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    SEC Form SCHEDULE 13G filed by Eupraxia Pharmaceuticals Inc.

    11/13/25 12:14:47 PM ET
    $EPRX
    Pharmaceuticals and Biotechnology
    Health Care
    Get the next $EPRX alert in real time by email



    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549


    SCHEDULE 13G


    UNDER THE SECURITIES EXCHANGE ACT OF 1934
    EUPRAXIA PHARMACEUTICALS INC.

    (Name of Issuer)


    Common Shares

    (Title of Class of Securities)


    29842P105

    (CUSIP Number)


    12/31/2024

    (Date of Event Which Requires Filing of this Statement)


    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
    Checkbox not checked   Rule 13d-1(b)
    Checkbox not checked   Rule 13d-1(c)
    Checkbox checked   Rule 13d-1(d)






    SCHEDULE 13G

    CUSIP No.
    29842P105


    1Names of Reporting Persons

    MANCHESTER MANAGEMENT COMPANY, LLC
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    5,562,971.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    5,562,971.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    5,562,971.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    10.4 %
    12Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:  (1) The Reporting Person is reporting its beneficial ownership as of the date of filing. As of the trigger date, the Reporting Person was deemed to indirectly beneficially own, and share the power to vote or direct the disposition with respect to, an additional 20,000 Common Shares of the Issuer.


    SCHEDULE 13G

    CUSIP No.
    29842P105


    1Names of Reporting Persons

    MANCHESTER MANAGEMENT PR, LLC
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    PUERTO RICO
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    5,562,971.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    5,562,971.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    5,562,971.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    10.4 %
    12Type of Reporting Person (See Instructions)

    IA

    Comment for Type of Reporting Person:  (1) The Reporting Person is reporting its beneficial ownership as of the date of filing. As of the trigger date, the Reporting Person was deemed to indirectly beneficially own, and share the power to vote or direct the disposition with respect to, an additional 20,000 Common Shares of the Issuer.


    SCHEDULE 13G

    CUSIP No.
    29842P105


    1Names of Reporting Persons

    MANCHESTER EXPLORER, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    5,337,117.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    5,337,117.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    5,337,117.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    10.0 %
    12Type of Reporting Person (See Instructions)

    PN


    SCHEDULE 13G

    CUSIP No.
    29842P105


    1Names of Reporting Persons

    JAMES E. BESSER
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    UNITED STATES
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    276,586.00
    6Shared Voting Power

    5,562,971.00
    7Sole Dispositive Power

    276,586.00
    8Shared Dispositive Power

    5,562,971.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    5,839,557.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    10.9 %
    12Type of Reporting Person (See Instructions)

    IN

    Comment for Type of Reporting Person:  (1) The Reporting Person is reporting its beneficial ownership as of the date of filing. As of the trigger date, the Reporting Person was deemed to indirectly beneficially own, and share the power to vote or direct the disposition with respect to, an additional 20,000 Common Shares of the Issuer.


    SCHEDULE 13G

    CUSIP No.
    29842P105


    1Names of Reporting Persons

    MORGAN C. FRANK
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    UNITED STATES
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    307,306.00
    6Shared Voting Power

    5,337,117.00
    7Sole Dispositive Power

    307,306.00
    8Shared Dispositive Power

    5,337,117.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    5,644,423.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    10.6 %
    12Type of Reporting Person (See Instructions)

    IN


    SCHEDULE 13G

    Item 1. 
    (a)Name of issuer:

    EUPRAXIA PHARMACEUTICALS INC.
    (b)Address of issuer's principal executive offices:

    201-2067 CADBORO BAY RD., VICTORIA, BRITISH COLUMBIA, CANADA, V8R 5G4
    Item 2. 
    (a)Name of person filing:

    MANCHESTER MANAGEMENT COMPANY, LLC MANCHESTER MANAGEMENT PR, LLC MANCHESTER EXPLORER, L.P. JAMES E. BESSER MORGAN C. FRANK
    (b)Address or principal business office or, if none, residence:

    MANCHESTER MANAGEMENT COMPANY, LLC 2 CALLE CANDINA, #1701, SAN JUAN, PUERTO RICO, 00907 MANCHESTER MANAGEMENT PR, LLC 2 CALLE CANDINA, #1701, SAN JUAN, PUERTO RICO, 00907 MANCHESTER EXPLORER, L.P. 2 CALLE CANDINA, #1701, SAN JUAN, PUERTO RICO, 00907 JAMES E. BESSER 2 CALLE CANDINA, #1701, SAN JUAN, PUERTO RICO, 00907 MORGAN C. FRANK 2 CALLE CANDINA, #1701, SAN JUAN, PUERTO RICO, 00907
    (c)Citizenship:

    MANCHESTER MANAGEMENT COMPANY, LLC - Delaware MANCHESTER MANAGEMENT PR, LLC - Other - Puerto Rico MANCHESTER EXPLORER, L.P. - Delaware JAMES E. BESSER - United States MORGAN C. FRANK - United States
    (d)Title of class of securities:

    Common Shares
    (e)CUSIP No.:

    29842P105
    Item 3.If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
    (a)Checkbox not checked   Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
    (b)Checkbox not checked   Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
    (c)Checkbox not checked   Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
    (d)Checkbox not checked   Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
    (e)Checkbox not checked   An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
    (f)Checkbox not checked   An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
    (g)Checkbox not checked   A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
    (h)Checkbox not checked   A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
    (i)Checkbox not checked   A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
    (j)Checkbox not checked   A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
           please specify the type of institution:
    (k)Checkbox not checked   Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
     
    Item 4.Ownership
    (a)Amount beneficially owned:

    MANCHESTER MANAGEMENT COMPANY, LLC - 5,562,971 MANCHESTER MANAGEMENT PR, LLC - 5,562,971 MANCHESTER EXPLORER, L.P. - 5,337,117 JAMES E. BESSER - 5,839,557 MORGAN C. FRANK - 5,644,423
    (b)Percent of class:

    MANCHESTER MANAGEMENT COMPANY, LLC - 10.4% MANCHESTER MANAGEMENT PR, LLC - 10.4% MANCHESTER EXPLORER, L.P. - 10.0% JAMES E. BESSER - 10.9% MORGAN C. FRANK - 10.6%
    (c)Number of shares as to which the person has:
     (i) Sole power to vote or to direct the vote:

    MANCHESTER MANAGEMENT COMPANY, LLC - 0 MANCHESTER MANAGEMENT PR, LLC - 0 MANCHESTER EXPLORER, L.P. - 0 JAMES E. BESSER - 276,586 MORGAN C. FRANK - 307,306

     (ii) Shared power to vote or to direct the vote:

    MANCHESTER MANAGEMENT COMPANY, LLC - 5,562,971 MANCHESTER MANAGEMENT PR, LLC - 5,562,971 MANCHESTER EXPLORER, L.P. - 5,337,117 JAMES E. BESSER - 5,562,971 MORGAN C. FRANK - 5,337,117

     (iii) Sole power to dispose or to direct the disposition of:

    MANCHESTER MANAGEMENT COMPANY, LLC - 0 MANCHESTER MANAGEMENT PR, LLC - 0 MANCHESTER EXPLORER, L.P. - 0 JAMES E. BESSER - 276,586 MORGAN C. FRANK - 307,306

     (iv) Shared power to dispose or to direct the disposition of:

    MANCHESTER MANAGEMENT COMPANY, LLC - 5,562,971 MANCHESTER MANAGEMENT PR, LLC - 5,562,971 MANCHESTER EXPLORER, L.P. - 5,337,117 JAMES E. BESSER - 5,562,971 MORGAN C. FRANK - 5,337,117

    Item 5.Ownership of 5 Percent or Less of a Class.
     
    Item 6.Ownership of more than 5 Percent on Behalf of Another Person.
     
    If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required.


    All of the securities reported in this Schedule 13G, other than those securities reported herein that James E. Besser and Morgan C. Frank have the sole power to vote, direct the vote, dispose of or direct the disposition of, are directly owned by advisory clients of Manchester Management PR, LLC. None of those advisory clients, other than Manchester Explorer, L.P., may be deemed to beneficially own more than 5% of the Common Shares.
    Item 7.Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
     
    Not Applicable
    Item 8.Identification and Classification of Members of the Group.
     
    Not Applicable
    Item 9.Notice of Dissolution of Group.
     
    Not Applicable

    Item 10.Certifications:
     
    Not Applicable

        SIGNATURE 
     
    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     
    MANCHESTER MANAGEMENT COMPANY, LLC
     
    Signature:By: /s/ James E. Besser
    Name/Title:James E. Besser / Managing Member
    Date:11/13/2025
     
    MANCHESTER MANAGEMENT PR, LLC
     
    Signature:By: /s/ James E. Besser
    Name/Title:James E. Besser / Managing Member
    Date:11/13/2025
     
    MANCHESTER EXPLORER, L.P.
     
    Signature:By: /s/ James E. Besser
    Name/Title:James E. Besser / Managing Member of the General Partner
    Date:11/13/2025
     
    JAMES E. BESSER
     
    Signature:By: /s/ James E. Besser
    Name/Title:James E. Besser / Managing Member
    Date:11/13/2025
     
    MORGAN C. FRANK
     
    Signature:MORGAN C. FRANK
    Name/Title:By: /s/ Morgan C. Frank
    Date:11/13/2025

    Comments accompanying signature:  * Each Reporting Person disclaims beneficial ownership of the reported securities except to the extent of his, her or its pecuniary interest therein, and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of the securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose. To the extent that "ownership of 5 percent or less of a class" was indicated in Item 5, such response only applies to the Reporting Person(s) that indicated elsewhere herein that it beneficially owns five percent (5%) or less of the class.
    Exhibit Information

    Material to be Filed as Exhibit: Exhibit A - Joint Filing Agreement

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