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    Spyre Therapeutics Inc. filed SEC Form 8-K: Results of Operations and Financial Condition, Financial Statements and Exhibits

    2/19/26 4:05:57 PM ET
    $SYRE
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $SYRE alert in real time by email
    syre-20260219
    false000163628200016362822026-02-192026-02-19

    UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
    WASHINGTON, D.C. 20549
    _______________________________________________________

    FORM 8-K
    _______________________________________________________
    CURRENT REPORT
    Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
    Date of Report (Date of earliest event reported): February 19, 2026
    _______________________________________________________
    SPYRE THERAPEUTICS, INC.
    (Exact name of Registrant as Specified in Its Charter)
    _______________________________________________________
    Delaware001-3772246-4312787
    (State or Other Jurisdiction
    of Incorporation)
    (Commission File Number)(IRS Employer
    Identification No.)
    221 Crescent Street
    Building 23
    Suite 105
     
    Waltham, MA
     
    02453
    (Address of Principal Executive Offices) (Zip Code)
    Registrant’s Telephone Number, Including Area Code: 617 651-5940
    Not Applicable
    (Former Name or Former Address, if Changed Since Last Report)
    _______________________________________________________
    Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
    oWritten communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
    oSoliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
    oPre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
    oPre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
    Securities registered pursuant to Section 12(b) of the Act:
    Title of each classTrading
    Symbol(s)
    Name of each exchange on which registered
    Common Stock, $0.0001 Par Value Per Share
    SYRE
    The Nasdaq Stock Market LLC
    (Nasdaq Global Select Market)
    Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).
    Emerging growth company o
    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. o
    Item 2.02 Results of Operations and Financial Condition.
    On February 19, 2026, Spyre Therapeutics, Inc. (the “Company”) issued a press release announcing its financial results for the fourth quarter and fiscal year ended December 31, 2025. A copy of the press release is furnished as Exhibit 99.1 to this report.
    The information in this Item 2.02, including Exhibit 99.1 to this report, shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference into any filing under the Exchange Act or under the Securities Act of 1933, as amended, except as shall be expressly set forth by specific reference in such filing.

    Item 9.01 Financial Statements and Exhibits.
    (d)Exhibits
    Exhibit Number
    Description
    99.1
    Press release issued by Spyre Therapeutics, Inc. regarding its financial results for the fourth quarter and fiscal year ended December 31, 2025, dated February 19, 2026.
    104Cover Page Interactive Data File (embedded within the Inline XBRL document)



    SIGNATURES
    Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
      
    SPYRE THERAPEUTICS, INC.
       
    Date:
    February 19, 2026
    By:
    /s/ Scott Burrows
       
    Scott Burrows
    Chief Financial Officer

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