• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
PublishDashboard
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlertsPublish with Us
    Company
    AboutQuantisnow PlusContactJobsAI employees
    Legal
    Terms of usePrivacy policyCookie policy

    SEC Form SC 13G/A filed by ProQR Therapeutics N.V. (Amendment)

    12/23/22 4:39:00 PM ET
    $PRQR
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $PRQR alert in real time by email
    SC 13G/A 1 d419860dsc13ga.htm SC 13G/A SC 13G/A

     

     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    Washington, D.C. 20549

     

     

    SCHEDULE 13G

    Under the Securities Exchange Act of 1934

    (Amendment No. 1 )*

     

     

    ProQR Therapeutics N.V.

    (Name of Issuer)

    Ordinary Shares, nominal value 0.04 EUR per share

    (Title of Class of Securities)

    N71542109

    (CUSIP Number)

    December 21, 2022

    (Date of Event Which Requires Filing of this Statement)

     

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

     

      ☐

    Rule 13d-1(b)

     

      ☒

    Rule 13d-1(c)

     

      ☐

    Rule 13d-1(d)

     

    *

    The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

    The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

     

     

     


    SCHEDULE 13G

    CUSIP No. N71542109

     

      (1)    

      NAMES OF REPORTING PERSONS

     

      Eli Lilly and Company

      35-0470950

      (2)  

      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (see instructions)

     

      (a)  ☐        (b)  ☐

      (3)  

      SEC USE ONLY

     

      (4)  

      CITIZENSHIP OR PLACE OF ORGANIZATION

     

      Indiana

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH:

       (5)    

      SOLE VOTING POWER

     

      13,371,562

       (6)  

      SHARED VOTING POWER

     

      N/A

       (7)  

      SOLE DISPOSITIVE POWER

     

      13,371,562

       (8)  

      SHARED DISPOSITIVE POWER

     

      N/A

      (9)    

      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

      13,371,562

    (10)  

      CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (see instructions)

     

    (11)  

      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

     

      16.6%

    (12)  

      TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)

     

      CO


    SCHEDULE 13G

     

    Item 1    (a)

    Name of issuer:

    ProQR Therapeutics N.V.

     

      (b)

    Address of issuer’s principal executive offices:

    Darwinweg 24

    Leiden P7 2333CR

     

    Item 2    (a)

    Name of person filing:

    This Statement is filed on behalf of Eli Lilly and Company, an Indiana corporation

     

      (b)

    Address or principal business office or, if none, residence:

    Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana 46285

     

      (c)

    Citizenship:

    Eli Lilly and Company is an Indiana corporation.

     

      (d)

    Title of class of securities:

    Ordinary Shares, nominal value 0.04 EUR per share

     

      (e)

    CUSIP No.:

    N71542109

     

    Item 3.

    If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

    Not Applicable

     

    Item 4.

    Ownership:

    Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1.

     

      (a)

    Amount beneficially owned:

    13,371,562

     

      (b)

    Percent of class:

    16.6%

    Based on the representation and warranty set forth in a Share Purchase Agreement dated December 21, 2022 between the Issuer and Reporting Person (“the SPA”), that 71,434,624 Ordinary Shares were issued and outstanding on December 21, 2022 and the 9,381,586 Ordinary Shares purchased by the Reporting Person pursuant to the SPA.

     

      (c)

    Number of shares as to which the person has:

     

      (i)

    Sole power to vote or to direct the vote

    13,371,562

     

      (ii)

    Shared power to vote or to direct the vote

    N/A

     

      (iii)

    Sole power to dispose or to direct the disposition of

    13,371,562

     

      (iv)

    Shared power to dispose or to direct the disposition of

    N/A


    Item 5.

    Ownership of 5 Percent or Less of a Class.

    Not Applicable

     

    Item 6.

    Ownership of More than 5 Percent on Behalf of Another Person.

    Not Applicable

     

    Item 7.

    Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.

    Not Applicable

     

    Item 8.

    Identification and Classification of Members of the Group.

    Not Applicable

     

    Item 9.

    Notice of Dissolution of Group.

    Not Applicable

     

    Item 10.

    Certifications

    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect other than activities solely in connection with a nomination under §240.14a-11.

    SIGNATURE

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

    Date: December 22, 2022

     

    ELI LILLY AND COMPANY
    By:   *
      Authorized Signatory

     

      /s/ Christopher Anderson
    *By:   Christopher Anderson
      Attorney–in-Fact

    This Schedule 13G was executed pursuant to a power of attorney previously filed with the Securities and Exchange Commission, and hereby incorporated by reference herein. The power of attorney for Eli Lilly and Company was filed as an attachment to a filing by Eli Lilly and Company on Schedule 13G for Forma Therapeutics Holdings, Inc. on February 10, 2022.

    Get the next $PRQR alert in real time by email

    Chat with this insight

    Save time and jump to the most important pieces.

    Recent Analyst Ratings for
    $PRQR

    DatePrice TargetRatingAnalyst
    4/29/2025$5.00Outperform
    Evercore ISI
    4/29/2025$8.00Overweight
    Cantor Fitzgerald
    3/10/2025$4.00Neutral → Buy
    Citigroup
    1/10/2025$15.00Outperform
    Oppenheimer
    10/29/2024$6.00 → $14.00Outperform → Strong Buy
    Raymond James
    11/8/2023$2.00Neutral → Buy
    Chardan Capital Markets
    3/30/2023$1.50 → $5.00Mkt Perform → Mkt Outperform
    JMP Securities
    12/22/2022$0.80 → $5.00Neutral → Overweight
    Cantor Fitzgerald
    More analyst ratings

    $PRQR
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    See more
    • Evercore ISI initiated coverage on ProQR Therapeutics with a new price target

      Evercore ISI initiated coverage of ProQR Therapeutics with a rating of Outperform and set a new price target of $5.00

      4/29/25 8:12:03 AM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Cantor Fitzgerald resumed coverage on ProQR Therapeutics with a new price target

      Cantor Fitzgerald resumed coverage of ProQR Therapeutics with a rating of Overweight and set a new price target of $8.00

      4/29/25 8:11:53 AM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • ProQR Therapeutics upgraded by Citigroup with a new price target

      Citigroup upgraded ProQR Therapeutics from Neutral to Buy and set a new price target of $4.00

      3/10/25 7:58:48 AM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $PRQR
    SEC Filings

    See more
    • SEC Form 6-K filed by ProQR Therapeutics N.V.

      6-K - ProQR Therapeutics N.V. (0001612940) (Filer)

      6/3/25 4:11:07 PM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Amendment: SEC Form SCHEDULE 13G/A filed by ProQR Therapeutics N.V.

      SCHEDULE 13G/A - ProQR Therapeutics N.V. (0001612940) (Subject)

      5/12/25 9:07:00 AM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 6-K filed by ProQR Therapeutics N.V.

      6-K - ProQR Therapeutics N.V. (0001612940) (Filer)

      5/8/25 7:00:17 AM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $PRQR
    Press Releases

    Fastest customizable press release news feed in the world

    See more
    • ProQR Announces Upcoming Scientific Presentations at ASGCT and TIDES Conferences

      LEIDEN, Netherlands & CAMBRIDGE, Mass., May 12, 2025 (GLOBE NEWSWIRE) -- ProQR Therapeutics NV (NASDAQ:PRQR) (ProQR), a company dedicated to changing lives through transformative RNA therapies based on its proprietary Axiomer™ RNA editing technology platform, today announced that it will present at two upcoming scientific conferences: the American Society of Gene & Cell Therapy (ASGCT) 28th Annual Meeting, taking place May 13-17, 2025, in New Orleans, Louisiana and the TIDES USA 2025: Oligonucleotide and Peptide Therapeutics Conference, being held May 19-22, 2025, in San Diego, California. "We are excited to share these presentations with the scientific community, demonstrating the breadt

      5/12/25 8:00:00 AM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • ProQR Announces First Quarter 2025 Operating and Financial Results

      Axiomer™ ADAR-mediated RNA editing pipeline advancing across liver and CNS programs, with CTA filing on track for Q2 2025 for lead program AX-0810 targeting NTCP for Cholestatic diseases Strengthened leadership with appointments of Chief Financial Officer and Chief Medical Officer€ 132.4 million cash and cash equivalents as of end Q1 providing runway into mid-2027, plus additional potential milestones from Lilly partnership LEIDEN, Netherlands & CAMBRIDGE, Mass., May 08, 2025 (GLOBE NEWSWIRE) -- ProQR Therapeutics N.V. (NASDAQ:PRQR) (ProQR), a company dedicated to changing lives through transformative RNA therapies based on its proprietary Axiomer RNA editing technology platform, today r

      5/8/25 7:00:00 AM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • ProQR Announces Webcast of Presentation at the 2025 Citizens Life Sciences Conference

      LEIDEN, Netherlands & CAMBRIDGE, Mass., May 02, 2025 (GLOBE NEWSWIRE) -- ProQR Therapeutics NV. (NASDAQ:PRQR) (ProQR), a company dedicated to changing lives through transformative RNA therapies based on its proprietary Axiomer™ RNA editing technology platform today announced that Company management is scheduled to present at the Citizens (JMP) Life Sciences Conference in New York City on Thursday, May 8 at 11:30 AM EDT. A live webcast of the Company's fireside chat will be available from the "Investors & Media" section of ProQR's website under "Events". A replay of the webcast will then be available for approximately 30 days. About Axiomer™ ProQR is pioneering a next-generation RNA base

      5/2/25 8:00:00 AM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $PRQR
    Financials

    Live finance-specific insights

    See more

    $PRQR
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    See more

    $PRQR
    Leadership Updates

    Live Leadership Updates

    See more
    • ProQR Therapeutics to Host Virtual Analyst and Investor Event on December 11, 2024

      LEIDEN, Netherlands & CAMBRIDGE, Mass., Dec. 05, 2024 (GLOBE NEWSWIRE) -- ProQR Therapeutics N.V. (NASDAQ:PRQR) (ProQR), a company dedicated to changing lives through transformative RNA therapies, today announced that the Company will host a virtual Analyst and Investor Event on Wednesday, December 11, 2024 from 10:00 am until approximately 12:30 pm EST, including an Analyst Q&A session with members of the ProQR Management Team.  During the event, ProQR will highlight its proprietary Axiomer™ ADAR-mediated RNA editing platform, along with updates on its pipeline of development candidates including data updates and next steps on its programs for NTCP and B4GALT1, AX-0810 and AX-1412. Prese

      12/5/24 8:00:00 AM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • ProQR Announces Preclinical Proof of Concept Data for AX-0810 Axiomer™ RNA Editing Program Targeting NTCP for Cholestatic Diseases

      ProQR scientists report for the first time in the ADAR RNA editing field in vivo proof of target engagement (RNA editing) leading to meaningful changes in biomarkers in NHPs using Axiomer™ RNA Editing OligonucleotidesPreclinical proof of concept for the Company's AX-0810 program targeting NTCP for cholestatic diseases presented at ASGCT Annual MeetingManagement webinar May 9, 2024 at 8:00 am EDT LEIDEN, Netherlands & CAMBRIDGE, Mass., May 08, 2024 (GLOBE NEWSWIRE) -- ProQR Therapeutics NV (NASDAQ:PRQR) (ProQR), a company dedicated to changing lives through transformative RNA therapies, today announced new preclinical data for its proprietary Axiomer™ RNA editing technology platform, incl

      5/8/24 8:00:00 AM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • ProQR Announces Conference Call to Discuss Axiomer® RNA Editing Platform

      LEIDEN, Netherlands & CAMBRIDGE, Mass., Dec. 22, 2022 (GLOBE NEWSWIRE) -- ProQR Therapeutics N.V. (NASDAQ:PRQR) (ProQR), a company dedicated to changing lives through transformative RNA therapies, today announced that ProQR management will host an investor conference call and webcast to discuss the Company's Axiomer RNA editing technology platform following the recently announced partnership expansion with Lilly. ProQR will host the call on December 22, 2022, at 8:15am EST.  The live and archived webcast of the presentation will be accessible through this webcast link, or to access the live call by phone please register here. A dial-in and unique PIN will be provided to join the call. The

      12/22/22 6:15:00 AM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G/A filed by ProQR Therapeutics N.V. (Amendment)

      SC 13G/A - ProQR Therapeutics N.V. (0001612940) (Subject)

      2/14/24 6:08:12 AM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G/A filed by ProQR Therapeutics N.V. (Amendment)

      SC 13G/A - ProQR Therapeutics N.V. (0001612940) (Subject)

      2/9/24 6:37:13 AM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G filed by ProQR Therapeutics N.V.

      SC 13G - ProQR Therapeutics N.V. (0001612940) (Subject)

      9/14/23 5:20:05 PM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • ProQR Strengthens Leadership with Appointments of CFO and CMO to Support Next Phase of Growth

      LEIDEN, Netherlands & CAMBRIDGE, Mass., April 14, 2025 (GLOBE NEWSWIRE) -- ProQR Therapeutics NV. (NASDAQ:PRQR) (ProQR), a company dedicated to changing lives through transformative RNA therapies based on its proprietary Axiomer™ RNA editing technology platform, today announced the appointment of Dennis Hom as Chief Financial Officer (CFO) and Cristina Lopez Lopez, MD, PhD, as Chief Medical Officer (CMO). These key leadership appointments support the advancement of the Company's Axiomer platform technology and pipeline of RNA editing programs as it enters the clinical stage. "We are thrilled to welcome Dennis and Cristina to ProQR at such an important time in our evolution," said Daniel A

      4/14/25 7:00:00 AM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • ProQR Appoints Peter A. Beal, PhD, as Chief ADAR Scientist

      LEIDEN, Netherlands & CAMBRIDGE, Mass., Dec. 10, 2024 (GLOBE NEWSWIRE) -- ProQR Therapeutics NV. (NASDAQ:PRQR) (ProQR), a company dedicated to changing lives through transformative RNA therapies based on its proprietary Axiomer™ RNA editing technology platform, today announced the appointment of Dr. Peter Beal, a professor of Chemistry at the University of California, Davis, as Chief ADAR Scientist. Dr. Beal, one of the top experts in ADAR and RNA biology and chemistry, has been a long-term collaborator of ProQR and a valued member of ProQR's Scientific Advisory Board, where he has played an important role in shaping the Company's ADAR-based RNA editing platform. Dr. Beal's decades of res

      12/10/24 8:00:00 AM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • ProQR Appoints John Maraganore, PhD, as Strategic Advisor to the Supervisory Board

      LEIDEN, Netherlands & CAMBRIDGE, Mass., March 07, 2022 (GLOBE NEWSWIRE) -- ProQR Therapeutics N.V. (NASDAQ:PRQR) (the "Company"), a company dedicated to changing lives through the creation of transformative RNA therapies for genetic eye diseases, today announced that John Maraganore, PhD, biopharma industry leader and the former founding CEO of Alnylam Pharmaceuticals, has joined ProQR as a strategic advisor.  "It is a great honor to have John engaged with ProQR as a strategic advisor to the Supervisory Board to support us in defining the next steps for the Company, while we continue to analyze data from the Illuminate trial of sepofarsen and identify next steps for the program, if any,"

      3/7/22 7:00:00 AM ET
      $PRQR
      Biotechnology: Pharmaceutical Preparations
      Health Care