• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • AI Executive AssistantNEW
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • AI Executive AssistantNEW
  • Settings
  • RSS Feeds
PublishGo to AppAI Helper
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlertsPublish with Us
    Company
    AboutQuantisnow PlusContactJobsAI employees for your businessNEW
    Legal
    Terms of usePrivacy policyCookie policy

    SEC Form SC 13G/A filed by BioCryst Pharmaceuticals Inc. (Amendment)

    2/13/24 5:00:45 PM ET
    $BCRX
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $BCRX alert in real time by email
    SC 13G/A 1 tv0435-biocrystpharmaceutica.htm SCHEDULE 13G/A biocrystpharmaceuticalsinc

    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549

    Schedule 13G

    Under the Securities Exchange Act of 1934
    (Amendment No.: 6)*

    Name of issuer:  BioCryst Pharmaceuticals Inc

    Title of Class of Securities:  Common Stock

    CUSIP Number:  09058V103

    Date of Event Which Requires Filing of this Statement: December 29, 2023

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

    ☒ Rule 13d-1(b)

    ☐ Rule 13d-1(c)

    ☐ Rule 13d-1(d)

    *The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

    The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

    (Continued on the following page(s))

     

     

    13G

    CUSIP No.:  09058V103

    1.  NAME OF REPORTING PERSON
    I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

    The Vanguard Group - 23-1945930

    2.  CHECK THE APPROPRIATE [LINE] IF A MEMBER OF A GROUP

    A. 

    B.  X

    3.  SEC USE ONLY

    4.  CITIZENSHIP OF PLACE OF ORGANIZATION

    Pennsylvania

    (For questions 5-8, report the number of shares beneficially owned by each reporting person with:)

    5.  SOLE VOTING POWER

    0

    6.  SHARED VOTING POWER

    291,613

    7.  SOLE DISPOSITIVE POWER

    17,263,150

    8.  SHARED DISPOSITIVE POWER

    500,570

    9.  AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

    17,763,720

    10.  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

    N/A

    11.  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

    8.67%

    12.  TYPE OF REPORTING PERSON

    IA

     

     

    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549

    Schedule 13G
    Under the Securities Act of 1934

    Item 1(a) - Name of Issuer:

    BioCryst Pharmaceuticals Inc

    Item 1(b) - Address of Issuer's Principal Executive Offices:

    4505 Emperor Boulevard, Suite 200
    Durham, NC 27703-8457

    Item 2(a) - Name of Person Filing:

    The Vanguard Group - 23-1945930

    Item 2(b) – Address of Principal Business Office or, if none, residence:

    100 Vanguard Blvd.
    Malvern, PA 19355

    Item 2(c) – Citizenship:

    Pennsylvania

    Item 2(d) - Title of Class of Securities:

    Common Stock

    Item 2(e) - CUSIP Number

    09058V103

    Item 3 - Type of Filing:

    This statement is being filed pursuant to Rule 13d-1.  An investment adviser in accordance with §240.13d-1(b)(1)(ii)(E).

    Item 4 - Ownership:

      (a) Amount Beneficially Owned:

      (b) Percent of Class:

     

     

    (c)  Number of shares as to which such person has:

    (i)  sole power to vote or direct to vote:  

    (ii)  shared power to vote or direct to vote:  

    (iii)  sole power to dispose of or to direct the disposition of:  

    (iv)  shared power to dispose or to direct the disposition of:  

    Comments:

    The responses to questions 5 through 9 and 11 on the cover page(s) are incorporated by reference into this Item 4.  

    Item 5 - Ownership of Five Percent or Less of a Class:

    If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than 5 percent of the class of securities, check the following ☐

    Item 6 - Ownership of More Than Five Percent on Behalf of Another Person:

    The Vanguard Group, Inc.'s clients, including investment companies registered under the Investment Company Act of 1940 and other managed accounts, have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, the securities reported herein.

    No one other person's interest in the securities reported herein is more than 5%.

    Item 7 - Identification and Classification of the Subsidiary Which Acquired The Security Being Reported on by the Parent Holding Company:

    Not applicable

    Item 8 - Identification and Classification of Members of Group:

    Not applicable

    Item 9 - Notice of Dissolution of Group:

    Not applicable

    Item 10 - Certification:

    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under §240.14a-11.

    Signature

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

    Date:  February 13, 2024

    By /s/ Ashley Grim
    Name: Ashley Grim
    Title:  Head of Global Fund Administration

    Get the next $BCRX alert in real time by email

    Crush Q3 2025 with the Best AI Executive Assistant

    Stay ahead of the competition with Tailforce.ai - your AI-powered business intelligence partner.

    AI-Powered Inbox
    Context-aware email replies
    Strategic Decision Support
    Get Started with Tailforce.ai

    Recent Analyst Ratings for
    $BCRX

    DatePrice TargetRatingAnalyst
    4/29/2025$20.00Overweight
    Cantor Fitzgerald
    2/25/2025$15.00Outperform
    Wedbush
    11/20/2023$10.00Overweight
    JP Morgan
    9/18/2023$9.00 → $10.00Sector Perform → Outperform
    RBC Capital Mkts
    8/4/2023$11.00Hold → Buy
    Jefferies
    7/13/2023$10.00Neutral → Buy
    BofA Securities
    2/22/2023$14.00Hold → Buy
    Needham
    11/2/2022$14.00 → $16.00In-line → Outperform
    Evercore ISI
    More analyst ratings

    $BCRX
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • Director Sanders Machelle was granted 12,500 shares, increasing direct ownership by 45% to 40,242 units (SEC Form 4)

      4 - BIOCRYST PHARMACEUTICALS INC (0000882796) (Issuer)

      6/16/25 4:22:22 PM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Director Milano Vincent was granted 12,500 shares, increasing direct ownership by 16% to 89,760 units (SEC Form 4)

      4 - BIOCRYST PHARMACEUTICALS INC (0000882796) (Issuer)

      6/16/25 4:21:59 PM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Director Mckee Amy E was granted 12,500 shares, increasing direct ownership by 45% to 40,331 units (SEC Form 4)

      4 - BIOCRYST PHARMACEUTICALS INC (0000882796) (Issuer)

      6/16/25 4:21:36 PM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $BCRX
    Insider Purchases

    Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • Levin Alan G bought $49,996 worth of shares (7,861 units at $6.36), increasing direct ownership by 21% to 44,951 units (SEC Form 4)

      4 - BIOCRYST PHARMACEUTICALS INC (0000882796) (Issuer)

      5/31/24 4:25:31 PM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Aselage Steve bought $16,000 worth of shares (2,500 units at $6.40) (SEC Form 4)

      4 - BIOCRYST PHARMACEUTICALS INC (0000882796) (Issuer)

      5/29/24 4:16:35 PM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Hutson Nancy J bought $31,900 worth of shares (5,000 units at $6.38), increasing direct ownership by 6% to 86,818 units (SEC Form 4)

      4 - BIOCRYST PHARMACEUTICALS INC (0000882796) (Issuer)

      5/22/24 7:24:51 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $BCRX
    SEC Filings

    See more
    • BioCryst Pharmaceuticals Inc. filed SEC Form 8-K: Entry into a Material Definitive Agreement, Financial Statements and Exhibits

      8-K - BIOCRYST PHARMACEUTICALS INC (0000882796) (Filer)

      6/30/25 7:37:57 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • BioCryst Pharmaceuticals Inc. filed SEC Form 8-K: Other Events, Financial Statements and Exhibits

      8-K - BIOCRYST PHARMACEUTICALS INC (0000882796) (Filer)

      6/27/25 7:10:00 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • BioCryst Pharmaceuticals Inc. filed SEC Form 8-K: Other Events

      8-K - BIOCRYST PHARMACEUTICALS INC (0000882796) (Filer)

      6/25/25 6:57:09 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $BCRX
    Financials

    Live finance-specific insights

    See more
    • BioCryst Reports First Quarter 2025 Financial Results and Provides Business Update

      —Q1 2025 ORLADEYO net revenue of $134.2 million (+51 percent y-o-y)— —Full year 2025 ORLADEYO revenue guidance increased to $580 million to $600 million— —Company now expects to be profitable for full year 2025, a year ahead of schedule— —Company pays down $75 million of debt; saves approximately $23.5 million over life of loan— —NDA submitted for ORLADEYO oral granules for children with HAE aged 2-11— —U.S. IND open for BCX17725 for Netherton syndrome— RESEARCH TRIANGLE PARK, N.C., May 05, 2025 (GLOBE NEWSWIRE) -- BioCryst Pharmaceuticals, Inc. (NASDAQ:BCRX) today reported financial results for the first quarter ended March 31, 2025, and provided a corporate update. "We started 202

      5/5/25 7:00:50 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • BioCryst to Report First Quarter 2025 Financial Results on May 5

      RESEARCH TRIANGLE PARK, N.C., April 21, 2025 (GLOBE NEWSWIRE) -- BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX) today announced that the company will report its first quarter 2025 financial results on Monday, May 5, 2025. BioCryst management will host a conference call and webcast at 8:30 a.m. ET that day to discuss the financial results and provide a corporate update. The live call may be accessed by dialing 1-844-481-2942 for domestic callers and 1-412-317-1866 for international callers. A live webcast and replay of the call will be available online in the investors section of the company website at www.biocryst.com. About BioCryst Pharmaceuticals BioCryst Pharmaceuticals is a global b

      4/21/25 7:00:19 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • BioCryst Reports Fourth Quarter and Full Year 2024 Financial Results and Upcoming Key Milestones

      —ORLADEYO net revenue of $124.2 million for Q4 2024 (+36.6 percent y-o-y) and $437.7 million for FY 2024 (+34.3 percent y-o-y)— —FY 2025 ORLADEYO net revenue guidance increased to between $535-$550 million (previously $515-$535 million)— —GAAP operating loss for full year 2024 was $2.5 million; company achieved $62.9 million non-GAAP operating profit in full year 2024 (not including stock-based compensation), expects to approach positive EPS and positive cash flow in 2H 2025— —Initial clinical data from BCX17725 in Netherton syndrome and avoralstat in diabetic macular edema targeted by end of year— —Company expects to expand ORLADEYO label to children with HAE aged 2 to 11 using oral gra

      2/24/25 7:00:48 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $BCRX
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    See more
    • Cantor Fitzgerald initiated coverage on BioCryst Pharma with a new price target

      Cantor Fitzgerald initiated coverage of BioCryst Pharma with a rating of Overweight and set a new price target of $20.00

      4/29/25 8:10:45 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Wedbush initiated coverage on BioCryst Pharma with a new price target

      Wedbush initiated coverage of BioCryst Pharma with a rating of Outperform and set a new price target of $15.00

      2/25/25 8:02:33 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • JP Morgan resumed coverage on BioCryst Pharma with a new price target

      JP Morgan resumed coverage of BioCryst Pharma with a rating of Overweight and set a new price target of $10.00

      11/20/23 7:20:41 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $BCRX
    Leadership Updates

    Live Leadership Updates

    See more
    • BioCryst Appoints Steve Frank to Board of Directors

      RESEARCH TRIANGLE PARK, N.C., May 01, 2025 (GLOBE NEWSWIRE) -- BioCryst Pharmaceuticals, Inc. (NASDAQ:BCRX) today announced that the company has appointed healthcare investment banking leader Steve Frank to its board of directors. Mr. Frank serves as chairman of global healthcare investment banking at J.P. Morgan. He was previously global group head of worldwide healthcare investment banking at Bear Stearns before it was acquired by J.P. Morgan in 2008. Mr. Frank is a trusted corporate advisor, supporting countless transactions including pharmaceutical, biotechnology, medical device and healthcare services firms. A standout institutional investor before becoming a banker, Mr. Frank direct

      5/1/25 7:00:20 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • BioCryst Appoints Dr. Donald Fong Chief Medical Officer

      RESEARCH TRIANGLE PARK, N.C., Sept. 05, 2024 (GLOBE NEWSWIRE) -- BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX) today announced that Donald S. Fong, MD, MPH, has been appointed as the company's new chief medical officer, effective immediately. Dr. Fong joins Dr. Helen Thackray, the company's chief research and development officer, and Dr. Bill Sheridan, the company's chief development officer, as physicians on the company's leadership team. "We continue to advance our pipeline of novel therapies to treat diseases with significant unmet needs, including programs in Netherton syndrome and diabetic macular edema that we expect will enter the clinic this year and next year, respectively. Dona

      9/5/24 7:00:00 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • BioCryst Appoints Dr. Nancy Hutson as Chair of the Board

      RESEARCH TRIANGLE PARK, N.C., March 31, 2023 (GLOBE NEWSWIRE) -- BioCryst Pharmaceuticals, Inc. (NASDAQ:BCRX) today announced the appointment of Dr. Nancy Hutson as chair of its board of directors, effective immediately. "I am honored to succeed Bob Ingram. He was a model of effective board leadership for us. Our board is comprised of exceptional people with diverse experience and I am excited to continue working alongside them and the management team to deliver innovative new therapies to patients with rare diseases," said Dr. Hutson. Dr. Hutson was appointed to the board in January 2012, bringing over 30 years of experience as a seasoned professional and leader within the pharmaceutica

      3/31/23 7:00:00 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $BCRX
    Press Releases

    Fastest customizable press release news feed in the world

    See more
    • BioCryst Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

      RESEARCH TRIANGLE PARK, N.C., July 03, 2025 (GLOBE NEWSWIRE) -- BioCryst Pharmaceuticals, Inc. (NASDAQ:BCRX) today announced that the compensation committee of BioCryst's board of directors granted eight newly-hired employees restricted stock units (RSUs) covering an aggregate of 57,000 shares of BioCryst common stock. The RSUs were granted as of July 1, 2025, as inducements material to each employee entering into employment with BioCryst. The RSUs were granted in accordance with Nasdaq Listing Rule 5635(c)(4). The RSUs vest in four equal annual installments beginning on the one-year anniversary of the grant date, in each case subject to the new employee's continued service with the compa

      7/3/25 7:00:05 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • BioCryst Announces Sale of European ORLADEYO® (berotralstat) Business to Neopharmed Gentili for up to $264 Million

      —Neopharmed Gentili will pay BioCryst $250 million upfront for the European assets and rights related to ORLADEYO, and up to $14 million in future milestones— —BioCryst plans to use proceeds to retire all remaining term debt, which will eliminate approximately $70 million of future interest payments over remaining life of the loan— —With this transaction, BioCryst expects to end 2027 with approximately $700 million in cash and no term debt (an increase of $400 million from prior 2027 net cash guidance)— RESEARCH TRIANGLE PARK, N.C., June 27, 2025 (GLOBE NEWSWIRE) -- BioCryst Pharmaceuticals, Inc. (NASDAQ:BCRX) today announced that it has entered into a definitive agreement to sell its E

      6/27/25 7:00:12 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • BioCryst Presents New Data on the Long-term Efficacy and Safety of ORLADEYO® (berotralstat) Across all Ages at EAACI

      —Data across pediatric, adolescent, and adult populations demonstrate sustained reductions in HAE attacks and consistent safety profile— —Patients report improved quality of life and daily functioning with ORLADEYO— RESEARCH TRIANGLE PARK, N.C., June 16, 2025 (GLOBE NEWSWIRE) -- BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX) today announced new data on the long-term efficacy and safety of ORLADEYO® (berotralstat) for the prophylactic treatment of hereditary angioedema (HAE) in patients across all age groups. "These data from both clinical trials and real-world settings continue to strengthen the evidence that ORLADEYO is an effective and well-tolerated long-term p

      6/16/25 7:00:00 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $BCRX
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    See more
    • Amendment: SEC Form SC 13G/A filed by BioCryst Pharmaceuticals Inc.

      SC 13G/A - BIOCRYST PHARMACEUTICALS INC (0000882796) (Subject)

      11/7/24 10:52:17 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Amendment: SEC Form SC 13G/A filed by BioCryst Pharmaceuticals Inc.

      SC 13G/A - BIOCRYST PHARMACEUTICALS INC (0000882796) (Subject)

      11/7/24 10:25:46 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Amendment: SEC Form SC 13G/A filed by BioCryst Pharmaceuticals Inc.

      SC 13G/A - BIOCRYST PHARMACEUTICALS INC (0000882796) (Subject)

      11/4/24 11:18:36 AM ET
      $BCRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care