• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • AI Executive AssistantNEW
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • AI Executive AssistantNEW
  • Settings
  • RSS Feeds
PublishGo to AppAI Helper
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlertsPublish with Us
    Company
    AboutQuantisnow PlusContactJobsAI employees for your businessNEW
    Legal
    Terms of usePrivacy policyCookie policy

    Director Vitorovic Stefan was granted 1,028,674 shares (SEC Form 4)

    6/24/24 4:35:35 PM ET
    $AVRO
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $AVRO alert in real time by email
    SEC FORM 4 SEC Form 4
    FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549

    STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

    Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
    or Section 30(h) of the Investment Company Act of 1940
    OMB APPROVAL
    OMB Number: 3235-0287
    Estimated average burden
    hours per response: 0.5
      
    Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
      
    Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
    1. Name and Address of Reporting Person*
    Vitorovic Stefan

    (Last) (First) (Middle)
    C/O TECTONIC THERAPEUTIC, INC.
    490 ARSENAL WAY, SUITE 210

    (Street)
    WATERTOWN MA 02472

    (City) (State) (Zip)
    2. Issuer Name and Ticker or Trading Symbol
    Tectonic Therapeutic, Inc. [ TECX ]
    5. Relationship of Reporting Person(s) to Issuer
    (Check all applicable)
    X Director 10% Owner
    Officer (give title below) Other (specify below)
    3. Date of Earliest Transaction (Month/Day/Year)
    06/20/2024
    4. If Amendment, Date of Original Filed (Month/Day/Year)
    6. Individual or Joint/Group Filing (Check Applicable Line)
    X Form filed by One Reporting Person
    Form filed by More than One Reporting Person
    Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
    1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
    Code V Amount (A) or (D) Price
    Common Stock 06/20/2024 A 1,000,900 A (1) 1,000,900 I By LLC(2)
    Common Stock 06/20/2024 A 27,774 A (3) 27,774 I By LLC(4)
    Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
    (e.g., puts, calls, warrants, options, convertible securities)
    1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
    Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
    Stock Option (Right to Buy) $16.8 06/20/2024 A 11,760 (5) 06/19/2034 Common Stock 11,760 $0 11,760 D
    Explanation of Responses:
    1. Received in exchange for 1,872,873 shares of common stock held by Vida Ventures II, LLC ("VIDA II") of Tectonic Therapeutic, Inc., a Delaware corporation ("Tectonic"), pursuant to an Agreement and Plan of Merger dated as of January 30, 2024 (the "Merger Agreement") by and among AVROBIO, Inc., a Delaware corporation ("AVROBIO"), Tectonic and Alpine Merger Subsidiary, Inc., a direct, wholly owned subsidiary of AVROBIO (the "Merger Sub"). Under the terms of the Merger Agreement, on June 20, 2024, Merger Sub merged with and into Tectonic (the "Merger"), with Tectonic surviving the Merger as a wholly owned subsidiary of AVROBIO. Upon the closing of the Merger, each share of Tectonic common stock was converted into the right to receive 0.534419990 shares of the Issuer's common stock, after giving effect to a reverse stock split of the Issuer's common stock of 1-for-12. Subsequent to the Merger, the name of the Issuer was changed from AVROBIO, Inc. to Tectonic Therapeutic, Inc.
    2. The Reporting Person, through his position as a member of the investment committee of VV Manager II, LLC ("VV Manager"), the manager of VIDA II, may be deemed to have voting and dispositive power over the shares held by VIDA II. The Reporting Person disclaims beneficial ownership of the shares held by VIDA II, except to the extent of his pecuniary interest therein and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose.
    3. Received in exchange for 51,969 shares of common stock held by Vida Ventures II-A, LLC ("VIDA II-A") of Tectonic pursuant to the same terms and conditions as described in footnote (1) herein.
    4. The Reporting Person, through his position as a member of the investment committee of VV Manager, the manager of VIDA II-A, may be deemed to have voting and dispositive power over the shares held by VIDA II-A. The Reporting Person disclaims beneficial ownership of the shares held by VIDA II-A, except to the extent of his pecuniary interest therein and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose.
    5. 1/3rd of the shares subject to the option will vest on June 20, 2025, and the balance will vest in equal monthly installments thereafter over the next 24 months, subject in each case to the continuous service of the Reporting Person to the Issuer through the applicable vesting date.
    /s/ Daniel Lochner, Attorney-in-Fact 06/24/2024
    ** Signature of Reporting Person Date
    Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
    * If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
    ** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
    Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
    Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
    Get the next $AVRO alert in real time by email

    Crush Q3 2025 with the Best AI Executive Assistant

    Stay ahead of the competition with Tailforce.ai - your AI-powered business intelligence partner.

    AI-Powered Inbox
    Context-aware email replies
    Strategic Decision Support
    Get Started with Tailforce.ai

    Recent Analyst Ratings for
    $AVRO

    DatePrice TargetRatingAnalyst
    12/18/2023Buy → Neutral
    Mizuho
    1/6/2022$28.00 → $6.00Buy
    Mizuho
    1/5/2022$22.00 → $6.00Overweight
    Barclays
    1/5/2022$7.00 → $3.00Equal-Weight
    Morgan Stanley
    1/5/2022Buy → Neutral
    BTIG
    1/5/2022$28.00 → $8.00Buy
    Needham
    11/19/2021$24.00 → $7.00Overweight → Equal-Weight
    Morgan Stanley
    10/12/2021$27.00 → $25.00Overweight
    Morgan Stanley
    More analyst ratings

    $AVRO
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    See more
    • AVROBIO downgraded by Mizuho

      Mizuho downgraded AVROBIO from Buy to Neutral

      12/18/23 8:06:56 AM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Mizuho reiterated coverage on Avrobio with a new price target

      Mizuho reiterated coverage of Avrobio with a rating of Buy and set a new price target of $6.00 from $28.00 previously

      1/6/22 6:59:42 AM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Barclays reiterated coverage on Avrobio with a new price target

      Barclays reiterated coverage of Avrobio with a rating of Overweight and set a new price target of $6.00 from $22.00 previously

      1/5/22 9:51:19 AM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $AVRO
    Insider Purchases

    Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • Leonard Braden Michael bought $971,493 worth of shares (766,635 units at $1.27) (SEC Form 4)

      4 - AVROBIO, Inc. (0001681087) (Issuer)

      5/15/24 11:21:34 AM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $AVRO
    SEC Filings

    See more
    • AVROBIO Inc. filed SEC Form 8-K: Regulation FD Disclosure

      8-K - Tectonic Therapeutic, Inc. (0001681087) (Filer)

      6/25/24 9:52:20 PM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • AVROBIO Inc. filed SEC Form 8-K: Completion of Acquisition or Disposition of Assets, Financial Statements and Exhibits, Leadership Update, Entry into a Material Definitive Agreement, Changes in Registrant's Certifying Accountant, Results of Operations and Financial Condition, Material Modification to Rights of Security Holders, Changes in Control of Registrant

      8-K - Tectonic Therapeutic, Inc. (0001681087) (Filer)

      6/20/24 4:25:03 PM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Amendment: SEC Form 8-K/A filed by AVROBIO Inc.

      8-K/A - AVROBIO, Inc. (0001681087) (Filer)

      6/18/24 11:51:59 AM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $AVRO
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • Former 10% owner of AVROBIO Leonard Braden Michael acquired 433,688 shares (SEC Form 4)

      4 - Tectonic Therapeutic, Inc. (0001681087) (Issuer)

      6/25/24 1:42:11 PM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form 4 filed by Director Donenberg Phillip B.

      4 - Tectonic Therapeutic, Inc. (0001681087) (Issuer)

      6/24/24 4:37:33 PM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Director Vitorovic Stefan was granted 1,028,674 shares (SEC Form 4)

      4 - Tectonic Therapeutic, Inc. (0001681087) (Issuer)

      6/24/24 4:35:35 PM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $AVRO
    Press Releases

    Fastest customizable press release news feed in the world

    See more
    • Tectonic Therapeutic Appoints Daniel Lochner as Chief Financial Officer

      Tectonic Therapeutic, Inc. ("Tectonic"), a privately-held biotechnology company developing GPCR (G-protein coupled receptor)-targeted therapeutic proteins, today announced the appointment of Daniel Lochner as Chief Financial Officer of Tectonic. "Dan is an experienced public-company CFO who will add significant financial expertise to our team," said Alise Reicin, MD, President and Chief Executive Officer of Tectonic. "With his extensive background in the healthcare and biopharmaceutical industries, Dan is an important addition to the Tectonic team, and we are thrilled to welcome him as Chief Financial Officer." Dan brings with him a wealth of knowledge in corporate finance, business str

      6/3/24 4:15:00 PM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Tectonic Therapeutic Initiates Phase 1B Study for TX45 in Group 2 Pulmonary Hypertension in Patients with Preserved Ejection Fraction Heart Failure

      Study to evaluate TX45 impact on cardiopulmonary hemodynamics in patients with Group 2 Pulmonary Hypertension, a patient population in urgent need of novel therapies TX45 clinical program advancing on track based on promising initial Phase 1A data; confirmatory Phase 1A data expected mid-2024 and topline Phase 1B data expected in 2025 Tectonic Therapeutic, Inc. ("Tectonic"), a privately-held biotechnology company developing GPCR (G-protein coupled receptor)-targeted therapeutic proteins, co-founded by Timothy A. Springer and Andrew C. Kruse of Harvard Medical School, today announced the initiation of enrollment in the Phase 1B study for TX45, an investigational long-acting relaxin-Fc fu

      3/26/24 7:06:00 AM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Tectonic Therapeutic Announces Participation at Investor Conferences in March

      Tectonic Therapeutic, Inc. ("Tectonic"), a privately-held biotechnology company developing GPCR (G-protein coupled receptor)-targeted therapeutic proteins, co-founded by Timothy A. Springer and Andrew C. Kruse of Harvard Medical School, today announced that Alise Reicin, MD, President and Chief Executive Officer, will be participating in two investor conferences in March: TD Cowen 44th Annual Health Care Conference being held in Boston on March 4 – 6 Leerink Partners Global Biopharma Conference being held in Miami on March 11 – 13 The Tectonic management team will host one-on-one meetings during both conferences. Interested investors should contact their TD Cowen and/or Leerink rep

      2/27/24 7:00:00 AM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $AVRO
    Leadership Updates

    Live Leadership Updates

    See more
    • Tectonic Therapeutic Appoints Daniel Lochner as Chief Financial Officer

      Tectonic Therapeutic, Inc. ("Tectonic"), a privately-held biotechnology company developing GPCR (G-protein coupled receptor)-targeted therapeutic proteins, today announced the appointment of Daniel Lochner as Chief Financial Officer of Tectonic. "Dan is an experienced public-company CFO who will add significant financial expertise to our team," said Alise Reicin, MD, President and Chief Executive Officer of Tectonic. "With his extensive background in the healthcare and biopharmaceutical industries, Dan is an important addition to the Tectonic team, and we are thrilled to welcome him as Chief Financial Officer." Dan brings with him a wealth of knowledge in corporate finance, business str

      6/3/24 4:15:00 PM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • AVROBIO and Tectonic Therapeutic Announce Merger

      Combined company to be Nasdaq-listed, clinical-stage biopharmaceutical company focused on advancing Tectonic's novel GPCR-targeted therapeutic proteins $130.7 million in private financing commitments with new and existing leading life sciences investors in connection with merger Combined company expected to have approximately $165 million in cash and cash equivalents at close to provide cash runway into mid-2027 Funding is expected to advance lead asset TX45, a potential best-in-class Fc-relaxin fusion protein, through multiple clinical data catalysts Tectonic's first two programs address indications with high unmet need and no approved therapies Companies to host joint webcast to

      1/30/24 8:00:00 AM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • AVROBIO Reports First Quarter 2023 Financial Results and Provides Business Update

      On track to initiate registrational global Phase 2/3 clinical trial for Gaucher disease type 3 (GD3) in second half 2023, subject to regulatory alignment Plan to provide clinical and regulatory updates on cystinosis program in conjunction with ASGCT annual meeting in May 2023; plan to initiate late-stage cystinosis clinical trial activities in second half 2023, subject to regulatory alignment Collaborator-sponsored Phase 1/2 clinical trial for mucopolysaccharidosis type II (MPS-II), or Hunter syndrome, initiated Announced appointment of current CFO Erik Ostrowski as interim CEO AVROBIO, Inc. (NASDAQ:AVRO), a leading clinical-stage gene therapy company working to free people from a l

      5/11/23 7:00:00 AM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $AVRO
    Financials

    Live finance-specific insights

    See more
    • AVROBIO Reports Fourth Quarter and Fiscal Year 2021 Financial Results and Provides Business Update

      Provided interim data at WORLDSymposium™ 2022 that showed sustained engraftment across first three patients 1+ year post-gene therapy in Phase 1/2 clinical triali for cystinosis; all remain off oral cysteamine to date Interim clinical data update of AVR-RD-02 in Gaucher disease type 1 planned for 2022; third patient dosed in Phase 1/2 clinical trial Regulatory interactions planned in 2022 to inform clinical development and registration strategies for programs in Gaucher disease, cystinosis, Hunter syndrome and Pompe disease Strong balance sheet with cash runway into Q1 2024 AVROBIO, Inc. (NASDAQ:AVRO), a leading clinical-stage gene therapy company with a mission to free people from a li

      3/17/22 7:00:00 AM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • AVROBIO Reports Interim Data from Phase 1/2 Clinical Trial of Investigational Gene Therapy for Cystinosis

      Sustained engraftment observed across first three patients 1+ year post-gene therapy; all remain off oral cysteamine to date Reduction in number of cystine crystals as measured in skin and intestinal mucosa biopsies observed across first three patients Continued favorable safety profile with no adverse events related to drug product to date Clinical proof-of-concept in adult patients lays groundwork for AVROBIO-sponsored trial planned to begin in 2023 Analyst and investor conference call scheduled for today at 8:00 a.m. ET AVROBIO, Inc. (NASDAQ:AVRO), a leading clinical-stage gene therapy company with a shared purpose to free people from a lifetime of genetic disease, today reported

      2/9/22 7:00:00 AM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • AVROBIO to Present New Data from Phase 1/2 Clinical Trial in Cystinosis at WORLDSymposium™ 2022

      Analyst and investor conference call scheduled for Wednesday, Feb. 9, 2022, at 8:00 a.m. ET Five platform presentations and three posters on the company's clinical and preclinical programs for lysosomal disorders are scheduled throughout the symposium AVROBIO, Inc. (NASDAQ:AVRO), a leading clinical-stage gene therapy company with a mission to free people from a lifetime of genetic disease, today announced that updated clinical data from its ongoing, collaborator-sponsoredi Phase 1/2 clinical trial in cystinosis will be presented on Feb. 9, 2022, at the 18th Annual WORLDSymposium™ in San Diego, Calif. Additionally, preclinical data from its Pompe disease and Hunter syndrome programs, as we

      1/27/22 7:00:00 AM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $AVRO
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    See more
    • SEC Form SC 13D filed by AVROBIO Inc.

      SC 13D - Tectonic Therapeutic, Inc. (0001681087) (Subject)

      6/26/24 8:00:02 AM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form SC 13D filed by AVROBIO Inc.

      SC 13D - Tectonic Therapeutic, Inc. (0001681087) (Subject)

      6/25/24 4:23:25 PM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form SC 13G/A filed by AVROBIO Inc. (Amendment)

      SC 13G/A - AVROBIO, Inc. (0001681087) (Subject)

      5/21/24 10:01:24 AM ET
      $AVRO
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care