Ventyx Biosciences Announces Preclinical Data For CNS-Penetrant NLRP3 Inhibitor VTX3232 Demonstrating Reversal Of Obesity And Improvements In Cardiometabolic And Inflammatory Markers
VTX3232 demonstrated improvements in body weight, systemic inflammatory biomarkers and cardiometabolic parameters in diet-induced obesity (DIO) mice
Additive effects were observed for VTX3232 in combination with the GLP-1 receptor agonist semaglutide across key endpoints compared to semaglutide or VTX3232 alone