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    SEC Form SC 13G/A filed by Mirum Pharmaceuticals Inc. (Amendment)

    5/3/23 4:58:32 PM ET
    $MIRM
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $MIRM alert in real time by email
    SC 13G/A 1 e618579_sc13ga-mirum.htm

     

    SECURITIES AND EXCHANGE COMMISSION

    WASHINGTON, DC 20549

     

    SCHEDULE 13G

    (Rule 13d-102)

     

    INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT

    TO RULES 13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED

    PURSUANT TO RULE 13d-2(b)

     

    (Amendment No. 5) *

     

    Mirum Pharmaceuticals, Inc.

    (Name of Issuer)

     

    Common Stock

    (Title of Class of Securities)

     

    604749101

    (CUSIP Number)

     

    May 3, 2023

    (Date of Event Which Requires Filing of this Statement)

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

      

    ☐Rule 13d-1(b)

     

    ☒Rule 13d-1(c)

     

    ☐Rule 13d-1(d)

     

    (Page 1 of 12 Pages)

     

    ----------

    * The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

     

    The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

       

    CUSIP No. 604749101 13G Page 2 of 12 Pages

     

    1.

    NAME OF REPORTING PERSONS

    I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

     

    Deerfield Management Company, L.P.

    2.

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

     

     

    (a) ☐

    (b) ☒

    3.

    SEC USE ONLY

     

     

    4.

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

     NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

    5.

    SOLE VOTING POWER

     

    0

     
    6.

    SHARED VOTING POWER

     

    0

     

    7.

     

    SOLE DISPOSITIVE POWER

     

    0

     

    8.

     

    SHARED DISPOSITIVE POWER

     

    0

     

    9.

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    0

    10.

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*

     

     

    ☐

    11.

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    0.00%

    12.

    TYPE OF REPORTING PERSON*

     

    PN

     

        

    CUSIP No. 604749101 13G Page 3 of 12 Pages

     

    1.

    NAME OF REPORTING PERSONS

    I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

     

    Deerfield Mgmt HIF, L.P.

    2.

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

     

     

    (a) ☐

    (b) ☒

    3.

    SEC USE ONLY

     

     

    4.

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

     NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

    5.

    SOLE VOTING POWER

     

    0

     
    6.

    SHARED VOTING POWER

     

    0

     

    7.

     

    SOLE DISPOSITIVE POWER

     

    0

     

    8.

     

    SHARED DISPOSITIVE POWER

     

    0

     

    9.

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    0

    10.

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*

     

     

    ☐

    11.

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    0.00%

    12.

    TYPE OF REPORTING PERSON*

     

    PN

     

     

    CUSIP No. 604749101 13G Page 4 of 12 Pages

     

    1.

    NAME OF REPORTING PERSONS

    I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

     

    Deerfield Healthcare Innovations Fund, L.P.

    2.

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

     

     

    (a) ☐

    (b) ☒

    3.

    SEC USE ONLY

     

     

    4.

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

     NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

    5.

    SOLE VOTING POWER

     

    0

     
    6.

    SHARED VOTING POWER

     

    0

     

    7.

     

    SOLE DISPOSITIVE POWER

     

    0

     

    8.

     

    SHARED DISPOSITIVE POWER

     

    0

     

    9.

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    0

    10.

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*

     

     

    ☐

    11.

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    0.00%

    12.

    TYPE OF REPORTING PERSON*

     

    PN 

     

    CUSIP No. 604749101 13G Page 5 of 12 Pages

     

    1.

    NAME OF REPORTING PERSONS

    I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

     

    Deerfield Mgmt IV, L.P.

    2.

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

     

     

    (a) ☐

    (b) ☒

    3.

    SEC USE ONLY

     

     

    4.

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

     NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

    5.

    SOLE VOTING POWER

     

    0

     
    6.

    SHARED VOTING POWER

     

    0

     

    7.

     

    SOLE DISPOSITIVE POWER

     

    0

     

    8.

     

    SHARED DISPOSITIVE POWER

     

    0

     

    9.

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    0

    10.

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*

     

     

    ☐

    11.

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    0.00%

    12.

    TYPE OF REPORTING PERSON*

     

    PN

     

      

    CUSIP No. 604749101 13G Page 6 of 12 Pages

     

    1.

    NAME OF REPORTING PERSONS

    I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

     

    Deerfield Private Design Fund IV, L.P.

    2.

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

     

     

    (a) ☐

    (b) ☒

    3.

    SEC USE ONLY

     

     

    4.

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

     NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

    5.

    SOLE VOTING POWER

     

    0

     
    6.

    SHARED VOTING POWER

     

    0

     

    7.

     

    SOLE DISPOSITIVE POWER

     

    0

     

    8.

     

    SHARED DISPOSITIVE POWER

     

    0

     

    9.

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    0

    10.

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*

     

     

    ☐

    11.

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    0.00%

    12.

    TYPE OF REPORTING PERSON*

     

    PN

     

    CUSIP No. 604749101 13G Page 7 of 12 Pages

     

    1.

    NAME OF REPORTING PERSONS

    I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

     

    James E. Flynn

    2.

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

     

     

    (a) ☐

    (b) ☒

    3.

    SEC USE ONLY

     

     

    4.

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    United States

     

     

     NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

    5.

    SOLE VOTING POWER

     

    0

     
    6.

    SHARED VOTING POWER

     

    0

     

    7.

     

    SOLE DISPOSITIVE POWER

     

    0

     

    8.

     

    SHARED DISPOSITIVE POWER

     

    0

     

    9.

     

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    0

    10.

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*

     

     

    ☐

    11.

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    0.00%

    12.

    TYPE OF REPORTING PERSON*

     

    IN

     

      

    CUSIP No. 604749101 13G Page 8 of 12 Pages

     

    Item 1(a). Name of Issuer:
       
     

    Mirum Pharmaceuticals, Inc.

       
    Item 1(b). Address of Issuer's Principal Executive Offices:
       
     

    950 Tower Lane, Suite 1050

    Foster City, California 94404

       
    Item 2(a). Name of Person Filing:
       
     

    James E. Flynn, Deerfield Mgmt IV, L.P., Deerfield Mgmt HIF, L.P., Deerfield Management Company, L.P., Deerfield Healthcare Innovations Fund, L.P. and Deerfield Private Design Fund IV, L.P.

       
    Item 2(b). Address of Principal Business Office, or if None, Residence:
       
     

    James E. Flynn, Deerfield Mgmt IV, L.P., Deerfield Mgmt HIF, L.P., Deerfield Management Company, L.P., Deerfield Healthcare Innovations Fund, L.P. and Deerfield Private Design Fund IV, L.P., 345 Park Avenue South, 12th Floor, New York, NY 10010

       
    Item 2(c). Citizenship:
       
     

    Deerfield Management Company, L.P., Deerfield Mgmt IV, L.P., Deerfield Mgmt HIF, L.P., Deerfield Healthcare Innovations Fund, L.P. and Deerfield Private Design Fund IV, L.P. - Delaware limited partnerships;

     

    James E. Flynn – United States citizen

       
    Item 2(d). Title of Class of Securities:
       
     

    Common Stock

       
    Item 2(e). CUSIP Number:
       
     

    604749101

         
    Item 3.

    If This Statement is Filed Pursuant to Rule 13d-1(b), or 13d-2(b) or (c), Check Whether the Person Filing is a:

       
    (a) ☐

    Broker or dealer registered under Section 15 of the Exchange Act.

         
    (b) ☐ Bank as defined in Section 3(a)(6) of the Exchange Act.
         
    (c) ☐

    Insurance company as defined in Section 3(a)(19) of the Exchange Act.

         
    (d) ☐

    Investment company registered under Section 8 of the Investment Company Act.

         
    (e) ☐ An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E);

     

    CUSIP No. 604749101 13G Page 9 of 12 Pages

     

         
    (f) ☐

    An employee benefit plan or endowment fund in accordance with Rule 13d-1(b)(1)(ii)(F);

         
    (g) ☐

    A parent holding company or control person in accordance with Rule 13d-1(b)(1)(ii)(G);

         

    (h)

    ☐

    A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act;

         
    (i) ☐

    A church plan that is excluded from the definition of an investment company under Section 3(c)(14) of the Investment Company Act;

         
    (j) ☐ A non-U.S. institution in accordance with Rule 13d-1(b)(1)(ii)(J);
         
    (k) ☐ Group, in accordance with Rule 13d-1(b)(1)(ii)(K).

     

    If filing as a non-U.S. institution in accordance with Rule 13d-1(b)(1)(ii)(J), please specify the type of institution: _________________

     

    Item 4. Ownership.
           

    Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1.

           
    (a) Amount beneficially owned**:  
           
     

    Deerfield Management Company, L.P. - 0 shares

    Deerfield Mgmt IV, L.P. – 0 shares

    Deerfield Mgmt HIF, L.P. - 0 shares

    Deerfield Healthcare Innovations Fund, L.P. - 0 shares

    Deerfield Private Design Fund IV, L.P. - 0 shares

    James E. Flynn – 0 shares 

           
    (b) Percent of class**:  
           
     

    Deerfield Management Company, L.P. – 0.00%

    Deerfield Mgmt IV, L.P. – 0.00%

    Deerfield Mgmt HIF, L.P. – 0.00%

    Deerfield Healthcare Innovations Fund, L.P. – 0.00%

    Deerfield Private Design Fund IV, L.P. – 0.00%

    James E. Flynn – 0.00% 

           
    (c) Number of shares as to which such person has**:  
           
      (i) Sole power to vote or to direct the vote: All Reporting Persons - 0
           
      (ii) Shared power to vote or to direct the vote:

    Deerfield Management Company, L.P. - 0

    Deerfield Mgmt IV, L.P. – 0

    Deerfield Mgmt HIF, L.P. - 0

    Deerfield Healthcare Innovations Fund, L.P. - 0

    Deerfield Private Design Fund IV, L.P. - 0

    James E. Flynn – 0

     

    CUSIP No. 604749101 13G Page 10 of 12 Pages

     

           
      (iii)

    Sole power to dispose or to direct the disposition of:

    All Reporting Persons - 0
           
      (iv)

    Shared power to dispose or to direct the disposition of:

    Deerfield Management Company, L.P. - 0

    Deerfield Mgmt IV, L.P. – 0

    Deerfield Mgmt HIF, L.P. - 0

    Deerfield Healthcare Innovations Fund, L.P. - 0

    Deerfield Private Design Fund IV, L.P. - 0

    James E. Flynn – 0

      

    **See footnotes on cover pages which are incorporated by reference herein.

      

    Item 5. Ownership of Five Percent or Less of a Class.
       

    If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities check the following ☒.

       
     
       
    Item 6. Ownership of More Than Five Percent on Behalf of Another Person.
       

    If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than five percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required.

       
      N/A
       
    Item 7.

    Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.

       

    If a parent holding company or Control person has filed this schedule, pursuant to Rule 13d-1(b)(1)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company or control person has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary.

       
      N/A
       
    Item 8. Identification and Classification of Members of the Group.
       

    If a group has filed this schedule pursuant to ss.240.13d-1(b)(1)(ii)(J), so indicate under Item 3(j) and attach an exhibit stating the identity and Item 3 classification of each member of the group. If a group has filed this schedule pursuant to ss.240.13d-1(c) or ss.240.13d-1(d), attach an exhibit stating the identity of each member of the group.

       
      See Exhibit B

     

    CUSIP No. 604749101 13G Page 11 of 12 Pages

     

       
    Item 9. Notice of Dissolution of Group.
       

    Notice of dissolution of a group may be furnished as an exhibit stating the date of the dissolution and that all further filings with respect to transactions in the security reported on will be filed, if required, by members of the group, in their individual capacity. See Item 5.

       
      N/A
       
    Item 10. Certifications.
       

    "By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under §240.14a–11."

     

    CUSIP No. 604749101 13G Page 12 of 12 Pages

     

    SIGNATURE

     

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     

    DEERFIELD MANAGEMENT COMPANY, L.P.

    By: Flynn Management LLC, General Partner

     

    By: /s/ Jonathan Isler

           Jonathan Isler, Attorney-In-Fact

     

     

    DEERFIELD MGMT IV, L.P.

    By: J.E. Flynn Capital IV, LLC, General Partner

     

    By: /s/ Jonathan Isler

           Jonathan Isler, Attorney-In-Fact

     

     

    DEERFIELD PRIVATE DESIGN FUND IV, L.P.

    By: Deerfield Mgmt IV, L.P., General Partner

    By: J.E. Flynn Capital IV, LLC, General Partner

     

    By: /s/ Jonathan Isler

           Jonathan Isler, Attorney-In-Fact

     

     

    DEERFIELD MGMT HIF, L.P.

    By: J.E. Flynn Capital HIF, LLC, General Partner

     

    By: /s/ Jonathan Isler

           Jonathan Isler, Attorney-In-Fact

     

     

    DEERFIELD HEALTHCARE INNOVATIONS FUND, L.P.

    By: Deerfield Mgmt HIF, L.P., General Partner

    By: J.E. Flynn Capital HIF, LLC, General Partner

     

    By: /s/ Jonathan Isler

           Jonathan Isler, Attorney-In-Fact

     

     

    JAMES E. FLYNN

     

    /s/ Jonathan Isler

    Jonathan Isler, Attorney-In-Fact

     

    Date: May 3, 2023

     

     

     

     

    Exhibit List

     

    Exhibit A. Joint Filing Agreement.

     

    Exhibit B. Item 8 Statement.

     

    Exhibit C. Power of Attorney (1).

     

    (1) Power of Attorney previously filed as Exhibit 24 to a Form 4 with regard to DA32 Life Science Tech Acquisition Corp. filed with the Securities and Exchange Commission on August 3, 2021 by Deerfield Partners, L.P., Deerfield Mgmt, L.P., Deerfield Management Company, L.P. and James E. Flynn.

     

     

     

     

    Exhibit A

     

    Joint Filing Agreement

     

    The undersigned agree that this Schedule 13G, and all amendments thereto, relating to the Common Stock of Mirum Pharmaceuticals, Inc. shall be filed on behalf of the undersigned.

     

    DEERFIELD MANAGEMENT COMPANY, L.P.

    By: Flynn Management LLC, General Partner

     

    By: /s/ Jonathan Isler

           Jonathan Isler, Attorney-In-Fact

     

     

    DEERFIELD MGMT IV, L.P.

    By: J.E. Flynn Capital IV, LLC, General Partner

     

    By: /s/ Jonathan Isler

           Jonathan Isler, Attorney-In-Fact

     

     

    DEERFIELD PRIVATE DESIGN FUND IV, L.P.

    By: Deerfield Mgmt IV, L.P., General Partner

    By: J.E. Flynn Capital IV, LLC, General Partner

     

    By: /s/ Jonathan Isler

           Jonathan Isler, Attorney-In-Fact

     

     

    DEERFIELD MGMT HIF, L.P.

    By: J.E. Flynn Capital HIF, LLC, General Partner

     

    By: /s/ Jonathan Isler

           Jonathan Isler, Attorney-In-Fact

     

     

    DEERFIELD HEALTHCARE INNOVATIONS FUND, L.P.

    By: Deerfield Mgmt HIF, L.P., General Partner

    By: J.E. Flynn Capital HIF, LLC, General Partner

     

    By: /s/ Jonathan Isler

           Jonathan Isler, Attorney-In-Fact

     

     

    JAMES E. FLYNN 

     

    /s/ Jonathan Isler

    Jonathan Isler, Attorney-In-Fact

     

     

     

     

    Exhibit B

     

    Due to the relationships between them, the reporting persons hereunder may be deemed to constitute a “group” with one another for purposes of Section 13(d)(3) of the Securities Exchange Act of 1934.

     

     

     

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    $MIRM
    Insider Purchases

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    Director Heron Patrick J acquired 159,277 shares and bought $8,999,984 worth of shares (131,425 units at $68.48) (SEC Form 4)

    4 - Mirum Pharmaceuticals, Inc. (0001759425) (Issuer)

    1/27/26 4:14:26 PM ET
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    Biotechnology: Pharmaceutical Preparations
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    Director Heron Patrick J bought $24,214 worth of shares (549 units at $44.11) (SEC Form 4)

    4 - Mirum Pharmaceuticals, Inc. (0001759425) (Issuer)

    3/18/25 5:04:31 PM ET
    $MIRM
    Biotechnology: Pharmaceutical Preparations
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    Director Heron Patrick J bought $99,518 worth of shares (2,298 units at $43.31) (SEC Form 4)

    4 - Mirum Pharmaceuticals, Inc. (0001759425) (Issuer)

    3/12/25 4:51:20 PM ET
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    Biotechnology: Pharmaceutical Preparations
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    SEC Filings

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    SEC Form 144 filed by Mirum Pharmaceuticals Inc.

    144 - Mirum Pharmaceuticals, Inc. (0001759425) (Subject)

    2/2/26 8:25:39 PM ET
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    Biotechnology: Pharmaceutical Preparations
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    SEC Form 144 filed by Mirum Pharmaceuticals Inc.

    144 - Mirum Pharmaceuticals, Inc. (0001759425) (Subject)

    2/2/26 8:21:22 PM ET
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    Biotechnology: Pharmaceutical Preparations
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    SEC Form D filed by Mirum Pharmaceuticals Inc.

    D - Mirum Pharmaceuticals, Inc. (0001759425) (Filer)

    1/29/26 4:12:12 PM ET
    $MIRM
    Biotechnology: Pharmaceutical Preparations
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    Mirum Pharmaceuticals Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

    Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM) today announced that on February 10, 2026, the Compensation Committee of Mirum's Board of Directors granted inducement awards consisting of non-qualified stock options to purchase 163,040 shares of common stock, 219,090 restricted stock units ("RSUs"), and 48,880 performance stock units ("PSUs") to 37 new employees under Mirum's 2020 Inducement Plan. The Compensation Committee of Mirum's Board of Directors approved the awards as an inducement material to the new employees' employment in accordance with Nasdaq Listing Rule 5635(c)(4). Each stock option has an exercise price per share equal to $100.91 per share, Mirum's closing trading price on Febr

    2/10/26 10:45:00 PM ET
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    Biotechnology: Pharmaceutical Preparations
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    Mirum Pharmaceuticals Announces Health Canada Authorization of LIVMARLI® Tablet Formulation for the Treatment of Cholestatic Pruritus in Patients with Alagille Syndrome

    - Tablet authorization builds upon established use of LIVMARLI oral solution in Canada Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM), a leading rare disease company, today announced that Health Canada has authorized the tablet formulation of LIVMARLI® (maralixibat) for the treatment of cholestatic pruritus in patients with Alagille syndrome (ALGS). LIVMARLI had previously been authorized in Canada as an oral solution for the treatment of cholestatic pruritus in patients with ALGS aged 12 months or older. The tablet formulation complements the existing 9.5 mg/ml oral solution, offering an additional dosing option for patients with ALGS weighing 22 kg or more who are able to swallow tablets.

    2/5/26 8:51:00 AM ET
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    Biotechnology: Pharmaceutical Preparations
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    Mirum Pharmaceuticals Announces Health Canada Authorization of LIVMARLI® for the Treatment of Cholestatic Pruritus in Patients with Progressive Familial Intrahepatic Cholestasis (PFIC)

    - Authorization includes oral solution and tablet formulation to support flexible dosing Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM), a leading rare disease company, today announced that Health Canada has authorized LIVMARLI® (maralixibat) oral solution and tablet formulation for the treatment of cholestatic pruritus in patients aged 12 months or older with progressive familial intrahepatic cholestasis (PFIC). PFIC is a rare, inherited pediatric liver disease caused by impaired bile flow, leading to the accumulation of bile acids in the liver and bloodstream. Cholestasis in PFIC is associated with severe pruritus that can significantly impede quality of life for patients and caregivers. L

    2/5/26 8:00:00 AM ET
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    Biotechnology: Pharmaceutical Preparations
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    Analyst Ratings

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    TD Cowen initiated coverage on Mirum Pharmaceuticals with a new price target

    TD Cowen initiated coverage of Mirum Pharmaceuticals with a rating of Buy and set a new price target of $95.00

    9/24/25 7:56:41 AM ET
    $MIRM
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Stifel resumed coverage on Mirum Pharmaceuticals with a new price target

    Stifel resumed coverage of Mirum Pharmaceuticals with a rating of Buy and set a new price target of $89.00

    8/11/25 10:05:47 AM ET
    $MIRM
    Biotechnology: Pharmaceutical Preparations
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    H.C. Wainwright resumed coverage on Mirum Pharmaceuticals with a new price target

    H.C. Wainwright resumed coverage of Mirum Pharmaceuticals with a rating of Buy and set a new price target of $73.00

    5/19/25 8:53:13 AM ET
    $MIRM
    Biotechnology: Pharmaceutical Preparations
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    $MIRM
    Leadership Updates

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    Mirum Pharmaceuticals Appoints Doug Sheehy, JD, as Chief Legal Officer

    Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM) today announced the appointment of Doug Sheehy, JD, as chief legal officer. Mr. Sheehy brings nearly two decades of experience leading global legal and compliance operations for biopharmaceutical companies. Mr. Sheehy was most recently chief legal officer and secretary at Sonoma Biotherapeutics, Inc., which is developing regulatory T cell therapies for autoimmune and inflammatory diseases. Prior to Sonoma, from 2016 to 2020, he served as general counsel and secretary for Aimmune Therapeutics, Inc., a biopharmaceutical company that specialized in the development and commercialization of treatments for life-threatening food allergies. Mr. Sheehy serv

    5/19/25 8:30:00 AM ET
    $MIRM
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Mirum Pharmaceuticals Announces Preliminary Unaudited 2024 Net Product Sales and Cash Balance and Provides Corporate Updates

    - 2024 net product sales of approximately $336 million exceeds upper end of guidance range; preliminary and unaudited estimate - 2025 expected global net product sales of $420 million to $435 million - VISTAS study of volixibat in primary sclerosing cholangitis expected to complete enrollment in second half 2025; topline data expected 2026 Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM) today provided its preliminary and unaudited estimates for full-year 2024 net product sales, year-end cash balance, corporate updates, and full-year 2025 outlook. "2024 marked a significant year for Mirum as we accelerated our commercial business and achieved significant development milestones," said Chris

    1/13/25 8:30:00 AM ET
    $MIRM
    Biotechnology: Pharmaceutical Preparations
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    Sagimet Biosciences Announces Appointment of Tim Walbert and Paul Hoelscher to its Board of Directors

    SAN MATEO, Calif., March 25, 2024 (GLOBE NEWSWIRE) -- Sagimet Biosciences Inc. ((Sagimet, NASDAQ:SGMT), a clinical-stage biopharmaceutical company developing novel fatty acid synthase (FASN) inhibitors designed to target dysfunctional metabolic and fibrotic pathways, today announced the appointments of two biotechnology industry leaders, Tim Walbert and Paul Hoelscher, to the board of directors of the Company, effective April 1, 2024. "We are fortunate to have Tim and Paul join us at this key stage as we prepare to initiate a pivotal, Phase 3 trial for our lead candidate denifanstat in MASH in the second half of 2024," said Dave Happel, CEO of Sagimet. "With his experience as CEO of publi

    3/25/24 7:00:00 AM ET
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    Biotechnology: Biological Products (No Diagnostic Substances)
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    Mirum Pharmaceuticals Enters into Definitive Agreement to Acquire Bluejay Therapeutics, Expanding Global Leadership in Rare Disease

    -Planned acquisition of brelovitug for chronic hepatitis delta virus (HDV) with Breakthrough Therapy and PRIME designations -Anticipated to be highly synergistic with Mirum's liver expertise and proven global commercial capabilities -HDV: Large, high unmet-need rare liver disease with no FDA-approved therapies -Top-line Phase 3 results expected in 2H 2026 -Conference call today, December 8, 2025 at 8:30 am ET/5:30 am PT Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM), a leading rare disease company, today announced its entry into a definitive agreement to acquire Bluejay Therapeutics, a privately held biotechnology company focused on viral and liver diseases. The transaction would add worldw

    12/8/25 8:00:00 AM ET
    $MIRM
    Biotechnology: Pharmaceutical Preparations
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    Mirum Pharmaceuticals Reports Third Quarter 2025 Financial Results and Provides Business Update

    - Third quarter 2025 total revenue of $133 million - 2025 revenue guidance updated to $500 to $510 million - Phase 2b VISTAS topline data expected second quarter of 2026 - Conference call to provide business updates today, November 4 at 1:30 p.m. PT / 4:30 p.m. ET Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM) today reported financial results for the third quarter 2025 and provided a business update. "Mirum is well positioned heading into 2026 with strong commercial momentum and multiple upcoming catalysts," said Chris Peetz, Chief Executive Officer of Mirum. "Our third quarter results once again underscore the strength of our commercial medicines with continued strong performance. We also

    11/4/25 4:01:00 PM ET
    $MIRM
    Biotechnology: Pharmaceutical Preparations
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    Mirum Pharmaceuticals to Announce Third Quarter 2025 Financial Results and Host Conference Call on November 4, 2025

    Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM) today announced that it will report third quarter 2025 financial results on November 4, 2025. Mirum will also host a conference call to discuss the third quarter 2025 financial results and recent corporate progress. Conference call details: Tuesday November 4th, 2025 4:30 p.m. ET / 1:30 p.m. PT Dial-In: US/Toll-Free: +1 833 470 1428 International: +1 646 844 6383 Access Code: 299722 You may also access the call via webcast by visiting the Events & Presentations section on Mirum's website. A replay of this webcast will be available for 30 days. About Mirum Pharmaceuticals, Inc. Mirum Pharmaceuticals, Inc. is a biopharmaceutical company dedica

    10/28/25 4:02:00 PM ET
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    Large Ownership Changes

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    Amendment: SEC Form SC 13G/A filed by Mirum Pharmaceuticals Inc.

    SC 13G/A - Mirum Pharmaceuticals, Inc. (0001759425) (Subject)

    11/14/24 4:37:52 PM ET
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    Biotechnology: Pharmaceutical Preparations
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    Amendment: SEC Form SC 13G/A filed by Mirum Pharmaceuticals Inc.

    SC 13G/A - Mirum Pharmaceuticals, Inc. (0001759425) (Subject)

    11/14/24 12:55:40 PM ET
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    Biotechnology: Pharmaceutical Preparations
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    Amendment: SEC Form SC 13G/A filed by Mirum Pharmaceuticals Inc.

    SC 13G/A - Mirum Pharmaceuticals, Inc. (0001759425) (Subject)

    11/14/24 12:25:52 PM ET
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    Biotechnology: Pharmaceutical Preparations
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