SEC Form SC 13G/A filed by Talis Biomedical Corporation (Amendment)
| UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 | 
| Talis Biomedical Corporation | 
| Common Stock, par value $0.0001 per share | 
| 87424L108 | 
| December 31, 2022 | 
| (Date of Event which Requires Filing of this Statement) | 
| 1 | Names of Reporting Persons. Greenlight Capital, Inc. | 
| 2 | Check the Appropriate Box if a Member of a Group (See Instructions) | 
| (a)            [ ] | |
| (b)            [ ] | |
| 3 | SEC Use Only | 
| 4 | Citizenship or Place of Organization. Delaware | 
| Number of Shares Beneficially Owned by Each Reporting Person With | 5  Sole Voting Power 0 shares | ||
| 6  Shared Voting Power 1,051,739 shares | |||
| 7  Sole Dispositive Power 0 shares | |||
| 8  Shared Dispositive Power 1,051,739 shares | 
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person 1,051,739 shares | |
| 10 | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)     [ ] | |
| 11 | Percent of Class Represented by Amount in Row (9) 3.9% | |
| 12 | Type of Reporting Person (See Instructions) IA | 
| 1 | Names of Reporting Persons. DME Capital Management, LP | 
| 2 | Check the Appropriate Box if a Member of a Group (See Instructions) | 
| (a)            [ ] | |
| (b)            [ ] | |
| 3 | SEC Use Only | 
| 4 | Citizenship or Place of Organization. Delaware | 
| Number of Shares Beneficially Owned by Each Reporting Person With | 5  Sole Voting Power 0 shares | ||
| 6  Shared Voting Power 892,504 shares | |||
| 7  Sole Dispositive Power 0 shares | |||
| 8  Shared Dispositive Power 892,504 shares | 
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person 892,504 shares | |
| 10 | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)     [ ] | |
| 11 | Percent of Class Represented by Amount in Row (9) 3.3% | |
| 12 | Type of Reporting Person (See Instructions) IA | 
| 1 | Names of Reporting Persons. DME Advisors, LP | 
| 2 | Check the Appropriate Box if a Member of a Group (See Instructions) | 
| (a)            [ ] | |
| (b)            [ ] | |
| 3 | SEC Use Only | 
| 4 | Citizenship or Place of Organization. Delaware | 
| Number of Shares Beneficially Owned by Each Reporting Person With | 5  Sole Voting Power 0 shares | ||
| 6  Shared Voting Power 291,540 shares | |||
| 7  Sole Dispositive Power 0 shares | |||
| 8  Shared Dispositive Power 291,540 shares | 
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person 291,540 shares | |
| 10 | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)     [ ] | |
| 11 | Percent of Class Represented by Amount in Row (9) 1.1% | |
| 12 | Type of Reporting Person (See Instructions) IA | 
| 1 | Names of Reporting Persons. DME Advisors GP, LLC | 
| 2 | Check the Appropriate Box if a Member of a Group (See Instructions) | 
| (a)            [ ] | |
| (b)            [ ] | |
| 3 | SEC Use Only | 
| 4 | Citizenship or Place of Organization. Delaware | 
| Number of Shares Beneficially Owned by Each Reporting Person With | 5  Sole Voting Power 0 shares | ||
| 6  Shared Voting Power 1,184,044 shares | |||
| 7  Sole Dispositive Power 0 shares | |||
| 8  Shared Dispositive Power 1,184,044 shares | 
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person 1,184,044 shares | |
| 10 | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)     [ ] | |
| 11 | Percent of Class Represented by Amount in Row (9) 4.4% | |
| 12 | Type of Reporting Person (See Instructions) HC | 
| 1 | Names of Reporting Persons. David Einhorn | 
| 2 | Check the Appropriate Box if a Member of a Group (See Instructions) | 
| (a)            [ ] | |
| (b)            [ ] | |
| 3 | SEC Use Only | 
| 4 | Citizenship or Place of Organization. U.S. Citizen | 
| Number of Shares Beneficially Owned by Each Reporting Person With | 5  Sole Voting Power 0 shares | ||
| 6  Shared Voting Power 2,235,783 shares | |||
| 7  Sole Dispositive Power 0 shares | |||
| 8  Shared Dispositive Power 2,235,783 shares | 
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person 2,235,783 shares | |
| 10 | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)     [ ] | |
| 11 | Percent of Class Represented by Amount in Row (9) 8.3% | |
| 12 | Type of Reporting Person (See Instructions) HC | 
| Item 4. | Ownership | 
| Exhibits | Exhibit | 
| 99.1 | Joint Filing Agreement by and among the Reporting Persons, incorporated by reference to Exhibit 99.1 to the Schedule 13G filed by the Reporting Persons with respect to the
              Company on February 14, 2022. | 
| GREENLIGHT CAPITAL, INC. | |
| By: /s/ DANIEL ROITMAN | |
| Daniel Roitman Chief Operating Officer | |
| DME CAPITAL MANAGEMENT, LP | |
| By: DME Advisors GP, LLC, | |
| its General Partner | |
| By: /s/ DANIEL ROITMAN | |
| Daniel Roitman Chief Operating Officer | |
| DME ADVISORS, LP | |
| By: DME Advisors GP, LLC, | |
| its General Partner | |
| By: /s/ DANIEL ROITMAN | |
| Daniel Roitman Chief Operating Officer | |
| DME ADVISORS GP, LLC | |
| By: /s/ DANIEL ROITMAN | |
| Daniel Roitman Chief Operating Officer | |
| /s/ DANIEL ROITMAN* | |
| Daniel Roitman, on behalf of David Einhorn |