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    Tempus Reports First Quarter 2025 Results

    5/6/25 4:01:00 PM ET
    $TEM
    Computer Software: Programming Data Processing
    Technology
    Get the next $TEM alert in real time by email

    Tempus AI, Inc. (NASDAQ:TEM), a technology company leading the adoption of AI to advance precision medicine and patient care, today reported financial results for the quarter ended March 31, 2025.

    • Revenue increased 75.4% year-over-year to $255.7 million in the first quarter of 2025
    • Quarterly gross profit increased 99.8% year-over-year, reaching $155.2 million with continued gross margin improvement in both Genomics and Data and services
    • Announced multi-year, strategic collaborations with AstraZeneca and Pathos to work together to build the largest multimodal foundation model in oncology, resulting in additional $200.0 million in data licensing and model development fees over the next 3 years
    • Increasing full year 2025 revenue guidance to $1.25 billion, representing approximately 80% growth year-over-year. Expect positive Adjusted EBITDA of $5 million for full year 2025, increasing approximately $110 million over 2024

    "The business is performing well with revenues growing, margins improving, and our costs remaining in check, allowing us to demonstrate significant year-over-year operating leverage," said Eric Lefkofsky, Founder and CEO of Tempus. "Our strategic investments in AI have us uniquely positioned to advance what is possible in diagnostics and drug development, as evidenced by our announcement to build the largest foundation model in oncology with AstraZeneca and Pathos. We believe this is just the beginning as more and more healthcare providers and life science companies embrace AI."

    First Quarter Summary Results

    • Quarterly revenue increased 75.4% year-over-year to $255.7 million in the first quarter of 2025.
    • Genomics contributed $193.8 million in revenue in the first quarter of 2025, growing 88.9% compared to the first quarter of 2024.
      • Oncology testing (legacy Tempus clinical) revenue delivered $119.0 million, up 31.0% year-over-year in the first quarter of 2025, with approximately 20% volume growth.
      • Hereditary testing (legacy Ambry Genetics) contributed $63.5 million in revenue in the first quarter, with approximately 23% unit growth.
    • Revenue from Data and services totaled $61.9 million in the first quarter of 2025, delivering 43.2% growth versus the first quarter of 2024, led by Insights (data licensing), which grew 58.0% year-over-year.
    • Generated $155.2 million in quarterly gross profit, reflecting a 99.8% improvement year-over-year.
    • Reported a net loss of ($68.0 million) in the first quarter of 2025, including $28.2 million in stock compensation expense and related employer payroll taxes and fair value losses of $31.8 million related to our marketable equity securities, compared to a net loss of ($64.7 million) in the first quarter of 2024.
    • Adjusted EBITDA of ($16.2 million) in the first quarter of 2025 compared to ($43.9 million) in the first quarter of 2024, an improvement of $27.8 million year-over-year.

    First Quarter and Recent Operational Highlights

    • Announced multi-year, strategic collaborations with AstraZeneca and Pathos to work together to build a multimodal foundation model in oncology, which include $200.0 million in additional data licensing and model development fees to Tempus over the next 3 years.
    • Completed the acquisition of Ambry Genetics on February 3, 2025.
    • Disclosed a collaboration with Illumina combining its AI technologies with Tempus' comprehensive multimodal data platform to train genomic algorithms and accelerate clinical adoption of molecular testing.
    • Reported the acquisition of Deep 6 AI, broadening Tempus's reach and enhancing applications like Next and TIME.
    • Launched olivia, an AI-enabled personal health concierge app for patients nationally.
    • Nationally launched xT CDx with ADLT pricing established at $4,500 per test.

    First Quarter Financial Results

     

     

    Three Months Ended March 31,

     

     

     

     

     

     

    2025

     

     

    2024

     

     

    Change

     

     

     

    (in thousands, except percentages and per share amounts)

     

     

     

     

     

     

    (unaudited)

     

     

     

     

    Revenue

     

    $

    255,737

     

     

    $

    145,820

     

     

     

    75.4

    %

    Gross profit

     

    $

    155,203

     

     

    $

    77,697

     

     

     

    99.8

    %

    Loss from operations

     

    $

    (68,689

    )

     

    $

    (53,274

    )

     

    NM(1)

     

    Non-GAAP loss from operations

     

    $

    (25,777

    )

     

    $

    (53,274

    )

     

     

    51.6

    %

    Net loss

     

    $

    (68,037

    )

     

    $

    (64,743

    )

     

    NM(1)

     

    Adjusted EBITDA

     

    $

    (16,174

    )

     

    $

    (43,926

    )

     

     

    63.2

    %

    Net loss per share attributable to common shareholders, basic and diluted

     

    $

    (0.40

    )

     

    $

    (1.47

    )

     

     

    72.8

    %

    Non-GAAP net loss per share

     

    $

    (0.24

    )

     

    $

    (1.03

    )

     

     

    76.3

    %

    ____________

    (1)

    Not meaningful due to the impact of including stock compensation expense and related employer payroll taxes

    Financial Outlook and Guidance

    Tempus now expects full year 2025 revenue of approximately $1.25 billion for the consolidated Tempus and Ambry Genetics business, which represents approximately 80% annual growth, and Adjusted EBITDA of $5 million for full year 2025, an improvement of approximately $110 million over 2024.

    For additional information on the quarter, including a letter from our CEO and CFO, please visit our investors relations site at investors.tempus.com.

    Webcast and Conference Call Information

    A conference call and webcast will begin today, May 6, 2025 after market close at 4:30 p.m. Eastern Time. Interested parties may access details at:

    Conference ID: 4680302

    Domestic Dial-in Number: (888) 672-2415

    International Dial-in Number: (646) 307-1952

    Live webcast: https://edge.media-server.com/mmc/p/b4nkd33c/

    The webcast may be accessed on the company's investor relations website at investors.tempus.com. For those unable to listen to the live webcast, a recording will be made available on the company's website after the event and will be accessible for one year. Visit the investor relations website to find the company's latest deck, and commentary on the quarter by Eric Lefkofsky, Founder and CEO and Jim Rogers, CFO, which will be discussed on the conference call and webcast.

    About Tempus

    Tempus is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare. With one of the world's largest libraries of multimodal data, and an operating system to make that data accessible and useful, Tempus provides AI-enabled precision medicine solutions to physicians to deliver personalized patient care and in parallel facilitates discovery, development and delivery of optimal therapeutics. The goal is for each patient to benefit from the treatment of others who came before by providing physicians with tools that learn as the company gathers more data. For more information, visit tempus.com.

    Non-GAAP Financial Measures

    In addition to the financial information presented in this release in accordance with accounting principles generally accepted in the United States of America (GAAP), Tempus also presents adjusted non-GAAP financial measures.

    Non-GAAP gross profit is defined as GAAP gross profit, excluding stock-based compensation expense and employer payroll tax related to stock-based compensation (collectively, the "stock-based compensation adjustments"). Non-GAAP gross margin is defined as gross profit, excluding the stock-based compensation adjustments, as a percentage of revenue. Non-GAAP operating expenses are calculated as the sum of technology research and development expense, research and development expense, and selling, general and administrative expense, excluding the stock-based compensation adjustments, acquisition-related expenses, and amortization of intangibles due to acquisition. Non-GAAP loss from operations is defined as loss from operations, adjusted to exclude (i) stock-based compensation expense, (ii) employer payroll tax related to stock-based compensation expense, (iii) acquisition-related expenses, and (iv) amortization of intangibles due to acquisition. Non-GAAP net loss is defined as net loss, adjusted to exclude (i) changes in fair value of our warrant liability, warrant asset, marketable equity securities, contingent consideration liabilities and indemnity-related holdback liabilities, (ii) stock-based compensation expense, (iii) employer payroll tax related to stock-based compensation expense, (iv) acquisition-related expenses, (v) amortization of intangibles due to acquisition, (vi) losses on equity method investments, (vii) (benefit from) provision for income taxes, and (viii) amortization of deferred other income from our IP License Agreement with SB Tempus. Non-GAAP net loss per share is defined as non-GAAP net loss divided by weighted average common shares outstanding, basic and diluted.

    Adjusted EBITDA is defined as net loss, adjusted to exclude (i) interest income, (ii) interest expense, (iii) depreciation and amortization, (iv) (benefit from) provision for income taxes, (v) losses on equity method investments, (vi) changes in fair value of our warrant liability, warrant asset, marketable equity securities, contingent consideration liabilities and indemnity-related holdback liabilities, (vii) stock-based compensation expense, (viii) employer payroll tax related to stock-based compensation expense, (ix) acquisition related expenses, and (x) amortization of deferred other income from our IP License Agreement with SB Tempus.

    Tempus believes these non-GAAP financial measures are useful to investors and others because they allow for additional information with respect to financial measures used by management in its financial and operational decision-making and they may be used by institutional investors and the analyst community to help them analyze the health of Tempus' business. In particular, Adjusted EBITDA is a key measurement used by Tempus management to make operating decisions, including those related to analyzing operating expenses, evaluating performance, and performing strategic planning and annual budgeting. However, there are a number of limitations related to the use of non-GAAP financial measures, and these non-GAAP measures should be considered in addition to, not as a substitute for or in isolation from, our financial results prepared in accordance with GAAP. Other companies, including companies in our industry, may calculate these non-GAAP financial measures differently or not at all, which reduces their usefulness as comparative measures.

    Tempus does not provide guidance for net loss, the most directly comparable GAAP measure to EBITDA and Adjusted EBITDA, and similarly cannot provide a reconciliation between Tempus' forecasted Adjusted EBITDA and net loss without unreasonable effort due to the unavailability of reliable estimates for certain components of net income (loss) and the respective reconciliations. These forecasted items are not within Tempus' control, may vary greatly between periods, and could significantly impact future financial results.

    Other Key Metrics

    Total Remaining Contract Value (TCV) is equal to the total potential value of signed contracts and assumes the exercise of all contract options, all discretionary opt-ins, and no early termination. Remaining TCV excludes any revenue recognized to date on these contracts or any future adjustments made to the contractual value as a result of amendments or terminations.

    Net Revenue Retention compares the annual Insights product revenue generated from all customers that made an Insights purchase in one year to the annual Insights product revenue generated from the same cohort of customers in the subsequent year.

    Forward Looking Statements

    This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended (the "Securities Act"), and Section 21E of the Securities Exchange Act of 1934, as amended, about Tempus and its industry that involve substantial risks and uncertainties. All statements other than statements of historical facts contained in this press release are forward-looking statements, including, but not limited to, Tempus' expected financial results for full year 2025; the expectation that the collaborations with AstraZeneca and Pathos AI will result in the largest multimodal foundation model in oncology; and whether investments in AI will transform what is possible in diagnostics and research. In some cases, you can identify forward-looking statements because they contain words such as "anticipate," "believe," "contemplate," "continue," "could," "estimate," "expect," "going to," "intend," "may," "plan," "potential," "predict," "project," "should," "target," "will," or "would" or the negative of these words or other similar terms or expressions. Tempus cautions you that the foregoing may not include all of the forward-looking statements made in this press release.

    You should not rely on forward-looking statements as predictions of future events. Tempus has based the forward-looking statements contained in this press release primarily on its current expectations and projections about future events and trends that it believes may affect Tempus' business, financial condition, results of operations and prospects. These forward-looking statements are subject to risks and uncertainties related to: the intended use of Tempus' products and services; Tempus' financial performance; the ability to attract and retain customers and partners; managing Tempus' growth and future expenses; competition and new market entrants; compliance with new laws, regulations and executive actions, including any evolving regulations in the artificial intelligence space; the ability to maintain, protect and enhance Tempus' intellectual property; the ability to attract and retain qualified team members and key personnel; the ability to repay or refinance outstanding debt, or to access additional financing; future acquisitions, divestitures or investments, including Tempus' ability to realize the expected benefits of the acquisition of Ambry Genetics and Deep 6 AI; the potential adverse impact of climate change, natural disasters, health epidemics, macroeconomic conditions, and war or other armed conflict, as well as risks, uncertainties, and other factors described in the section titled "Risk Factors" in Tempus' Form 10-K for the year ended December 31, 2024, filed with the Securities and Exchange Commission ("the SEC") on February 24, 2025, as well as in other filings Tempus may make with the SEC in the future. In addition, any forward-looking statements contained in this press release are based on assumptions that Tempus believes to be reasonable as of this date. Tempus undertakes no obligation to update any forward-looking statements to reflect events or circumstances after the date of this press release or to reflect new information or the occurrence of unanticipated events, except as required by law.

     

     

    Tempus AI, Inc.

    CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS

    (Unaudited)

    (in thousands, except per share amounts)

     

     

     

    Three Months Ended March 31,

     

     

     

    2025

     

     

    2024

     

    Net revenue

     

     

     

     

     

     

    Genomics

     

    $

    193,804

     

     

    $

    102,569

     

    Data and services

     

     

    61,933

     

     

     

    43,251

     

    Total net revenue

     

    $

    255,737

     

     

    $

    145,820

     

    Cost and operating expenses

     

     

     

     

     

     

    Cost of revenues, genomics

     

     

    84,783

     

     

     

    52,835

     

    Cost of revenues, data and services

     

     

    15,751

     

     

     

    15,288

     

    Technology research and development

     

     

    33,391

     

     

     

    27,067

     

    Research and development

     

     

    35,874

     

     

     

    24,340

     

    Selling, general and administrative

     

     

    154,627

     

     

     

    79,564

     

    Total cost and operating expenses

     

     

    324,426

     

     

     

    199,094

     

    Loss from operations

     

    $

    (68,689

    )

     

    $

    (53,274

    )

    Interest income

     

     

    1,813

     

     

     

    1,031

     

    Interest expense

     

     

    (18,003

    )

     

     

    (13,238

    )

    Other (expense) income, net

     

     

    (27,455

    )

     

     

    749

     

    Loss before benefit from (provision for) income taxes

     

    $

    (112,334

    )

     

    $

    (64,732

    )

    Benefit from (provision for) income taxes

     

     

    46,180

     

     

     

    (11

    )

    Losses from equity method investments

     

     

    (1,883

    )

     

     

    —

     

    Net Loss

     

    $

    (68,037

    )

     

    $

    (64,743

    )

    Dividends on Series A, B, B-1, B-2, C, D, E, F, G, G-3, and G-4 preferred shares

     

     

    —

     

     

     

    (27,807

    )

    Cumulative undeclared dividends on Series C preferred shares

     

     

    —

     

     

     

    (506

    )

    Net loss attributable to common shareholders, basic and diluted

     

     

    (68,037

    )

     

     

    (93,056

    )

    Net loss per share attributable to common shareholders, basic and diluted

     

    $

    (0.40

    )

     

    $

    (1.47

    )

    Weighted-average shares outstanding used to compute net loss per share, basic and diluted

     

     

    170,506

     

     

     

    63,430

     

    Comprehensive Loss, net of tax

     

     

     

     

     

     

    Net loss

     

    $

    (68,037

    )

     

    $

    (64,743

    )

    Foreign currency translation adjustment

     

     

    4,598

     

     

     

    (56

    )

    Comprehensive loss

     

    $

    (63,439

    )

     

    $

    (64,799

    )

     

    Tempus AI, Inc.

    CONDENSED CONSOLIDATED BALANCE SHEETS

    (Unaudited)

    (in thousands, except share and per share amounts)

     

     

     

    March 31, 2025

     

     

    December 31, 2024

     

    Assets

     

     

     

     

     

     

    Current Assets

     

     

     

     

     

     

    Cash and cash equivalents

     

    $

    151,603

     

     

    $

    340,954

     

    Accounts receivable, net of allowances of $1,477 and $1,141 at March 31, 2025 and December 31, 2024, respectively

     

     

    262,613

     

     

     

    154,819

     

    Inventory

     

     

    50,485

     

     

     

    38,386

     

    Prepaid expenses and other current assets

     

     

    42,086

     

     

     

    26,135

     

    Marketable equity securities

     

     

    67,183

     

     

     

    107,309

     

    Total current assets

     

    $

    573,970

     

     

    $

    667,603

     

    Property and equipment, net

     

     

    93,536

     

     

     

    58,056

     

    Goodwill

     

     

    325,774

     

     

     

    73,343

     

    Intangible assets, net

     

     

    399,544

     

     

     

    11,716

     

    Investments and other assets

     

     

    14,811

     

     

     

    8,305

     

    Investment in joint venture

     

     

    94,153

     

     

     

    91,450

     

    Operating lease right-of-use assets

     

     

    39,626

     

     

     

    14,762

     

    Restricted cash

     

     

    1,723

     

     

     

    881

     

    Total Assets

     

    $

    1,543,137

     

     

    $

    926,116

     

     

     

     

     

     

     

     

    Liabilities, Convertible redeemable preferred stock, and Stockholders' equity

     

     

     

     

     

     

    Current Liabilities

     

     

     

     

     

     

    Accounts payable

     

     

    88,732

     

     

     

    53,804

     

    Accrued expenses

     

     

    129,238

     

     

     

    130,407

     

    Deferred revenue

     

     

    73,431

     

     

     

    75,981

     

    Deferred other income

     

     

    15,955

     

     

     

    15,955

     

    Other current liabilities

     

     

    18,194

     

     

     

    6,964

     

    Operating lease liabilities

     

     

    9,420

     

     

     

    6,459

     

    Accrued data licensing fees

     

     

    1,500

     

     

     

    1,500

     

    Total current liabilities

     

    $

    336,470

     

     

    $

    291,070

     

    Operating lease liabilities, less current portion

     

     

    47,567

     

     

     

    26,199

     

    Convertible promissory note

     

     

    233,620

     

     

     

    168,192

     

    Other long-term liabilities

     

     

    9,670

     

     

     

    15,980

     

    Revolving credit facility

     

     

    100,000

     

     

     

    —

     

    Interest payable

     

     

    1,470

     

     

     

    70,450

     

    Long-term debt, net

     

     

    467,144

     

     

     

    267,244

     

    Deferred other income, less current portion

     

     

    19,944

     

     

     

    23,932

     

    Deferred revenue, less current portion

     

     

    1,058

     

     

     

    6,710

     

    Total Liabilities

     

    $

    1,216,943

     

     

    $

    869,777

     

    Commitments and contingencies (Note 8)

     

     

     

     

     

     

    Convertible redeemable preferred stock, $0.0001 par value, 20,000,000 shares authorized at March 31, 2025 and December 31, 2024, respectively, no shares issued and outstanding at March 31, 2025 and December 31, 2024; aggregate liquidation preference of $0 at March 31, 2025 and December 31, 2024, respectively

     

    $

    —

     

     

    $

    —

     

    Stockholders' equity

     

     

     

     

     

     

    Class A Voting Common Stock, $0.0001 par value, 1,000,000,000 shares authorized at March 31, 2025 and December 31, 2024, respectively; 167,989,074 and 157,076,972 shares issued and outstanding at March 31, 2025 and December 31, 2024, respectively

     

     

    17

     

     

     

    16

     

    Class B Voting Common Stock, $0.0001 par value, 5,500,000 shares authorized at March 31, 2025 and December 31, 2024, respectively; 5,043,789 issued and outstanding at March 31, 2025 and December 31, 2024, respectively

     

     

    1

     

     

     

    1

     

    Non-voting Common Stock, $0.0001 par value, no shares authorized at March 31, 2025 and December 31, 2024, respectively; no shares issued and outstanding at March 31, 2025, and December 31, 2024, respectively

     

     

    —

     

     

     

    —

     

    Treasury Stock, 145,466 shares at March 31, 2025 and December 31, 2024, at cost

     

     

    (3,602

    )

     

     

    (3,602

    )

    Additional Paid-In Capital

     

     

    2,543,957

     

     

     

    2,210,664

     

    Accumulated Other Comprehensive Income

     

     

    4,692

     

     

     

    94

     

    Accumulated deficit

     

     

    (2,218,871

    )

     

     

    (2,150,834

    )

    Total Stockholders' equity

     

    $

    326,194

     

     

    $

    56,339

     

    Total Liabilities, Convertible redeemable preferred stock, and Stockholders' equity

     

    $

    1,543,137

     

     

    $

    926,116

     

     

    Tempus AI, Inc.

    CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

    (Unaudited)

    (in thousands, except per share amounts)

     

     

    Three Months Ended

    March 31,

     

     

    2025

     

     

    2024

     

    Operating activities

     

     

     

     

     

    Net loss

    $

    (68,037

    )

     

    $

    (64,743

    )

    Adjustments to reconcile net loss to net cash used in operating activities

     

     

     

     

     

    Change in fair value of warrant liability

    $

    —

     

     

    $

    800

     

    Stock-based compensation

     

    22,974

     

     

     

    —

     

    Loss (gain) on marketable equity securities

     

    31,805

     

     

     

    (6,246

    )

    Deferred income taxes

     

    (46,216

    )

     

     

    —

     

    Losses from equity method investments

     

    1,883

     

     

     

    —

     

    Amortization of original issue discount

     

    560

     

     

     

    345

     

    Amortization of deferred financing fees

     

    157

     

     

     

    128

     

    Change in fair value of contingent consideration

     

    —

     

     

     

    194

     

    Change in fair value of holdback liability

     

    46

     

     

     

    —

     

    Amortization of warrant contract asset

     

    —

     

     

     

    1,211

     

    Depreciation and amortization

     

    20,353

     

     

     

    9,189

     

    Provision for bad debt expense

     

    316

     

     

     

    219

     

    Change in fair value of warrant asset

     

    —

     

     

     

    4,700

     

    Non-cash operating lease costs

     

    2,089

     

     

     

    1,674

     

    Minimum accretion expense

     

    248

     

     

     

    70

     

    PIK interest added to principal

     

    3,274

     

     

     

    2,182

     

    Change in assets and liabilities

     

     

     

     

     

    Accounts receivable

     

    (45,175

    )

     

     

    (13,552

    )

    Inventory

     

    (911

    )

     

     

    (1,284

    )

    Prepaid expenses and other current assets

     

    (5,798

    )

     

     

    (5,729

    )

    Investments and other assets

     

    (3,358

    )

     

     

    1,294

     

    Accounts payable

     

    23,572

     

     

     

    (12,057

    )

    Deferred revenue

     

    (12,377

    )

     

     

    (15,974

    )

    Deferred other income

     

    (3,988

    )

     

     

    —

     

    Accrued data licensing fees

     

    (250

    )

     

     

    (2,750

    )

    Accrued expenses & other

     

    (27,606

    )

     

     

    (2,353

    )

    Interest payable

     

    3,508

     

     

     

    3,643

     

    Operating lease liabilities

     

    (2,693

    )

     

     

    (2,339

    )

    Net cash used in operating activities

    $

    (105,624

    )

     

    $

    (101,378

    )

     

     

     

     

     

     

    Investing activities

     

     

     

     

     

    Purchases of property and equipment

    $

    (2,074

    )

     

    $

    (6,108

    )

    Proceeds from sale of marketable equity securities

     

    8,316

     

     

     

    23,098

     

    Business combinations, net of cash acquired (Note 4)

     

    (380,762

    )

     

     

    —

     

    Purchases of capitalized software

     

    (1,298

    )

     

     

    —

     

    Net cash (used in) provided by investing activities

    $

    (375,818

    )

     

    $

    16,990

     

    Financing activities

     

     

     

     

     

    Payment of deferred offering costs

    $

    —

     

     

    $

    (565

    )

    Proceeds from revolving credit facility, net of original issue discount

     

    98,000

     

     

     

    —

     

    Proceeds from long-term debt, net of original issue discount

     

    196,000

     

     

     

    —

     

    Payment of deferred financing fees

     

    (958

    )

     

     

    —

     

    Payment of indemnity holdback related to acquisition

     

    —

     

     

     

    (813

    )

    Net cash provided by (used in) financing activities

    $

    293,042

     

     

    $

    (1,378

    )

    Effect of foreign exchange rates on cash

    $

    (109

    )

     

    $

    (49

    )

     

     

     

     

     

     

    Net decrease in Cash, Cash Equivalents and Restricted Cash

    $

    (188,509

    )

     

    $

    (85,815

    )

    Cash, cash equivalents and restricted cash, beginning of period

     

    341,835

     

     

     

    166,607

     

    Cash, cash equivalents and restricted cash, end of period

    $

    153,326

     

     

    $

    80,792

     

     

     

     

     

     

     

    Cash, Cash Equivalents and Restricted Cash are Comprised of:

     

     

     

     

     

    Cash and cash equivalents

    $

    151,603

     

     

    $

    79,942

     

    Restricted cash and cash equivalents

     

    1,723

     

     

     

    850

     

    Total cash, cash equivalents and restricted cash

    $

    153,326

     

     

    $

    80,792

     

     

     

     

     

     

     

    Supplemental disclosure of cash flow information

     

     

     

     

     

    Cash paid during the year for interest

    $

    10,849

     

     

    $

    6,980

     

    Cash paid for income taxes

    $

    —

     

     

    $

    —

     

     

     

     

     

     

     

    Supplemental disclosure of noncash investing and financing activities

     

     

     

     

     

    Dividends payable

    $

    —

     

     

    $

    2,966

     

    Purchases of property and equipment, accrued but not paid

    $

    7,003

     

     

    $

    1,379

     

    Deferred offering costs, accrued but not yet paid

    $

    —

     

     

    $

    4,071

     

    Redemption of convertible promissory note

    $

    7,060

     

     

    $

    6,391

     

    Non-voting common stock issued in connection with business combinations

    $

    —

     

     

    $

    344

     

    Class A Voting Common Stock issued in connection with business combinations

    $

    310,320

     

     

    $

    —

     

    Issuance of Series G-3 Preferred Stock

    $

    —

     

     

    $

    3,809

     

    Issuance of Series G-4 Preferred Stock

    $

    —

     

     

    $

    611

     

    Convertible promissory note principal reset due to amendment

    $

    72,488

     

     

    $

    —

     

     

    Tempus AI, Inc.

    RECONCILIATION OF GAAP TO NON-GAAP FINANCIAL MEASURES

    (Unaudited)

    (in thousands, except percentages and per share amounts)

     

    Genomics Gross Profit & Gross Margin

     

     

    Three Months Ended March 31,

     

     

     

    2025

     

     

    2024

     

    Genomics revenue

     

    $

    193,804

     

     

    $

    102,569

     

    Cost of revenues, genomics

     

     

    84,783

     

     

     

    52,835

     

    Gross profit, genomics

     

    $

    109,021

     

     

    $

    49,734

     

    Stock-based compensation expense

     

     

    1,035

     

     

     

    —

     

    Employer payroll tax related to stock-based compensation

     

     

    48

     

     

     

    —

     

    Non-GAAP gross profit, genomics

     

    $

    110,104

     

     

    $

    49,734

     

    Genomics gross margin

     

     

    56.3

    %

     

     

    48.5

    %

    Stock-based compensation expense

     

     

    0.5

    %

     

     

    0.0

    %

    Employer payroll tax related to stock-based compensation

     

     

    0.0

    %

     

     

    0.0

    %

    Non-GAAP gross margin, genomics

     

     

    56.8

    %

     

     

    48.5

    %

    Data and Services Gross Profit & Gross Margin

     

     

    Three Months Ended March 31,

     

     

     

    2025

     

     

    2024

     

    Data and services revenue

     

    $

    61,933

     

     

    $

    43,251

     

    Cost of revenues, data and services

     

     

    15,751

     

     

     

    15,288

     

    Gross profit, data and services

     

    $

    46,182

     

     

    $

    27,963

     

    Stock-based compensation expense

     

     

    611

     

     

     

    —

     

    Employer payroll tax related to stock-based compensation

     

     

    44

     

     

     

    —

     

    Non-GAAP gross profit, data and services

     

    $

    46,837

     

     

    $

    27,963

     

    Gross margin, data and services

     

     

    74.6

    %

     

     

    64.7

    %

    Stock-based compensation expense

     

     

    1.0

    %

     

     

    0.0

    %

    Employer payroll tax related to stock-based compensation

     

     

    0.1

    %

     

     

    0.0

    %

    Non-GAAP gross margin, data and services

     

     

    75.6

    %

     

     

    64.7

    %

    Total Gross Profit & Gross Margin

     

     

    Three Months Ended March 31,

     

     

     

    2025

     

     

    2024

     

    Net revenue

     

    $

    255,737

     

     

    $

    145,820

     

    Cost of revenues

     

     

    100,534

     

     

     

    68,123

     

    Gross profit

     

    $

    155,203

     

     

    $

    77,697

     

    Stock-based compensation expense

     

     

    1,646

     

     

     

    —

     

    Employer payroll tax related to stock-based compensation

     

     

    91

     

     

     

    —

     

    Non-GAAP gross profit

     

    $

    156,940

     

     

    $

    77,697

     

    Gross margin

     

     

    60.7

    %

     

     

    53.3

    %

    Stock-based compensation expense

     

     

    0.6

    %

     

     

    0.0

    %

    Employer payroll tax related to stock-based compensation

     

     

    0.0

    %

     

     

    0.0

    %

    Non-GAAP gross margin

     

     

    61.4

    %

     

     

    53.3

    %

    Operating Expenses

     

     

    Three Months Ended March 31,

     

     

     

    2025

     

     

    2024

     

    Technology research and development

     

    $

    33,391

     

     

    $

    27,067

     

    Stock-based compensation expense

     

     

    3,319

     

     

     

    —

     

    Employer payroll tax related to stock-based compensation

     

     

    261

     

     

     

    —

     

    Non-GAAP technology research and development

     

    $

    29,811

     

     

    $

    27,067

     

    Research and development

     

    $

    35,874

     

     

    $

    24,340

     

    Stock-based compensation expense

     

     

    1,982

     

     

     

    —

     

    Employer payroll tax related to stock-based compensation

     

     

    176

     

     

     

    —

     

    Non-GAAP research and development

     

    $

    33,716

     

     

    $

    24,340

     

    Selling, general and administrative

     

    $

    154,627

     

     

    $

    79,564

     

    Stock-based compensation expense

     

     

    16,027

     

     

     

    —

     

    Employer payroll tax related to stock-based compensation

     

     

    4,725

     

     

     

    —

     

    Acquisition related expenses

     

     

    3,529

     

     

     

    —

     

    Amortization of intangibles due to acquisition

     

     

    11,156

     

     

     

    —

     

    Non-GAAP selling, general and administrative

     

    $

    119,190

     

     

    $

    79,564

     

    Operating expenses

     

    $

    223,892

     

     

    $

    130,971

     

    Stock-based compensation expense

     

     

    21,328

     

     

     

    —

     

    Employer payroll tax related to stock-based compensation

     

     

    5,162

     

     

     

    —

     

    Acquisition related expenses

     

     

    3,529

     

     

     

    —

     

    Amortization of intangibles due to acquisition

     

     

    11,156

     

     

     

    —

     

    Non-GAAP operating expenses

     

    $

    182,717

     

     

    $

    130,971

     

    Earnings per Share

     

     

    Three Months Ended March 31,

     

     

     

    2025

     

     

    2024

     

    Net loss

     

    $

    (68,037

    )

     

    $

    (64,743

    )

    Fair value changes(1)

     

     

    31,850

     

     

     

    (590

    )

    Stock-based compensation expense

     

     

    22,974

     

     

     

    —

     

    Employer payroll tax related to stock-based compensation

     

     

    5,253

     

     

     

    —

     

    Acquisition related expenses(2)

     

     

    3,529

     

     

     

    —

     

    Amortization of intangibles due to acquisition

     

     

    11,156

     

     

     

    —

     

    Losses on equity method investments

     

     

    1,883

     

     

     

    —

     

    (Benefit from) provision for income taxes

     

     

    (46,180

    )

     

     

    11

     

    Amortization of technology license

     

     

    (3,989

    )

     

     

    —

     

    Non-GAAP net loss

     

    $

    (41,561

    )

     

    $

    (65,322

    )

    Non-GAAP net loss per share

     

    $

    (0.24

    )

     

    $

    (1.03

    )

    Weighted average common shares outstanding, basic and diluted

     

     

    170,506

     

     

     

    63,430

     

    (1)

    Fair value changes include gains and losses related to quarterly fair value adjustments of our warrant liability, warrant asset, marketable equity securities, contingent consideration liabilities, and indemnity-related holdback liabilities. 

    (2)

    Acquisition related expenses consist of legal, diligence, accounting, and financing costs incurred for the acquisitions of Ambry and Deep 6 during the three months ended March 31, 2025.

    Adjusted EBITDA

     

     

    Three Months Ended March 31,

     

     

     

    2025

     

     

    2024

     

    Net loss

     

    $

    (68,037

    )

     

    $

    (64,743

    )

    Interest income

     

     

    (1,813

    )

     

     

    (1,031

    )

    Interest expense

     

     

    18,003

     

     

     

    13,238

     

    Depreciation

     

     

    7,883

     

     

     

    6,269

     

    Amortization

     

     

    12,470

     

     

     

    2,920

     

    (Benefit from) provision for income taxes

     

     

    (46,180

    )

     

     

    11

     

    EBITDA

     

    $

    (77,674

    )

     

    $

    (43,336

    )

    Losses on equity method investments

     

     

    1,883

     

     

     

    —

     

    Fair value changes(1)

     

     

    31,850

     

     

     

    (590

    )

    Stock-based compensation expense

     

     

    22,974

     

     

     

    —

     

    Employer payroll tax related to stock-based compensation

     

     

    5,253

     

     

     

    —

     

    Acquisition related expenses(2)

     

     

    3,529

     

     

     

    —

     

    Amortization of technology license

     

     

    (3,989

    )

     

     

    —

     

    Adjusted EBITDA

     

    $

    (16,174

    )

     

    $

    (43,926

    )

    (1)

    Fair value changes include gains and losses related to quarterly fair value adjustments of our warrant liability, warrant asset, marketable equity securities, contingent consideration liabilities, and indemnity-related holdback liabilities. 

    (2)

    Acquisition related expenses consist of legal, diligence, accounting, and financing costs incurred for the acquisitions of Ambry and Deep 6 during the three months ended March 31, 2025.

    Loss from Operations

     

     

    Three Months Ended March 31,

     

     

     

    2025

     

     

    2024

     

    Loss from operations

     

    $

    (68,689

    )

     

    $

    (53,274

    )

    Stock-based compensation expense

     

     

    22,974

     

     

     

    —

     

    Employer payroll tax related to stock-based compensation

     

     

    5,253

     

     

     

    —

     

    Acquisition related expenses(1)

     

     

    3,529

     

     

     

    —

     

    Amortization of intangibles due to acquisition

     

     

    11,156

     

     

     

    —

     

    Non-GAAP loss from operations

     

    $

    (25,777

    )

     

    $

    (53,274

    )

    (1)

    Acquisition related expenses consist of legal, diligence, accounting, and financing costs incurred for the acquisitions of Ambry and Deep 6 during the three months ended March 31, 2025.

     

    View source version on businesswire.com: https://www.businesswire.com/news/home/20250506572067/en/

    Tempus Communications

    Erin Carron

    [email protected]

    Tempus Investor Relations

    Elizabeth Krutoholow

    [email protected]

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