Simulations Plus Announces New Research Project With The International Collaboration On Cosmetics Safety To Evaluate The Use Of Physiologically-Based Kinetic Modeling Approaches To Advance Animal-Free Science For Cosmetics And Other Non-Pharmaceutical Ingredients
Objective to define best practices for the use of novel PBK modeling strategies to support animal-free safety assessment of new chemicals
Simulations Plus, Inc. (NASDAQ:SLP) ("Simulations Plus"), a leading provider of biosimulation, simulation-enabled performance and intelligence solutions, and medical communications to the biopharma industry, today announced a newly funded research project with the International Collaboration on Cosmetics Safety (ICCS) to evaluate the use of physiologically-based kinetic (PBK) modeling approaches to advance animal-free science for cosmetics and other non-pharmaceutical ingredients.
In a competitive bidding process, Simulations Plus was selected for its proposal to establish workflows for probabilistic PBK modeling of new chemicals based on pharmacokinetic (PK) analogs. Simulations Plus will review ICCS-provided data, select target-source pairs based on similarity criteria, build PBK models for source chemicals, and apply these in virtual populations to predict exposure for target chemicals. The results and best practices will be published.