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    Protagenic Therapeutics Inc.

    Subscribe to $PTIX
    $PTIX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Protagenic Therapeutics, Inc., a pre-clinical biopharmaceutical company, engages in the discovery and development of therapeutics to treat stress-related neuropsychiatric and mood disorders. Its lead compound, PT00114 is a synthetic form of teneurin carboxy-terminal associated peptide, an endogenous brain signaling peptide that can dampen overactive stress responses. The company was founded in 2016 and is based in New York, New York.

    IPO Year:

    Exchange: NASDAQ

    Website: protagenic.com

    Recent Analyst Ratings for Protagenic Therapeutics Inc.

    DatePrice TargetRatingAnalyst
    10/29/2021$4.00Buy
    Maxim Group
    See more ratings

    Protagenic Therapeutics Inc. SEC Filings

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    • Protagenic Therapeutics Inc. filed SEC Form 8-K: Entry into a Material Definitive Agreement

      8-K - Protagenic Therapeutics, Inc.\new (0001022899) (Filer)

      5/20/25 11:48:02 AM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form DEFA14A filed by Protagenic Therapeutics Inc.

      DEFA14A - Protagenic Therapeutics, Inc.\new (0001022899) (Filer)

      5/19/25 4:59:33 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagenic Therapeutics Inc. filed SEC Form 8-K: Entry into a Material Definitive Agreement, Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Completion of Acquisition or Disposition of Assets, Unregistered Sales of Equity Securities, Material Modification to Rights of Security Holders, Leadership Update, Regulation FD Disclosure, Other Events, Financial Statements and Exhibits

      8-K - Protagenic Therapeutics, Inc.\new (0001022899) (Filer)

      5/19/25 8:19:09 AM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 10-Q filed by Protagenic Therapeutics Inc.

      10-Q - Protagenic Therapeutics, Inc.\new (0001022899) (Filer)

      5/13/25 3:22:08 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagenic Therapeutics Inc. filed SEC Form 8-K: Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits

      8-K - Protagenic Therapeutics, Inc.\new (0001022899) (Filer)

      5/5/25 6:05:20 AM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagenic Therapeutics Inc. filed SEC Form 8-K: Regulation FD Disclosure, Financial Statements and Exhibits

      8-K - Protagenic Therapeutics, Inc.\new (0001022899) (Filer)

      4/29/25 4:05:16 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagenic Therapeutics Inc. filed SEC Form 8-K: Submission of Matters to a Vote of Security Holders

      8-K - Protagenic Therapeutics, Inc.\new (0001022899) (Filer)

      4/18/25 1:39:42 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 10-K filed by Protagenic Therapeutics Inc.

      10-K - Protagenic Therapeutics, Inc.\new (0001022899) (Filer)

      3/31/25 2:06:25 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form PRE 14A filed by Protagenic Therapeutics Inc.

      PRE 14A - Protagenic Therapeutics, Inc.\new (0001022899) (Filer)

      2/27/25 9:45:01 AM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagenic Therapeutics Inc. filed SEC Form 8-K: Leadership Update

      8-K - Protagenic Therapeutics, Inc.\new (0001022899) (Filer)

      2/24/25 4:00:10 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    Protagenic Therapeutics Inc. Press Releases

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    • Protagenic Therapeutics Announces Closing of Private Placement for Aggregate Gross Proceeds of $1.275 Million

      NEW YORK, NY / ACCESSWIRE / November 5, 2024 / Protagenic Therapeutics, Inc. (NASDAQ:PTIX) ("Protagenic Therapeutics" or the "Company"), a leader in biopharmaceutical innovation, announced today that on November 4, 2024 it closed its previously announced private placement pursuant to a purchase agreement (the "Purchase Agreement") for the purchase and sale of an aggregate of 1,948,295 shares of common stock, series A common stock purchase warrants to purchase an aggregate of 1,948,295 shares of common stock, with an exercise price of $0.64 per share, which are exercisable on the trading day immediately following the Stockholder Approval Date (as defined in the Purchase Agreement) for a term

      11/5/24 8:12:00 AM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagenic Therapeutics Announces Pricing of Private Placement for Aggregate Gross Proceeds of $1.275 Million

      NEW YORK, NY / ACCESSWIRE / October 29, 2024 / Protagenic Therapeutics, Inc. (NASDAQ:PTIX) ("Protagenic Therapeutics" or the "Company"), a leader in biopharmaceutical innovation, announced today it has entered into a purchase agreement (the "Purchase Agreement") for the purchase and sale of an aggregate of 1,948,295 shares of common stock (or pre-funded warrants in lieu of shares of common stock), series A common stock purchase warrants to purchase an aggregate of 1,948,295 shares of common stock, with an exercise price of $0.64 per share, which are exercisable on the trading day immediately following the Stockholder Approval Date (as defined in the Purchase Agreement) for a term of eighteen

      10/29/24 9:27:00 AM ET
      $PTGX
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagenic Therapeutics' Stress-Regulating Peptide Demonstrates Exceptional Safety in Single Dose Portion of Phase I Trial, Paving the Way for Next Steps Toward Potential Breakthrough Treatments in Stress Related Neuropsychiatric Disorders

      No Clinically-Relevant Adverse Events Reported in Single Dose Portion, Multiple Dose Portion to CommenceInvestor Call Scheduled for today, Wednesday, May 22, at 10:00 am ET to Discuss Potential Impact on PTSD, Depression, Anxiety, Addiction, and ObesityNEW YORK, NY / ACCESSWIRE / May 22, 2024 / Protagenic Therapeutics, Inc. (NASDAQ:PTIX), a leader in biopharmaceutical innovation, today announced the complete safety data set from the single dose portion of its Phase 1 trial involving PT00114, its synthesized version of a natural stress-regulating brain peptide. The trial, which included 30 subjects across five cohorts receiving doses up to 1,000 micrograms, reported zero clinically-relevant a

      5/22/24 8:12:00 AM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagenic Therapeutics Completes Enrollment in Single Dose Portion of Phase 1 of Innovative Stress Disorder Trial

      NEW YORK, NY / ACCESSWIRE / May 1, 2024 / Protagenic Therapeutics, Inc. (NASDAQ:PTIX), a leader in biopharmaceutical innovation, today announced the completion of enrollment in the single dose portion of its Phase 1 trial involving PT00114, its synthetic stress-regulating peptide, for treating neuropsychiatric disorders. This marks a significant milestone with the enrollment of 30 subjects across five cohorts, receiving doses up to 1,000 micrograms.PT00114 has demonstrated outstanding tolerability with no adverse safety findings, building upon safety validations reported earlier this year. The trial progresses as PT00114 shows potential to transform treatment for anxiety, depression, PTSD, a

      5/1/24 8:38:00 AM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagenic Therapeutics' Innovative Peptide PT00114 to be Highlighted at Boston Summit

      Chief Operating Officer to Present Key Advances at Peptide Therapeutics Summit NEW YORK, NY / ACCESSWIRE / April 17, 2024 / Protagenic Therapeutics, Inc. (NASDAQ:PTIX), a pioneer in biopharmaceutical research, announced today that Dr. Andrew Slee, Chief Operating Officer, will present a talk on PT00114, the company's promising new drug candidate, at the Peptide Based Therapeutic Summit in Boston.Titled "Novel Blood-Brain Barrier Penetrating Peptide: Opening New Doors in Neuro-Psychiatric Treatment," Dr. Slee's talk will focus on the groundbreaking structure of PT00114, designed to efficiently cross the blood-brain barrier and unlock new potential in treating serious neuro-psychiatric conditi

      4/17/24 8:42:00 AM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagenic Therapeutics Reports Fourth Quarter and Full Year 2023 Results

      Transitioned from Pre-Clinical to Clinical Stage company in FY 2023Phase 1/2a trial, designed to assess both healthy volunteers and patients diagnosed with Treatment-Resistant Depression, PTSD or Generalized Anxiety Disorder, progressing through Phase 1 portionPlans to enroll final two out of five cohorts into the single dose portion of the Phase 1 trial within the next monthNEW YORK, NY / ACCESSWIRE / April 1, 2024 / Protagenic Therapeutics, Inc. (NASDAQ:PTIX), a leader in biopharmaceutical innovation, today provided a corporate update and reported financial results for the fourth quarter and full year 2023."In 2023, Protagenic Therapeutics achieved a significant milestone as we began enrol

      4/1/24 4:21:53 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagenic Therapeutics Successfully Concludes Third Cohort in Single Dose Portion of Phase 1 Trial for Stress-Related Neuropsychiatric Disorders

      Next clinical progress update expected in April 2024NEW YORK, NY / ACCESSWIRE / March 27, 2024 / Protagenic Therapeutics, Inc. (NASDAQ:PTIX), a leader in biopharmaceutical innovation, advances its mission to develop cutting-edge treatments for stress-related neuropsychiatric disorders. The company has reached another milestone by completing three out of five cohorts of healthy volunteers with PT00114, its synthetic version of the stress-regulating peptide TCAP, in a SAD Phase 1 clinical trial. Notably, PT00114 has shown excellent tolerability with no adverse safety findings during these ongoing Phase 1 studies. With promising preclinical efficacy in anxiety, depression, PTSD, and addiction m

      3/27/24 8:42:00 AM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagenic Therapeutics Schedules First Q4 and FY 2023 Earnings Call

      Call Scheduled for Monday, April 1st, 2024, at 4:30 pm ETNEW YORK, NY / ACCESSWIRE / March 25, 2024 / Protagenic Therapeutics, Inc. (NASDAQ:PTIX), a biopharmaceutical innovator, announced that the Company plans to hold its first investor earnings call to discuss the results contained in its FY 2023 Form 10K, which it plans to file that day, and its outlook for FY 2024.The Company plans to hold its earnings call, open to the public, at 4:30 pm ET on Monday, April 1st, to discuss the results of its Q4 and FY 2023, which it plans to publish in its Form 10K to be filed with the SEC that day. On the call, management also plans to discuss the company's outlook for FY 2024, including expectations f

      3/25/24 4:12:00 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagenic Therapeutics Announces Resolution of Nasdaq Deficiency Notice

      NEW YORK, NY / ACCESSWIRE / March 21, 2024 / Protagenic Therapeutics, Inc. (NASDAQ:PTIX), a biopharmaceutical innovator, regained compliance with Nasdaq Listing Rule 5550(a)(2) as the closing bid price of shares of PTIX has remained above $1.00 per share for ten consecutive trading days. This resolves the issue of potential delisting from Nasdaq by May 19, 2024 that the company had been facing.On Tuesday, November 21, 2023, the company received a deficiency letter from Nasdaq stating that it is not in compliance with the minimum bid price requirements set forth in Nasdaq Listing Rule 5550(a)(2) for continued listing on The Nasdaq Capital Market, because it had not maintained a minimum bid pr

      3/21/24 8:41:00 AM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagenic Therapeutics Achieves First Clinical Safety Milestone with its Novel Neuropeptide for the Potential Treatment of Stress-Related Disorders

      Company Anticipates Reporting Complete Phase I Single Dose Results in AprilNEW YORK, NY / ACCESSWIRE / February 13, 2024 / Protagenic Therapeutics, Inc. (NASDAQ:PTIX), a biopharmaceutical innovator, announced a step forward in its mission to address stress-related neuro-psychiatric disorders. The company has completed the first dose escalation step in the Phase I safety clinical trial for PT00114, its pioneering brain peptide compound. The compound has been extensively tested in models of anxiety, depression, PTSD and addiction before entering its present clinical trial.Key Highlights:Safety Validation: PT00114 has demonstrated safety at a low dose of 125 micrograms in the initial cohort of

      2/13/24 8:30:00 AM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    Protagenic Therapeutics Inc. Large Ownership Changes

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    • Amendment: SEC Form SC 13G/A filed by Protagenic Therapeutics Inc.

      SC 13G/A - Protagenic Therapeutics, Inc.\new (0001022899) (Subject)

      11/14/24 5:19:32 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G/A filed by Protagenic Therapeutics Inc. (Amendment)

      SC 13G/A - Protagenic Therapeutics, Inc.\new (0001022899) (Subject)

      2/14/24 2:29:52 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G/A filed by Protagenic Therapeutics Inc. (Amendment)

      SC 13G/A - Protagenic Therapeutics, Inc.\new (0001022899) (Subject)

      2/14/23 1:17:58 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G/A filed by Protagenic Therapeutics Inc. (Amendment)

      SC 13G/A - Protagenic Therapeutics, Inc.\new (0001022899) (Subject)

      2/4/22 4:29:55 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    Protagenic Therapeutics Inc. Insider Purchases

    Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

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    • Arrow Alexander K. bought $6,480 worth of PTIX Common Stock (8,000 units at $0.81), increasing direct ownership by 21% to 45,815 units (SEC Form 4)

      4 - Protagenic Therapeutics, Inc.\new (0001022899) (Issuer)

      10/13/23 12:48:45 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    Protagenic Therapeutics Inc. Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

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    • Maxim Group initiated coverage on Protagenic Therapeutics with a new price target

      Maxim Group initiated coverage of Protagenic Therapeutics with a rating of Buy and set a new price target of $4.00

      10/29/21 8:30:12 AM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    Protagenic Therapeutics Inc. Financials

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    Protagenic Therapeutics Inc. Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

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    • Protagenic Therapeutics Reports Fourth Quarter and Full Year 2023 Results

      Transitioned from Pre-Clinical to Clinical Stage company in FY 2023Phase 1/2a trial, designed to assess both healthy volunteers and patients diagnosed with Treatment-Resistant Depression, PTSD or Generalized Anxiety Disorder, progressing through Phase 1 portionPlans to enroll final two out of five cohorts into the single dose portion of the Phase 1 trial within the next monthNEW YORK, NY / ACCESSWIRE / April 1, 2024 / Protagenic Therapeutics, Inc. (NASDAQ:PTIX), a leader in biopharmaceutical innovation, today provided a corporate update and reported financial results for the fourth quarter and full year 2023."In 2023, Protagenic Therapeutics achieved a significant milestone as we began enrol

      4/1/24 4:21:53 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Protagenic Therapeutics Announces Date of Annual Shareholder Meeting

      NEW YORK, NY / ACCESSWIRE / October 13, 2023 / Protagenic Therapeutics, Inc. (NASDAQ:PTIX) a biopharmaceutical company focused on developing therapies to treat stress-related neurologic disorders, today announced its FY 2022 annual shareholder meeting will be held Wednesday, December 13, 2023, at 10:00 am EST, for shareholders of record as of this coming Monday, October 16th.Those who would like to attend the meeting virtually may do so by going to the website www.virtualshareholdermeeting.com/PTIX2023. After the regular business of the shareholder is concluded, Executive Chairman Garo Armen, PhD., is expected to provide comments on the progress of the Company's ongoing Phase I clinical tria

      10/13/23 9:00:00 AM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Wright Timothy R

      4 - Protagenic Therapeutics, Inc.\new (0001022899) (Issuer)

      4/1/24 9:41:26 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Barrage Khalil

      4 - Protagenic Therapeutics, Inc.\new (0001022899) (Issuer)

      3/29/24 9:29:19 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Stein Robert Benjamin

      4 - Protagenic Therapeutics, Inc.\new (0001022899) (Issuer)

      3/29/24 9:29:23 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Buell Jennifer

      4 - Protagenic Therapeutics, Inc.\new (0001022899) (Issuer)

      3/29/24 9:29:15 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Corvese Brian

      4 - Protagenic Therapeutics, Inc.\new (0001022899) (Issuer)

      3/29/24 9:29:10 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Armen Garo H

      4 - Protagenic Therapeutics, Inc.\new (0001022899) (Issuer)

      3/29/24 9:29:14 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Arrow Alexander K.

      4 - Protagenic Therapeutics, Inc.\new (0001022899) (Issuer)

      3/29/24 9:29:07 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Arrow Alexander K. bought $6,480 worth of PTIX Common Stock (8,000 units at $0.81), increasing direct ownership by 21% to 45,815 units (SEC Form 4)

      4 - Protagenic Therapeutics, Inc.\new (0001022899) (Issuer)

      10/13/23 12:48:45 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4: Arrow Alexander K. bought $22,090 worth of PTIX Common Stock (31,000 units at $0.71), increasing direct ownership by 26% to 151,260 units

      4 - Protagenic Therapeutics, Inc.\new (0001022899) (Issuer)

      5/18/22 5:11:21 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Arrow Alexander K.

      4 - Protagenic Therapeutics, Inc.\new (0001022899) (Issuer)

      6/3/21 6:13:18 PM ET
      $PTIX
      Biotechnology: Pharmaceutical Preparations
      Health Care