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    Director Perceptive Advisors Llc was granted 555,555 units of Ordinary Shares (SEC Form 4)

    4/23/26 8:59:00 PM ET
    $MGTX
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $MGTX alert in real time by email
    SEC FORM 4SEC Form 4
    FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549

    STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

    Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
    or Section 30(h) of the Investment Company Act of 1940
    OMB APPROVAL
    OMB Number:3235-0287
    Estimated average burden
    hours per response:0.5
      
    Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
      
    Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
    1. Name and Address of Reporting Person*
    PERCEPTIVE ADVISORS LLC

    (Last)(First)(Middle)
    51 ASTOR PLACE, 10TH FLOOR

    (Street)
    NEW YORK NEW YORK 10003

    (City)(State)(Zip)

    UNITED STATES

    (Country)
    2. Issuer Name and Ticker or Trading Symbol
    MeiraGTx Holdings plc [ MGTX ]
    5. Relationship of Reporting Person(s) to Issuer
    (Check all applicable)
    XDirectorX10% Owner
    Officer (give title below)Other (specify below)
    2a. Foreign Trading Symbol
    3. Date of Earliest Transaction (Month/Day/Year)
    08/02/2022
    6. Individual or Joint/Group Filing (Check Applicable Line)
    Form filed by One Reporting Person
    XForm filed by More than One Reporting Person
    4. If Amendment, Date of Original Filed (Month/Day/Year)

    Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
    1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
    CodeVAmount(A) or (D)Price
    Ordinary Shares04/17/2026A555,555A$910,786,658ISee Footnote(1)
    Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
    (e.g., puts, calls, warrants, options, convertible securities)
    1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
    CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
    Warrant (Right to Buy)$1508/02/2022A400,00008/02/202208/02/2027Ordinary Shares400,000(2)400,000ISee Footnote(2)
    Warrant (Right to Buy)$2008/02/2022A300,00008/02/202208/02/2027Ordinary Shares300,000(2)300,000ISee Footnote(2)
    Warrant (Right to Buy)$1503/25/2026D400,00008/02/202208/02/2027Ordinary Shares400,000(3)0ISee Footnote(2)
    Warrant (Right to Buy)$2003/25/2026D300,00008/02/202208/02/2027Ordinary Shares300,000(3)0ISee Footnote(2)
    Warrant (Right to Buy)$803/25/2026A400,00003/25/202608/02/2027Ordinary Shares400,000(3)400,000ISee Footnote(2)
    Warrant (Right to Buy)$803/25/2026A300,00003/25/202608/02/2027Ordinary Shares300,000(3)300,000ISee Footnote(2)
    1. Name and Address of Reporting Person*
    PERCEPTIVE ADVISORS LLC

    (Last)(First)(Middle)
    51 ASTOR PLACE, 10TH FLOOR

    (Street)
    NEW YORK NEW YORK 10003

    (City)(State)(Zip)

    UNITED STATES

    (Country)

    Relationship of Reporting Person(s) to Issuer
    XDirectorX10% Owner
    Officer (give title below)Other (specify below)
    1. Name and Address of Reporting Person*
    EDELMAN JOSEPH

    (Last)(First)(Middle)
    51 ASTOR PLACE, 10TH FLOOR

    (Street)
    NEW YORK NEW YORK 10003

    (City)(State)(Zip)

    UNITED STATES

    (Country)

    Relationship of Reporting Person(s) to Issuer
    XDirectorX10% Owner
    Officer (give title below)Other (specify below)
    1. Name and Address of Reporting Person*
    PERCEPTIVE LIFE SCIENCES MASTER FUND LTD

    (Last)(First)(Middle)
    51 ASTOR PLACE, 10TH FLOOR

    (Street)
    NEW YORK NEW YORK 10003

    (City)(State)(Zip)

    UNITED STATES

    (Country)

    Relationship of Reporting Person(s) to Issuer
    XDirectorX10% Owner
    Officer (give title below)Other (specify below)
    Explanation of Responses:
    1. The securities are directly held by Perceptive Life Sciences Master Fund Ltd. (the "Master Fund"). Perceptive Advisors LLC (the "Advisor") serves as the investment manager of Master Fund. Joseph Edelman is the managing member of the Advisor. Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.
    2. Issued to Perceptive Credit Holdings III, LP ("Credit Fund III") in connection with the senior secured financing arrangement (the "Financing Agreement") by and among the Issuer, PCH III, and the other parties thereto. Perceptive Credit Advisors LLC ("Perceptive Credit Advisors") serves as the investment advisor to Credit Fund III and as a relying advisor under the Advisor. Mr. Edelman is the managing member of Perceptive Credit Advisors. Each of Perceptive Credit Advisors, the Advisor and Mr. Edelman disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that any of Perceptive Credit Advisors, the Advisor and Mr. Edelman is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.
    3. On March 25, 2026, the Issuer, Credit Fund III, and the other parties to the Financing Agreement entered into an agreement whereby the exercise price of the warrants was adjusted to $8.00 per share.
    Remarks:
    Ellen Hukkelhoven, the Head of Investment Research of the Advisor, is a member of the Issuer's board of directors.
    /s/ Perceptive Advisors LLC, By: Joseph Edelman, its managing member04/23/2026
    /s/ Joseph Edelman - for Perceptive Life Sciences Master Fund Ltd., By: Perceptive Advisors LLC, its investment manager, By: Joseph Edelman, its managing member04/23/2026
    /s/ Joseph Edelman04/23/2026
    ** Signature of Reporting PersonDate
    Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
    * If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
    ** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
    Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
    Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
    * Form 4: SEC 1474 (03-26)
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