• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • AI SuperconnectorNEW
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • AI SuperconnectorNEW
  • Settings
  • RSS Feeds
PublishGo to AppAI Superconnector
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlertsPublish with Us
    Company
    AboutQuantisnow PlusContactJobsAI superconnector for talent & startupsNEW
    Legal
    Terms of usePrivacy policyCookie policy

    Amendment: SEC Form SCHEDULE 13G/A filed by CASI Pharmaceuticals Inc.

    8/12/25 4:05:16 PM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $CASI alert in real time by email



    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549


    SCHEDULE 13G


    UNDER THE SECURITIES EXCHANGE ACT OF 1934
    (Amendment No. 1)


    CASI Pharmaceuticals, Inc.

    (Name of Issuer)


    Ordinary Shares, par value $0.0001

    (Title of Class of Securities)


    G1933S101

    (CUSIP Number)


    06/30/2025

    (Date of Event Which Requires Filing of this Statement)


    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
    Checkbox not checked   Rule 13d-1(b)
    Checkbox checked   Rule 13d-1(c)
    Checkbox not checked   Rule 13d-1(d)






    SCHEDULE 13G

    CUSIP No.
    G1933S101


    1Names of Reporting Persons

    Foresite Capital Fund VI, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    787,121.00
    6Shared Voting Power

    0.00
    7Sole Dispositive Power

    787,121.00
    8Shared Dispositive Power

    0.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    787,121.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    5.1 %
    12Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:  Note to Row 5: 787,121 shares, except that Foresite Capital Management VI, LLC ("FCM VI"), the general partner of Foresite Capital Fund VI, L.P. ("FCF VI"), may be deemed to have sole power to vote these shares, and James Tananbaum ("Tananbaum"), the managing member of FCM VI, may be deemed to have sole power to vote these shares. Note to row 6: See response to row 5. Note to Row 7: 787,121 shares, except that FCM VI, the general partner of FCF VI, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM VI, may be deemed to have sole power to dispose of these shares. Note to row 8: See response to row 7. Note to Row 11: This percentage is calculated based upon 15,492,581 Ordinary Shares outstanding of CASI Pharmaceuticals, Inc. (the "Issuer") as of December 31, 2024, as set forth in the Issuer's Form 20-F filed with the Securities and Exchange Commission on March 31, 2025.


    SCHEDULE 13G

    CUSIP No.
    G1933S101


    1Names of Reporting Persons

    Foresite Capital Management VI, LLC
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    787,121.00
    6Shared Voting Power

    0.00
    7Sole Dispositive Power

    787,121.00
    8Shared Dispositive Power

    0.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    787,121.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    5.1 %
    12Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:  Note to Row 5: 787,121 shares, all of which are directly owned by FCF VI. FCM VI, the general partner of FCF VI, may be deemed to have sole power to vote these shares, and Tananbaum, the managing member of FCM VI, may be deemed to have sole power to vote these shares. Note to row 6: See response to row 5. Note to Row 7: 787,121 shares, all of which are directly owned by FCF VI. FCM VI, the general partner of FCF VI, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM VI, may be deemed to have sole power to dispose of these shares. Note to row 8: See response to row 7. Note to Row 11: This percentage is calculated based upon 15,492,581 Ordinary Shares outstanding of the Issuer as of December 31, 2024, as set forth in the Issuer's Form 20-F filed with the Securities and Exchange Commission on March 31, 2025.


    SCHEDULE 13G

    CUSIP No.
    G1933S101


    1Names of Reporting Persons

    James Tananbaum
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    UNITED STATES
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    787,121.00
    6Shared Voting Power

    0.00
    7Sole Dispositive Power

    787,121.00
    8Shared Dispositive Power

    0.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    787,121.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    5.1 %
    12Type of Reporting Person (See Instructions)

    IN

    Comment for Type of Reporting Person:  Note to Row 5: 787,121 shares, all of which are directly owned by FCF VI. Tananbaum is the managing member of FCM VI, which is the general partner of FCF VI. Tananbaum may be deemed to have sole power to vote these shares. Note to row 6: See response to row 5. Note to Row 7: 787,121 shares, all of which are directly owned by FCF VI. Tananbaum is the managing member of FCM VI, which is the general partner of FCF VI. Tananbaum may be deemed to have sole power to dispose of these shares. Note to row 8: See response to row 7. Note to Row 11: This percentage is calculated based upon 15,492,581 Ordinary Shares outstanding of the Issuer as of December 31, 2024, as set forth in the Issuer's Form 20-F filed with the Securities and Exchange Commission on March 31, 2025.


    SCHEDULE 13G

    Item 1. 
    (a)Name of issuer:

    CASI Pharmaceuticals, Inc.
    (b)Address of issuer's principal executive offices:

    1701-1702, China Central Office Tower 1 No. 81 Jianguo Road, Chaoyang District Beijing, F4, 100025
    Item 2. 
    (a)Name of person filing:

    This Schedule is filed by Foresite Capital Fund VI, L.P., a Delaware limited partnership ("FCF VI"), Foresite Capital Management VI, LLC, a Delaware limited liability company ("FCM VI") and James Tananbaum. The foregoing entities and individuals are collectively referred to as the "Reporting Persons."
    (b)Address or principal business office or, if none, residence:

    c/o Foresite Capital Management 900 Larkspur Landing Circle, Suite 150Larkspur, CA 94939 See Row 4 of cover page for each Reporting Person.
    (c)Citizenship:

    See Row 4 of cover page for each Reporting Person.
    (d)Title of class of securities:

    Ordinary Shares, par value $0.0001
    (e)CUSIP No.:

    G1933S101
    Item 3.If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
    (a)Checkbox not checked   Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
    (b)Checkbox not checked   Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
    (c)Checkbox not checked   Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
    (d)Checkbox not checked   Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
    (e)Checkbox not checked   An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
    (f)Checkbox not checked   An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
    (g)Checkbox not checked   A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
    (h)Checkbox not checked   A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
    (i)Checkbox not checked   A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
    (j)Checkbox not checked   A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
           please specify the type of institution:
    (k)Checkbox not checked   Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
     
    Item 4.Ownership
    (a)Amount beneficially owned:

    See Row 9 of cover page for each Reporting Person.
    (b)Percent of class:

    See Row 11 of cover page for each Reporting Person.
    (c)Number of shares as to which the person has:
     (i) Sole power to vote or to direct the vote:

    See Row 5 of cover page for each Reporting Person.

     (ii) Shared power to vote or to direct the vote:

    See Row 6 of cover page for each Reporting Person.

     (iii) Sole power to dispose or to direct the disposition of:

    See Row 7 of cover page for each Reporting Person.

     (iv) Shared power to dispose or to direct the disposition of:

    See Row 8 of cover page for each Reporting Person.

    Item 5.Ownership of 5 Percent or Less of a Class.
     
    Item 6.Ownership of more than 5 Percent on Behalf of Another Person.
     
    If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required.


    Under certain circumstances set forth in the limited partnership agreement of FCF VI and the limited liability company agreement of FCM VI, the partners or members, as the case may be, of each of such entities may be deemed to have the right to receive dividends from, or the proceeds from the sale of, shares of the Issuer directly or indirectly owned by each such entity of which they are a partner or member.
    Item 7.Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
     
    Not Applicable
    Item 8.Identification and Classification of Members of the Group.
     
    Not Applicable
    Item 9.Notice of Dissolution of Group.
     
    Not Applicable

    Item 10.Certifications:
     
    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

        SIGNATURE 
     
    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     
    Foresite Capital Fund VI, L.P.
     
    Signature:/s/ James Tananbaum
    Name/Title:James Tananbaum, Managing Member of the General Partner
    Date:08/12/2025
     
    Foresite Capital Management VI, LLC
     
    Signature:/s/ James Tananbaum
    Name/Title:James Tananbaum, Managing Member
    Date:08/12/2025
     
    James Tananbaum
     
    Signature:/s/ James Tananbaum
    Name/Title:James Tananbaum
    Date:08/12/2025
    Exhibit Information

    Exhibit A Agreement of Joint Filing The undersigned hereby agree that a single Schedule 13G (or any amendment thereto) relating to the Ordinary Shares of the Issuer shall be filed on behalf of each of the undersigned. Note that a copy of the applicable Agreement of Joint Filing is already on file with the appropriate agencies.

    Get the next $CASI alert in real time by email

    Crush Q3 2025 with the Best AI Superconnector

    Stay ahead of the competition with Standout.work - your AI-powered talent-to-startup matching platform.

    AI-Powered Inbox
    Context-aware email replies
    Strategic Decision Support
    Get Started with Standout.work

    Recent Analyst Ratings for
    $CASI

    DatePrice TargetRatingAnalyst
    More analyst ratings

    $CASI
    Press Releases

    Fastest customizable press release news feed in the world

    View All

    CASI Announces First Patient Dosed in Phase 1/2 Clinical Trial of CID-103 in Immune Thrombocytopenia

    BEIJING, CHINA / ACCESSWIRE / January 6, 2025 / CASI Pharmaceuticals, Inc. (NASDAQ:CASI), a biopharmaceutical company specializing in the development and commercialization of innovative therapeutic and pharmaceutical products announced that the first patient has been dosed in the Phase 1/2 trial to evaluate the safety and tolerability of CID-103 in adult patients with chronic Immune Thrombocytopenia (ITP) in China."Dosing the first patient in our phase 1/2 study marks a significant milestone for both CID-103 program and chronic ITP patients who have limited treatment options," said Dr. Wei-Wu He, Chairman and CEO of CASI, "The rapid execution underscores our commitment to accelerating clinic

    1/6/25 8:00:00 AM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    CASI Pharmaceuticals Announces Third Quarter 2024 Business and Financial Results

    BEIJING, CHINA / ACCESSWIRE / November 15, 2024 / CASI Pharmaceuticals, Inc. (NASDAQ:CASI) ("CASI" or the "Company"), a Cayman incorporated biopharmaceutical company specializing in the development and commercialization of innovative therapeutics and pharmaceutical products, today reported business updates and financial results for the three months ended September 30, 2024.Dr. Wei-Wu He, Chairman and CEO of CASI, said "The third quarter of 2024 marks a period of substantial progress for CASI as we continue to refine our company's strategic focus on the development for organ transplant rejection and autoimmune diseases. We just announced the Center for Drug Evaluation (CDE) of China's Nationa

    11/15/24 8:00:00 AM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    CASI Pharmaceuticals Receives CTA Approval From China's NMPA for CID-103 in Immune Thrombocytopenia

    BEIJING, CHINA / ACCESSWIRE / October 24, 2024 / CASI Pharmaceuticals, Inc. (NASDAQ:CASI), a biopharmaceutical company specializing in the development and commercialization of innovative therapeutic and pharmaceutical products announced that the Center for Drug Evaluation (CDE) of China's National Medical Products Administration (NMPA) has approved the Company's Clinical Trial Application (CTA) to proceed with a phase 1/2 study of CID-103 in adults patients with chronic Immune Thrombocytopenia (ITP) in China. This China study is part of the global study that was approved by the US FDA in May 2024.CID-103 is a fully human IgG1 anti-CD38 monoclonal antibody recognizing a unique epitope that ha

    10/24/24 8:00:00 AM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $CASI
    SEC Filings

    View All

    Amendment: SEC Form SCHEDULE 13G/A filed by CASI Pharmaceuticals Inc.

    SCHEDULE 13G/A - CASI Pharmaceuticals, Inc. (0001962738) (Subject)

    8/12/25 4:05:16 PM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 6-K filed by CASI Pharmaceuticals Inc.

    6-K - CASI Pharmaceuticals, Inc. (0001962738) (Filer)

    8/4/25 9:10:21 AM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Amendment: SEC Form SCHEDULE 13G/A filed by CASI Pharmaceuticals Inc.

    SCHEDULE 13G/A - CASI Pharmaceuticals, Inc. (0001962738) (Subject)

    7/23/25 9:39:43 AM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $CASI
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    View All

    SEC Form 4 filed by Zukiwski Alexander A

    4 - CASI Pharmaceuticals, Inc. (0000895051) (Issuer)

    9/9/22 4:01:37 PM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4: Huang James bought $229,662 worth of shares (55,573 units at $4.13)

    4 - CASI Pharmaceuticals, Inc. (0000895051) (Issuer)

    9/8/22 6:51:39 PM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4: Huang James bought $139,036 worth of shares (37,196 units at $3.74)

    4 - CASI Pharmaceuticals, Inc. (0000895051) (Issuer)

    9/2/22 7:35:18 PM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $CASI
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    View All

    BTIG Research initiated coverage on CASI Pharma with a new price target

    BTIG Research initiated coverage of CASI Pharma with a rating of Buy and set a new price target of $4.00

    5/18/21 6:41:48 AM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    HC Wainwright & Co. reiterated coverage on CASI Pharmaceuticals with a new price target

    HC Wainwright & Co. reiterated coverage of CASI Pharmaceuticals with a rating of Buy and set a new price target of $4.00 from $3.50 previously

    5/14/21 6:40:01 AM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Mizuho initiated coverage on CASI Pharmaceuticals with a new price target

    Mizuho initiated coverage of CASI Pharmaceuticals with a rating of Buy and set a new price target of $3.80

    4/26/21 7:19:24 AM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $CASI
    Financials

    Live finance-specific insights

    View All

    Ligand Reports Second Quarter 2024 Financial Results

    Conference call at 4:30 p.m. Eastern Time today Ligand Pharmaceuticals Incorporated (NASDAQ:LGND) today reported financial results for the three and six months ended June 30, 2024, and provided an operating forecast and business update. Ligand management will host a conference call and webcast today at 4:30 p.m. Eastern Time to discuss this announcement and answer questions. "We had a strong quarter and are on track to meet the long-term growth objectives we outlined in December," said Todd Davis, CEO of Ligand. "We added four new commercial-stage programs in the first half of this year, including QARZIBA®, an orphan oncology product we acquired following the APEIRON Biologics transacti

    8/6/24 4:01:00 PM ET
    $AGEN
    $AMGN
    $CASI
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Biotechnology: Pharmaceutical Preparations

    Ligand Reports First Quarter 2024 Financial Results

    Conference Call Begins at 4:30 p.m. Eastern Time Today Ligand Pharmaceuticals Incorporated (NASDAQ:LGND) today reported financial results for the three months ended March 31, 2024, and provided an operating forecast and business updates. Ligand management will host a conference call today beginning at 4:30 p.m. Eastern Time to discuss this announcement and answer questions. "We are pleased to report another quarter of strong financial results driven by the performance of our commercial royalty portfolio. Simultaneously, we continue to build our portfolio of development stage royalty assets to deliver future growth," said Todd Davis, CEO of Ligand. "We continue to originate a robust pipe

    5/7/24 4:00:00 PM ET
    $AMGN
    $CASI
    $JAZZ
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Biotechnology: Pharmaceutical Preparations

    CASI Pharmaceuticals Acquires Global Intellectual Property Rights to Cleave Therapeutics' VCP/P97 Inhibitor CB-5339

    BEIJING, July 20, 2023 /PRNewswire/ -- CASI Pharmaceuticals, Inc. (NASDAQ:CASI), a biopharmaceutical company focused on developing and commercializing innovative therapeutics and pharmaceutical products, today announced the execution of the Assignment Agreement (the "Agreement") with Cleave Therapeutics, Inc. ("Cleave"), pursuant to which CASI obtained all rights and global intellectual property rights related to CB-5339, a novel VCP/p97 inhibitor, as well as all remaining CB-5339 drug substance and drug product. Additionally, CASI will assume responsibility of the United States ("US") CB-5339 Investigational New Drug ("IND") application.

    7/20/23 8:00:00 AM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $CASI
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    View All

    Amendment: SEC Form SC 13G/A filed by CASI Pharmaceuticals Inc.

    SC 13G/A - CASI Pharmaceuticals, Inc. (0001962738) (Subject)

    10/29/24 4:05:28 PM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Amendment: SEC Form SC 13D/A filed by CASI Pharmaceuticals Inc.

    SC 13D/A - CASI Pharmaceuticals, Inc. (0001962738) (Subject)

    8/12/24 8:27:51 AM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form SC 13G filed by CASI Pharmaceuticals Inc.

    SC 13G - CASI Pharmaceuticals, Inc. (0001962738) (Subject)

    7/25/24 8:48:03 PM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $CASI
    Leadership Updates

    Live Leadership Updates

    View All

    CASI Pharmaceuticals announces appointment of Daniel Lang, MD as CFO and SVP

    BEIJING, July 8, 2024 /PRNewswire/ -- CASI Pharmaceuticals, Inc. (NASDAQ:CASI), a Cayman incorporated biopharmaceutical company focused on developing and commercializing innovative therapeutics and pharmaceutical products today announces appointment of Daniel Lang, MD as Chief Financial Officer and Senior Vice President, effective July 8th, 2024. Dr. Lang has more than 30 years of experience as a physician scientist, investor, and biotech executive. He is a cardiologist by training from UCSF, followed by 20 years of investment experience as a portfolio manager at Farallon Capi

    7/8/24 7:30:00 AM ET
    $CASI
    Biotechnology: Pharmaceutical Preparations
    Health Care