4 - PALISADE BIO, INC. (0001357459) (Issuer)

4 - PALISADE BIO, INC. (0001357459) (Issuer)

4 - PALISADE BIO, INC. (0001357459) (Issuer)

4 - PALISADE BIO, INC. (0001357459) (Issuer)

4 - PALISADE BIO, INC. (0001357459) (Issuer)

4 - PALISADE BIO, INC. (0001357459) (Issuer)

4 - PALISADE BIO, INC. (0001357459) (Issuer)

3 - PALISADE BIO, INC. (0001357459) (Issuer)

3 - PALISADE BIO, INC. (0001357459) (Issuer)

3 - PALISADE BIO, INC. (0001357459) (Issuer)

8-K/A - PALISADE BIO, INC. (0001357459) (Filer)

8-K - PALISADE BIO, INC. (0001357459) (Filer)

8-K - PALISADE BIO, INC. (0001357459) (Filer)

8-K/A - Seneca Biopharma, Inc. (0001357459) (Filer)

425 - Seneca Biopharma, Inc. (0001357459) (Subject)

425 - Seneca Biopharma, Inc. (0001357459) (Subject)

425 - Seneca Biopharma, Inc. (0001357459) (Subject)

8-K/A - Seneca Biopharma, Inc. (0001357459) (Filer)

425 - Seneca Biopharma, Inc. (0001357459) (Subject)

425 - Seneca Biopharma, Inc. (0001357459) (Subject)

GERMANTOWN, Md., April 26, 2021 /PRNewswire/ -- Seneca Biopharma, Inc. (NASDAQ:SNCA) ("Seneca" or the "Company"), disclosed on April 23, 2021, the passing of the final proposal required for approval of the proposed merger between Seneca and Leading Biosciences, Inc. ("LBS").  The Merger is expected to close on or about April 27, 2021 and the new combined company, Palisades Bio, is expected to begin trading on the Nasdaq Capital Market on or about April 28, 2021 under the ticker "PALI". Seneca and LBS will announce the final exchange ratio prior to the common stock commencing trading on or about Wednesday, April 28, 2021. About Leading BioSciences, Inc.LBS is developing novel therapeutics des

CARLSBAD, Calif., April 20, 2021 (GLOBE NEWSWIRE) -- Leading BioSciences, Inc. ("LBS" or "the Company"), a privately held company that recently entered into a definitive agreement for a reverse merger with Seneca Biopharma, Inc. (NASDAQ:SNCA), subject to certain conditions to be completed, to form Palisade Bio, Inc., announced data from an open label GI surgery study with lead asset LB1148 that provided an early indication of efficacy signal in reducing post-surgical adhesions following elective bowel resection. No abdominal adhesions were observed at the time of a follow-up surgery in two patients treated with LB1148. Although these are early data in a limited number of patients, the dat

GERMANTOWN, Md., April 12, 2021 /PRNewswire/ -- Seneca Biopharma, Inc. (Nasdaq: SNCA) ("Seneca" or the "Company"), announced the preliminary voting results of its Special Meeting of Stockholders on April 9, 2021. At the Special Meeting, Seneca asked stockholders to approve six proposals related to its proposed merger transaction with Leading BioSciences, Inc. ("LBS"), a biopharma company advancing therapies for acute and chronic gastrointestinal complications. All proposals, with the exception of proposal #1 for a reverse stock split (the "Reverse Split Proposal"), were approved by Seneca stockholders. In order to solicit additional votes for the Reverse Split Proposal, the Special Meeting w

GERMANTOWN, Md., March 24, 2021 /PRNewswire/ -- Seneca Biopharma, Inc. (Nasdaq: SNCA) (the "Company") today announced that the Company adjourned its special meeting of stockholders scheduled for Wednesday, March 24, 2021 at 11:00 a.m. (Eastern Time), until Friday, April 9, 2021 at 11:00 a.m. (Eastern Time), to be held virtually at www.virtualshareholdermeeting.com/SNCA2021SM. The Meeting is being adjourned to solicit additional votes. On December 17, 2020, the Company announced the proposed merger between Seneca and Leading BioSciences, Inc., which will result in a combined company to be named Palisade Bio, Inc. On February 12, 2021, the Company mailed its shareholders copies of the combined

GERMANTOWN, Md., March 22, 2021 /PRNewswire/ -- Seneca Biopharma, Inc. (Nasdaq: SNCA), a biopharmaceutical company focused on developing novel treatments for diseases of high unmet medical need, today reported its financial results for the year ended December 31, 2020. Business Highlights for 2020 to date. During 2020, the Company achieved the following business milestones: Entered into a definitive Merger Agreement with Leading BioSciences, Inc. (LBS), a privately held company focused on developing novel therapeutics to improve human health through therapeutic protection of the gastrointestinal mucosal barrier. Completed offerings resulting in net proceeds of over $14.7 million. Continu

GERMANTOWN, Md., March 17, 2021 /PRNewswire/ -- Seneca Biopharma, Inc. (Nasdaq: SNCA), today announced that leading independent proxy advisory firm Institutional Shareholder Services, Inc. ("ISS") has recommended that Seneca stockholders vote in support of the proposed merger with Leading BioSciences, Inc. ("LBS") and vote "FOR" the proposals for the reverse stock split and issuance of shares in connection with the merger, to be considered and voted on at Seneca's March 24, 2021 special meeting of stockholders. "We are very pleased that ISS supports the Seneca board's recommendation that stockholders vote "FOR" the proposals in support of the merger with LBS," said Ken Carter, Seneca's Chai

CARLSBAD, Calif., March 02, 2021 (GLOBE NEWSWIRE) -- Leading BioSciences, Inc. (“LBS”), a privately held company that recently entered into a definitive agreement for a reverse merger with Seneca Biopharma, Inc. (Nasdaq: SNCA) to form Palisade Bio, Inc., today announced that the Company will present at the upcoming H.C. Wainwright Global Life Sciences Conference, which is being held virtually from March 9-10, 2021. The Company’s presentation will be available on-demand through the H.C. Wainwright conference portal, starting at 7 a.m. EST on Tuesday, March 9, 2021. A webcast will also be available through the “News” section of the Company’s website for 90 days after the conference event.

GERMANTOWN, Md., Jan. 25, 2021 /PRNewswire/ -- Seneca Biopharma, Inc, (NASDAQ:SNCA), a biopharmaceutical company focused on developing novel treatments for diseases of high unmet medical need, today announced that it received notice from The NASDAQ Stock Market LLC (NASDAQ) on January 22, 2021 indicating that the company has regained compliance with the minimum bid price requirement under NASDAQ Listing Rule 5550(a)(2) for continued listing on The NASDAQ Capital Market. On March 30, 2020, Seneca received a written notice from the NASDAQ Stock Market LLC that it was not in compliance with NASDAQ Listing Rule 5550(a)(2) as a result of the minimum bid price of its common stock being below $

GERMANTOWN, Md., Jan. 20, 2021 /PRNewswire/ -- Seneca Biopharma, Inc. (Nasdaq: SNCA), a biopharmaceutical company focused on developing novel treatments for diseases of high unmet medical need, today announced preliminary, top-line results of the Company's placebo controlled Phase 2 stroke study (non-GCP) that was conducted in Beijing, China. The trial was designed to evaluate the relative safety of the Company's human neural stem cell therapy, NSI-566, in patients with stable deficits in motor function resulting from ischemic stroke. Patients were eligible for the trial if they had documented history of ischemic stroke at least four months, but no more than 24 months, before surgery. Th

CARLSBAD, Calif., Jan. 13, 2021 (GLOBE NEWSWIRE) -- Leading BioSciences, Inc. (“LBS”), a privately held company that recently entered into a definitive agreement for a reverse merger with Seneca Biopharma, Inc. (Nasdaq: SNCA) to form Palisade Bio, Inc., announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track Designation to LB1148 for the treatment of postoperative gastrointestinal (GI) dysfunction associated with pediatric heart surgery.   “Even with high success rates of neonatal heart surgery, longer-term outcomes in pediatric patients are, to a great extent, dependent upon the speed of postoperative recovery of GI function,” said Dr. Michael Dawson, Chief Medi