Wednesday saw 59 companies set new 52-week lows.

Key Facts About Today's 52-Week Lows:

• The largest company by market cap to hit a new 52-week low was TC Energy (NYSE:TRP).
• China SXT Pharmaceuticals (NASDAQ:SXTC) was the smallest company by market cap to set a new 52-week low.
• AppHarvest (NASDAQ:APPH)'s stock fell the most, as it traded down 19.83% to reach a new 52-week low.
• XOMA (NASDAQ:XOMA)'s stock made the biggest bounce back, actually moving up 0.0% shortly after hitting a new 52-week low.

Stocks dropping to new 52-week lows on Wednesday:

• TC Energy (NYSE:TRP) shares were up 0.49% for the day, having made a 52-week low of $36.44.
• Apellis Pharmaceuticals (NASDAQ:APLS) stock dropped to a yearly low on Wednesday of $29.70. Shares traded up 4.98%.
• Cytokinetics (NASDAQ:CYTK) stock drifted up 0.34% on Wednesday morning to hit a new 52-week low of $31.81.
• Maravai LifeSciences (NASDAQ:MRVI) shares moved down 2.18% on Wednesday to hit a new 52-week low of $11.38, drifting down 2.18%.
• Monro (NASDAQ:MNRO) shares were down 2.67% for the day, having made a 52-week low of $37.25.
• Avidity Biosciences (NASDAQ:RNA) shares made a new 52-week low of $8.93 on Wednesday. The stock was down 1.75% for the day.
• Nexa Res (NYSE:NEXA) shares set a new 52-week low of $4.15. The stock traded up 1.18%.
• Vertex Energy (NASDAQ:VTNR) shares made a new 52-week low of $4.84 on Wednesday. The stock was up 1.71% for the day.
• Sharecare (NASDAQ:SHCR) shares were down 5.56% for the day, having made a 52-week low of $1.26.
• uniQure (NASDAQ:QURE) shares hit a yearly low of $9.39. The stock was down 0.32% on the session.
• PSQ Holdings (NYSE:PSQH) stock set a new 52-week low of $12.26 on Wednesday, moving down 12.69%.
• Stoke Therapeutics (NASDAQ:STOK) stock set a new 52-week low of $5.90 on Wednesday, moving down 0.7%.
• SWK Holdings (NASDAQ:SWKH) stock drifted up 0.12% on Wednesday morning to hit a new 52-week low of $16.07.
• NGM Biopharmaceuticals (NASDAQ:NGM) stock hit $2.34 on Wednesday morning, setting a new 52-week low for a change of down 0.63%.
• FibroGen (NASDAQ:FGEN) stock hit $1.84 on Wednesday morning, setting a new 52-week low for a change of down 5.33%.
• XOMA (NASDAQ:XOMA) stock achieved a new 52-week low on Wednesday morning, hitting $15.26 and moving 0.0% (flat).
• Complete Solaria (NASDAQ:CSLR) stock hit a yearly low of $4.56. The stock was down 6.12% for the day.
• Altimmune (NASDAQ:ALT) stock dropped to a yearly low on Wednesday of $2.95. Shares traded up 0.33%.
• Beyond Air (NASDAQ:XAIR) stock hit a new 52-week low of $3.44. The stock was down 1.0% on the session.
• ARB IOT Group (NASDAQ:ARBB) stock broke to a new 52-week low of $2.25 on Wednesday. Shares of the company traded down 6.52%.
• Carmell Therapeutics (NASDAQ:CTCX) stock achieved a new 52-week low on Wednesday morning, hitting $2.97 and moving down 14.93%.
• Candel Therapeutics (NASDAQ:CADL) stock set a new 52-week low of $1.10 on Wednesday, moving down 0.88%.
• Leap Therapeutics (NASDAQ:LPTX) stock set a new 52-week low of $2.54 on Wednesday, moving down 6.18%.
• Aptose Biosciences (NASDAQ:APTO) stock hit $4.01 on Wednesday morning, setting a new 52-week low for a change of down 0.37%.
• Gulf Resources (NASDAQ:GURE) shares set a new yearly low of $2.32 this morning. The stock was down 1.67% on the session.
• Acurx Pharmaceuticals (NASDAQ:ACXP) stock hit a new 52-week low of $1.89. The stock was down 2.58% on the session.
• Cosmos Health (NASDAQ:COSM) stock hit a new 52-week low of $1.66. The stock was 0.0% (flat) on the session.
• BioCardia (NASDAQ:BCDA) stock hit a new 52-week low of $0.99. The stock was down 2.39% on the session.
• Vaccinex (NASDAQ:VCNX) stock broke to a new 52-week low of $0.27 on Wednesday. Shares of the company traded up 0.18%.
• Flora Growth (NASDAQ:FLGC) stock drifted down 2.56% on Wednesday morning to hit a new 52-week low of $2.05.
• IronNet (NYSE:IRNT) shares moved down 2.58% on Wednesday to hit a new 52-week low of $0.11, drifting down 2.58%.
• ShiftPixy (NASDAQ:PIXY) shares fell to $1.05 on Wednesday, setting a new 52-week low with a shift of down 3.39%.
• 60 Degrees (NASDAQ:SXTP) stock hit a yearly low of $2.01. The stock was down 3.05% for the day.
• Tempest Therapeutics (NASDAQ:TPST) stock hit a yearly low of $0.95. The stock was down 5.11% for the day.
• Fangdd Network Group (NASDAQ:DUO) shares fell to $0.16 on Wednesday, setting a new 52-week low with a shift of down 4.35%.
• Sidus Space (NASDAQ:SIDU) shares set a new 52-week low of $0.17. The stock traded down 4.53%.
• Cyclerion Therapeutics (NASDAQ:CYCN) stock achieved a new 52-week low on Wednesday morning, hitting $2.95 and moving down 4.11%.
• Bio-Path Hldgs (NASDAQ:BPTH) shares set a new 52-week low of $0.85. The stock traded down 4.04%.
• Lixte Biotech Hldgs (NASDAQ:LIXT) stock set a new 52-week low of $3.59 on Wednesday, moving down 5.41%.
• Mallinckrodt (AMEX:MNK) shares fell to $0.41 on Wednesday, setting a new 52-week low with a shift of up 12.72%.
• Aceragen (NASDAQ:ACGN) stock hit a new 52-week low of $0.59. The stock was up 6.33% on the session.
• Jeffs Brands (NASDAQ:JFBR) shares hit a yearly low of $0.65. The stock was down 1.6% on the session.
• Adamis Pharmaceuticals (NASDAQ:ADMP) stock set a new 52-week low of $1.65 on Wednesday, moving up 0.26%.
• Shineco (NASDAQ:SISI) stock broke to a new 52-week low of $0.22 on Wednesday. Shares of the company traded down 2.61%.
• 180 Life Sciences (NASDAQ:ATNF) shares fell to $0.85 on Wednesday, setting a new 52-week low with a shift of down 12.75%.
• Avalo Therapeutics (NASDAQ:AVTX) stock drifted up 4.87% on Wednesday morning to hit a new 52-week low of $0.21.
• Salarius Pharmaceuticals (NASDAQ:SLRX) shares set a new yearly low of $0.85 this morning. The stock was down 1.15% on the session.
• Aditxt (NASDAQ:ADTX) stock drifted up 0.5% on Wednesday morning to hit a new 52-week low of $0.39.
• NeuBase Therapeutics (NASDAQ:NBSE) stock broke to a new 52-week low of $1.35 on Wednesday. Shares of the company traded down 1.36%.
• First Wave BioPharma (NASDAQ:FWBI) stock achieved a new 52-week low on Wednesday morning, hitting $0.55 and moving down 2.44%.
• Allarity Therapeutics (NASDAQ:ALLR) stock hit $2.78 on Wednesday morning, setting a new 52-week low for a change of up 0.71%.
• Esports Entertainment (NASDAQ:GMBL) stock drifted down 5.32% on Wednesday morning to hit a new 52-week low of $0.47.
• BitNile Metaverse (NASDAQ:BNMV) stock drifted down 5.68% on Wednesday morning to hit a new 52-week low of $0.80.
• China SXT Pharmaceuticals (NASDAQ:SXTC) stock dropped to a yearly low on Wednesday of $0.17. Shares traded up 0.21%.

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