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    SEC Form SC 13G/A filed by ADC Therapeutics SA (Amendment)

    2/13/24 9:47:25 AM ET
    $ADCT
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $ADCT alert in real time by email
    SC 13G/A 1 d747565dsc13ga.htm SC 13G/A SC 13G/A

     

     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    Washington, D.C. 20549

     

     

    SCHEDULE 13G

    Under the Securities Exchange Act of 1934

    (Amendment No. 1)*

     

     

    ADC THERAPEUTICS SA

    (Name of Issuer)

    Common Shares

    (Title of Class of Securities)

    H0036K147

    (CUSIP Number)

    December 31, 2023

    (Date of Event which Requires Filing of this Statement)

     

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

    ☐ Rule 13d-1(b)

    ☒ Rule 13d-1(c)

    ☐ Rule 13d-1(d)

     

    *

    The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

    The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934, as amended (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

    Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications:

    Taylor H. Wilson, Esq.

    Haynes and Boone, LLP

    2801 N Harwood St, Suite 2300

    Dallas, Texas 75201

    (214) 651-5000

     

     

     


    SCHEDULE 13G

    CUSIP No. H0036K147

     

     1   

     Names of Reporting Persons

     

     Prosight Management, LP

     2  

     Check the appropriate box if a member of a Group (see instructions)

     (a) ☐  (b) ☒

     

     3  

     Sec Use Only

     

     4  

     Citizenship or Place of Organization

     

     Delaware

    Number of

    Shares  Beneficially 

    Owned by

    Each

    Reporting

    Person

    With:

       5    

     Sole Voting Power

     

     0

       6   

     Shared Voting Power

     

     6,471,800

       7   

     Sole Dispositive Power

     

     0

       8   

     Shared Dispositive Power

     

     6,471,800

     9   

     Aggregate Amount Beneficially Owned by Each Reporting Person

     

     6,471,800

    10  

     Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

     

     ☐

    11  

     Percent of class represented by amount in row (9)

     

     8.0% (1)

    12  

     Type of Reporting Person (See Instructions)

     

     IA

     

    (1)

    Based upon 80,642,527 common shares of the Issuer outstanding as of December 31, 2022, as disclosed in the Issuer’s Registration Statement on Form F-3, that was filed on March 15, 2023, by the Issuer with the U.S. Securities and Exchange Commission (the “SEC”).


    SCHEDULE 13G

    CUSIP No. H0036K147

     

     1   

     Names of Reporting Persons

     

     Prosight Fund, LP

     2  

     Check the appropriate box if a member of a Group (see instructions)

     (a) ☐  (b) ☒

     

     3  

     Sec Use Only

     

     4  

     Citizenship or Place of Organization

     

     Delaware

    Number of

    Shares  Beneficially 

    Owned by

    Each

    Reporting

    Person

    With:

       5    

     Sole Voting Power

     

     0

       6   

     Shared Voting Power

     

     568,812

       7   

     Sole Dispositive Power

     

     0

       8   

     Shared Dispositive Power

     

     568,812

     9   

     Aggregate Amount Beneficially Owned by Each Reporting Person

     

     568,812

    10  

     Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

     

     ☐

    11  

     Percent of class represented by amount in row (9)

     

     0.7% (1)

    12  

     Type of Reporting Person (See Instructions)

     

     PN

     

    (1)

    Based upon 80,642,527 common shares of the Issuer outstanding as of December 31, 2022, as disclosed in the Issuer’s Registration Statement on Form F-3, that was filed on March 15, 2023, by the Issuer with the SEC.


    SCHEDULE 13G

    CUSIP No. H0036K147

     

     1   

     Names of Reporting Persons

     

     Prosight Plus Fund, LP

     2  

     Check the appropriate box if a member of a Group (see instructions)

     (a) ☐  (b) ☒

     

     3  

     Sec Use Only

     

     4  

     Citizenship or Place of Organization

     

     Delaware

    Number of

    Shares  Beneficially 

    Owned by

    Each

    Reporting

    Person

    With:

       5    

     Sole Voting Power

     

     0

       6   

     Shared Voting Power

     

     1,688,674

       7   

     Sole Dispositive Power

     

     0

       8   

     Shared Dispositive Power

     

     1,688,674

     9   

     Aggregate Amount Beneficially Owned by Each Reporting Person

     

     1,688,674

    10  

     Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

     

     ☐

    11  

     Percent of class represented by amount in row (9)

     

     2.1% (1)

    12  

     Type of Reporting Person (See Instructions)

     

     PN

     

    (1)

    Based upon 80,642,527 common shares of the Issuer outstanding as of December 31, 2022, as disclosed in the Issuer’s Registration Statement on Form F-3, that was filed on March 15, 2023, by the Issuer with the SEC.


    SCHEDULE 13G

    CUSIP No. H0036K147

     

     1   

     Names of Reporting Persons

     

     Prosight Partners, LLC

     2  

     Check the appropriate box if a member of a Group (see instructions)

     (a) ☐  (b) ☒

     

     3  

     Sec Use Only

     

     4  

     Citizenship or Place of Organization

     

     Delaware

    Number of

    Shares  Beneficially 

    Owned by

    Each

    Reporting

    Person

    With:

       5    

     Sole Voting Power

     

     0

       6   

     Shared Voting Power

     

     6,471,800

       7   

     Sole Dispositive Power

     

     0

       8   

     Shared Dispositive Power

     

     6,471,800

     9   

     Aggregate Amount Beneficially Owned by Each Reporting Person

     

     6,471,800

    10  

     Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

     

     ☐

    11  

     Percent of class represented by amount in row (9)

     

     8.0% (1)

    12  

     Type of Reporting Person (See Instructions)

     

     OO

     

    (1)

    Based upon 80,642,527 common shares of the Issuer outstanding as of December 31, 2022, as disclosed in the Issuer’s Registration Statement on Form F-3, that was filed on March 15, 2023, by the Issuer with the SEC.


    SCHEDULE 13G

    CUSIP No. H0036K147

     

     1   

     Names of Reporting Persons

     

     W. Lawrence Hawkins

     2  

     Check the appropriate box if a member of a Group (see instructions)

     (a) ☐  (b) ☒

     

     3  

     Sec Use Only

     

     4  

     Citizenship or Place of Organization

     

     United States of America

    Number of

    Shares  Beneficially 

    Owned by

    Each

    Reporting

    Person

    With:

       5    

     Sole Voting Power

     

     0

       6   

     Shared Voting Power

     

     6,471,800

       7   

     Sole Dispositive Power

     

     0

       8   

     Shared Dispositive Power

     

     6,471,800

     9   

     Aggregate Amount Beneficially Owned by Each Reporting Person

     

     6,471,800

    10  

     Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

     

     ☐

    11  

     Percent of class represented by amount in row (9)

     

     8.0% (1)

    12  

     Type of Reporting Person (See Instructions)

     

     IN, HC

     

    (1)

    Based upon 80,642,527 common shares of the Issuer outstanding as of December 31, 2022, as disclosed in the Issuer’s Registration Statement on Form F-3, that was filed on March 15, 2023, by the Issuer with the SEC.


    Item 1.

     

      (a)

    Name of Issuer:

    ADC Therapeutics SA (the “Issuer”)

     

      (b)

    Address of Issuer’s Principal Executive Offices:

    Biopôle

    Route de la Corniche 3B

    1066 Epalinges

    Switzerland

    Item 2.

     

    (a)

    Name of Person Filing:

    This statement is jointly filed by and on behalf of each of Prosight Management, LP, a Delaware limited partnership (“Prosight Management”), Prosight Fund, LP, a Delaware limited partnership (“Prosight Fund”), Prosight Plus Fund, LP, a Delaware limited partnership (“Prosight Plus Fund”), Prosight Partners, LLC, a Delaware limited liability company (“Prosight Partners”), and W. Lawrence Hawkins (collectively referred herein as “Reporting Persons”). Prosight Management is the general partner and investment manager of, and may be deemed to indirectly beneficially own securities owned by, Prosight Fund and Prosight Plus Fund. Prosight Management is a sub-advisor for certain separate managed accounts (collectively, the “Managed Accounts”) and may be deemed to indirectly beneficially own securities owned by the Managed Accounts. Prosight Partners is the general partner of, and may be deemed to beneficially own, securities beneficially owned by Prosight Management. Mr. Hawkins is the sole manager of, and may be deemed to beneficially own securities beneficially owned by, Prosight Partners. Prosight Fund, Prosight Plus Fund and the Managed Accounts are the record and direct beneficial owner of the Common Shares covered by this statement. Prosight Fund disclaims beneficial ownership of the Common Shares held by the Managed Accounts and the Common Shares held by Prosight Plus Fund. Prosight Plus Fund disclaims beneficial ownership of the Common Shares held by the Managed Accounts and the Common Shares held by Prosight Fund.

    Each Reporting Person declares that neither the filing of this statement nor anything herein shall be construed as an admission that such person is, for the purposes of Section 13(d) or 13(g) of the Act or any other purpose, the beneficial owner of any securities covered by this statement.

    Each Reporting Person may be deemed to be a member of a group with respect to the Issuer or securities of the Issuer for the purpose of Section 13(d) or 13(g) of the Act. Each of the Reporting Persons declares that neither the filing of this statement nor anything herein shall be construed as an admission that such person is, for the purpose of Section 13(d) or 13(g) of the Act or any other purpose, (i) acting (or has agreed or is agreeing to act together with any other person) as a partnership, limited partnership, syndicate, or other group for the purpose of acquiring, holding, or disposing of securities of the Issuer or otherwise with respect to the Issuer or any securities of the Issuer or (ii) a member of any group with respect to the Issuer or any securities of the Issuer.

     

    (b)

    Address of Principal Business Office or, if None, Residence:

    The address of the principal business office of each of the Reporting Persons is c/o Prosight Management, LP, 5956 Sherry Lane, Suite 1365, Dallas, Texas 75225.


    (c)

    Citizenship:

    See Item 4 on the cover page(s) hereto.

     

    (d)

    Title and Class of Securities:

    Common Shares, par value CHF 0.08 per share (“Common Shares”)

     

    (e)

    CUSIP No.:

    H0036K147 

     

    Item 3.

    If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

     

    (a)   ☐   Broker or dealer registered under Section 15 of the Act;
    (b)   ☐   Bank as defined in Section 3(a)(6) of the Act;
    (c)   ☐   Insurance company as defined in Section 3(a)(19) of the Act;
    (d)   ☐   Investment company registered under Section 8 of the Investment Company Act of 1940;
    (e)   ☐   An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E);
    (f)   ☐   An employee benefit plan or endowment fund in accordance with Rule 13d-1(b)(1)(ii)(F);
    (g)   ☐   A parent holding company or control person in accordance with Rule 13d-1(b)(1)(ii)(G);
    (h)   ☐   A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
    (i)   ☐   A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940;
    (j)   ☐   A non-U.S. institution in accordance with Rule 240.13d-1(b)(1)(ii)(J);
    (k)   ☐   Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K). If filing as a non-U.S. institution in accordance with Rule 240.13d-1(b)(1)(ii)(J), please specify the type of institution:

     

    Item 4.

    Ownership

     

    (a)

    Amount Beneficially Owned as of the time of filing: See Item 9 on the cover pages(s) hereto.

     

    (b)

    Percent of Class as of the time of filing: See Item 11 on the cover page(s) hereto.

     

    (c)

    As of the time of filing, number of shares as to which such person has:

     

      (i)

    Sole power to vote or to direct the vote: See Item 5 on the cover pages hereto.

     

      (ii)

    Shared power to vote or to direct the vote: See Item 6 on the cover pages hereto.

     

      (iii)

    Sole power to dispose or to direct the disposition of: See Item 7 on the cover pages hereto.

     

      (iv)

    Shared power to dispose or to direct the disposition of: See Item 8 on the cover pages hereto.


    Item 5.

    Ownership of Five Percent or Less of a Class.

    If this statement is being filed to report the fact that as of the date hereof the Reporting Persons have ceased to be the beneficial owners of more than five percent of the class of securities, check the following [ ].

     

    Item 6.

    Ownership of more than Five Percent on Behalf of Another Person.

    Not applicable

     

    Item 7.

    Identification and classification of the subsidiary which acquired the security being reported on by the parent holding company or control person.

    Not applicable

     

    Item 8.

    Identification and classification of members of the group.

    Not applicable

     

    Item 9.

    Notice of Dissolution of Group.

    Not applicable

     

    Item 10.

    Certifications.

    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the Issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect other than activities solely in connection with a nomination under § 240.14a-11.


    SIGNATURE

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

    Dated: February 13, 2024

     

    PROSIGHT MANAGEMENT, LP
    By:   Prosight Partners, LLC
    Its:   General Partner
    By:  

    /s/ W. Lawrence Hawkins

    Name:   W. Lawrence Hawkins
    Title:   Sole Manager
    PROSIGHT FUND, LP
    By:   Prosight Management, LP
    Its:   General Partner
    By:   Prosight Partners, LLC
    Its:   General Partner
    By:  

    /s/ W. Lawrence Hawkins

    Name:   W. Lawrence Hawkins
    Title:   Sole Manager
    PROSIGHT PLUS FUND, LP
    By:   Prosight Management, LP
    Its:   General Partner
    By:   Prosight Partners, LLC
    Its:   General Partner
    By:  

    /s/ W. Lawrence Hawkins

    Name:   W. Lawrence Hawkins
    Title:   Sole Manager
    PROSIGHT PARTNERS, LLC
    By:  

    /s/ W. Lawrence Hawkins

    Name:   W. Lawrence Hawkins
    Title:   Sole Manager
    W. LAWRENCE HAWKINS

    /s/ W. Lawrence Hawkins


    EXHIBIT INDEX

     

    Exhibit

      

    Description of Exhibit

    99.1    Joint Filing Agreement (incorporated herein by reference to Exhibit 99.1 to the Schedule 13G filed on April 17, 2023, by the Reporting Persons with the SEC).
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      £90m ($114m) series A co-led by new leading life science investors Novo Holdings and AbingworthAdditional new investors British Patient Capital, Cancer Research Horizons and Lilly participated alongside founding investors Brandon Capital and Sofinnova PartnersFunds will be used to build out Myricx Bio's proprietary N-Myristoyltransferase inhibitor (NMTi) antibody-drug conjugate (ADC) payload platform and advance its pipeline of NMTi-ADCs through clinical proof of concept targeting clinically validated tumour-associated antigensCompany to establish laboratory operations in London's biotech hub, and expand its management and R&D teamsMichael Bauer from Novo Holdings and Lucille Conroy from Abi

      7/8/24 2:00:00 AM ET
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    • ADC Therapeutics Set to Join Russell 2000® and Russell 3000® Indexes

      LAUSANNE, Switzerland, June 27, 2024 (GLOBE NEWSWIRE) -- ADC Therapeutics SA (NYSE:ADCT) today announced that the Company is set to join the Russell 2000® Index and the broad-market Russell 3000® Index at the conclusion of the 2024 Russell US Indexes annual reconstitution, effective at the open of US equity markets on Monday, July 1, 2024. "We are pleased to be joining the Russell 2000® Index," said Ameet Mallik, Chief Executive Officer of ADC Therapeutics. "This is a significant benchmark validating the focused execution of our corporate and capital allocation strategy and our progress toward multiple upcoming expected milestones throughout our hematology and solid tumor portfolios." Th

      6/27/24 7:15:00 AM ET
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    • Myricx Bio Appoints Dr Chris Martin, Biotech Entrepreneur and ADC Pioneer, as Chairman of its Board of Directors

      LONDON, Nov. 15, 2023 (GLOBE NEWSWIRE) -- Myricx Bio (‘Myricx'), a UK biotech company focused on the discovery and development of a completely novel class of antibody-drug conjugate (ADC) payloads based on N-Myristoyltransferase inhibition (NMTi), today announces the appointment of Dr Chris Martin as independent Chairman to its Board of Directors. Dr Martin is a renowned biotech company founder, director and entrepreneur, and a pioneer and leader in the ADC space. Dr Martin was instrumental in co-founding ADC Therapeutics (NYSE:ADCT) in Jan 2012 and served as its CEO since inception until May 2022. Under his leadership, ADC Therapeutics grew from a private biotech start-up to a New York

      11/15/23 3:00:00 AM ET
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    • ADC Therapeutics Reports First Quarter 2025 Financial Results and Provides Operational Update

      LOTIS-7 abstract accepted for presentation at the European Hematology Association 2025 Congress (EHA2025) and the 18th International Conference on Malignant Lymphoma (ICML); ZYNLONTA® plus glofitamab demonstrated ORR of 95.5% and CR of 90.9% with encouraging safety and tolerability Forty patient enrollment reached in LOTIS-7 trial dose expansion arm in patients with relapsed/refractory DLBCL Cash runway expected to fund multiple catalysts into the second half of 2026 Company to host conference call today at 8:30 a.m. EDT LAUSANNE, Switzerland, May 14, 2025 /PRNewswire/ -- ADC Therapeutics SA (NYSE:ADCT), a commercial-stage global leader and pioneer in the field of antibody drug conjugates (

      5/14/25 8:00:00 AM ET
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    • ADC Therapeutics to Host First Quarter 2025 Financial Results Conference Call on May 14, 2025

      LAUSANNE, Switzerland, May 8, 2025 /PRNewswire/ -- ADC Therapeutics SA (NYSE:ADCT), a commercial-stage global leader and pioneer in the field of antibody drug conjugates (ADCs), today announced that it will host a conference call and live webcast on Wednesday, May 14, 2025, at 8:30 a.m. EDT to report financial results for the first quarter 2025 and provide operational updates. To access the conference call, please register here. The participant toll-free dial-in number is 1-800-836-8184 for North America and Canada. It is recommended that you join 10 minutes before the event,

      5/8/25 7:15:00 AM ET
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    • ADC Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Operational Update

      Initial data from LOTIS-7 Phase 1b trial of ZYNLONTA® plus glofitamab demonstrated clinically meaningful benefit with 94% best ORR and 72% CR rate; data update expected in second quarter 2025 Completed enrollment in LOTIS-5 Phase 3 confirmatory trial of ZYNLONTA plus rituximab in patients with 2L+ DLBCL; data update anticipated in late 2025 once PFS events reached $250.9M in cash as of December 31, 2024, provides runway expected to fund operations into the second half of 2026 Company to host conference call today at 8:30 a.m. EDT LAUSANNE, Switzerland, March 27, 2025 /PRNewswire/ -- ADC Therapeutics SA (NYSE:ADCT), a commercial-stage global leader and pioneer in the field of antibody drug c

      3/27/25 7:30:00 AM ET
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    • Amendment: SEC Form SC 13G/A filed by ADC Therapeutics SA

      SC 13G/A - ADC Therapeutics SA (0001771910) (Subject)

      11/14/24 9:00:57 PM ET
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    • Amendment: SEC Form SC 13G/A filed by ADC Therapeutics SA

      SC 13G/A - ADC Therapeutics SA (0001771910) (Subject)

      11/13/24 8:58:56 AM ET
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    • Amendment: SEC Form SC 13G/A filed by ADC Therapeutics SA

      SC 13G/A - ADC Therapeutics SA (0001771910) (Subject)

      11/13/24 8:30:55 AM ET
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