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    SEC Form SC 13G/A filed by CinCor Pharma Inc. (Amendment)

    9/26/22 4:18:49 PM ET
    $CINC
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $CINC alert in real time by email
    SC 13G/A 1 brhc10042253_sc13ga.htm SC 13G/A
    UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
    WASHINGTON, D.C. 20549

    SCHEDULE 13G
    Under the Securities Exchange Act of 1934
    (Amendment No. 1)*

    CinCor Pharma, Inc.

    (Name of Issuer)

    Common stock, $0.00001 par value per share

    (Title of Class of Securities)

    17240Y109

    (CUSIP Number)

    January 11, 2022**

    (Date of Event Which Requires Filing of this Statement)

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

    ☐ Rule 13d-1(b)
     
    ☒ Rule 13d-1(c)
     
    ☐ Rule 13d-1(d)
     
    * The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

    The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

    ** This Amendment No. 1 is being filed solely to remove Aaron Royston as a Reporting Person, because Mr. Royston does not beneficially own any of the Shares reported herein.

    Continued on following pages
    Page 1 of 10 Pages
    Exhibit Index: Page 10



    SCHEDULE 13G
    CUSIP No. 17240Y109
    Page 2 of 10 Pages
    1
    NAMES OF REPORTING PERSONS
     
     
    venBio Global Strategic Fund III, L.P.
     
     
     
     
    2
    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
       
    (a)☐
       
    (b)☐
     
     
    3
    SEC USE ONLY
     
     
     
     
     
     
     
    4
    CITIZENSHIP OR PLACE OF ORGANIZATION
     
     
    Cayman Islands
     
     
     
     
    NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
    5
    SOLE VOTING POWER
     
     
    0
     
     
     
     
    6
    SHARED VOTING POWER
     
     
    1,862,256
     
     
     
     
    7
    SOLE DISPOSITIVE POWER
     
     
    0
     
     
     
     
    8
    SHARED DISPOSITIVE POWER
     
     
    1,862,256
     
     
     
     
    9
    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     
     
    1,862,256
     
     
     
     
    10
    CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
     
     
    ☐
     
     
     
     
    11
    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     
     
    4.9%
     
     
     
     
    12
    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
     
     
    PN
     
     
     
     


    SCHEDULE 13G
    CUSIP No. 17240Y109
    Page 3 of 10 Pages
    1
    NAMES OF REPORTING PERSONS
     
     
    venBio Global Strategic GP III, L.P.
     
     
     
     
    2
    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
       
    (a)☐
       
    (b)☐
     
     
    3
    SEC USE ONLY
     
     
     
     
     
     
     
    4
    CITIZENSHIP OR PLACE OF ORGANIZATION
     
     
    Cayman Islands
     
     
     
     
    NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
    5
    SOLE VOTING POWER
     
     
    0
     
     
     
     
    6
    SHARED VOTING POWER
     
     
    1,862,256
     
     
     
     
    7
    SOLE DISPOSITIVE POWER
     
     
    0
     
     
     
     
    8
    SHARED DISPOSITIVE POWER
     
     
    1,862,256
     
     
     
     
    9
    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     
     
    1,862,256
     
     
     
     
    10
    CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
     
     
    ☐
     
     
     
     
    11
    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     
     
    4.9%
     
     
     
     
    12
    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
     
     
    PN, HC
     
     
     
     


    SCHEDULE 13G
    CUSIP No. 17240Y109
    Page 4 of 10 Pages
    1
    NAMES OF REPORTING PERSONS
     
     
    venBio Global Strategic GP III, Ltd.
     
     
     
     
    2
    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
       
    (a)☐
       
    (b)☐
     
     
    3
    SEC USE ONLY
     
     
     
     
     
     
     
    4
    CITIZENSHIP OR PLACE OF ORGANIZATION
     
     
    Cayman Islands
     
     
     
     
    NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
    5
    SOLE VOTING POWER
     
     
    0
     
     
     
     
    6
    SHARED VOTING POWER
     
     
    1,862,256
     
     
     
     
    7
    SOLE DISPOSITIVE POWER
     
     
    0
     
     
     
     
    8
    SHARED DISPOSITIVE POWER
     
     
    1,862,256
     
     
     
     
    9
    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     
     
    1,862,256
     
     
     
     
    10
    CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
     
     
    ☐
     
     
     
     
    11
    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     
     
    4.9%
     
     
     
     
    12
    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
     
     
    CO, HC
     
     
     
     
     

    SCHEDULE 13G
    CUSIP No. 17240Y109
    Page 5 of 10 Pages
    1
    NAMES OF REPORTING PERSONS
     
     
    Robert Adelman
     
     
     
     
    2
    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
       
    (a)☐
       
    (b)☐
     
     
    3
    SEC USE ONLY
     
     
     
     
     
     
     
    4
    CITIZENSHIP OR PLACE OF ORGANIZATION
     
     
    United States of America
     
     
     
     
    NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
    5
    SOLE VOTING POWER
     
     
    0
     
     
     
     
    6
    SHARED VOTING POWER
     
     
    1,862,256
     
     
     
     
    7
    SOLE DISPOSITIVE POWER
     
     
    0
     
     
     
     
    8
    SHARED DISPOSITIVE POWER
     
     
    1,862,256
     
     
     
     
    9
    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     
     
    1,862,256
     
     
     
     
    10
    CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
     
     
    ☐
     
     
     
     
    11
    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     
     
    4.9%
     
     
     
     
    12
    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
     
     
    IN, HC
     
     
     
     


    SCHEDULE 13G
    CUSIP No. 17240Y109
    Page 6 of 10 Pages
    1
    NAMES OF REPORTING PERSONS
     
     
    Corey Goodman
     
     
     
     
    2
    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
       
    (a)☐
       
    (b)☐
     
     
    3
    SEC USE ONLY
     
     
     
     
     
     
     
    4
    CITIZENSHIP OR PLACE OF ORGANIZATION
     
     
    United States of America
     
     
     
     
    NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
    5
    SOLE VOTING POWER
     
     
    0
     
     
     
     
    6
    SHARED VOTING POWER
     
     
    1,862,256
     
     
     
     
    7
    SOLE DISPOSITIVE POWER
     
     
    0
     
     
     
     
    8
    SHARED DISPOSITIVE POWER
     
     
    1,862,256
     
     
     
     
    9
    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     
     
    1,862,256
     
     
     
     
    10
    CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
     
     
    ☐
     
     
     
     
    11
    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
     
     
    4.9%
     
     
     
     
    12
    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
     
     
    IN, HC
     
     
     
     


    SCHEDULE 13G
    CUSIP No. 17240Y109
    Page 7 of 10 Pages
    Explanatory Note:

    This Amendment No. 1 is being filed solely to remove Aaron Royston as a Reporting Person, because Mr. Royston does not beneficially own any of the Shares reported herein.  Mr. Royston was inadvertently included as a Reporting Person in the Schedule 13G originally filed by the Reporting Persons on January 11, 2022.

    Item 1(a).
    Name of Issuer

    CinCor Pharma, Inc. (the “Issuer”)

    Item 1(b).
    Address of Issuer’s Principal Executive Offices

    230 Third Avenue, 6th Floor, Waltham, MA 02451

    Item 2(a).
    Names of Persons Filing

    This Statement is filed on behalf of the following persons (collectively, the “Reporting Persons”):


    i.
    venBio Global Strategic Fund III, L.P. (“Fund III”);

    ii.
    venBio Global Strategic GP III, L.P. (the “General Partner III);

    iii.
    venBio Global Strategic GP III, Ltd. (“GP Ltd. III”);

    iv.
    Robert Adelman (“Mr. Adelman”); and

    v.
    Corey Goodman (“Mr. Goodman”);

    This Statement relates to Shares (as defined herein) directly beneficially owned by Fund III. General Partner III is the sole general partner of Fund III, and GP Ltd. III is the sole general partner of General Partner III. Mr. Adelman and Mr. Goodman are directors of GP Ltd. III (collectively, the “Directors”). Accordingly, each of General Partner III, GP Ltd. III, and the Directors may be deemed to indirectly beneficially own the Shares reported herein.

    Item 2(b).
    Address of Principal Business Office or, if None, Residence

    The address of the principal business office of each Reporting Person is c/o venBio Partners, LLC, 1700 Owens Street, Suite 595, San Francisco, CA 94158.

    Item 2(c).
    Citizenship

    Each of Fund III and General Partner III is a Cayman Islands exempted limited partnership. GP Ltd. III is a Cayman Islands exempted company. Each of the Directors is a citizen of the United States of America.

    Item 2(d).
    Title of Class of Securities

    Common stock, $0.00001 par value per share (the “Shares”)

    Item 2(e).
    CUSIP Number

    17240Y109

    Item 3.
    If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

    This Item 3 is not applicable.


    SCHEDULE 13G
    CUSIP No. 17240Y109
    Page 8 of 10 Pages
    Item 4.
    Ownership
    Item 4(a)
    Amount Beneficially Owned

    As of and the date hereof, each of the Reporting Persons may be deemed to beneficially own 1,862,256 Shares.

    As of January 11, 2022, the date of the original Schedule 13G, each of the Reporting Persons may have been deemed to beneficially own 1,980,706 Shares.

    Item 4(b)
    Percent of Class

    The percentages set forth in row 11 are based on 37,739,323 Shares outstanding, as reported in the Issuer’s quarterly report on Form 10-Q, filed with the SEC on August 8, 2022.

    As of January 11, 2022, the Reporting Persons’ beneficial ownership percentage of 5.6%, which was set forth in the original Schedule 13G, was based on 35,419,099 Shares expected to be outstanding upon closing of the Issuer’s initial public offering on January 11, 2022, as reported in the Issuer’s registration statement on Form S-1, file number 333-261738.

    Item 4(c)
    Number of shares as to which such person has:


    (i)
    sole power to vote or to direct the vote: See Line 5 of cover sheets.

    (ii)
    shared power to vote or to direct the vote: See Line 6 of cover sheets.

    (iii)
    sole power to dispose or to direct the disposition of: See Line 7 of cover sheets.

    (iv)
    shared power to dispose or to direct the disposition of: See Line 8 of cover sheets.
     
    Each Reporting Person disclaims beneficial ownership of such securities except for the shares, if any, such Reporting Person holds of record.

    Item 5.
    Ownership of Five Percent or Less of a Class

    If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than 5 percent of the class of securities, check the following [X].

    Item 6.
    Ownership of More than Five Percent on Behalf of Another Person

    This Item 6 is not applicable.

    Item 7.
    Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person

    See disclosure in Item 2 hereof.

    Item 8.
    Identification and Classification of Members of the Group

    This Item 8 is not applicable.

    Item 9.
    Notice of Dissolution of Group

    This Item 9 is not applicable.

    Item 10.
    Certification

    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.


    SCHEDULE 13G
    CUSIP No. 17240Y109
    Page 9 of 10 Pages
    SIGNATURES

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

    Dated: September 26, 2022
       
     
    VENBIO GLOBAL STRATEGIC FUND III, L.P.
     
     
    By:
    VENBIO GLOBAL STRATEGIC GP III, L.P.
    General Partner
     
     
    By:
    VENBIO GLOBAL STRATEGIC GP III, LTD.
    General Partner
     
     
    By:
    *
     
     
    Title:
    Director
     
     
    By:
    *
     
     
    Title:
    Director
     
     
    By:
    *
     
     
    Title:
    Director
     
     
    VENBIO GLOBAL STRATEGIC GP III, L.P.
     
     
    By:
    VENBIO GLOBAL STRATEGIC GP III, LTD.
    General Partner
     
     
    By:
    *
     
     
    Title:
    Director
     
     
    By:
    *
     
     
    Title:
    Director
     
     
    By:
    *
     
     
    Title:
    Director
     
     
    VENBIO GLOBAL STRATEGIC GP III, LTD.
     
     
    By:
    *
     
     
    Title:
    Director
     
     
    By:
    *
     
     
    Title:
    Director
     
     
    By:
    *
     
     
    Title:
    Director
     

     
    *
     
     
    Corey Goodman
     
       *  
     
    Robert Adelman
     
     
    By:
    /s/ David Pezeshki
     
       
    David Pezeshki
     
       
    As attorney-in-fact
     

    This Schedule 13D was executed by David Pezeshki on behalf of the individuals listed above pursuant to a Power of Attorney, a copy of which is attached as Exhibit 2.


    SCHEDULE 13G
    CUSIP No. 17240Y109
    Page 10 of 10 Pages
    EXHIBIT INDEX

    Ex.
     
    Page No.
     
     
     
    1
    Joint Filing Agreement
    11
     


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      Primary endpoint in Intention to Treat (ITT) was not met despite large absolute reductions in Systolic Blood Pressure (SBP) 12.6 mmHg placebo-adjusted reduction in SBP with 2 mg baxdrostat in a pre-specified subgroup that represents approximately 81-89% of the U.S. hypertension population (nominal p-value = 0.001) Safety profile and tolerability consistent with BrigHtn Phase 2 data; no patient discontinued due to treatment-related adverse events; low hyperkalemia incidence HALO in combination with BrigHtn informs the dose and study populations anticipated to be recruited into Phase 3 trials pending confirmation by FDA at planned end of Phase 2 meeting in January 2023; Phase 3 trials expec

      11/28/22 7:30:00 AM ET
      $CINC
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • CinCor Pharma Announces Late-Breaking Presentation of Phase 2 BrigHtn Data on Baxdrostat in Treatment-Resistant Hypertension at the 2022 American Heart Association Scientific Sessions

      Aldosterone and renin biomarker activity clinically demonstrate how baxdrostat mechanistically achieves selective blood pressure lowering effects with no impact on cortisol 20.3 mmHg reduction in systolic blood pressure, or 11 mmHg (p-value < 0.0001) placebo-adjusted decline at the 2 mg dose Well-tolerated profile and differentiated mechanism of action supports combination approaches Conference call and live webcast Tuesday November 8th, 2022 at 7 AM Eastern Time WALTHAM, Mass., Nov. 07, 2022 (GLOBE NEWSWIRE) -- CinCor Pharma, Inc. ("CinCor") announced the presentation today of Phase 2 data from its BrigHtn trial as part of the late-breaking science session at the 2022 American Heart A

      11/7/22 5:09:52 PM ET
      $CINC
      Biotechnology: Pharmaceutical Preparations
      Health Care