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    SEC Form SC 13G/A filed by Pharvaris N.V. (Amendment)

    1/22/24 4:30:25 PM ET
    $PHVS
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $PHVS alert in real time by email
    SC 13G/A 1 d737649dsc13ga.htm SC 13G/A SC 13G/A

     

     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    Washington, DC 20549

     

     

    SCHEDULE 13G

    (Rule 13d-102)

    Information to be Included in Statements Filed Pursuant

    to § 240.13d-1(b), (c) and (d) and Amendments Thereto Filed

    Pursuant to § 240.13d-2

    Under the Securities Exchange Act of 1934

    (Amendment No. 2)

     

     

    PHARVARIS N.V.

    (Name of Issuer)

     

     

    Ordinary Shares, €0.12

    par value per share

    (Title of Class of Securities)

    N69605108

    (CUSIP Number)

    January 18, 2024

    (Date of Event Which Requires Filing of This Statement)

     

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

    ☐ Rule 13d-1(b)

    ☒ Rule 13d-1(c)

    ☐ Rule 13d-1(d)

     

    *

    The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

    The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934, as amended (“Act”), or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

     

     

     


    CUSIP No. N69605108    13G    Page 2 of 8 Pages

     

      1    

      Names of Reporting Persons

     

      Bain Capital Life Sciences Fund, L.P.

      2  

      Check the Appropriate Box if a Member of a Group

     

      (a)  ☐        (b)  ☐

      3  

      SEC Use Only

     

      4  

      Citizenship or Place of Organization

     

      Cayman Islands

    Number of

    Shares

    Beneficially 

    Owned by

    Each

    Reporting

    Person

    With

       5     

      Sole Voting Power

     

      0 Ordinary Shares

       6   

      Shared Voting Power

     

      1,967,093 Ordinary Shares

       7   

      Sole Dispositive Power

     

      0 Ordinary Shares

       8   

      Shared Dispositive Power

     

      1,967,093 Ordinary Shares

      9    

      Aggregate Amount Beneficially Owned by Each Reporting Person

     

      1,967,093 Ordinary Shares

    10  

      Check if the Aggregate Amount in Row (9) Excludes Certain Shares

     

      ☐

    11  

      Percent of Class Represented by Amount in Row 9

     

      3.8%

    12  

      Type of Reporting Person

     

      PN


    CUSIP No. N69605108    13G    Page 3 of 8 Pages

     

      1    

      Names of Reporting Persons

     

      BCIP Life Sciences Associates, LP

      2  

      Check the Appropriate Box if a Member of a Group

     

      (a)  ☐        (b)  ☐

      3  

      SEC Use Only

     

      4  

      Citizenship or Place of Organization

     

      Delaware

    Number of

    Shares

    Beneficially 

    Owned by

    Each

    Reporting

    Person

    With

       5     

      Sole Voting Power

     

      0 Ordinary Shares

       6   

      Shared Voting Power

     

      201,347 Ordinary Shares

       7   

      Sole Dispositive Power

     

      0 Ordinary Shares

       8   

      Shared Dispositive Power

     

      201,347 Ordinary Shares

      9    

      Aggregate Amount Beneficially Owned by Each Reporting Person

     

      201,347 Ordinary Shares

    10  

      Check if the Aggregate Amount in Row (9) Excludes Certain Shares

     

      ☐

    11  

      Percent of Class Represented by Amount in Row 9

     

      0.4%

    12  

      Type of Reporting Person

     

      PN


    CUSIP No. N69605108    13G    Page 4 of 8 Pages

     

      1    

      Names of Reporting Persons

     

      Bain Capital Life Sciences Opportunities III, LP

      2  

      Check the Appropriate Box if a Member of a Group

     

      (a)  ☐        (b)  ☐

      3  

      SEC Use Only

     

      4  

      Citizenship or Place of Organization

     

      Delaware

    Number of

    Shares

    Beneficially 

    Owned by

    Each

    Reporting

    Person

    With

       5     

      Sole Voting Power

     

      0 Ordinary Shares

       6   

      Shared Voting Power

     

      1,182,217 Ordinary Shares

       7   

      Sole Dispositive Power

     

      0 Ordinary Shares

       8   

      Shared Dispositive Power

     

      1,182,217 Ordinary Shares

      9    

      Aggregate Amount Beneficially Owned by Each Reporting Person

     

      1,182,217 Ordinary Shares

    10  

      Check if the Aggregate Amount in Row (9) Excludes Certain Shares

     

      ☐

    11  

      Percent of Class Represented by Amount in Row 9

     

      2.3%

    12  

      Type of Reporting Person

     

      PN


    CUSIP No. N69605108    13G    Page 5 of 8 Pages

     

    Item 1(a)

    Name of Issuer

    The name of the issuer to which this filing on Schedule 13G relates is Pharvaris N.V. (the “Issuer”).

     

    Item 1(b)

    Address of Issuer’s Principal Executive Offices

    The principal executive office of the Issuer is located at Emmy Noetherweg 2, 2333 BK Leiden, The Netherlands.

     

    Item 2(a)

    Name of Person Filing

    This Schedule 13G is being filed jointly by Bain Capital Life Sciences Fund, L.P., a Cayman Islands exempted limited partnership (“BCLS Fund I”), BCIP Life Sciences Associates, LP, a Delaware limited partnership (“BCIPLS”), and Bain Capital Life Sciences Opportunities III, LP, a Delaware limited partnership (“BCLS Fund III Opportunities” and, together with BCLS Fund I and BCIPLS, the “Reporting Persons”).

    Bain Capital Life Sciences Investors, LLC, a Delaware limited liability company (“BCLSI”), is the general partner of Bain Capital Life Sciences Partners, LP, a Cayman Islands exempted limited partnership (“BCLSP”), which is the general partner of BCLS Fund I. BCLSI is also the manager of Bain Capital Life Sciences III General Partner, LLC, a Delaware limited liability company (“BCLS Fund III GP”), which is the general partner of Bain Capital Life Sciences Fund III, L.P., a Delaware limited partnership (“BCLS Fund III”), which is the sole member of Bain Capital Life Sciences Opportunities III GP, LLC, a Delaware limited liability company (“BCLS Fund III Opportunities GP”), which is the general partner of BCLS Fund III Opportunities.

    Boylston Coinvestors, LLC, a Delaware limited liability company (“Boylston” and, together with the Reporting Persons, BCLSI, BCLSP, BCLS Fund III GP, BCLS Fund III and BCLS Fund III Opportunities GP, the “Bain Capital Life Sciences Entities”), is the general partner of BCIPLS. BCLSI governs the investment strategy and decision-making process with respect to investments held by BCIPLS.

    As a result, BCLSI may be deemed to share voting and dispositive power with respect to the securities held by the Reporting Persons.

    The Reporting Persons have entered into a Joint Filing Agreement, dated January 22, 2024, pursuant to which the Reporting Persons have agreed to file this Schedule 13G jointly in accordance with the provisions of Rule 13d-1(k)(1) promulgated under the Act.

     

    Item 2(b)

    Address of Principal Business Office or, if None, Residence

    The principal business address for each of the Bain Capital Life Sciences Entities is 200 Clarendon Street, Boston, Massachusetts 02116.

     

    Item 2(c)

    Citizenship

    BCLS Fund I and BCLSP are each organized under the laws of the Cayman Islands. BCIPLS, BCLS Fund III Opportunities, BCLSI, BCLS Fund III GP, BCLS Fund III, BCLS Fund III Opportunities GP and Boylston are each organized under the laws of the State of Delaware.

     

    Item 2(d)

    Title of Class of Securities

    The class of securities of the Issuer to which this Schedule 13G relates is Ordinary Shares, €0.12 par value per share (the “Ordinary Shares”).

     

    Item 2(e)

    CUSIP Number

    The CUSIP number of the Ordinary Shares is N69605108.


    CUSIP No. N69605108    13G    Page 6 of 8 Pages

     

    Item 3

    If this statement is filed pursuant to §§ 240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a

     

    (a)    ☐    Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
    (b)    ☐    Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
    (c)    ☐    Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
    (d)    ☐    Investment company registered under Section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
    (e)    ☐    An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
    (f)    ☐    An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
    (g)    ☐    A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
    (h)    ☐    A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
    (i)    ☐    A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act (15 U.S.C. 80a-3);
    (j)    ☐    A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J);
    (k)    ☐    Group, in accordance with § 240.13d-1(b)(1)(ii)(K).

    If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:

     

    Item 4

    Ownership

    (a) Amount beneficially owned:

    As of the date hereof, (i) BCLS Fund I holds 1,967,093 Ordinary Shares, representing approximately 3.8% of the outstanding Ordinary Shares, (ii) BCIPLS holds 201,347 Ordinary Shares, representing approximately 0.4% of the outstanding Ordinary Shares, and (iii) BCLS Fund III Opportunities holds 1,182,217 Ordinary Shares, representing approximately 2.3% of the outstanding Ordinary Shares.

    As a result of the foregoing and the relationships described in Item 2(a), the Reporting Persons may be deemed to collectively beneficially own an aggregate of 3,350,657 Ordinary Shares, representing approximately 6.4% of the outstanding Ordinary Shares.

    The percentage of the outstanding Ordinary Shares held by the Reporting Persons is based on an aggregate of 52,108,675 Ordinary Shares issued and outstanding, as reported by the Issuer in its prospectus supplement filed with the Securities and Exchange Commission pursuant to Rule 424(b)(5) on December 7, 2023.

    (b) Percent of class:

    See Item 4(a) hereof.

    (c) Number of shares as to which the person has:

    (i) Sole power to vote or to direct the vote:

    0 Ordinary Shares


    CUSIP No. N69605108    13G    Page 7 of 8 Pages

     

    (ii) Shared power to vote or to direct the vote:

     

    BCLS Fund I    1,967,093 Ordinary Shares
    BCIPLS    201,347 Ordinary Shares
    BCLS Fund III Opportunities    1,182,217 Ordinary Shares
    (iii) Sole power to dispose or to direct the disposition of:
    0 Ordinary Shares   
    (iv) Shared power to dispose or to direct the disposition of:
    BCLS Fund I    1,967,093 Ordinary Shares
    BCIPLS    201,347 Ordinary Shares
    BCLS Fund III Opportunities    1,182,217 Ordinary Shares

     

    Item 5

    Ownership of Five Percent or Less of a Class

    Not applicable.

     

    Item 6

    Ownership of More Than Five Percent on Behalf of Another Person

    Not applicable.

     

    Item 7

    Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person

    Not applicable.

     

    Item 8

    Identification and Classification of Members of the Group

    Not applicable.

     

    Item 9

    Notice of Dissolution of Group

    Not applicable.

     

    Item 10

    Certifications

    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the Issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.


    CUSIP No. N69605108    13G    Page 8 of 8 Pages

     

    SIGNATURES

    After reasonable inquiry and to the best of its knowledge and belief, the undersigned certifies that the information in this statement is true, complete and correct.

     

    Dated: January 22, 2024     Bain Capital Life Sciences Fund, L.P.
        By:  

    Bain Capital Life Sciences Partners, LP,

    its general partner

        By:  

    Bain Capital Life Sciences Investors, LLC,

    its general partner

        By:   /s/ Ricky Sun
          Name:   Ricky Sun
          Title:   Partner
        BCIP Life Sciences Associates, LP
        By:  

    Boylston Coinvestors, LLC,

    its general partner

        By:   /s/ Ricky Sun
          Name:   Ricky Sun
          Title:   Authorized Signatory
        Bain Capital Life Sciences Opportunities III, LP
        By:  

    Bain Capital Life Sciences Opportunities III GP, LLC,

    its general partner

        By:  

    Bain Capital Life Sciences Fund III, L.P.,

    its sole member

        By:  

    Bain Capital Life Sciences III General Partner, LLC,

    its general partner

        By:  

    Bain Capital Life Sciences Investors, LLC,

    its manager

        By:   /s/ Ricky Sun
          Name:   Ricky Sun
          Title:   Partner

     

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      Formal letters received from FDA relating to the previously announced hold on clinical studies of PHA121 in the U.S.Top-line data anticipated in 4Q22 for RAPIDe-1, a global Phase 2 study of PHVS416 for the acute treatment of HAE attacks ongoing outside the U.S.Executing from a strong financial position with cash and cash equivalents of €201 million as of June 30, 2022 ZUG, Switzerland, Sept. 12, 2022 (GLOBE NEWSWIRE) -- Pharvaris (NASDAQ:PHVS), a clinical-stage company developing novel, oral bradykinin-B2-receptor antagonists to treat and prevent hereditary angioedema (HAE) attacks, today reported financial results for the second quarter ended June 30, 2022, and provided a business update

      9/12/22 6:50:00 AM ET
      $PHVS
      Biotechnology: Pharmaceutical Preparations
      Health Care