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    Septerna downgraded by Wells Fargo with a new price target

    2/18/25 8:55:10 AM ET
    $SEPN
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $SEPN alert in real time by email
    Wells Fargo downgraded Septerna from Overweight to Equal Weight and set a new price target of $14.00
    Get the next $SEPN alert in real time by email

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    Recent Analyst Ratings for
    $SEPN

    DatePrice TargetRatingAnalyst
    6/23/2025$26.00Buy
    H.C. Wainwright
    2/18/2025$14.00Overweight → Equal Weight
    Wells Fargo
    11/19/2024$38.00Overweight
    Analyst
    11/19/2024Buy
    TD Cowen
    11/19/2024$43.00Overweight
    Wells Fargo
    11/19/2024$50.00Overweight
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    Septerna Appoints Veteran Biotechnology Leader Keith Gottesdiener, M.D., to its Board of Directors

    SOUTH SAN FRANCISCO, Calif., Sept. 29, 2025 (GLOBE NEWSWIRE) -- Septerna, Inc. (NASDAQ: SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced the appointment of Keith Gottesdiener, M.D., to its board of directors. A seasoned biotechnology executive with over 30 years of experience advancing medicines from discovery through commercialization, Dr. Gottesdiener will serve as chairperson of a newly constituted R&D Committee of the Board. "Dr. Gottesdiener's exceptional track record of successfully advancing novel therapeutics from discovery through development to approval, combined with his deep expertise in reg

    9/29/25 4:01:00 PM ET
    $SEPN
    Biotechnology: Pharmaceutical Preparations
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    Septerna to Participate in Upcoming Investor Conferences

    SOUTH SAN FRANCISCO, Calif., Aug. 27, 2025 (GLOBE NEWSWIRE) -- Septerna, Inc. (NASDAQ:SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced that management will participate in the following upcoming investor conferences in September: Cantor Global Healthcare Conference 2025 Presentation on Wednesday, September 3, 2025, at 11:30 a.m. ET 2025 Wells Fargo Healthcare ConferenceFireside chat on Friday, September 5, 2025, at 8:45 a.m. ET Live webcasts of the presentations will be available in the investors section of the company's website at www.septerna.com. Replays will be archived for at least 30 days f

    8/27/25 8:00:00 AM ET
    $SEPN
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    Septerna Announces Dosing of the First Participants in Phase 1 Clinical Trial of SEP-631, an Oral Small Molecule MRGPRX2 Negative Allosteric Modulator for the Treatment of Mast Cell-Driven Diseases

    SOUTH SAN FRANCISCO, Calif., Aug. 21, 2025 (GLOBE NEWSWIRE) -- Septerna, Inc. (NASDAQ:SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced the dosing of the first participants in its Phase 1 clinical trial of SEP-631, a selective oral small molecule Mas-related G protein-coupled receptor X2 (MRGPRX2) negative allosteric modulator (NAM) being developed for the treatment of chronic spontaneous urticaria (CSU) and other mast cell-driven diseases. The Phase 1 single-ascending dose (SAD) and multiple-ascending dose (MAD) clinical trial will evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodyna

    8/21/25 8:00:00 AM ET
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    Septerna Inc. filed SEC Form 8-K: Regulation FD Disclosure

    8-K - Septerna, Inc. (0001984086) (Filer)

    9/29/25 4:31:50 PM ET
    $SEPN
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Septerna Inc. filed SEC Form 8-K: Regulation FD Disclosure

    8-K - Septerna, Inc. (0001984086) (Filer)

    9/3/25 7:00:21 AM ET
    $SEPN
    Biotechnology: Pharmaceutical Preparations
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    Septerna Inc. filed SEC Form 8-K: Regulation FD Disclosure

    8-K - Septerna, Inc. (0001984086) (Filer)

    8/21/25 8:33:01 AM ET
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    Director Ezekowitz Alan bought $92,270 worth of shares (13,319 units at $6.93), increasing direct ownership by 13% to 117,420 units (SEC Form 4)

    4 - Septerna, Inc. (0001984086) (Issuer)

    3/10/25 4:18:19 PM ET
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    Director Ezekowitz Alan bought $515,934 worth of shares (86,681 units at $5.95), increasing direct ownership by 498% to 104,101 units (SEC Form 4)

    4 - Septerna, Inc. (0001984086) (Issuer)

    3/6/25 9:02:51 PM ET
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    CEO and President Finer Jeffrey bought $96,961 worth of shares (17,000 units at $5.70), increasing direct ownership by 2% to 771,907 units (SEC Form 4)

    4 - Septerna, Inc. (0001984086) (Issuer)

    2/27/25 6:53:01 PM ET
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    SEC Form 4 filed by Director Gottesdiener Keith Michael

    4 - Septerna, Inc. (0001984086) (Issuer)

    9/29/25 4:59:05 PM ET
    $SEPN
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    SEC Form 3 filed by new insider Gottesdiener Keith Michael

    3 - Septerna, Inc. (0001984086) (Issuer)

    9/29/25 4:57:58 PM ET
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    SVP, Biological Sciences Klein Uwe exercised 23,008 shares at a strike of $4.10 (SEC Form 4)

    4 - Septerna, Inc. (0001984086) (Issuer)

    8/19/25 5:02:20 PM ET
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    H.C. Wainwright initiated coverage on Septerna with a new price target

    H.C. Wainwright initiated coverage of Septerna with a rating of Buy and set a new price target of $26.00

    6/23/25 8:09:11 AM ET
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    Septerna downgraded by Wells Fargo with a new price target

    Wells Fargo downgraded Septerna from Overweight to Equal Weight and set a new price target of $14.00

    2/18/25 8:55:10 AM ET
    $SEPN
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    Analyst initiated coverage on Septerna with a new price target

    Analyst initiated coverage of Septerna with a rating of Overweight and set a new price target of $38.00

    11/19/24 7:39:27 AM ET
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    Septerna Appoints Veteran Biotechnology Leader Keith Gottesdiener, M.D., to its Board of Directors

    SOUTH SAN FRANCISCO, Calif., Sept. 29, 2025 (GLOBE NEWSWIRE) -- Septerna, Inc. (NASDAQ: SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced the appointment of Keith Gottesdiener, M.D., to its board of directors. A seasoned biotechnology executive with over 30 years of experience advancing medicines from discovery through commercialization, Dr. Gottesdiener will serve as chairperson of a newly constituted R&D Committee of the Board. "Dr. Gottesdiener's exceptional track record of successfully advancing novel therapeutics from discovery through development to approval, combined with his deep expertise in reg

    9/29/25 4:01:00 PM ET
    $SEPN
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    Septerna Expands Leadership with Appointment of Industry Veteran Gil Labrucherie as Chief Financial Officer

    SOUTH SAN FRANCISCO, Calif., Jan. 06, 2025 (GLOBE NEWSWIRE) -- Septerna, Inc. (NASDAQ:SEPN), a clinical-stage biotech company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced the appointment of Gil Labrucherie, CFA, J.D., as Chief Financial Officer. Mr. Labrucherie is a seasoned biopharma executive with more than 25 years of senior leadership experience in finance and legal roles for public biopharmaceutical and technology companies. "We are excited to welcome Gil to the team," said Jeffrey Finer, M.D., Ph.D., Chief Executive Officer and Co-founder of Septerna. "His extensive expertise leading public company finance and capital strategy will be ins

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    SEC Form SC 13D filed by Septerna Inc.

    SC 13D - Septerna, Inc. (0001984086) (Subject)

    11/4/24 4:39:38 PM ET
    $SEPN
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    SEC Form SC 13G filed by Septerna Inc.

    SC 13G - Septerna, Inc. (0001984086) (Subject)

    11/4/24 4:15:38 PM ET
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    SEC Form SC 13G filed by Septerna Inc.

    SC 13G - Septerna, Inc. (0001984086) (Subject)

    11/1/24 4:27:45 PM ET
    $SEPN
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