    4/2/24 8:38:07 PM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form SC 13G/A filed by Adaptimmune Therapeutics plc (Amendment)

    SC 13G/A - Adaptimmune Therapeutics PLC (0001621227) (Subject)

    3/26/24 11:59:28 AM ET
    $ADAP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care