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    SEC Form SC 13G/A filed by Aligos Therapeutics Inc. (Amendment)

    2/14/24 4:21:51 PM ET
    $ALGS
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $ALGS alert in real time by email
    SC 13G/A 1 tm242424d9_sc13ga.htm SC 13G/A

     

     

    SCHEDULE 13G

     

    SECURITIES AND EXCHANGE COMMISSION
    WASHINGTON, DC 20549

     

    Under the Securities Exchange Act of 1934
    (Amendment No. 1)*

     

    Aligos Therapeutics, Inc.

    (Name of Issuer)

     

    Common Stock, par value $0.0001 per share

    (Title of Class of Securities)

     

    01626L105
    (CUSIP Number)
     
    December 31, 2023
    (Date of Event which Requires Filing of this Statement)

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

     

    x Rule 13d-1(b)

     

    ¨ Rule 13d-1(c)

     

    ¨ Rule 13d-1(d)

     

    *The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

     

    The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (the “Act”) or otherwise subject to the liabilities of that section of the Act, but shall be subject to all other provisions of the Act (however, see the Notes).

     

     

     

     

     

    CUSIP No. 01626L105

     

    1

    NAMES OF REPORTING PERSONS

     

    Baker Bros. Advisors LP

    2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)

    (a) ¨
    (b) 
    ¨

     

    3

    SEC USE ONLY

     

    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON
    WITH

     

    5

    SOLE VOTING POWER

     

    3,664,013 (1)

    6

    SHARED VOTING POWER

     

    -0-

    7

    SOLE DISPOSITIVE POWER

     

    3,664,013 (1)

    8

    SHARED DISPOSITIVE POWER

     

    -0-

    9

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    3,664,013 (1)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
    (See Instructions)

    ¨

     

     

    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    4.99% (1)(2)

    12

    TYPE OF REPORTING PERSON (See Instructions)

     

    IA, PN

    (1)Includes 1,587,613 shares of common stock (“Common Stock”) of Aligos Therapeutics, Inc. (the “Issuer”) issuable upon the conversion of Non-Voting Common Stock (as defined in Item 4 and subject to limitations as described therein) held directly by the Funds (as defined in Item 4).
    (2)Based upon 71,839,510 shares of Common Stock outstanding as of October 31, 2023, as reported in the Issuer’s Prospectus filed with the Securities and Exchange Commission (“SEC”) on November 28, 2023, plus 1,587,613 shares of Common Stock issuable upon conversion of Non-Voting Common Stock (as defined in Item 4) that are subject to the limitations on conversion described in Item 4.

     

     

     

     

    CUSIP No. 01626L105

     

    1

    NAMES OF REPORTING PERSONS

     

    Baker Bros. Advisors (GP) LLC

    2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)

    (a) ¨
    (b) 
    ¨

     

    3

    SEC USE ONLY

     

    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON
    WITH

     

    5

    SOLE VOTING POWER

     

    3,664,013 (1)

    6

    SHARED VOTING POWER

     

    -0-

    7

    SOLE DISPOSITIVE POWER

     

    3,664,013 (1)

    8

    SHARED DISPOSITIVE POWER

     

    -0-

    9

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    3,664,013 (1)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
    (See Instructions)

    ¨

     

     

    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    4.99% (1)(2)

    12

    TYPE OF REPORTING PERSON (See Instructions)

     

    HC, OO

    (1)Includes 1,587,613 shares of Common Stock issuable upon the conversion of Non-Voting Common Stock (as defined in Item 4 and subject to limitations as described therein) held directly by the Funds (as defined in Item 4).
    (2)Based upon 71,839,510 shares of Common Stock outstanding as of October 31, 2023, as reported in the Issuer’s Prospectus filed with the SEC on November 28, 2023, plus 1,587,613 shares of Common Stock issuable upon conversion of Non-Voting Common Stock (as defined in Item 4) that are subject to the limitations on conversion described in Item 4.

     

     

     

     

    CUSIP No. 01626L105

     

    1

    NAMES OF REPORTING PERSONS

     

    Felix J. Baker

    2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)

    (a) ¨
    (b) 
    ¨

     

    3

    SEC USE ONLY

     

    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    United States

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON
    WITH

     

    5

    SOLE VOTING POWER

     

    3,664,013 (1)

    6

    SHARED VOTING POWER

     

    -0-

    7

    SOLE DISPOSITIVE POWER

     

    3,664,013 (1)

    8

    SHARED DISPOSITIVE POWER

     

    -0-

    9

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    3,664,013 (1)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
    (See Instructions)

    ¨

     

     

    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    4.99% (1)(2)

    12

    TYPE OF REPORTING PERSON (See Instructions)

     

    IN, HC

    (1)Includes 1,587,613 shares of Common Stock issuable upon the conversion of Non-Voting Common Stock (as defined in Item 4 and subject to limitations as described therein) held directly by the Funds (as defined in Item 4).
    (2)Based upon 71,839,510 shares of Common Stock outstanding as of October 31, 2023, as reported in the Issuer’s Prospectus filed with the SEC on November 28, 2023, plus 1,587,613 shares of Common Stock issuable upon conversion of Non-Voting Common Stock (as defined in Item 4) that are subject to the limitations on conversion described in Item 4.

     

     

     

     

    CUSIP No. 01626L105

     

    1

    NAMES OF REPORTING PERSONS

     

    Julian C. Baker

    2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)

    (a) ¨
    (b) 
    ¨

     

    3

    SEC USE ONLY

     

    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    United States

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON
    WITH

     

    5

    SOLE VOTING POWER

     

    3,664,013 (1)

    6

    SHARED VOTING POWER

     

    -0-

    7

    SOLE DISPOSITIVE POWER

     

    3,664,013 (1)

    8

    SHARED DISPOSITIVE POWER

     

    -0-

    9

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    3,664,013 (1)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
    (See Instructions)

    ¨

     

     

    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    4.99% (1)(2)

    12

    TYPE OF REPORTING PERSON (See Instructions)

     

    IN, HC

    (1)Includes 1,587,613 shares of Common Stock issuable upon the conversion of Non-Voting Common Stock (as defined in Item 4 and subject to limitations as described therein) held directly by the Funds (as defined in Item 4).
    (2)Based upon 71,839,510 shares of Common Stock outstanding as of October 31, 2023, as reported in the Issuer’s Prospectus filed with the SEC on November 28, 2023, plus 1,587,613 shares of Common Stock issuable upon conversion of Non-Voting Common Stock (as defined in Item 4) that are subject to the limitations on conversion described in Item 4.

     

     

     

     

    Amendment No. 1 to Schedule 13G

     

    This Amendment No. 1 to Schedule 13G amends and restates the previously filed Schedule 13G filed by Baker Bros. Advisors LP (the “Adviser”), Baker Bros. Advisors (GP) LLC (the “Adviser GP”), Julian C. Baker and Felix J. Baker (collectively, the “Reporting Persons”). Except as supplemented herein, such statements, as heretofore amended and supplemented, remain in full force and effect.

     

    Item 1(a)Name of Issuer:

     

    Aligos Therapeutics, Inc. (the “Issuer”)

     

    Item 1(b)Address of Issuer’s Principal Executive Offices:

     

    One Corporate Drive, 2nd Floor

     

    South San Francisco, CA 94080

     

    Item 2(a)Name of Person Filing:

     

    This Amendment No. 1 is being filed jointly by the Reporting Persons.

     

    Item 2(b)Address of Principal Business Office or, if None, Residence:

     

    The business address of each of the Reporting Persons is:

     

    c/o Baker Bros. Advisors LP

     

    860 Washington Street, 3rd Floor

     

    New York, NY 10014

     

    (212) 339-5690

     

    Item 2(c)Citizenship:

     

    The Adviser is a limited partnership organized under the laws of the State of Delaware. The Adviser GP is a limited liability company organized under the laws of the State of Delaware. The citizenship of each of Julian C. Baker and Felix J. Baker is the United States of America.

     

    Item 2(d)Title of Class of Securities:

     

    Common Stock, par value $0.0001 per share (“Common Stock”).

     

    Item 2(e)CUSIP Number:

     

    01626L105

     

     

     

     

    Item 3If this statement is filed pursuant to §§240.13d-1(b) or (c), check whether the person filing is a:

     

    (a) ¨ Broker or dealer registered under Section 15 of the Exchange Act.

     

    (b) ¨ Bank as defined in section 3(a)(6) of the Exchange Act.

     

    (c) ¨ Insurance company as defined in section 3(a)(19) of the Exchange Act.

     

    (d) ¨ Investment company registered under section 8 of the Investment Company Act of 1940.

     

    (e) x An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E).

     

    (f) ¨ An employee benefit plan or endowment fund in accordance with Rule 13d-1(b)(1)(ii)(F).

     

    (g) x A parent holding company or control person in accordance with Rule  13d-1(b)(1)(ii)(G).

     

    (h) ¨ A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act.

     

    (i) ¨ A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940.

     

    (j) ¨ Group, in accordance with Rule 13d-1(b)(1)(ii)(J).

     

    Item 4Ownership:

     

    Items 5 through 9 and 11 of each of the cover pages to this Amendment No. 1 are incorporated herein reference. Set forth below is the aggregate number of shares of Common Stock directly held by each of Baker Brothers Life Sciences, L.P. (“Life Sciences”) and 667, L.P. (“667”, and together with Life Sciences, the “Funds”) which may be deemed to be indirectly beneficially owned by the Reporting Persons, as well as Common Stock that may be acquired upon conversion of non-voting common stock into Common Stock on a 1-for-1 basis without consideration (“Non-Voting Common Stock”), subject to the limitations on conversion described below and shares of Common Stock that may be acquired upon exercise of pre-funded warrants to purchase Common Stock at an exercise price of $0.0001 per share with no expiration date (the “Prefunded Warrants”), subject to the limitations on exercise described below and shares of Common Stock that may be acquired upon exercise of warrants to purchase Common Stock at an exercise price of $0.7568 per share with an expiration date of October 25, 2030 (the “2030 Warrants”), subject to the limitations on exercise described below.

     

    The information set forth below is based on 71,839,510 shares of Common Stock outstanding as of October 31, 2023, as reported in the Issuer’s Prospectus filed with the Securities and Exchange Commission on November 28, 2023. Such percentage figures are calculated in accordance with Rule 13d-3 under the Securities Exchange Act of 1934, as amended (the “Exchange Act”).

     

      Holder  Number of Shares of Common
    Stock we own or have the right
    to acquire within 60 days
       Percent of Class 
    Outstanding
     
      667, L.P.   264,369    0.36%
      Baker Brothers Life Sciences, L.P.   3,399,644    4.63%
      Total   3,664,013    4.99%

     

     

     

     

    Non-Voting Common Stock is only convertible to the extent that after giving effect to such exercise the holders thereof, their affiliates and any person who are members of a Section 13(d) group with the holders or its affiliates would beneficially own in the aggregate, for purposes of Rule 13d-3 under the Exchange Act, no more than 4.99% of the outstanding Common Stock (“Beneficial Ownership Limitation”). By written notice to the Issuer, the Funds may from time to time increase or decrease the Beneficial Ownership Limitation applicable to that Fund. Any such increase will not be effective until the 61st day after such notice is delivered to the Issuer. As a result of this restriction, the number of shares of Common Stock that may be issued upon conversion of Non-Voting Common Stock by the above holders may change depending upon changes in the outstanding Common Stock.

     

    The Prefunded Warrants are only exercisable to the extent that after giving effect or immediately prior to such exercise the holders thereof, their affiliates and any person who are members of a Section 13(d) group with the holders or one of their affiliates would beneficially own in the aggregate, for purposes of Rule 13d-3 under the Exchange Act, no more than 4.99% of the outstanding Common Stock (“PFW Beneficial Ownership Limitation”). By written notice to the Issuer, the Funds may from time to time increase or decrease the PFW Beneficial Ownership Limitation applicable to that Fund to any other percentage not in excess of 19.99%. Any such increase will not be effective until the 61st day after such notice is delivered to the Issuer. As a result of this restriction, the number of shares of Common Stock that may be issued upon exercise of the Prefunded Warrants by the above holders may change depending upon changes in the outstanding Common Stock.

     

    The 2030 Warrants are only exercisable to the extent that after giving effect or immediately prior to such exercise the holders thereof, their affiliates and any person who are members of a Section 13(d) group with the holders or one of their affiliates would beneficially own in the aggregate, for purposes of Rule 13d-3 under the Exchange Act, no more than 4.99% of the outstanding Common Stock (“Maximum Percentage”). By written notice to the Issuer, the Funds may from time to time increase or decrease the Maximum Percentage applicable to that Fund to any other percentage not in excess of 19.99%. Any such increase will not be effective until the 61st day after such notice is delivered to the Issuer. As a result of this restriction, the number of shares of Common Stock that may be issued upon exercise of the 2030 Warrants by the above holders may change depending upon changes in the outstanding Common Stock.

     

    The Adviser GP, Felix J. Baker and Julian C. Baker as managing members of the Adviser GP, and the Adviser may be deemed to be beneficial owners of securities of the Issuer directly held by the Funds.

     

    The Adviser GP is the sole general partner of the Adviser. Pursuant to the management agreements, as amended, among the Adviser, Life Sciences and 667 and their respective general partners, the Funds’ respective general partners relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds, and thus the Adviser has completed and unlimited discretion and authority with respect to the Funds’ investments and voting power over investments.

     

    Item 5Ownership of Five Percent or Less of a Class:

     

    If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following x.

     

     

     

     

    Item 6Ownership of More than Five Percent on Behalf of Another Person:

     

    N/A

     

    Item 7Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person:

     

    The information in Item 4 is incorporated herein by reference.

     

    Item 8Identification and Classification of Members of the Group.

     

    N/A

     

    Item 9Notice of Dissolution of Group:

     

    N/A

     

    Item 10Certification:

     

    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.

     

     

     

     

    SIGNATURE

     

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     

    February 14, 2024

     

      BAKER BROS. ADVISORS LP

    By: Baker Bros. Advisors (GP) LLC, its general partner
     
      By: /s/ Scott L. Lessing
        Name: Scott L. Lessing
    Title: President

     

      BAKER BROS. ADVISORS (GP) LLC
         
      By: /s/ Scott L. Lessing
        Name: Scott L. Lessing
    Title: President      

     

      /s/ Julian C. Baker
        Julian C. Baker
       
      /s/ Felix J. Baker
        Felix J. Baker

     

     

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      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $ALGS
    Large Ownership Changes

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    • Amendment: SEC Form SC 13G/A filed by Aligos Therapeutics Inc.

      SC 13G/A - Aligos Therapeutics, Inc. (0001799448) (Subject)

      11/14/24 6:57:50 PM ET
      $ALGS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Amendment: SEC Form SC 13G/A filed by Aligos Therapeutics Inc.

      SC 13G/A - Aligos Therapeutics, Inc. (0001799448) (Subject)

      11/14/24 6:19:11 PM ET
      $ALGS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Amendment: SEC Form SC 13G/A filed by Aligos Therapeutics Inc.

      SC 13G/A - Aligos Therapeutics, Inc. (0001799448) (Subject)

      11/14/24 5:03:16 PM ET
      $ALGS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $ALGS
    Leadership Updates

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    • Aligos Therapeutics Appoints David Perry as Vice President of Business Development

      SOUTH SAN FRANCISCO, Calif., Oct. 01, 2024 (GLOBE NEWSWIRE) -- Aligos Therapeutics, Inc. (NASDAQ:ALGS) a clinical stage biopharmaceutical company focused on improving patient outcomes through best-in-class therapies for liver and viral diseases, today announced the appointment of David Perry as Vice President of Business Development, effective immediately. "We are pleased to welcome David to the Aligos team during this exciting time for the company," said Lesley Ann Calhoun, Executive Vice President and Chief Financial Officer at Aligos. "David's expertise in leading valuable partnerships will be instrumental as we strategically look to maximize the potential of our best-in-class pipeline

      10/1/24 8:00:00 AM ET
      $ALGS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Aligos Therapeutics Strengthens Senior Leadership Team with the Appointment of Hardean Achneck, MD as Chief Medical Officer

      SOUTH SAN FRANCISCO, Calif., Sept. 24, 2024 (GLOBE NEWSWIRE) -- Aligos Therapeutics, Inc. (NASDAQ:ALGS), a clinical stage biopharmaceutical company focused on improving patient outcomes through best-in-class therapies for liver and viral diseases, today announced the appointment of Dr. Hardean Achneck as Chief Medical Officer, effective immediately. Dr. Achneck will lead the Company's global clinical development efforts and serve as a member of Aligos' Senior Leadership Team. Dr. Hardean Achneck is a seasoned clinical development executive with extensive experience across multiple therapeutic areas, including hepatology and infectious diseases. "I am excited to welcome Hardean to Aligos a

      9/24/24 8:00:00 AM ET
      $ALGS
      $HAE
      $NVO
      $PLRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
      Medical/Dental Instruments
      Biotechnology: Pharmaceutical Preparations
    • Aligos Therapeutics Strengthens Board with Two New Independent Directors

      SOUTH SAN FRANCISCO, Calif., Aug. 08, 2024 (GLOBE NEWSWIRE) --  Aligos Therapeutics, Inc. (NASDAQ:ALGS, "Aligos", the "Company"))), a clinical stage biopharmaceutical company focused on developing novel therapeutics to address unmet medical needs in liver and viral diseases, today announced the appointment of Heather Preston, M.D. and Margarita Chavez, J.D. as Class II Independent Directors to the Board of Directors, effective August 7, 2024. Dr. Preston will join the Nominating and Corporate Governance Committee as Chair and Ms. Chavez will join the Audit Committee. "We are pleased to announce the appointment of Dr. Heather Preston and Margarita Chavez to our Board of Directors," stated

      8/8/24 4:05:00 PM ET
      $ALGS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $ALGS
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

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    • H.C. Wainwright initiated coverage on Aligos Therapeutics with a new price target

      H.C. Wainwright initiated coverage of Aligos Therapeutics with a rating of Buy and set a new price target of $75.00

      8/19/24 6:51:07 AM ET
      $ALGS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Aligos Therapeutics upgraded by Piper Sandler with a new price target

      Piper Sandler upgraded Aligos Therapeutics from Neutral to Overweight and set a new price target of $3.00 from $2.00 previously

      1/6/23 9:05:04 AM ET
      $ALGS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Aligos Therapeutics upgraded by Jefferies with a new price target

      Jefferies upgraded Aligos Therapeutics from Hold to Buy and set a new price target of $3.00 from $2.50 previously

      1/6/23 9:03:03 AM ET
      $ALGS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care