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    SEC Form SC 13G/A filed by Verve Therapeutics Inc. (Amendment)

    12/11/23 4:16:31 PM ET
    $VERV
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $VERV alert in real time by email
    SC 13G/A 1 tm2332458d1_sc13ga.htm SC 13G/A

     

     

     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    Washington, D.C. 20549

     

     

     

    Schedule 13G

     

    Under the Securities Exchange Act of 1934
    (Amendment No. 2)*

     

     

     

    Verve Therapeutics, Inc.

    (Name of Issuer)

     

    Common Stock, par value $0.001 per share

    (Title of Class of Securities)

     

    92539P101

    (CUSIP Number)

     

    December 1, 2023

    (Date of Event Which Requires Filing of this Statement)

     

     

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

     

    ¨Rule 13d-1(b)

     

    xRule 13d-1(c)

     

    ¨Rule 13d-1(d)

     

    *The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

     

    The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

     

     

     

     

    CUSIP No. 92539P101Page 2 of 24

     

    1

    NAME OF REPORTING PERSONS

     

    GV 2017, L.P.

    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ¨         (b) ¨

     

    3 SEC USE ONLY
    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON

    WITH:

    5

    SOLE VOTING POWER

     

    0

    6

    SHARED VOTING POWER

     

    6,108,442 (1)

    7

    SOLE DISPOSITIVE POWER

     

    0

    8

    SHARED DISPOSITIVE POWER

     

    6,108,442 (1)

    9

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    6,108,442 (1)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

     

    ¨

    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    7.6% (2)

    12

    TYPE OF REPORTING PERSON

     

    PN

           

    (1)Consists of 6,108,442 shares of Common Stock of Verve Therapeutics, Inc. (the “Issuer”) held directly by GV 2017, L.P. (the “2017 Partnership”). The general partner of the 2017 Partnership is GV 2017 GP, L.P. (“2017 GP”). The general partner of 2017 GP is GV 2017 GP, L.L.C. (“2017 LLC”). The sole member of 2017 LLC is Alphabet Holdings LLC (“Alphabet Holdings”). The sole member of Alphabet Holdings is XXVI Holdings Inc. (“XXVI”). The controlling stockholder of XXVI is Alphabet Inc. (Alphabet Inc., together with 2017 GP, 2017 LLC, Alphabet Holdings, and XXVI may be collectively referred to as the “2017 Partnership Affiliates”). Each of the 2017 Partnership Affiliates may be deemed to indirectly beneficially own (as that term is defined in Rule 13d-3 of the Securities Exchange Act of 1934 (as amended, the “Exchange Act”)) the securities directly beneficially owned by the 2017 Partnership.

     

    (2)Calculated in accordance with Rule 13(d)-3(d)(1)(i) promulgated under the Exchange Act and based on an aggregate total of 80,408,406 shares of the Issuer’s Common Stock outstanding as of December 1, 2023, as disclosed in the Issuer’s prospectus supplement filed with the U.S. Securities and Exchange Commission (the “SEC”) on November 29, 2023 (the “Prospectus Supplement”) (File No.: 333-267578).

     

     

    CUSIP No. 92539P101Page 3 of 24

     

    1

    NAME OF REPORTING PERSONS

     

    GV 2017 GP, L.P.

    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ¨         (b) ¨

     

    3 SEC USE ONLY
    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON

    WITH:

    5

    SOLE VOTING POWER

     

    0

    6

    SHARED VOTING POWER

     

    6,108,442 (1)

    7

    SOLE DISPOSITIVE POWER.

     

    0

    8

    SHARED DISPOSITIVE POWER

     

    6,108,442 (1)

    9

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    6,108,442 (1)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

     

    ¨

    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    7.6% (2)

    12

    TYPE OF REPORTING PERSON

     

    PN

           

    (1)Consists of 6,108,442 shares of Common Stock of the Issuer held directly by the 2017 Partnership. The general partner of the 2017 Partnership is 2017 GP. The general partner of 2017 GP is 2017 LLC. The sole member of 2017 LLC is Alphabet Holdings. The sole member of Alphabet Holdings is XXVI. The controlling stockholder of XXVI is Alphabet Inc. Each of the 2017 Partnership Affiliates may be deemed to indirectly beneficially own (as that term is defined in Rule 13d-3 of the Exchange Act) the securities directly beneficially owned by the 2017 Partnership.

     

    (2)Calculated in accordance with Rule 13(d)-3(d)(1)(i) promulgated under the Exchange Act and based on an aggregate total of 80,408,406 shares of the Issuer’s Common Stock outstanding as of December 1, 2023, as disclosed in the Prospectus Supplement.

     

     

    CUSIP No. 92539P101Page 4 of 24

     

    1

    NAME OF REPORTING PERSONS

     

    GV 2017 GP, L.L.C.

    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ¨         (b) ¨

     

    3 SEC USE ONLY
    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON

    WITH:

    5

    SOLE VOTING POWER

     

    0

    6

    SHARED VOTING POWER

     

    6,108,442 (1)

    7

    SOLE DISPOSITIVE POWER.

     

    0

    8

    SHARED DISPOSITIVE POWER

     

    6,108,442 (1)

    9

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    6,108,442 (1)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

     

    ¨

    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    7.6% (2)

    12

    TYPE OF REPORTING PERSON

     

    OO

           

    (1)Consists of 6,108,442 shares of Common Stock of the Issuer held directly by the 2017 Partnership. The general partner of the 2017 Partnership is 2017 GP. The general partner of 2017 GP is 2017 LLC. The sole member of 2017 LLC is Alphabet Holdings. The sole member of Alphabet Holdings is XXVI. The controlling stockholder of XXVI is Alphabet Inc. Each of the 2017 Partnership Affiliates may be deemed to indirectly beneficially own (as that term is defined in Rule 13d-3 of the Exchange Act) the securities directly beneficially owned by the 2017 Partnership.

     

    (2)Calculated in accordance with Rule 13(d)-3(d)(1)(i) promulgated under the Exchange Act and based on an aggregate total of 80,408,406 shares of the Issuer’s Common Stock outstanding as of December 1, 2023, as disclosed in the Prospectus Supplement.

     

     

    CUSIP No. 92539P101Page 5 of 24

     

    1

    NAME OF REPORTING PERSONS

     

    GV 2019, L.P.

    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ¨      (b) ¨

     

    3 SEC USE ONLY
    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON

    WITH:

    5

    SOLE VOTING POWER

     

    0

    6

    SHARED VOTING POWER

     

    4,260,047 (1)

    7

    SOLE DISPOSITIVE POWER

     

    0

    8

    SHARED DISPOSITIVE POWER

     

    4,260,047 (1)

    9

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    4,260,047 (1)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

     

    ¨

    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    5.3% (2)

    12

    TYPE OF REPORTING PERSON

     

    PN

           

    (1)Consists of 4,260,047 shares of the Issuer’s Common Stock directly beneficially owned by GV 2019, L.P. (the “2019 Partnership”). The general partner of the 2019 Partnership is GV 2019 GP, L.P. (“2019 GP”). The general partner of 2019 GP is GV 2019 GP, L.L.C. (“2019 LLC”). The sole member of 2019 LLC is Alphabet Holdings. The sole member of Alphabet Holdings is XXVI. The controlling stockholder of XXVI is Alphabet Inc. (Alphabet Inc., together with 2019 GP, 2019 LLC, Alphabet Holdings, and XXVI may be referred to as the “2019 Partnership Affiliates”). Each of the 2019 Partnership Affiliates may be deemed to indirectly beneficially own (as that term is defined in Rule 13d-3 of the Exchange Act) the securities directly beneficially owned by the 2019 Partnership.

     

    (2)Calculated in accordance with Rule 13(d)-3(d)(1)(i) promulgated under the Exchange Act and based on an aggregate total of 80,408,406 shares of the Issuer’s Common Stock outstanding as of December 1, 2023, as disclosed in the Prospectus Supplement.

     

     

    CUSIP No. 92539P101Page 6 of 24

     

    1

    NAME OF REPORTING PERSONS

     

    GV 2019 GP, L.P.

    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ¨         (b) ¨

     

    3 SEC USE ONLY
    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON

    WITH:

    5

    SOLE VOTING POWER

     

    0

    6

    SHARED VOTING POWER

     

    4,260,047 (1)

    7

    SOLE DISPOSITIVE POWER.

     

    0

    8

    SHARED DISPOSITIVE POWER

     

    4,260,047 (1)

    9

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    4,260,047 (1)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

     

    ¨

    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    5.3% (2)

    12

    TYPE OF REPORTING PERSON

     

    PN

           

    (1)Consists of 4,260,047 shares of the Issuer’s Common Stock directly beneficially owned by the 2019 Partnership. The general partner of the 2019 Partnership is 2019 GP. The general partner of 2019 GP is 2019 LLC. The sole member of 2019 LLC is Alphabet Holdings. The sole member of Alphabet Holdings is XXVI. The controlling stockholder of XXVI is Alphabet Inc. Each of the 2019 Partnership Affiliates may be deemed to indirectly beneficially own (as that term is defined in Rule 13d-3 of the Exchange Act) the securities directly beneficially owned by the 2019 Partnership.

     

    (2)Calculated in accordance with Rule 13(d)-3(d)(1)(i) promulgated under the Exchange Act and based on an aggregate total of 80,408,406 shares of the Issuer’s Common Stock outstanding as of December 1, 2023, as disclosed in the Prospectus Supplement.

     

     

    CUSIP No. 92539P101Page 7 of 24

     

    1

    NAME OF REPORTING PERSONS

     

    GV 2019 GP, L.L.C.

    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ¨      (b) ¨

     

    3 SEC USE ONLY
    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON

    WITH:

    5

    SOLE VOTING POWER

     

    0

    6

    SHARED VOTING POWER

     

    4,260,047 (1)

    7

    SOLE DISPOSITIVE POWER.

     

    0

    8

    SHARED DISPOSITIVE POWER

     

    4,260,047 (1)

    9

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    4,260,047 (1)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

     

    ¨

    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    5.3% (2)

    12

    TYPE OF REPORTING PERSON

     

    OO

           

    (1)Consists of 4,260,047 shares of the Issuer’s Common Stock directly beneficially owned by the 2019 Partnership. The general partner of the 2019 Partnership is 2019 GP. The general partner of 2019 GP is 2019 LLC. The sole member of 2019 LLC is Alphabet Holdings. The sole member of Alphabet Holdings is XXVI. The controlling stockholder of XXVI is Alphabet Inc. Each of the 2019 Partnership Affiliates may be deemed to indirectly beneficially own (as that term is defined in Rule 13d-3 of the Exchange Act) the securities directly beneficially owned by the 2019 Partnership.

     

    (2)Calculated in accordance with Rule 13(d)-3(d)(1)(i) promulgated under the Exchange Act and based on an aggregate total of 80,408,406 shares of the Issuer’s Common Stock outstanding as of December 1, 2023, as disclosed in the Prospectus Supplement.

     

     

    CUSIP No. 92539P101Page 8 of 24

     

    1

    NAME OF REPORTING PERSONS

     

    GV 2023, L.P.

    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ¨      (b) ¨

     

    3 SEC USE ONLY
    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON

    WITH:

    5

    SOLE VOTING POWER

     

    0

    6

    SHARED VOTING POWER

     

    1,800,000 (1)

    7

    SOLE DISPOSITIVE POWER

     

    0

    8

    SHARED DISPOSITIVE POWER

     

    1,800,000 (1)

    9

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    1,800,000 (1)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

     

    ¨

    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    2.2% (2)

    12

    TYPE OF REPORTING PERSON

     

    PN

           

    (1)Consists of 1,800,000 shares of the Issuer’s Common Stock directly beneficially owned by GV 2023, L.P. (the “2023 Partnership”). The general partner of the 2023 Partnership is GV 2023 GP, L.P. (“2023 GP”). The general partner of 2023 GP is GV 2023 GP, L.L.C. (“2023 LLC”). The sole member of 2023 LLC is Alphabet Holdings. The sole member of Alphabet Holdings is XXVI. The controlling stockholder of XXVI is Alphabet Inc. (Alphabet Inc., together with 2023 GP, 2023 LLC, Alphabet Holdings, and XXVI may be referred to as the “2023 Partnership Affiliates”). Each of the 2023 Partnership Affiliates may be deemed to indirectly beneficially own (as that term is defined in Rule 13d-3 of the Exchange Act) the securities directly beneficially owned by the 2023 Partnership.

     

    (2)Calculated in accordance with Rule 13(d)-3(d)(1)(i) promulgated under the Exchange Act and based on an aggregate total of 80,408,406 shares of the Issuer’s Common Stock outstanding as of December 1, 2023, as disclosed in the Prospectus Supplement.

     

     

    CUSIP No. 92539P101Page 9 of 24

     

    1

    NAME OF REPORTING PERSONS

     

    GV 2023 GP, L.P.

    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ¨       (b) ¨

     

    3 SEC USE ONLY
    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON

    WITH:

    5

    SOLE VOTING POWER

     

    0

    6

    SHARED VOTING POWER

     

    1,800,000 (1)

    7

    SOLE DISPOSITIVE POWER.

     

    0

    8

    SHARED DISPOSITIVE POWER

     

    1,800,000 (1)

    9

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    1,800,000 (1)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

     

    ¨

    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    2.2% (2)

    12

    TYPE OF REPORTING PERSON

     

    PN

           

    (1)Consists of 1,800,000 shares of the Issuer’s Common Stock directly beneficially owned by the 2023 Partnership. The general partner of the 2023 Partnership is 2023 GP. The general partner of 2023 GP is 2023 LLC. The sole member of 2023 LLC is Alphabet Holdings. The sole member of Alphabet Holdings is XXVI. The controlling stockholder of XXVI is Alphabet Inc. Each of the 2023 Partnership Affiliates may be deemed to indirectly beneficially own (as that term is defined in Rule 13d-3 of the Exchange Act) the securities directly beneficially owned by the 2023 Partnership.

     

    (2)Calculated in accordance with Rule 13(d)-3(d)(1)(i) promulgated under the Exchange Act and based on an aggregate total of 80,408,406 shares of the Issuer’s Common Stock outstanding as of December 1, 2023, as disclosed in the Prospectus Supplement.

     

     

    CUSIP No. 92539P101Page 10 of 24

     

    1

    NAME OF REPORTING PERSONS

     

    GV 2023 GP, L.L.C.

    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ¨      (b) ¨

     

    3 SEC USE ONLY
    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON

    WITH:

    5

    SOLE VOTING POWER

     

    0

    6

    SHARED VOTING POWER

     

    1,800,000 (1)

    7

    SOLE DISPOSITIVE POWER.

     

    0

    8

    SHARED DISPOSITIVE POWER

     

    1,800,000 (1)

    9

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    1,800,000 (1)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

     

    ¨

    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    2.2% (2)

    12

    TYPE OF REPORTING PERSON

     

    OO

           

    (1)Consists of 1,800,000 shares of the Issuer’s Common Stock directly beneficially owned by the 2023 Partnership. The general partner of the 2023 Partnership is 2023 GP. The general partner of 2023 GP is 2023 LLC. The sole member of 2023 LLC is Alphabet Holdings. The sole member of Alphabet Holdings is XXVI. The controlling stockholder of XXVI is Alphabet Inc. Each of the 2023 Partnership Affiliates may be deemed to indirectly beneficially own (as that term is defined in Rule 13d-3 of the Exchange Act) the securities directly beneficially owned by the 2023 Partnership.

     

    (2)Calculated in accordance with Rule 13(d)-3(d)(1)(i) promulgated under the Exchange Act and based on an aggregate total of 80,408,406 shares of the Issuer’s Common Stock outstanding as of December 1, 2023, as disclosed in the Prospectus Supplement.

     

     

    CUSIP No. 92539P101Page 11 of 24

     

    1

    NAME OF REPORTING PERSONS

     

    Alphabet Holdings LLC

    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ¨        (b) ¨

     

    3 SEC USE ONLY
    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON

    WITH:

    5

    SOLE VOTING POWER

     

    0

    6

    SHARED VOTING POWER

     

    12,168,489 (1)

    7

    SOLE DISPOSITIVE POWER.

     

    0

    8

    SHARED DISPOSITIVE POWER

     

    12,168,489 (1)

    9

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    12,168,489 (1)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

     

    ¨

    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    15.1%(2)

    12

    TYPE OF REPORTING PERSON

     

    OO

           

    (1)Consists of the following shares of the Issuer’s Common Stock: (i) 6,108,442 shares directly beneficially owned by the 2017 Partnership; (ii) 4,260,047 shares directly beneficially owned by the 2019 Partnership; and (iii) 1,800,000 shares directly beneficially owned by the 2023 Partnership. As described more specifically in the footnotes to the tables set forth hereinabove, Alphabet Holdings may be deemed to have indirect beneficial ownership of the securities directly beneficially owned by the 2017 Partnership, the 2019 Partnership, and the 2023 Partnership.

     

    (2)Calculated in accordance with Rule 13(d)-3(d)(1)(i) promulgated under the Exchange Act and based on an aggregate total of 80,408,406 shares of the Issuer’s Common Stock outstanding as of December 1, 2023, as disclosed in the Prospectus Supplement.

     

     

    CUSIP No. 92539P101Page 12 of 24

     

    1

    NAME OF REPORTING PERSONS

     

    Verily Life Sciences LLC

    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ¨     (b) ¨

     

    3 SEC USE ONLY
    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON

    WITH:

    5

    SOLE VOTING POWER

     

    0

    6

    SHARED VOTING POWER

     

    180,597 (1)

    7

    SOLE DISPOSITIVE POWER.

     

    0

    8

    SHARED DISPOSITIVE POWER

     

    180,597 (1)

    9

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    180,597 (1)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

     

    ¨

    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    0.2% (2)

    12

    TYPE OF REPORTING PERSON

     

    OO

           

    (1)Consists of 180,597 shares of the Issuer’s Common Stock directly beneficially owned by Verily Life Sciences LLC (“Verily”). The controlling member of Verily is XXVI. The controlling stockholder of XXVI is Alphabet Inc. Each of XXVI and Alphabet Inc. may be deemed to indirectly beneficially own (as that term is defined in Rule 13d-3 of the Exchange Act) the securities directly beneficially owned by Verily.

     

    (2)Calculated in accordance with Rule 13(d)-3(d)(1)(i) promulgated under the Exchange Act and based on an aggregate total of 80,408,406 shares of the Issuer’s Common Stock outstanding as of December 1, 2023, as disclosed in the Prospectus Supplement.

     

     

    CUSIP No. 92539P101Page 13 of 24

     

    1

    NAME OF REPORTING PERSONS

     

    XXVI Holdings Inc.

    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ¨      (b) ¨

     

    3 SEC USE ONLY
    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON

    WITH:

    5

    SOLE VOTING POWER

     

    0

    6

    SHARED VOTING POWER

     

    12,349,086 (1)

    7

    SOLE DISPOSITIVE POWER.

     

    0

    8

    SHARED DISPOSITIVE POWER

     

    12,349,086 (1)

    9

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    12,349,086 (1)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

     

    ¨

    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    15.4%(2)

    12

    TYPE OF REPORTING PERSON

     

    CO

           

    (1)Consists of the following shares of the Issuer’s Common Stock (i) 6,108,442 shares directly beneficially owned by the 2017 Partnership; (ii) 4,260,047 shares directly beneficially owned by the 2019 Partnership; (iii) 1,800,000 shares directly beneficially owned by the 2023 Partnership; and (iv) 180,597 shares directly beneficially owned by Verily. As described more specifically in the footnotes to the tables set forth hereinabove, XXVI may be deemed to have indirect beneficial ownership of the securities directly beneficially owned by the 2017 Partnership, the 2019 Partnership, the 2023 Partnership, and Verily.

     

    (2)Calculated in accordance with Rule 13(d)-3(d)(1)(i) promulgated under the Exchange Act and based on an aggregate total of 80,408,406 shares of the Issuer’s Common Stock outstanding as of December 1, 2023, as disclosed in the Prospectus Supplement.

     

     

    CUSIP No. 92539P101Page 14 of 24

     

    1

    NAME OF REPORTING PERSONS

     

    Alphabet Inc.

    2

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ¨    (b) ¨

     

    3 SEC USE ONLY
    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON

    WITH:

    5

    SOLE VOTING POWER

     

    0

    6

    SHARED VOTING POWER

     

    12,349,086 (1)

    7

    SOLE DISPOSITIVE POWER.

     

    0

    8

    SHARED DISPOSITIVE POWER

     

    12,349,086 (1)

    9

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    12,349,086 (1)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

     

    ¨

    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    15.4%(2)

    12

    TYPE OF REPORTING PERSON

     

    CO, HC

           

    (1)Consists of the following shares of the Issuer’s Common Stock: (i) 6,108,442 shares directly beneficially owned by the 2017 Partnership; (ii) 4,260,047 shares directly beneficially owned by the 2019 Partnership; (iii) 1,800,000 shares directly beneficially owned by the 2023 Partnership; and (iv) 180,597 shares directly beneficially owned by Verily. As described more specifically in the footnotes to the tables set forth hereinabove, Alphabet Inc. may be deemed to have indirect beneficial ownership of the securities directly beneficially owned by the 2017 Partnership, the 2019 Partnership, the 2023 Partnership, and Verily.

     

    (2)Calculated in accordance with Rule 13(d)-3(d)(1)(i) promulgated under the Exchange Act and based on an aggregate total of 80,408,406 shares of the Issuer’s Common Stock outstanding as of December 1, 2023, as disclosed in the Prospectus Supplement.

     

     

    CUSIP No. 92539P101Page 15 of 24

     

    This Amendment No. 2 (this “Amendment”) amends the Statement (the “Statement”) on Schedule 13G initially filed by certain of the Reporting Persons (as defined in Item 2(a) below) on February 14, 2022 with the U.S. Securities and Exchange Commission (the “SEC”), as subsequently amended by Amendment No. 1, filed on February 10, 2023. This Amendment is being filed to report: (i) the admission of certain additional investors to the Reporting Persons’ 13(d) group and (ii) the Reporting Persons’ reliance, effective as of December 1, 2023 (the “Event Date”) on the exemption afforded by Rule 13d-1(c), promulgated under the Securities Exchange Act of 1934, as amended (the “Exchange Act”), in connection with the Reporting Persons’ acquisition of an additional 2% or more of the Issuer’s (as defined in Item 1(a) below) registered class of securities, in the aggregate, within the trailing 12 month period preceding the Event Date.

     

    Item 1(a).Name of Issuer.

     

    Verve Therapeutics, Inc. (the “Issuer”)

     

    Item 1(b).Address of Issuer’s Principal Executive Offices.

     

    201 Brookline Avenue, Suite 601

    Boston, MA 02215

     

    Item 2(a).Name of Persons Filing.

     

    GV 2017, L.P., a Delaware limited partnership (the “2017 Partnership”)

    GV 2017 GP, L.P., a Delaware limited partnership (“2017 GP”)

    GV 2017 GP, L.L.C., a Delaware limited liability company (“2017 LLC”)

    GV 2019, L.P., a Delaware limited partnership (the “2019 Partnership”)

    GV 2019 GP, L.P., a Delaware limited partnership (“2019 GP”)

    GV 2019 GP, L.L.C., a Delaware limited liability company (“2019 LLC”)

    GV 2023, L.P., a Delaware limited partnership (the “2023 Partnership”)

    GV 2023 GP, L.P., a Delaware limited partnership (“2023 GP”)

    GV 2023 GP, L.L.C., a Delaware limited liability company (“2023 LLC”)

    Alphabet Holdings LLC, a Delaware limited liability company (“Alphabet Holdings”)

    Verily Life Sciences LLC, a Delaware limited liability company (“Verily”)

    XXVI Holdings Inc., a Delaware corporation (“XXVI”), and

    Alphabet Inc., a Delaware corporation (“Parent” and, together with the 2017 Partnership, 2017 GP, 2017 LLC, the 2019 Partnership, 2019 GP, 2019 LLC, the 2023 Partnership, 2023 GP, 2023 LLC, Alphabet Holdings, Verily, and XXVI, the “Reporting Persons”).

     

    Item 2(b).Address of Principal Business Office or, if none, Residence.

     

    The address of the principal business office of each of the Reporting Persons is:

     

    1600 Amphitheatre Parkway
    Mountain View, CA 94043

     

     

    CUSIP No. 92539P101Page 16 of 24

     

    Item 2(c).Citizenship.

     

    Each of the Reporting Persons is formed, organized or incorporated, as applicable, in the State of Delaware.

     

    Item 2(d).Title of Class of Securities.

     

    Common Stock, par value $0.001 per share

     

    Item 2(e).CUSIP Number.

     

    92539P101

     

    Item 3.If this statement is filed pursuant to §§240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a:

     

      (a) o Broker or dealer registered under Section 15 of the Act (15 U.S.C. 78o);
      (b) o Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
      (c) o Insurance company as defined in section 3(a)19) of the Act (15 U.S.C. 78c);
      (d) o Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
      (e) o An investment adviser in accordance with §240.13d-1(b)(1)(ii)(E);
      (f) o An employee benefit plan or endowment fund in accordance with §240.13d-1(b)(1)(ii)(F);
      (g) o A parent holding company or control person in accordance with §240.13d-1(b)(1)(ii)(G);
      (h) o A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
      (i) o A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
      (j) o A non-U.S. institution in accordance with §240.13d–1(b)(1)(ii)(J);
      (k) o Group, in accordance with §240.13d–1(b)(1)(ii)(K).
        If filing as a non-U.S. institution in accordance with §240.13d–1(b)(1)(ii)(J), please specify the type of institution:________________________________.

     

    Item 4.Ownership.

     

    Provide the following information regarding the aggregate number and percentage of the class of securities of the Issuer identified in Item 1.

     

    (a)Amount Beneficially Owned:

     

    Reference to “beneficial ownership” of securities for purposes of this Amendment shall be understood to refer to beneficial ownership as that term is defined in Rule 13d-3 of the Exchange Act.

     

     

    CUSIP No. 92539P101Page 17 of 24

     

    As of the Event Date, which is the date as of which the Reporting Persons became obligated to file this Amendment, the Reporting Persons may be deemed to beneficially own an aggregate 12,349,086 shares of the Issuer’s Common Stock.

     

    As of the Event Date, the 2017 Partnership was the direct beneficial owner of 6,108,442 of the shares of the Issuer’s Common Stock described in the preceding paragraph. 2017 GP is the general partner of the 2017 Partnership, and 2017 LLC is the general partner of 2017 GP. As such, 2017 GP and 2017 LLC may each be deemed to indirectly beneficially own the securities that are directly beneficially owned by the 2017 Partnership.

     

    As of the Event Date, the 2019 Partnership was the direct beneficial owner of 4,260,047 shares of the Issuer’s Common Stock described in the second paragraph of this Item 4(a). 2019 GP is the general partner of the 2019 Partnership, and 2019 LLC is the general partner of 2019 GP. As such, 2019 GP and 2019 LLC may each be deemed to indirectly beneficially own the securities that are directly beneficially owned by the 2019 Partnership.

     

    As of Event Date, the 2023 Partnership was the direct beneficial owner of 1,800,000 shares of the Issuer’s Common Stock described in the second paragraph of this Item 4(a). 2023 GP is the general partner of the 2023 Partnership, and 2023 LLC is the general partner of 2023 GP. As such, 2023 GP and 2023 LLC may each be deemed to indirectly beneficially own the securities that are directly beneficially owned by the 2023 Partnership.

     

    As of the Event Date, Alphabet Holdings was the sole managing member of 2017 LLC, 2019 LLC, and 2023 LLC. As such, Alphabet Holdings may be deemed to indirectly beneficially own all of the shares of the Issuer’s Common Stock which are directly beneficially owned by the 2017 Partnership, the 2019 Partnership, and the 2023 Partnership. Accordingly, Alphabet Holdings’ indirect beneficial ownership represents 12,168,489 shares, in the aggregate, of the shares described in the second paragraph of this Item 4(a).

     

    As of the Event Date, Verily was the direct beneficial owner of 180,597 shares of the Issuer’s Common Stock described in the second paragraph of this Item 4(a).

     

    Additionally, as of the Event Date: (i) XXVI was the controlling member of Verily and the sole member Alphabet Holdings; and (ii) Parent was the controlling stockholder of XXVI. As such, for purposes of Section 13(d) of the Exchange Act, each of XXVI and Parent may be deemed to indirectly beneficially own all of the Issuer’s securities directly or indirectly beneficially owned by each of the other Reporting Persons, comprising an aggregate total of 12,349,086 shares of the Issuer’s Common Stock.

     

    Notwithstanding, neither the filing of the Statement nor this Amendment shall be construed as an admission that any of: (i) the 2017 Partnership, 2017 GP and 2017 LLC (collectively, the “2017 Affiliates”); (ii) the 2019 Partnership, 2019 GP and 2019 LLC (collectively, the “2019 Affiliates”); (iii) the 2023 Partnership, 2023 GP and 2023 LLC (collectively, the “2023 Affiliates”); or (iv) Verily (Verily, the 2017 Affiliates, the 2019 Affiliates, and the 2023 Affiliates, as context dictates, each being referred to herein as an “Affiliate Group”), is or has been, for purposes of Sections 13(d) or 13(g) of the Exchange Act, the direct or indirect beneficial owner of any of the Issuer’s securities reported herein as beneficially owned by any other Affiliate Group. Each Affiliate Group expressly disclaims beneficial ownership of the securities beneficially owned by the other Affiliate Groups.

     

    (b)Percent of Class:

     

    As of the Event Date, the Reporting Persons were deemed to directly or indirectly beneficially own an aggregate 15.4% of the Issuer’s outstanding Common Stock. Of that percentage, beneficial ownership was attributable as follows: (i) 7.6%, directly to the 2017 Partnership and indirectly to each of 2017 GP and 2017 LLC; (ii) 5.3%, directly to the 2019 Partnership and indirectly to each of 2019 GP and 2019 LLC; (iii) 2.2%, directly to the 2023 Partnership and indirectly to each of 2023 GP and 2023 LLC; (iv) 0.2% directly to Verily; (v) 15.1%%, indirectly to Alphabet Holdings; and (vi) 15.4%, indirectly to each of XXVI and Parent.

     

     

    CUSIP No. 92539P101Page 18 of 24

     

    The aforementioned percentages were calculated in accordance with Rule 13(d)-3(d)(1)(i) promulgated under the Exchange Act and based on an aggregate total of 80,408,406 shares of the Issuer’s Common Stock outstanding as of December 1, 2023, as disclosed in the Issuer’s prospectus supplement filed with the SEC on November 29, 2023 (the “Prospectus Supplement”) (File No.: 333-267578).

     

    (c)Number of shares as to which such person has:

     

    (i)Sole power to vote or to direct the vote:

     

    Reporting Person  Number of Shares 
    2017 Partnership   0 
    2017 GP   0 
    2017 LLC   0 
    2019 Partnership   0 
    2019 GP   0 
    2019 LLC   0 
    2023 Partnership   0 
    2023 GP   0 
    2023 LLC   0 
    Alphabet Holdings   0 
    Verily   0 
    XXVI   0 
    Parent   0 

     

    (ii)Shared power to vote or to direct the vote:

     

    Reporting Person  Number of Shares 
    2017 Partnership   6,108,442 
    2017 GP   6,108,442 
    2017 LLC   6,108,442 
    2019 Partnership   4,260,047 
    2019 GP   4,260,047 
    2019 LLC   4,260,047 
    2023 Partnership   1,800,000 
    2023 GP   1,800,000 
    2023 LLC   1,800,000 
    Alphabet Holdings   12,168,489 
    Verily   180,597 
    XXVI   12,349,086 
    Parent   12,349,086 

     

     

    CUSIP No. 92539P101Page 19 of 24

     

    (iii)Sole power to dispose or to direct the disposition of:

     

    Reporting Person  Number of Shares 
    2017 Partnership   0 
    2017 GP   0 
    2017 LLC   0 
    2019 Partnership   0 
    2019 GP   0 
    2019 LLC   0 
    2023 Partnership   0 
    2023 GP   0 
    2023 LLC   0 
    Alphabet Holdings   0 
    Verily   0 
    XXVI   0 
    Parent   0 

     

    (iv)Shared power to dispose or to direct the disposition of:

     

    Reporting Person  Number of Shares 
    2017 Partnership   6,108,442 
    2017 GP   6,108,442 
    2017 LLC   6,108,442 
    2019 Partnership   4,260,047 
    2019 GP   4,260,047 
    2019 LLC   4,260,047 
    2023 Partnership   1,800,000 
    2023 GP   1,800,000 
    2023 LLC   1,800,000 
    Alphabet Holdings   12,168,489 
    Verily   180,597 
    XXVI   12,349,086 
    Parent   12,349,086 

     

    Item 5.Ownership of Five Percent or Less of a Class.

     

    If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than 5 percent of the class of securities, check the following ¨

     

     

    CUSIP No. 92539P101Page 20 of 24

     

    Item 6.Ownership of More than Five Percent on Behalf of Another Person.

     

    Under certain circumstances described more specifically in the respective: (i) limited partnership agreements of the 2017 Partnership, the 2019 Partnership, the 2023 Partnership, 2017 GP, 2019 GP, and 2023 GP and (ii) limited liability company agreements of 2017 LLC, 2019 LLC, 2023 LLC, and Verily, the general and limited partners or members, as the case may be, of each of such Reporting Persons may be deemed to have the right to receive dividends from, or proceeds from the sale of, the Issuer’s securities directly or indirectly owned by each Reporting Person of which it is a general partner, limited partner, or member.

     

    Item 7.Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person.

     

    Item 7 is not applicable.

     

    Item 8.Identification and Classification of Members of the Group.

     

    Item 8 is not applicable.

     

    Item 9.Notice of Dissolution of a Group.

     

    Item 9 is not applicable.

     

    Item 10.Certification.

     

    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

     

     

    CUSIP No. 92539P101Page 21 of 24

     

    SIGNATURE

     

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     

    GV 2017, L.P.   GV 2019, L.P.
         
      By: GV 2017 GP, L.P., its General Partner     By: GV 2019 GP, L.P., its General Partner
      By: GV 2017 GP, L.L.C., its General Partner     By: GV 2019 GP, L.L.C., its General Partner
         
        By: /s/ Inga Goldbard       By: /s/ Inga Goldbard
        Name: Inga Goldbard       Name: Inga Goldbard
        Title: General Counsel       Title: General Counsel
        Dated: December 11, 2023       Dated: December 11, 2023
         
    GV 2017 GP, L.P.   GV 2019 GP, L.P.
         
      By: GV 2017 GP, L.L.C., its General Partner     By: GV 2019 GP, L.L.C., its General Partner
         
         
        By: /s/ Inga Goldbard       By: /s/ Inga Goldbard
        Name: Inga Goldbard       Name: Inga Goldbard
        Title: General Counsel       Title: General Counsel
        Dated: December 11, 2023       Dated: December 11, 2023
         
    GV 2017 GP, L.L.C.   GV 2019 GP, L.L.C.
         
        By: /s/ Inga Goldbard       By: /s/ Inga Goldbard
        Name: Inga Goldbard       Name: Inga Goldbard
        Title: General Counsel       Title: General Counsel
        Dated: December 11, 2023       Dated: December 11, 2023

     

     

    CUSIP No. 92539P101Page 22 of 24

     

    VERILY LIFE SCIENCES LLC   GV 2023, L.P.
         
          By: GV 2023 GP, L.P., its General Partner
          By: GV 2023 GP, L.L.C., its General Partner
    By: /s/ Duncan Welstead    
    Name: Duncan Welstead       By: /s/ Inga Goldbard
    Title: Finance Director       Name: Inga Goldbard
    Dated: December 11, 2023       Title: General Counsel
            Dated: December 11, 2023
         
    XXVI HOLDINGS INC.   GV 2023 GP, L.P.
         
          By: GV 2023 GP, L.L.C., its General Partner
         
    By: /s/ Kathryn W. Hall       By: /s/ Inga Goldbard
    Name: Kathryn W. Hall       Name: Inga Goldbard
    Title: Assistant Secretary       Title: General Counsel
    Dated: December 11, 2023       Dated: December 11, 2023
         
    ALPHABET HOLDINGS LLC   GV 2023 GP, L.L.C.
         
    By: /s/ Kathryn W. Hall       By: /s/ Inga Goldbard
    Name: Kathryn W. Hall       Name: Inga Goldbard
    Title: Secretary       Title: General Counsel
    Dated: December 11, 2023       Dated: December 11, 2023
         
    ALPHABET INC.    
         
    By: /s/ Kathryn W. Hall    
    Name: Kathryn W. Hall    
    Title: Secretary    
    Dated: December 11, 2023    

     

     

    CUSIP No. 92539P101Page 23 of 24

     

    Exhibit 99.1

     

    JOINT FILING AGREEMENT

     

    Each of the undersigned hereby acknowledges and agrees, in compliance with the provisions of Rule 13d-1(k)(1) promulgated under the Securities Exchange Act of 1934, as amended, that the Statement on Schedule 13G with respect to the Common Stock, par value $0.001 per share, of Verve Therapeutics, Inc., to which this Agreement is attached as an Exhibit, and any amendments thereto, will be filed with the Securities and Exchange Commission jointly on behalf of the undersigned. This Agreement may be executed, either manually or electronically, in one or more counterparts.

     

    GV 2017, L.P.   GV 2019, L.P.
         
      By: GV 2017 GP, L.P., its General Partner     By: GV 2019 GP, L.P., its General Partner
      By: GV 2017 GP, L.L.C., its General Partner     By: GV 2019 GP, L.L.C., its General Partner
         
        By: /s/ Inga Goldbard       By: /s/ Inga Goldbard
        Name: Inga Goldbard       Name: Inga Goldbard
        Title: General Counsel       Title: General Counsel
        Dated: December 11, 2023       Dated: December 11, 2023
         
    GV 2017 GP, L.P.   GV 2019 GP, L.P.
         
      By: GV 2017 GP, L.L.C., its General Partner     By: GV 2019 GP, L.L.C., its General Partner
         
         
        By: /s/ Inga Goldbard       By: /s/ Inga Goldbard
        Name: Inga Goldbard       Name: Inga Goldbard
        Title: General Counsel       Title: General Counsel
        Dated: December 11, 2023       Dated: December 11, 2023
         
    GV 2017 GP, L.L.C.   GV 2019 GP, L.L.C.
         
        By: /s/ Inga Goldbard       By: /s/ Inga Goldbard
        Name: Inga Goldbard       Name: Inga Goldbard
        Title: General Counsel       Title: General Counsel
        Dated: December 11, 2023       Dated: December 11, 2023

     

     

    CUSIP No. 92539P101Page 24 of 24

     

    VERILY LIFE SCIENCES LLC   GV 2023, L.P.
         
          By: GV 2023 GP, L.P., its General Partner
          By: GV 2023 GP, L.L.C., its General Partner
    By: /s/ Duncan Welstead    
    Name: Duncan Welstead       By: /s/ Inga Goldbard
    Title: Finance Director       Name: Inga Goldbard
    Dated: December 11, 2023       Title: General Counsel
            Dated: December 11, 2023
         
    XXVI HOLDINGS INC.   GV 2023 GP, L.P.
         
          By: GV 2023 GP, L.L.C., its General Partner
         
    By: /s/ Kathryn W. Hall       By: /s/ Inga Goldbard
    Name: Kathryn W. Hall       Name: Inga Goldbard
    Title: Assistant Secretary       Title: General Counsel
    Dated: December 11, 2023       Dated: December 11, 2023
         
    ALPHABET HOLDINGS LLC   GV 2023 GP, L.L.C.
         
    By: /s/ Kathryn W. Hall       By: /s/ Inga Goldbard
    Name: Kathryn W. Hall       Name: Inga Goldbard
    Title: Secretary       Title: General Counsel
    Dated: December 11, 2023       Dated: December 11, 2023
         
    ALPHABET INC.    
         
    By: /s/ Kathryn W. Hall    
    Name: Kathryn W. Hall    
    Title: Secretary    
    Dated: December 11, 2023    

     

     

     

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    • Verve Therapeutics Announces Pipeline Progress and Reports First Quarter 2025 Financial Results

      Reported positive initial data from the Heart-2 Phase 1b clinical trial of VERVE-102 demonstrating dose-dependent decreases in blood LDL-C and PCSK9 Mean reduction in LDL-C of 53%, with a maximum reduction of 69%, observed after a single infusion of VERVE-102 in the 0.6 mg/kg dose cohort in the Heart-2 clinical trial Pulse-1 Phase 1b clinical trial of VERVE-201 targeting ANGPTL3 continues to progress with a program update expected in the second half of 2025 Cash, cash equivalents, and marketable securities of approximately $500 million; cash runway into mid-2027 BOSTON , May 14, 2025 (GLOBE NEWSWIRE) -- Verve Therapeutics, a clinical-stage company developing a new class of genetic med

      5/14/25 7:00:00 AM ET
      $VERV
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $VERV
    Analyst Ratings

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    • Verve Therapeutics upgraded by Cantor Fitzgerald

      Cantor Fitzgerald upgraded Verve Therapeutics from Neutral to Overweight

      4/15/25 8:57:58 AM ET
      $VERV
      Biotechnology: Pharmaceutical Preparations
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    • H.C. Wainwright initiated coverage on Verve Therapeutics with a new price target

      H.C. Wainwright initiated coverage of Verve Therapeutics with a rating of Buy and set a new price target of $15.00

      4/8/24 8:03:41 AM ET
      $VERV
      Biotechnology: Pharmaceutical Preparations
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    • Canaccord Genuity initiated coverage on Verve Therapeutics with a new price target

      Canaccord Genuity initiated coverage of Verve Therapeutics with a rating of Buy and set a new price target of $29.00

      4/13/23 7:37:44 AM ET
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    Large Ownership Changes

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    • SEC Form SC 13G filed by Verve Therapeutics Inc.

      SC 13G - Verve Therapeutics, Inc. (0001840574) (Subject)

      11/18/24 5:23:52 PM ET
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    • Amendment: SEC Form SC 13G/A filed by Verve Therapeutics Inc.

      SC 13G/A - Verve Therapeutics, Inc. (0001840574) (Subject)

      11/12/24 5:52:40 PM ET
      $VERV
      Biotechnology: Pharmaceutical Preparations
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    • Amendment: SEC Form SC 13G/A filed by Verve Therapeutics Inc.

      SC 13G/A - Verve Therapeutics, Inc. (0001840574) (Subject)

      11/4/24 1:52:43 PM ET
      $VERV
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    $VERV
    Insider Purchases

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    • Ashe Andrew D. bought $475,760 worth of shares (76,000 units at $6.26), increasing direct ownership by 29% to 342,509 units (SEC Form 4)

      4 - Verve Therapeutics, Inc. (0001840574) (Issuer)

      5/15/24 5:30:07 PM ET
      $VERV
      Biotechnology: Pharmaceutical Preparations
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    • Yeshwant Krishna bought $18,000,000 worth of shares (1,800,000 units at $10.00) (SEC Form 4)

      4 - Verve Therapeutics, Inc. (0001840574) (Issuer)

      12/5/23 4:30:09 PM ET
      $VERV
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    Leadership Updates

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    • Climb Bio Appoints Seasoned Biotech Leaders to Board of Directors

      WELLESLEY HILLS, Mass., April 01, 2025 (GLOBE NEWSWIRE) -- Climb Bio, Inc. (NASDAQ:CLYM) today announced the appointments of biotech industry veterans Kim Cobleigh Drapkin, CPA, and Bo Cumbo to its Board of Directors. Ms. Drapkin will assume the role of Audit Committee Chair, and Mr. Cumbo will assume the role of Compensation Committee Chair. "We are delighted to welcome Kim and Bo to our Board of Directors at Climb Bio," said Aoife Brennan, President and CEO of Climb Bio. "Kim and Bo each bring three decades of leadership experience in the biotechnology and pharmaceutical industry, offering invaluable perspective as we continue to build the company and advance our pipeline. Their insight

      4/1/25 7:00:00 AM ET
      $ABOS
      $CLYM
      $LENZ
      $SLDB
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
      Biotechnology: Pharmaceutical Preparations
    • Verve Expands Leadership Team with Appointment of Frederick T. Fiedorek, M.D., as Chief Medical Officer

      BOSTON, Sept. 18, 2023 (GLOBE NEWSWIRE) -- Verve Therapeutics, a clinical-stage biotechnology company pioneering a new approach to the care of cardiovascular disease with single-course gene editing medicines, today announced the appointment of Frederick "Fred" T. Fiedorek, M.D., as chief medical officer (CMO). Andrew Bellinger, M.D., Ph.D., the current chief scientific officer (CSO) and CMO, will transition to the role of CSO. "We are excited by the continued expansion of the Verve team and the execution of a plan to become a multi-product clinical-stage company," said Sekar Kathiresan, M.D., co-founder and chief executive officer of Verve. "Our heart-1 clinical trial is well underway, wi

      9/18/23 6:30:00 AM ET
      $VERV
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Verve Therapeutics Appoints Experienced Biotechnology Executive, Alexander G. "Bo" Cumbo, to its Board of Directors

      CAMBRIDGE, Mass., June 13, 2022 (GLOBE NEWSWIRE) -- Verve Therapeutics, a biotechnology company pioneering a new approach to the care of cardiovascular disease with single-course gene editing medicines, today announced that Alexander G. "Bo" Cumbo, chief executive officer and president of AavantiBio, Inc., has joined the company's board of directors. "Bo is a highly experienced industry executive with a well-established track record of leading pharmaceutical and life sciences companies through critical processes in drug development and commercial execution," said Sekar Kathiresan, M.D., co-founder and chief executive officer of Verve. "As we focus on continued execution of our regulatory

      6/13/22 6:30:00 AM ET
      $VERV
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    $VERV
    Financials

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    • Verve Therapeutics Announces Positive Initial Data from the Heart-2 Phase 1b Clinical Trial of VERVE-102, an In Vivo Base Editing Medicine Targeting PCSK9

      Single infusion of VERVE-102 led to dose-dependent decreases in blood PCSK9 and LDL-C, with mean reduction in LDL-C of 53% and a maximum reduction of 69% observed in the 0.6 mg/kg dose cohort VERVE-102 was well-tolerated with no treatment-related serious adverse events and no clinically significant changes in ALT or platelets observed at any dose level among 14 participants VERVE-102 utilizes a proprietary GalNAc-LNP which has demonstrated a potentially best-in-class safety profile In the second half of 2025, Verve expects to report final Heart-2 dose escalation data, dose the first patient in a Phase 2 clinical trial for VERVE-102, and receive a decision from Eli Lilly and Company for th

      4/14/25 7:00:00 AM ET
      $VERV
      Biotechnology: Pharmaceutical Preparations
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    • Verve Therapeutics Announces Interim Data for VERVE-101 Demonstrating First Human Proof-of-Concept for In Vivo Base Editing with Dose-Dependent Reductions in LDL-C and Blood PCSK9 Protein in Patients with Heterozygous Familial Hypercholesterolemia

      LDL-C Reductions Up to 55% and Blood PCSK9 Protein Reductions Up to 84% Observed After a Single Infusion of VERVE-101 at Potentially Therapeutic Doses Safety Profile Supports Continued Development of VERVE-101 Enrollment Ongoing in the 0.45 mg/kg and 0.6 mg/kg Cohorts with Plans to Initiate Expansion Cohort in 2024 Company to Host Conference Call and Webcast Today at 6:30 p.m. ET BOSTON, Nov. 12, 2023 (GLOBE NEWSWIRE) -- Verve Therapeutics, Inc., a clinical-stage biotechnology company pioneering a new approach to the care of cardiovascular disease with single-course gene editing medicines, today announced first human proof-of-concept data for in vivo base editing from the ongoing hear

      11/12/23 3:30:00 PM ET
      $VERV
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    $VERV
    Insider Trading

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    • SEC Form 4 filed by Director Coats Lonnel

      4 - Verve Therapeutics, Inc. (0001840574) (Issuer)

      6/6/25 5:01:02 PM ET
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    • SEC Form 4 filed by Director Cumbo Alexander

      4 - Verve Therapeutics, Inc. (0001840574) (Issuer)

      6/6/25 5:01:06 PM ET
      $VERV
      Biotechnology: Pharmaceutical Preparations
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    • SEC Form 4 filed by Director Morrison Jodie Pope

      4 - Verve Therapeutics, Inc. (0001840574) (Issuer)

      6/6/25 5:00:55 PM ET
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    SEC Filings

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    • SEC Form EFFECT filed by Verve Therapeutics Inc.

      EFFECT - Verve Therapeutics, Inc. (0001840574) (Filer)

      5/15/25 12:15:05 AM ET
      $VERV
      Biotechnology: Pharmaceutical Preparations
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    • SEC Form 10-Q filed by Verve Therapeutics Inc.

      10-Q - Verve Therapeutics, Inc. (0001840574) (Filer)

      5/14/25 7:30:21 AM ET
      $VERV
      Biotechnology: Pharmaceutical Preparations
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    • Verve Therapeutics Inc. filed SEC Form 8-K: Results of Operations and Financial Condition, Financial Statements and Exhibits

      8-K - Verve Therapeutics, Inc. (0001840574) (Filer)

      5/14/25 7:15:09 AM ET
      $VERV
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