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    Metsera Inc.

    Subscribe to $MTSR
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    IPO Year: 2025

    Exchange: NASDAQ

    Recent Analyst Ratings for Metsera Inc.

    DatePrice TargetRatingAnalyst
    9/30/2025$54.00Overweight → Equal Weight
    Wells Fargo
    9/9/2025$77.00Outperform
    Leerink Partners
    6/20/2025$65.00Overweight
    Wells Fargo
    2/25/2025$56.00Buy
    Guggenheim
    2/25/2025$38.00Buy
    BofA Securities
    2/25/2025Outperform
    Evercore ISI
    See more ratings

    Metsera Inc. Insider Purchases

    Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

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    Director Burow Kristina converted options into 23,530,631 shares and bought $39,999,996 worth of shares (2,222,222 units at $18.00) (SEC Form 4)

    4 - Metsera, Inc. (0002040807) (Issuer)

    2/3/25 7:15:35 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Director Berns Paul L bought $14,219,964 worth of shares (789,998 units at $18.00) and converted options into 7,523,682 shares (SEC Form 4)

    4 - Metsera, Inc. (0002040807) (Issuer)

    2/3/25 7:04:05 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Large owner Arch Venture Partners Xii, Llc converted options into 23,530,631 shares and bought $39,999,996 worth of shares (2,222,222 units at $18.00) (SEC Form 4)

    4 - Metsera, Inc. (0002040807) (Issuer)

    2/3/25 7:01:33 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Metsera Inc. Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

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    See Remark 1 Fmr Llc disposed of 5,593,464 shares, acquired 5,023,572 shares and sold $11,817 worth of shares (193 units at $61.23) (SEC Form 4)

    4 - Metsera, Inc. (0002040807) (Issuer)

    11/5/25 9:57:25 AM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    See Remark 1 Fmr Llc gifted 633,715 shares (SEC Form 4)

    4 - Metsera, Inc. (0002040807) (Issuer)

    10/8/25 3:35:08 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Amendment: See Remark 1 Fmr Llc acquired 1,107,547 shares (SEC Form 4)

    4/A - Metsera, Inc. (0002040807) (Issuer)

    9/12/25 4:09:01 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    See Remark 1 Fmr Llc sold $9,648 worth of shares (268 units at $36.00), disposed of 2,367,294 shares, acquired 2,151,820 shares and acquired 895 shares (SEC Form 4)

    4 - Metsera, Inc. (0002040807) (Issuer)

    9/4/25 2:58:55 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Director Pinto Joshua

    4 - Metsera, Inc. (0002040807) (Issuer)

    5/22/25 7:42:42 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Executive Chairman Meanwell Clive

    4 - Metsera, Inc. (0002040807) (Issuer)

    5/22/25 7:40:27 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Director Burow Kristina

    4 - Metsera, Inc. (0002040807) (Issuer)

    5/22/25 7:39:32 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Chief Financial Officer Visioli Christopher

    4 - Metsera, Inc. (0002040807) (Issuer)

    5/22/25 7:38:34 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Chief Legal Officer Lang Matthew

    4 - Metsera, Inc. (0002040807) (Issuer)

    5/22/25 7:37:47 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by President and CEO Bernard Christopher Whitten

    4 - Metsera, Inc. (0002040807) (Issuer)

    5/22/25 7:36:40 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Metsera Inc. Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

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    Metsera downgraded by Wells Fargo with a new price target

    Wells Fargo downgraded Metsera from Overweight to Equal Weight and set a new price target of $54.00

    9/30/25 8:33:25 AM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Leerink Partners initiated coverage on Metsera with a new price target

    Leerink Partners initiated coverage of Metsera with a rating of Outperform and set a new price target of $77.00

    9/9/25 7:59:28 AM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Wells Fargo initiated coverage on Metsera with a new price target

    Wells Fargo initiated coverage of Metsera with a rating of Overweight and set a new price target of $65.00

    6/20/25 7:54:18 AM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Guggenheim initiated coverage on Metsera with a new price target

    Guggenheim initiated coverage of Metsera with a rating of Buy and set a new price target of $56.00

    2/25/25 7:57:00 AM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    BofA Securities initiated coverage on Metsera with a new price target

    BofA Securities initiated coverage of Metsera with a rating of Buy and set a new price target of $38.00

    2/25/25 7:56:39 AM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Evercore ISI initiated coverage on Metsera

    Evercore ISI initiated coverage of Metsera with a rating of Outperform

    2/25/25 7:56:13 AM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Metsera Inc. SEC Filings

    View All

    SEC Form 8-K filed by Metsera Inc.

    8-K - Metsera, Inc. (0002040807) (Filer)

    11/5/25 8:07:40 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form DEFA14A filed by Metsera Inc.

    DEFA14A - Metsera, Inc. (0002040807) (Filer)

    11/4/25 11:51:22 AM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 8-K filed by Metsera Inc.

    8-K - Metsera, Inc. (0002040807) (Filer)

    11/4/25 10:47:59 AM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form DEFA14A filed by Metsera Inc.

    DEFA14A - Metsera, Inc. (0002040807) (Filer)

    11/3/25 12:20:05 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 8-K filed by Metsera Inc.

    8-K - Metsera, Inc. (0002040807) (Filer)

    11/3/25 12:17:16 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 8-K filed by Metsera Inc.

    8-K - Metsera, Inc. (0002040807) (Filer)

    10/31/25 9:13:10 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form DEFA14A filed by Metsera Inc.

    DEFA14A - Metsera, Inc. (0002040807) (Filer)

    10/31/25 9:14:49 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form SCHEDULE 13G filed by Metsera Inc.

    SCHEDULE 13G - Metsera, Inc. (0002040807) (Subject)

    10/31/25 11:05:39 AM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form DEFA14A filed by Metsera Inc.

    DEFA14A - Metsera, Inc. (0002040807) (Filer)

    10/30/25 10:49:07 AM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Metsera Inc. filed SEC Form 8-K: Other Events

    8-K - Metsera, Inc. (0002040807) (Filer)

    10/30/25 7:39:59 AM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Metsera Inc. Press Releases

    Fastest customizable press release news feed in the world

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    Pfizer and Metsera Enter into Merger Agreement Amendment; Metsera's Board of Directors Reaffirms Support of Merger with Pfizer

    Revised transaction values Metsera at up to $86.25 per shareMetsera's Board of Directors unanimously recommends that Metsera stockholders approve the adoption of the amended Pfizer merger agreement and approve the merger with PfizerTransaction creates real, certain and immediate value for Metsera's stockholders and ensures Metsera's important drug candidates can emerge as key competitors available to all patientsNEW YORK, Nov. 7, 2025 /PRNewswire/ -- Metsera, Inc. (NASDAQ:MTSR) today announced that it has entered into an amended merger agreement with Pfizer, pursuant to which Pfizer will acquire Metsera for up to $86.25 per share, consisting of $65.60 per share in cash and a contingent value

    11/7/25 9:32:00 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Metsera Issues Statement in Response to Litigation Ruling

    NEW YORK, Nov. 5, 2025 /PRNewswire/ -- Metsera, Inc. (NASDAQ:MTSR) ("Metsera" or the "Company") today issued the following statement in response to a ruling in the litigation filed against the Company by Pfizer: "Metsera is gratified by the Delaware Court of Chancery's decision to deny Pfizer's request for a temporary restraining order to block Metsera's Board of Directors from acting in the best interests of shareholders. Separately, Pfizer has reiterated it will continue to spuriously litigate. As we have previously noted, Pfizer's litigation arguments are nonsense. Metsera's Board of Directors will continue to stand firm on behalf of shareholders and patients." Disclosure Notice This rel

    11/5/25 7:17:00 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    /C O R R E C T I O N -- Metsera, Inc./

    In the news release, Metsera Receives Amended Proposal from Novo Nordisk; Metsera Declares Novo Nordisk Amended Proposal "Superior", issued 04-Nov-2025 by Metsera, Inc. over PR Newswire, we are advised by the company that the second paragraph, third sentence, should begin "Shortly thereafter,..." rather than "On the same day,...", and the third paragraph, first sentence, should read "...representing up to $24.00 per share in cash (up from $21.25)..." rather than "...representing up to $24.00 per share in cash (up from $22.50)..." as originally issued inadvertently. The complete, corrected release follows: Metsera Receives Amended Proposal from Novo Nordisk; Metsera Declares Novo Nordisk Ame

    11/4/25 9:09:00 AM ET
    $MTSR
    $NVO
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Metsera Receives Amended Proposal from Novo Nordisk; Metsera Declares Novo Nordisk Amended Proposal "Superior"

    Novo Nordisk Amended Proposal Values Metsera at up to $86.20 per Share, a Total of Approximately $10.0 Billion Superior to Revised Pfizer Proposal that Valued Metsera at up to $70.00 per Share, a Total of Approximately $8.1 Billion Pursuant to Pfizer Merger Agreement, Metsera and Pfizer May Negotiate Potential Adjustments for Two Business Days Pfizer Merger Agreement Remains in Effect; No Action Required by Metsera Shareholders NEW YORK, Nov. 4, 2025 /PRNewswire/ -- Metsera, Inc. (NASDAQ:MTSR) ("Metsera") today announced that its Board of Directors had determined, after consultation with its outside counsel and financial advisors, that a revised proposal that Metsera received from Novo Nord

    11/4/25 9:09:00 AM ET
    $MTSR
    $NVO
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Metsera Issues Statement in Response to Litigation

    NEW YORK, Nov. 3, 2025 /PRNewswire/ -- Metsera, Inc. (NASDAQ:MTSR) ("Metsera" or the "Company") today issued the following statement in response to litigation filed against the Company by Pfizer: "Pfizer is trying to litigate its way to buying Metsera for a lower price than Novo Nordisk. Metsera's Board of Directors will continue to stand firm on behalf of shareholders and patients. Pfizer's litigation arguments are nonsense, and Metsera will address them in court." Disclosure Notice  This release contains forward-looking information about, among other topics, Pfizer's proposed acquisition of Metsera, Pfizer's and Metsera's pipeline products, including their potential benefits, potential be

    11/3/25 11:02:00 AM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Metsera Issues Statement in Response to Litigation

    NEW YORK, Oct. 31, 2025 /PRNewswire/ -- Metsera, Inc. (NASDAQ:MTSR) ("Metsera" or the "Company") today issued the following statement in response to litigation filed against the Company by Pfizer: "Metsera disagrees with the allegations in Pfizer's complaint and will address them in the Delaware Court of Chancery."   Disclosure Notice  This release contains forward-looking information about, among other topics, Pfizer's proposed acquisition of Metsera, Pfizer's and Metsera's pipeline products, including their potential benefits, potential best-in-class status, differentiation, profile and dosing, potential clinical trials, and the anticipated timing of completion of the proposed acquisition

    10/31/25 6:24:00 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pfizer Receives Early Clearance from U.S. Federal Trade Commission for Metsera Acquisition

    Pfizer Inc. (NYSE:PFE) today announced the U.S. Federal Trade Commission has granted early termination of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976, as amended (the "HSR Act"), with respect to Pfizer's pending acquisition of Metsera (NASDAQ:MTSR). The termination of the waiting period under the HSR Act satisfies the regulatory review requirements under the previously announced proposed acquisition of Metsera, which was set to expire on November 7. About Pfizer: Breakthroughs That Change Patients' Lives At Pfizer, we apply science and our global resources to bring therapies to people that extend and significantly improve their lives. We strive to

    10/31/25 3:50:00 PM ET
    $MTSR
    $PFE
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Metsera Receives Unsolicited Proposal from Novo Nordisk

    Metsera Declares Novo Nordisk Proposal "Superior" Novo Nordisk Proposal Values Metsera at up to $77.75 per Share, a Total of Approximately $9 Billion Pursuant to Pfizer Merger Agreement, Metsera and Pfizer May Negotiate Potential Adjustments to Existing Transaction Pfizer Merger Agreement Remains in Effect; No Action Required by Metsera Shareholders NEW YORK, Oct. 30, 2025 /PRNewswire/ -- Metsera, Inc. (NASDAQ:MTSR) ("Metsera") today announced that its Board of Directors had determined, after consultation with its outside counsel and financial advisors, that an unsolicited proposal that Metsera received from Novo Nordisk A/S (Nasdaq Copenhagen: NOVO B) ("Novo Nordisk") to acquire Metsera (th

    10/30/25 7:07:00 AM ET
    $MTSR
    $NVO
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pfizer Addresses Proposal for Metsera

    Pfizer Inc. (NYSE:PFE) is aware of the reckless and unprecedented proposal by Novo Nordisk A/S (NYSE:NVO) to acquire Metsera, Inc. (NASDAQ:MTSR). It is an attempt by a company with a dominant market position to suppress competition in violation of law by taking over an emerging American challenger. It is also structured in a way to circumvent antitrust laws and carries substantial regulatory and executional risk. The proposal is illusory and cannot qualify as a superior proposal under Pfizer's agreement with Metsera, and Pfizer is prepared to pursue all legal avenues to enforce its rights under its agreement. As disclosed in Metsera's proxy, the Board of Metsera previously rejected Novo N

    10/30/25 6:57:00 AM ET
    $MTSR
    $NVO
    $PFE
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Metsera Reports Positive Phase 2b Results for First- and Best-in-Class Ultra-long Acting GLP-1 RA Candidate MET-097i, Enabling Rapid Transition into Phase 3

    Placebo-subtracted mean weight loss up to 14.1% after 28 weeks with no plateau Potential for best-in-class tolerability with minimal diarrhea signal, 13% nausea, and 11% vomiting High study and treatment retention in both VESPER-1 and VESPER-3 trials Data support Phase 3 initiation in late 2025 NEW YORK, Sept. 29, 2025 (GLOBE NEWSWIRE) -- Metsera, Inc. (NASDAQ: MTSR), today announced positive topline data from VESPER-1 and positive data from a planned interim analysis for tolerability of VESPER-3 – two Phase 2b trials of MET-097i, a first-in-class fully biased, ultra-long acting GLP-1 receptor agonist (RA) with potential for monthly dosing. In VESPER-1, MET-097i demonstrated me

    9/29/25 4:01:13 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Metsera Inc. Financials

    Live finance-specific insights

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    Pfizer and Metsera Enter into Merger Agreement Amendment; Metsera's Board of Directors Reaffirms Support of Merger with Pfizer

    Revised transaction values Metsera at up to $86.25 per shareMetsera's Board of Directors unanimously recommends that Metsera stockholders approve the adoption of the amended Pfizer merger agreement and approve the merger with PfizerTransaction creates real, certain and immediate value for Metsera's stockholders and ensures Metsera's important drug candidates can emerge as key competitors available to all patientsNEW YORK, Nov. 7, 2025 /PRNewswire/ -- Metsera, Inc. (NASDAQ:MTSR) today announced that it has entered into an amended merger agreement with Pfizer, pursuant to which Pfizer will acquire Metsera for up to $86.25 per share, consisting of $65.60 per share in cash and a contingent value

    11/7/25 9:32:00 PM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    /C O R R E C T I O N -- Metsera, Inc./

    In the news release, Metsera Receives Amended Proposal from Novo Nordisk; Metsera Declares Novo Nordisk Amended Proposal "Superior", issued 04-Nov-2025 by Metsera, Inc. over PR Newswire, we are advised by the company that the second paragraph, third sentence, should begin "Shortly thereafter,..." rather than "On the same day,...", and the third paragraph, first sentence, should read "...representing up to $24.00 per share in cash (up from $21.25)..." rather than "...representing up to $24.00 per share in cash (up from $22.50)..." as originally issued inadvertently. The complete, corrected release follows: Metsera Receives Amended Proposal from Novo Nordisk; Metsera Declares Novo Nordisk Ame

    11/4/25 9:09:00 AM ET
    $MTSR
    $NVO
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Metsera Receives Amended Proposal from Novo Nordisk; Metsera Declares Novo Nordisk Amended Proposal "Superior"

    Novo Nordisk Amended Proposal Values Metsera at up to $86.20 per Share, a Total of Approximately $10.0 Billion Superior to Revised Pfizer Proposal that Valued Metsera at up to $70.00 per Share, a Total of Approximately $8.1 Billion Pursuant to Pfizer Merger Agreement, Metsera and Pfizer May Negotiate Potential Adjustments for Two Business Days Pfizer Merger Agreement Remains in Effect; No Action Required by Metsera Shareholders NEW YORK, Nov. 4, 2025 /PRNewswire/ -- Metsera, Inc. (NASDAQ:MTSR) ("Metsera") today announced that its Board of Directors had determined, after consultation with its outside counsel and financial advisors, that a revised proposal that Metsera received from Novo Nord

    11/4/25 9:09:00 AM ET
    $MTSR
    $NVO
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Metsera Receives Unsolicited Proposal from Novo Nordisk

    Metsera Declares Novo Nordisk Proposal "Superior" Novo Nordisk Proposal Values Metsera at up to $77.75 per Share, a Total of Approximately $9 Billion Pursuant to Pfizer Merger Agreement, Metsera and Pfizer May Negotiate Potential Adjustments to Existing Transaction Pfizer Merger Agreement Remains in Effect; No Action Required by Metsera Shareholders NEW YORK, Oct. 30, 2025 /PRNewswire/ -- Metsera, Inc. (NASDAQ:MTSR) ("Metsera") today announced that its Board of Directors had determined, after consultation with its outside counsel and financial advisors, that an unsolicited proposal that Metsera received from Novo Nordisk A/S (Nasdaq Copenhagen: NOVO B) ("Novo Nordisk") to acquire Metsera (th

    10/30/25 7:07:00 AM ET
    $MTSR
    $NVO
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Pfizer to Acquire Metsera and its Next-Generation Obesity Portfolio

    Proposed acquisition to add four highly differentiated clinical-stage incretin and amylin programs to Pfizer's pipeline Transaction valued at $47.50 per Metsera share in cash upon closing, for an initial enterprise value of $4.9 billion with a CVR of up to $22.50 per share in additional payments Pfizer to host a public webcast at 8 am EDT today Pfizer Inc. (NYSE:PFE) and Metsera, Inc. (NASDAQ:MTSR) today announced the companies have entered into a definitive agreement under which Pfizer will acquire Metsera, a clinical-stage biopharmaceutical company accelerating the next generation of medicines for obesity and cardiometabolic diseases. The acquisition brings deep expertise and a

    9/22/25 6:45:00 AM ET
    $MTSR
    $PFE
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Metsera Announces Positive Phase 1 Data of First-in-Class Once-Monthly Amylin Candidate MET-233i

    Placebo-subtracted mean weight loss up to 8.4% at Day 36 19-day observed half-life supports once-monthly dosing as monotherapy and potential first-in-category monthly GLP-1 + Amylin combination Well-tolerated with no safety signals Company to host conference call and webcast today at 8:00 A.M. ET NEW YORK, June 09, 2025 (GLOBE NEWSWIRE) -- Metsera, Inc. (NASDAQ:MTSR), today announced positive topline data from the Phase 1 clinical trial of MET-233i, an ultra-long acting amylin analog engineered for class-leading durability, potency, and combinability with Metsera's fully-biased monthly GLP-1 receptor agonist candidate, MET-097i. In the study, MET-233i demonstrated up to 8.4% mean placeb

    6/9/25 7:00:00 AM ET
    $MTSR
    Biotechnology: Pharmaceutical Preparations
    Health Care