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    SEC Form SCHEDULE 13G filed by Lexeo Therapeutics Inc.

    6/4/25 4:51:58 PM ET
    $LXEO
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $LXEO alert in real time by email



    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549


    SCHEDULE 13G


    UNDER THE SECURITIES EXCHANGE ACT OF 1934
    Lexeo Therapeutics, Inc.

    (Name of Issuer)


    Common Stock, $0.0001 par value per share

    (Title of Class of Securities)


    52886X107

    (CUSIP Number)


    05/28/2025

    (Date of Event Which Requires Filing of this Statement)


    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
    Checkbox not checked   Rule 13d-1(b)
    Checkbox checked   Rule 13d-1(c)
    Checkbox not checked   Rule 13d-1(d)






    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    Frazier Life Sciences Public Fund, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    3,730,419.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    3,730,419.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    3,730,419.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    6.8 %
    12Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 3,073,467 shares of Common Stock held directly by Frazier Life Sciences Public Fund, L.P. and (ii) 656,952 shares of Common Stock issuable to Frazier Life Sciences Public Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025. FHMLSP, L.P. is the general partner of Frazier Life Sciences Public Fund, L.P. and FHMLSP, L.L.C. is the general partner of FHMLSP, L.P. Patrick J. Heron, James N. Topper, Albert Cha and James Brush are the members of FHMLSP, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences Public Fund, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025 and (iii) 656,952 shares of Common Stock issuable to Frazier Life Sciences Public Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    FHMLSP, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    3,730,419.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    3,730,419.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    3,730,419.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    6.8 %
    12Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 3,073,467 shares of Common Stock held directly by Frazier Life Sciences Public Fund, L.P. and (ii) 656,952 shares of Common Stock issuable to Frazier Life Sciences Public Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025. FHMLSP, L.P. is the general partner of Frazier Life Sciences Public Fund, L.P. and FHMLSP, L.L.C. is the general partner of FHMLSP, L.P. Patrick J. Heron, James N. Topper, Albert Cha and James Brush are the members of FHMLSP, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences Public Fund, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025 and (iii) 656,952 shares of Common Stock issuable to Frazier Life Sciences Public Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    FHMLSP, L.L.C.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    3,730,419.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    3,730,419.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    3,730,419.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    6.8 %
    12Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 3,073,467 shares of Common Stock held directly by Frazier Life Sciences Public Fund, L.P. and (ii) 656,952 shares of Common Stock issuable to Frazier Life Sciences Public Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025. FHMLSP, L.P. is the general partner of Frazier Life Sciences Public Fund, L.P. and FHMLSP, L.L.C. is the general partner of FHMLSP, L.P. Patrick J. Heron, James N. Topper, Albert Cha and James Brush are the members of FHMLSP, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences Public Fund, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025 and (iii) 656,952 shares of Common Stock issuable to Frazier Life Sciences Public Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    Frazier Life Sciences Public Overage Fund, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    818,607.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    818,607.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    818,607.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    1.5 %
    12Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 624,804 shares of Common Stock held directly by Frazier Life Sciences Public Overage Fund, L.P. and (ii) 193,803 shares of Common Stock issuable to Frazier Life Sciences Public Overage Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025. FHMLSP Overage, L.P. is the general partner of Frazier Life Sciences Public Overage Fund, L.P. and FHMLSP Overage, L.L.C. is the general partner of FHMLSP Overage, L.P. Patrick J. Heron, James N. Topper, Albert Cha and James Brush are the members of FHMLSP Overage, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences Public Overage Fund, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025 and (iii) 193,803 shares of Common Stock issuable to Frazier Life Sciences Public Overage Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    FHMLSP Overage, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    818,607.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    818,607.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    818,607.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    1.5 %
    12Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 624,804 shares of Common Stock held directly by Frazier Life Sciences Public Overage Fund, L.P. and (ii) 193,803 shares of Common Stock issuable to Frazier Life Sciences Public Overage Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025. FHMLSP Overage, L.P. is the general partner of Frazier Life Sciences Public Overage Fund, L.P. and FHMLSP Overage, L.L.C. is the general partner of FHMLSP Overage, L.P. Patrick J. Heron, James N. Topper, Albert Cha and James Brush are the members of FHMLSP Overage, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences Public Overage Fund, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025 and (iii) 193,803 shares of Common Stock issuable to Frazier Life Sciences Public Overage Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    FHMLSP Overage, L.L.C.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    818,607.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    818,607.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    818,607.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    1.5 %
    12Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 624,804 shares of Common Stock held directly by Frazier Life Sciences Public Overage Fund, L.P. and (ii) 193,803 shares of Common Stock issuable to Frazier Life Sciences Public Overage Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025. FHMLSP Overage, L.P. is the general partner of Frazier Life Sciences Public Overage Fund, L.P. and FHMLSP Overage, L.L.C. is the general partner of FHMLSP Overage, L.P. Patrick J. Heron, James N. Topper, Albert Cha and James Brush are the members of FHMLSP Overage, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences Public Overage Fund, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025 and (iii) 193,803 shares of Common Stock issuable to Frazier Life Sciences Public Overage Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    Frazier Life Sciences X, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    114,541.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    114,541.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    114,541.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    0.2 %
    12Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 87,424 shares of Common Stock held directly by Frazier Life Sciences X, L.P. and (ii) 27,117 shares of Common Stock issuable to Frazier Life Sciences X, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025. FHMLS X, L.P. is the general partner of Frazier Life Sciences X, L.P. and FHMLS X, L.L.C. is the general partner of FHMLS X, L.P. Patrick J. Heron and James N. Topper are the members of FHMLS X, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences X, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025 and (iii) 27,117 shares of Common Stock issuable to Frazier Life Sciences X, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    FHMLS X, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    114,541.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    114,541.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    114,541.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    0.2 %
    12Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 87,424 shares of Common Stock held directly by Frazier Life Sciences X, L.P. and (ii) 27,117 shares of Common Stock issuable to Frazier Life Sciences X, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025. FHMLS X, L.P. is the general partner of Frazier Life Sciences X, L.P. and FHMLS X, L.L.C. is the general partner of FHMLS X, L.P. Patrick J. Heron and James N. Topper are the members of FHMLS X, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences X, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025 and (iii) 27,117 shares of Common Stock issuable to Frazier Life Sciences X, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    FHMLS X, L.L.C.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    114,541.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    114,541.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    114,541.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    0.2 %
    12Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 87,424 shares of Common Stock held directly by Frazier Life Sciences X, L.P. and (ii) 27,117 shares of Common Stock issuable to Frazier Life Sciences X, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025. FHMLS X, L.P. is the general partner of Frazier Life Sciences X, L.P. and FHMLS X, L.L.C. is the general partner of FHMLS X, L.P. Patrick J. Heron and James N. Topper are the members of FHMLS X, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences X, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025 and (iii) 27,117 shares of Common Stock issuable to Frazier Life Sciences X, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    Frazier Life Sciences XI, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    304,989.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    304,989.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    304,989.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    0.6 %
    12Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 232,784 shares of Common Stock held directly by Frazier Life Sciences XI, L.P. and (ii) 72,205 shares of Common Stock issuable to Frazier Life Sciences XI, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 16, 2025. FHMLS XI, L.P. is the general partner of Frazier Life Sciences XI, L.P. and FHMLS XI, L.L.C. is the general partner of FHMLS XI, L.P. Patrick J. Heron, James N. Topper and Daniel Estes are the members of FHMLS XI, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences XI, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025 and (iii) 72,205 shares of Common Stock issuable to Frazier Life Sciences XI, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    FHMLS XI, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    304,989.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    304,989.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    304,989.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    0.6 %
    12Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 232,784 shares of Common Stock held directly by Frazier Life Sciences XI, L.P. and (ii) 72,205 shares of Common Stock issuable to Frazier Life Sciences XI, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 16, 2025. FHMLS XI, L.P. is the general partner of Frazier Life Sciences XI, L.P. and FHMLS XI, L.L.C. is the general partner of FHMLS XI, L.P. Patrick J. Heron, James N. Topper and Daniel Estes are the members of FHMLS XI, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences XI, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025 and (iii) 72,205 shares of Common Stock issuable to Frazier Life Sciences XI, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    FHMLS XI, L.L.C.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    304,989.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    304,989.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    304,989.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    0.6 %
    12Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 232,784 shares of Common Stock held directly by Frazier Life Sciences XI, L.P. and (ii) 72,205 shares of Common Stock issuable to Frazier Life Sciences XI, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 16, 2025. FHMLS XI, L.P. is the general partner of Frazier Life Sciences XI, L.P. and FHMLS XI, L.L.C. is the general partner of FHMLS XI, L.P. Patrick J. Heron, James N. Topper and Daniel Estes are the members of FHMLS XI, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences XI, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025 and (iii) 72,205 shares of Common Stock issuable to Frazier Life Sciences XI, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    Frazier Life Sciences XII, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    532,256.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    532,256.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    532,256.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    1.0 %
    12Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 406,246 shares of Common Stock held directly by Frazier Life Sciences XII, L.P. and (ii) 126,010 shares of Common Stock issuable to Frazier Life Sciences XII, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025. FHMLS XII, L.P. is the general partner of Frazier Life Sciences XII, L.P. and FHMLS XII, L.L.C. is the general partner of FHMLS XII, L.P. Patrick J. Heron, James N. Topper and Daniel Estes are the members of FHMLS XII, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences XII, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025 and (iii) 126,010 shares of Common Stock issuable to Frazier Life Sciences XII, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    FHMLS XII, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    532,256.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    532,256.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    532,256.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    1.0 %
    12Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 406,246 shares of Common Stock held directly by Frazier Life Sciences XII, L.P. and (ii) 126,010 shares of Common Stock issuable to Frazier Life Sciences XII, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025. FHMLS XII, L.P. is the general partner of Frazier Life Sciences XII, L.P. and FHMLS XII, L.L.C. is the general partner of FHMLS XII, L.P. Patrick J. Heron, James N. Topper and Daniel Estes are the members of FHMLS XII, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences XII, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025 and (iii) 126,010 shares of Common Stock issuable to Frazier Life Sciences XII, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    FHMLS XII, L.L.C.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    532,256.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    532,256.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    532,256.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    1.0 %
    12Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 406,246 shares of Common Stock held directly by Frazier Life Sciences XII, L.P. and (ii) 126,010 shares of Common Stock issuable to Frazier Life Sciences XII, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025. FHMLS XII, L.P. is the general partner of Frazier Life Sciences XII, L.P. and FHMLS XII, L.L.C. is the general partner of FHMLS XII, L.P. Patrick J. Heron, James N. Topper and Daniel Estes are the members of FHMLS XII, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences XII, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025 and (iii) 126,010 shares of Common Stock issuable to Frazier Life Sciences XII, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    James N. Topper
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    UNITED STATES
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    5,500,812.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    5,500,812.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    5,500,812.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    9.9 %
    12Type of Reporting Person (See Instructions)

    IN

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 3,073,467 shares of Common Stock held directly by Frazier Life Sciences Public Fund, L.P., (ii) 656,952 shares of Common Stock issuable to Frazier Life Sciences Public Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, (iii) 624,804 shares of Common Stock held directly by Frazier Life Sciences Public Overage Fund, L.P., (iv) 193,803 shares of Common Stock issuable to Frazier Life Sciences Public Overage Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, (v) 87,424 shares of Common Stock held directly by Frazier Life Sciences X, L.P., (vi) 27,117 shares of Common Stock issuable to Frazier Life Sciences X, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, (vii) 232,784 shares of Common Stock held directly by Frazier Life Sciences XI, L.P., (viii) 72,205 shares of Common Stock issuable to Frazier Life Sciences XI, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, (ix) 406,246 shares of Common Stock held directly by Frazier Life Sciences XII, L.P. and (x) 126,010 shares of Common Stock issuable to Frazier Life Sciences XII, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025. FHMLSP, L.P. is the general partner of Frazier Life Sciences Public Fund, L.P. and FHMLSP, L.L.C. is the general partner of FHMLSP, L.P. Patrick J. Heron, James N. Topper, Albert Cha and James Brush are the members of FHMLSP, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences Public Fund, L.P. FHMLSP Overage, L.P. is the general partner of Frazier Life Sciences Public Overage Fund, L.P. and FHMLSP Overage, L.L.C. is the general partner of FHMLSP Overage, L.P. Patrick J. Heron, James N. Topper, Albert Cha and James Brush are the members of FHMLSP Overage, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences Public Overage Fund, L.P. FHMLS X, L.P. is the general partner of Frazier Life Sciences X, L.P. and FHMLS X, L.L.C. is the general partner of FHMLS X, L.P. Patrick J. Heron and James N. Topper are the members of FHMLS X, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences X, L.P. FHMLS XI, L.P. is the general partner of Frazier Life Sciences XI, L.P. and FHMLS XI, L.L.C. is the general partner of FHMLS XI, L.P. Patrick J. Heron, James N. Topper and Daniel Estes are the members of FHMLS XI, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences XI, L.P. FHMLS XII, L.P. is the general partner of Frazier Life Sciences XII, L.P. and FHMLS XII, L.L.C. is the general partner of FHMLS XII, L.P. Patrick J. Heron, James N. Topper and Daniel Estes are the members of FHMLS XII, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences XII, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025, (iii) 656,952 shares of Common Stock issuable to Frazier Life Sciences Public Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, (iv) 193,803 shares of Common Stock issuable to Frazier Life Sciences Public Overage Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, (v) 27,117 shares of Common Stock issuable to Frazier Life Sciences X, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, (vi) 72,205 shares of Common Stock issuable to Frazier Life Sciences XI, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, and (vii) 126,010 shares of Common Stock issuable to Frazier Life Sciences XII, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    Patrick J. Heron
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    UNITED STATES
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    5,500,812.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    5,500,812.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    5,500,812.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    9.9 %
    12Type of Reporting Person (See Instructions)

    IN

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 3,073,467 shares of Common Stock held directly by Frazier Life Sciences Public Fund, L.P., (ii) 656,952 shares of Common Stock issuable to Frazier Life Sciences Public Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, (iii) 624,804 shares of Common Stock held directly by Frazier Life Sciences Public Overage Fund, L.P., (iv) 193,803 shares of Common Stock issuable to Frazier Life Sciences Public Overage Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, (v) 87,424 shares of Common Stock held directly by Frazier Life Sciences X, L.P., (vi) 27,117 shares of Common Stock issuable to Frazier Life Sciences X, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, (vii) 232,784 shares of Common Stock held directly by Frazier Life Sciences XI, L.P., (viii) 72,205 shares of Common Stock issuable to Frazier Life Sciences XI, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, (ix) 406,246 shares of Common Stock held directly by Frazier Life Sciences XII, L.P. and (x) 126,010 shares of Common Stock issuable to Frazier Life Sciences XII, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025. FHMLSP, L.P. is the general partner of Frazier Life Sciences Public Fund, L.P. and FHMLSP, L.L.C. is the general partner of FHMLSP, L.P. Patrick J. Heron, James N. Topper, Albert Cha and James Brush are the members of FHMLSP, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences Public Fund, L.P. FHMLSP Overage, L.P. is the general partner of Frazier Life Sciences Public Overage Fund, L.P. and FHMLSP Overage, L.L.C. is the general partner of FHMLSP Overage, L.P. Patrick J. Heron, James N. Topper, Albert Cha and James Brush are the members of FHMLSP Overage, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences Public Overage Fund, L.P. FHMLS X, L.P. is the general partner of Frazier Life Sciences X, L.P. and FHMLS X, L.L.C. is the general partner of FHMLS X, L.P. Patrick J. Heron and James N. Topper are the members of FHMLS X, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences X, L.P. FHMLS XI, L.P. is the general partner of Frazier Life Sciences XI, L.P. and FHMLS XI, L.L.C. is the general partner of FHMLS XI, L.P. Patrick J. Heron, James N. Topper and Daniel Estes are the members of FHMLS XI, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences XI, L.P. FHMLS XII, L.P. is the general partner of Frazier Life Sciences XII, L.P. and FHMLS XII, L.L.C. is the general partner of FHMLS XII, L.P. Patrick J. Heron, James N. Topper and Daniel Estes are the members of FHMLS XII, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences XII, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025, (iii) 656,952 shares of Common Stock issuable to Frazier Life Sciences Public Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, (iv) 193,803 shares of Common Stock issuable to Frazier Life Sciences Public Overage Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, (v) 27,117 shares of Common Stock issuable to Frazier Life Sciences X, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, (vi) 72,205 shares of Common Stock issuable to Frazier Life Sciences XI, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, and (vii) 126,010 shares of Common Stock issuable to Frazier Life Sciences XII, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    Albert Cha
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    UNITED STATES
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    4,549,026.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    4,549,026.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    4,549,026.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    8.3 %
    12Type of Reporting Person (See Instructions)

    IN

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 3,073,467 shares of Common Stock held directly by Frazier Life Sciences Public Fund, L.P., (ii) 656,952 shares of Common Stock issuable to Frazier Life Sciences Public Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, (iii) 624,804 shares of Common Stock held directly by Frazier Life Sciences Public Overage Fund, L.P., and (iv) 193,803 shares of Common Stock issuable to Frazier Life Sciences Public Overage Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025. FHMLSP, L.P. is the general partner of Frazier Life Sciences Public Fund, L.P. and FHMLSP, L.L.C. is the general partner of FHMLSP, L.P. Patrick J. Heron, James N. Topper, Albert Cha and James Brush are the members of FHMLSP, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences Public Fund, L.P. FHMLSP Overage, L.P. is the general partner of Frazier Life Sciences Public Overage Fund, L.P. and FHMLSP Overage, L.L.C. is the general partner of FHMLSP Overage, L.P. Patrick J. Heron, James N. Topper, Albert Cha and James Brush are the members of FHMLSP Overage, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences Public Overage Fund, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025, (iii) 656,952 shares of Common Stock issuable to Frazier Life Sciences Public Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, and (iv) 193,803 shares of Common Stock issuable to Frazier Life Sciences Public Overage Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    James Brush
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    UNITED STATES
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    4,549,026.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    4,549,026.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    4,549,026.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    8.3 %
    12Type of Reporting Person (See Instructions)

    IN

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 3,073,467 shares of Common Stock held directly by Frazier Life Sciences Public Fund, L.P., (ii) 656,952 shares of Common Stock issuable to Frazier Life Sciences Public Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, (iii) 624,804 shares of Common Stock held directly by Frazier Life Sciences Public Overage Fund, L.P., and (iv) 193,803 shares of Common Stock issuable to Frazier Life Sciences Public Overage Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025. FHMLSP, L.P. is the general partner of Frazier Life Sciences Public Fund, L.P. and FHMLSP, L.L.C. is the general partner of FHMLSP, L.P. Patrick J. Heron, James N. Topper, Albert Cha and James Brush are the members of FHMLSP, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences Public Fund, L.P. FHMLSP Overage, L.P. is the general partner of Frazier Life Sciences Public Overage Fund, L.P. and FHMLSP Overage, L.L.C. is the general partner of FHMLSP Overage, L.P. Patrick J. Heron, James N. Topper, Albert Cha and James Brush are the members of FHMLSP Overage, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences Public Overage Fund, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025, (iii) 656,952 shares of Common Stock issuable to Frazier Life Sciences Public Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, and (iv) 193,803 shares of Common Stock issuable to Frazier Life Sciences Public Overage Fund, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    CUSIP No.
    52886X107


    1Names of Reporting Persons

    Daniel Estes
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    UNITED STATES
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    837,245.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    837,245.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    837,245.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    1.5 %
    12Type of Reporting Person (See Instructions)

    IN

    Comment for Type of Reporting Person:  The shares listed in rows 6, 8 and 9 consist of (i) 232,784 shares of Common Stock held directly by Frazier Life Sciences XI, L.P., (ii) 72,205 shares of Common Stock issuable to Frazier Life Sciences XI, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, (iii) 406,246 shares of Common Stock held directly by Frazier Life Sciences XII, L.P. and (iv) 126,010 shares of Common Stock issuable to Frazier Life Sciences XII, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025. FHMLS XI, L.P. is the general partner of Frazier Life Sciences XI, L.P. and FHMLS XI, L.L.C. is the general partner of FHMLS XI, L.P. Patrick J. Heron, James N. Topper and Daniel Estes are the members of FHMLS XI, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences XI, L.P. FHMLS XII, L.P. is the general partner of Frazier Life Sciences XII, L.P. and FHMLS XII, L.L.C. is the general partner of FHMLS XII, L.P. Patrick J. Heron, James N. Topper and Daniel Estes are the members of FHMLS XII, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences XII, L.P. The percentage listed in row 11 is calculated based the sum of (i) 33,196,997 shares of the Issuer's Common Stock outstanding as of May 12, 2025, as reported in the Issuer's Quarterly Report on Form 10-Q/A filed with the SEC on May 15, 2025, (ii) 20,790,120 shares of Common Stock that were sold by the Issuer in connection with its public offering as set forth as described in the Issuer's Current Report on Form 8-K filed with the SEC on May 27, 2025, (iii) 72,205 shares of Common Stock issuable to Frazier Life Sciences XI, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025, and (iv) 126,010 shares of Common Stock issuable to Frazier Life Sciences XII, L.P. pursuant to warrants and pre-funded warrants exercisable within 60 days of May 28, 2025.


    SCHEDULE 13G

    Item 1. 
    (a)Name of issuer:

    Lexeo Therapeutics, Inc.
    (b)Address of issuer's principal executive offices:

    345 PARK AVENUE SOUTH, FLOOR 6, NEW YORK, NY, 10010.
    Item 2. 
    (a)Name of person filing:

    The entities and persons filing this statement (collectively, the "Reporting Persons") are: Frazier Life Sciences Public Fund, L.P. ("FLSPF") FHMLSP, L.P. FHMLSP, L.L.C. Frazier Life Sciences Public Overage Fund, L.P. ("FLSPOF") FHMLSP Overage, L.P. FHMLSP Overage, L.L.C. Frazier Life Sciences X, L.P. ("FLS X") FHMLS X, L.P. FHMLS X, L.L.C. Frazier Life Sciences XI, L.P. ("FLS XI") FHMLS XI, L.P. FHMLS XI, L.L.C. Frazier Life Sciences XII, L.P. ("FLS XII") FHMLS XII, L.P. FHMLS XII, L.L.C. James N. Topper ("Topper") Patrick J. Heron ("Heron") Albert Cha ("Cha") James Brush ("Brush") Daniel Estes ("Estes" and together with Topper, Heron, Cha and Brush, the "Members")
    (b)Address or principal business office or, if none, residence:

    The address of the principal place of business for each of the Reporting Persons is: c/o Frazier Life Sciences Management, L.P. 1001 Page Mill Rd, Building 4, Suite B Palo Alto, CA 94304
    (c)Citizenship:

    Entities: FLSPF - Delaware, U.S.A. FHMLSP, L.P. - Delaware, U.S.A. FHMLSP, L.L.C. - Delaware, U.S.A. FLSPOF - Delaware, U.S.A. FHMLSP Overage, L.P. - Delaware, U.S.A. FHMLSP Overage, L.L.C. - Delaware, U.S.A. FLS X - Delaware, U.S.A. FHMLS X, L.P. - Delaware, U.S.A. FHMLS X, L.L.C. - Delaware, U.S.A. FLS XI - Delaware, U.S.A. FHMLS XI, L.P. - Delaware, U.S.A. FHMLS XI, L.L.C. - Delaware, U.S.A. FLS XII - Delaware, U.S.A. FHMLS XII, L.P. - Delaware, U.S.A. FHMLS XII, L.L.C. - Delaware, U.S.A. Individuals: Topper - United States Citizen Heron - United States Citizen Cha - United States Citizen Brush - United States Citizen Estes - United States Citizen
    (d)Title of class of securities:

    Common Stock, $0.0001 par value per share
    (e)CUSIP No.:

    52886X107
    Item 3.If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
    (a)Checkbox not checked   Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
    (b)Checkbox not checked   Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
    (c)Checkbox not checked   Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
    (d)Checkbox not checked   Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
    (e)Checkbox not checked   An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
    (f)Checkbox not checked   An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
    (g)Checkbox not checked   A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
    (h)Checkbox not checked   A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
    (i)Checkbox not checked   A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
    (j)Checkbox not checked   A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
           please specify the type of institution:
    (k)Checkbox not checked   Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
     
    Item 4.Ownership
    (a)Amount beneficially owned:

    The information contained in row 9 of each Reporting Person's cover page to this Schedule 13G (including the footnotes thereto) is incorporated by reference.
    (b)Percent of class:

    The information contained in row 11 of each Reporting Person's cover page to this Schedule 13G (including the footnotes thereto) is incorporated by reference. Due to field limitations of the EDGAR filing system, the percentages listed in Row 11 of Topper's and Heron's cover pages have been rounded down from 9.99% to 9.9%.
    (c)Number of shares as to which the person has:
     (i) Sole power to vote or to direct the vote:

    The information contained in row 5 of each Reporting Person's cover page to this Schedule 13G is incorporated by reference.

     (ii) Shared power to vote or to direct the vote:

    The information contained in row 6 of each Reporting Person's cover page to this Schedule 13G (including the footnotes thereto) is incorporated by reference.

     (iii) Sole power to dispose or to direct the disposition of:

    The information contained in row 7 of each Reporting Person's cover page to this Schedule 13G is incorporated by reference.

     (iv) Shared power to dispose or to direct the disposition of:

    The information contained in row 8 of each Reporting Person's cover page to this Schedule 13G (including the footnotes thereto) is incorporated by reference.

    Item 5.Ownership of 5 Percent or Less of a Class.
     
    Item 6.Ownership of more than 5 Percent on Behalf of Another Person.
     
    Not Applicable
    Item 7.Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
     
    Not Applicable
    Item 8.Identification and Classification of Members of the Group.
     
    Not Applicable
    Item 9.Notice of Dissolution of Group.
     
    Not Applicable

    Item 10.Certifications:
     
    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

        SIGNATURE 
     
    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     
    Frazier Life Sciences Public Fund, L.P.
     
    Signature:/s/ Steve R. Bailey
    Name/Title:By Steve R. Bailey, CFO of FHMLSP, L.L.C., GP of FHMLSP, L.P., GP of Frazier Life Sciences Public Fund, L.P.
    Date:06/04/2025
     
    FHMLSP, L.P.
     
    Signature:/s/ Steve R. Bailey
    Name/Title:By Steve R. Bailey, CFO of FHMLSP, L.L.C., GP of FHMLSP, L.P.
    Date:06/04/2025
     
    FHMLSP, L.L.C.
     
    Signature:/s/ Steve R. Bailey
    Name/Title:By Steve R. Bailey, CFO of FHMLSP, L.L.C.
    Date:06/04/2025
     
    Frazier Life Sciences Public Overage Fund, L.P.
     
    Signature:/s/ Steve R. Bailey
    Name/Title:By Steve R. Bailey, CFO of FHMLSP Overage, L.L.C., GP of FHMLSP Overage, L.P., GP of Frazier Life Sciences Public Overage Fund, L.P.
    Date:06/04/2025
     
    FHMLSP Overage, L.P.
     
    Signature:/s/ Steve R. Bailey
    Name/Title:By Steve R. Bailey, CFO of FHMLSP Overage, L.L.C., GP of FHMLSP Overage, L.P.
    Date:06/04/2025
     
    FHMLSP Overage, L.L.C.
     
    Signature:/s/ Steve R. Bailey
    Name/Title:By Steve R. Bailey, CFO of FHMLSP Overage, L.L.C.
    Date:06/04/2025
     
    Frazier Life Sciences X, L.P.
     
    Signature:/s/ Steve R. Bailey
    Name/Title:By Steve R. Bailey, CFO of FHMLS X, L.L.C., GP of FHMLS X, L.P., GP of Frazier Life Sciences X, L.P.
    Date:06/04/2025
     
    FHMLS X, L.P.
     
    Signature:/s/ Steve R. Bailey
    Name/Title:By Steve R. Bailey, CFO of FHMLS X, L.L.C., GP of FHMLS X, L.P.
    Date:06/04/2025
     
    FHMLS X, L.L.C.
     
    Signature:/s/ Steve R. Bailey
    Name/Title:By Steve R. Bailey, CFO of FHMLS X, L.L.C.
    Date:06/04/2025
     
    Frazier Life Sciences XI, L.P.
     
    Signature:/s/ Steve R. Bailey
    Name/Title:By Steve R. Bailey, CFO of FHMLS XI, L.L.C., GP of FHMLS XI, L.P., GP of Frazier Life Sciences XI, L.P.
    Date:06/04/2025
     
    FHMLS XI, L.P.
     
    Signature:/s/ Steve R. Bailey
    Name/Title:By Steve R. Bailey, CFO of FHMLS XI, L.L.C., GP of FHMLS XI, L.P.
    Date:06/04/2025
     
    FHMLS XI, L.L.C.
     
    Signature:/s/ Steve R. Bailey
    Name/Title:By Steve R. Bailey, CFO of FHMLS XI, L.L.C.
    Date:06/04/2025
     
    Frazier Life Sciences XII, L.P.
     
    Signature:/s/ Gordon Empey
    Name/Title:By Gordon Empey, General Counsel of FHMLS XII, L.L.C., GP of FHMLS XII, L.P., GP of Frazier Life Sciences XII, L.P.
    Date:06/04/2025
     
    FHMLS XII, L.P.
     
    Signature:/s/ Gordon Empey
    Name/Title:By Gordon Empey, General Counsel of FHMLS XII, L.L.C., GP of FHMLS XII, L.P.
    Date:06/04/2025
     
    FHMLS XII, L.L.C.
     
    Signature:/s/ Gordon Empey
    Name/Title:By Gordon Empey, General Counsel of FHMLS XII, L.L.C.
    Date:06/04/2025
     
    James N. Topper
     
    Signature:/s/ Steve R. Bailey
    Name/Title:By Steve R. Bailey, Attorney-in-Fact for James N. Topper, pursuant to a Power of Attorney, a copy of which was filed with the SEC on July 31, 2017
    Date:06/04/2025
     
    Patrick J. Heron
     
    Signature:/s/ Steve R. Bailey
    Name/Title:By Steve R. Bailey, Attorney-in-Fact for Patrick J. Heron, pursuant to a Power of Attorney, a copy of which was filed with the SEC on July 31, 2017
    Date:06/04/2025
     
    Albert Cha
     
    Signature:/s/ Steve R. Bailey
    Name/Title:By Steve R. Bailey, Attorney-in-Fact for Albert Cha, pursuant to a Power of Attorney, a copy of which was filed with the SEC on August 16, 2021
    Date:06/04/2025
     
    James Brush
     
    Signature:/s/ Steve R. Bailey
    Name/Title:By Steve R. Bailey, Attorney-in-Fact for James Brush, pursuant to a Power of Attorney, a copy of which was filed with the SEC on August 16, 2021
    Date:06/04/2025
     
    Daniel Estes
     
    Signature:/s/ Steve R. Bailey
    Name/Title:By Steve R. Bailey, Attorney-in-Fact for Daniel Estes, pursuant to a Power of Attorney, a copy of which was filed with the SEC on April 18, 2022
    Date:06/04/2025
    Exhibit Information

    Exhibit 99.1 Joint Filing Agreement.

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