TuHURA Biosciences And Kintara Therapeutics Announce Phase 1b Trial Of IFx-2.0 In Checkpoint Inhibitor Resistant Advanced Merkel Cell Carcinoma And Cutaneous Squamous Cell Carcinoma Results
TuHURA's lead candidate, IFx-2.0, was safe and well tolerated at once weekly dosing for 3 weeks
Eighty percent (80%) of ICI naïve patients with advanced MCC who failed to respond to pembrolizumab or avelumab therapy achieved a durable Complete Response (CR), pathologic CR or Partial Response (PR) following IFx-2.0 therapy and rechallenge with an anti-PD(L)-1 checkpoint inhibitor
Data presented at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting