Homology Medicines, Inc., a genetic medicines company, focuses on transforming the lives of patients suffering from rare genetic diseases. Its proprietary platform is designed to utilize its human hematopoietic stem cell derived adeno-associated virus vectors (AAVHSCs) to deliver genetic medicines in vivo either through a gene therapy or nuclease-free gene editing across a range of genetic disorders. The company's various set of AAVHSCs allows company to target, through a single injection, a range of disease-relevant tissues, including the liver, central nervous system, peripheral nervous system, bone marrow, muscle, and eye. Its lead product candidate is HMI-102, which is in Phase I/II pheNIX clinical trial, a gene therapy for the treatment of phenylketonuria (PKU) in adults. The company also develops HMI-103 for the treatment of PKU in pediatric patients; HMI-202 to treat metachromatic leukodystrophy; and HMI-203 for the treatment of mucopolysaccharidosis type II. Homology Medicines, Inc. was incorporated in 2015 and is based in Bedford, Massachusetts.
IPO Year: 2018
Exchange: NASDAQ
Website: homologymedicines.com
| Date | Price Target | Rating | Analyst |
|---|---|---|---|
| 7/28/2023 | $9.00 → $1.50 | Outperform → Neutral | Robert W. Baird |
| 2/28/2022 | $30.00 → $20.00 | Buy | HC Wainwright & Co. |
| 2/22/2022 | $25.00 → $9.00 | Buy | B of A Securities |
| 2/22/2022 | $35.00 → $29.00 | Neutral | BTIG Research |
| 2/22/2022 | Outperform → Sector Perform | RBC Capital Mkts | |
| 2/22/2022 | $25.00 → $15.00 | Buy | Chardan Capital |
| 2/22/2022 | $35.00 → $29.00 | Buy | BTIG |
| 2/22/2022 | $30.00 → $4.00 | Outperform → Sector Perform | RBC Capital |
| 2/22/2022 | Outperform → Perform | Oppenheimer | |
| 11/16/2021 | $30.00 → $25.00 | Buy | Chardan Capital |
- ASGCT President and Entrepreneur Takes Leadership Role on SAB as Company Expects to Have Three Clinical Programs in 2021 - BEDFORD, Mass., Aug. 05, 2021 (GLOBE NEWSWIRE) -- Homology Medicines, Inc. (NASDAQ:FIXX), a clinical-stage genetic medicines company, announced today the appointment of gene therapy expert Beverly Davidson, Ph.D., as Chair of the Company's Scientific Advisory Board, on which she has served since 2018. Dr. Davidson is the Director of the Raymond G. Perelman Center for Cellular and Molecular Therapeutics, the Chief Scientific Strategy Officer, and holds the Arthur V. Meigs Chair in Pediatrics at the Children's Hospital of Philadelphia. She was also recently named Pr
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Oxford Biomedica and Homology Medicines to establish Oxford Biomedica Solutions LLC, a new U.S.-based AAV Manufacturing and Innovation Business Homology Medicines to receive $130 million from Oxford Biomedica to continue to advance its three clinical programs and genetic medicines platform Oxford Biomedica to invest $50 million to fund the growth of Oxford Biomedica Solutions LLC and will own 80%, with Homology Medicines to own 20%; Homology Medicines to secure preferred key customer status Dr. Roch Doliveux to become Interim CEO of Oxford Biomedica and John Dawson to retire as CEO and remain a Board Director of Oxford Biomedica Oxford Biomedica and Homology Medicines to host webcasts t
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BEDFORD, Mass., March 02, 2023 (GLOBE NEWSWIRE) -- Homology Medicines, Inc. (NASDAQ:FIXX), a genetic medicines company, announced today that Albert Seymour, Ph.D., President and Chief Executive Officer, will participate in the "Gene Editing Corporate Panel" during the 43rd Annual Cowen Healthcare Conference on Wednesday, March 8, 2023 at 10:30 a.m. ET. The live webcast presentation will be accessible on Homology's website in the Investors section, and the webcast replay will be available on the website for 90 days following the presentation. About Homology Medicines, Inc.Homology Medicines, Inc. is a clinical-stage genetic medicines company dedicated to transforming the lives of patients
BEDFORD, Mass., Oct. 06, 2022 (GLOBE NEWSWIRE) -- Homology Medicines, Inc. (NASDAQ:FIXX), a clinical-stage genetic medicines company, announced today participation at the following conferences. Cell & Gene Meeting on the Mesa Corporate presentation given by Albert Seymour, Ph.D., President and Chief Executive Officer of Homology, on October 11 at 3:15 p.m. PT"Gene Editing Accelerates: The First Generation Nears Approval While New Approaches Progress Through the Clinic" panel featuring Dr. Seymour on October 11 at 4:00 p.m. PT"New Business Models for Manufacturing Investment" panel featuring Arthur Tzianabos, Ph.D., Chairman of the Board of Homology, on October 12 at 3:15 p.m. PT
SAN FRANCISCO and BOSTON, Sept. 27, 2022 (GLOBE NEWSWIRE) -- 5AM Ventures, a bicoastal venture capital firm, continues to attract preeminent talent as it celebrates 20 years of investing in early-stage life science companies. The firm is currently deploying capital in breakthrough science opportunities throughout North America and Europe from its $450 million 5AM Ventures VII fund and its $300 million 5AM Opportunities II fund, which has an additional mandate to invest in public market opportunities. 5AM is pleased to announce the addition of two Venture Partners to the firm's investment team, and a Venture Advisor to the advisory team. Dr. Arthur Tzianabos has joined 5AM as a Venture Pa
BEDFORD, Mass., June 29, 2022 (GLOBE NEWSWIRE) -- Homology Medicines, Inc. (NASDAQ:FIXX), a genetic medicines company, announced today participation and presentations at the following conferences: FASEB's The Genome Engineering Conference: Cutting-Edge Research and Applications on June 29, 2022 at 5:30 p.m. WET/12:30 p.m. ET in Lisbon, Portugal Homology will deliver an oral presentation titled, "Molecular Characterization of In Vivo Editing in Human Hepatocytes and a PKU Mouse Model using rAAVHSCs," which confirms the precision of homologous recombination-based integration of HMI-103 nuclease-free gene editing candidate for phenylketonuria (PKU) using genome-wide assays. 2022 NPKUA Confe
- Multiple Presentations Feature HMI-103 Phase 1 Investigational Therapy for PKU, Including Genome-Wide Integration Assays to Confirm No Off-Target Editing - - New Data from GTx-mAb Program Support Potential to Target Many Complement-Related Disorders - - Presentations Feature the Discovery and Characterization of a Non-Liver-Tropic Capsid and Other Distinct Properties of Homology's Family of 15 Naturally Derived AAVHSCs - - Symposium to be Held on May 18, 2022 at 7:30 a.m. ET - BEDFORD, Mass., May 02, 2022 (GLOBE NEWSWIRE) -- Homology Medicines, Inc. (NASDAQ:FIXX), a genetic medicines company, announced today that the first presentation detailing the optimization and mechanism of act
BEDFORD, Mass., April 21, 2022 (GLOBE NEWSWIRE) -- Homology Medicines, Inc. (NASDAQ:FIXX), a genetic medicines company, announced today that Albert Seymour, Ph.D., Chief Scientific Officer, has been promoted to President of Homology. In addition to his role as CSO, Dr. Seymour will assume broader responsibilities for additional functional areas, including human resources, clinical development and operations, and commercial strategy. "Albert has fostered a culture of scientific innovation and execution that brought our first gene therapy candidate to the clinic within three years from inception, and this was followed closely by two additional trial initiations, including our first nuclease
- Formed New AAV Manufacturing and Innovation Business with Oxford Biomedica to Leverage Homology's Process Development and Manufacturing Capabilities - - Received $130 Million Non-Dilutive Capital that Significantly Extends Cash Runway - - Launched pheEDIT Gene Editing Trial for PKU and juMPStart Gene Therapy Trial for Hunter Syndrome; Program Updates Expected by Year-End - - Company Updates Guidance on pheNIX Gene Therapy Trial for PKU - BEDFORD, Mass., March 23, 2022 (GLOBE NEWSWIRE) -- Homology Medicines, Inc. (NASDAQ:FIXX), a genetic medicines company, announced today financial results for the fourth quarter and full year ended December 31, 2021, and highlighted recent accomplishm
Unique platform offering capabilities from vector design and process development through to clinical trials is now available to new customers Oxford, UK – 11 March 2022: Oxford Biomedica plc (LSE:OXB) ("Oxford Biomedica" or the "Company"), a leading gene and cell therapy group, is pleased to announce that it has completed its deal with Homology Medicines Inc. (NASDAQ:FIXX) ("Homology"), a genetic medicines company, to establish Oxford Biomedica Solutions LLC, a new US-based full scope, Adeno-Associated Virus (AAV) manufacturing and innovation business. The new Oxford Biomedica Solutions business is fully operational and offers a proprietary ‘plug and play' platform that is capable of achie
BEDFORD, Mass., March 10, 2022 (GLOBE NEWSWIRE) -- Homology Medicines, Inc. (NASDAQ:FIXX), a genetic medicines company, announced today the successful closing of the deal with Oxford Biomedica plc (LSE: OXB) to establish an Adeno-Associated Virus (AAV) Manufacturing and Innovation Business. The new company, Oxford Biomedica Solutions LLC, incorporates Homology's technical and manufacturing operations, team and GMP facility with OXB's extensive know-how in viral vector manufacturing. Homology will maintain access to the capabilities that the Company built over the past four years, as well as share in potential benefits derived from future innovations as a 20% owner and preferred customer of
BEDFORD, Mass., March 03, 2022 (GLOBE NEWSWIRE) -- Homology Medicines, Inc. (NASDAQ:FIXX), a genetic medicines company, announced today participation at the following virtual investor conferences: Cowen 42nd Annual Health Care Conference: Corporate Panel Discussion – Gene Editing: March 8 at 12:50 p.m. ET Oppenheimer 32nd Annual Healthcare Conference: Fireside Chat: March 16 at 1:20 p.m. ET H.C. Wainwright Gene Therapy and Gene Editing Conference: Available on-demand March 30 at 7:00 a.m. ET The webcast presentations from the investor conferences will be accessible on Homology's website in the Investors section, and the webcast replays will be available on the website for 90 days fo
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Robert W. Baird downgraded Homology Medicines from Outperform to Neutral and set a new price target of $1.50 from $9.00 previously
HC Wainwright & Co. reiterated coverage of Homology Medicines with a rating of Buy and set a new price target of $20.00 from $30.00 previously
B of A Securities reiterated coverage of Homology Medicines with a rating of Buy and set a new price target of $9.00 from $25.00 previously
BTIG Research reiterated coverage of Homology Medicines with a rating of Neutral and set a new price target of $29.00 from $35.00 previously
RBC Capital Mkts downgraded Homology Medicines from Outperform to Sector Perform
Chardan Capital reiterated coverage of Homology Medicines with a rating of Buy and set a new price target of $15.00 from $25.00 previously
BTIG reiterated coverage of Homology Medicines with a rating of Buy and set a new price target of $29.00 from $35.00 previously
RBC Capital downgraded Homology Medicines from Outperform to Sector Perform and set a new price target of $4.00 from $30.00 previously
Oppenheimer downgraded Homology Medicines from Outperform to Perform
Chardan Capital reiterated coverage of Homology Medicines with a rating of Buy and set a new price target of $25.00 from $30.00 previously