• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • AI SuperconnectorNEW
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • AI SuperconnectorNEW
  • Settings
  • RSS Feeds
PublishGo to AppAI Superconnector
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlertsPublish with Us
    Company
    AboutQuantisnow PlusContactJobsAI superconnector for talent & startupsNEWLLM Arena
    Legal
    Terms of usePrivacy policyCookie policy

    Direxion Launches mRNA ETF (MSGR)

    12/9/21 8:41:00 AM ET
    $ALNY
    $ARWR
    $BGNE
    $BNTX
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $ALNY alert in real time by email

    NEW YORK, Dec. 9, 2021 /PRNewswire/ -- Direxion announced today the launch of the Direxion mRNA ETF (Ticker: MSGR). MSGR invests in companies believed to be at the forefront of the development and application of messenger RNA technology.

    The MSGR ETF seeks investment results, before fees and expenses, of the BITA Messenger RNA Technology Index. The BITA Messenger RNA Technology Index provides exposure to the performance of companies, publicly listed in the United States, Canada and Europe, that are leading the development and application of mRNA technology. mRNA is a single-stranded ribonucleic acid molecule that is complementary to one of the DNA strands of a gene. mRNA plays a vital role in protein synthesis in the human body, and mRNA technologies leverage this vital role to enable targeted cells to produce proteins that enable the body to fight, or prevent, a given disease.

    "For years, messenger RNA (mRNA) technologies struggled to gain acceptance. The COVID-19 pandemic changed all of that, thanks to the highly effective vaccines developed using mRNA to combat the novel coronavirus and its emerging variants," said David Mazza, Managing Director, Head of Product at Direxion. "MSGR captures companies specifically involved with mRNA technologies that are believed to be at the forefront of fighting the battle against COVID, while also highlighting mRNA's application to other viruses and diseases, including HIV and Lyme disease."

    Investors seeking to gain exposure to mRNA stocks, and the mRNA sector, can access companies such as Moderna, Inc. (MRNA), BioNTech SE (BNTX), Vertex Pharmaceuticals Inc (VRTX) and others through this mRNA ETF ($MSGR). For additional nanotech stocks, see the table below.

    As of November 19, 2021, the 24 constituents had a median total market capitalization of $2 billion, total market capitalizations ranging from $41 million to $107 billion, and were concentrated in the healthcare sector. Top ten index holdings are as follows:

    mRNA ETF ( Ticker: MSGR) Index Holdings

    Name

    Ticker

    GICS Sub-Industry

    Market

    Cap ($B)

    Weight

    (%)

    BioNTech SE

    BNTX

    Biotechnology

    85.30

    9.41

    Dicerna Pharmaceuticals Inc

    DRNA

    Pharmaceuticals

    2.96

    8.22

    Vertex Pharmaceuticals Inc

    VRTX

    Pharmaceuticals

    47.53

    7.07

    Moderna Inc

    MRNA

    Biotechnology & Pharmaceuticals

    142.89

    7.04

    BeiGene Ltd

    BGNE

    Biotechnology

    32.45

    6.64

    Alnylam Pharmaceuticals Inc

    ALNY

    Pharmaceuticals

    21.98

    6.50

    Gritstone bio Inc

    GRTS

    Biotechnology

    0.90

    5.34

    Arrowhead Pharmaceuticals Inc

    ARWR

    Pharmaceuticals

    7.32

    4.90

    Maravai LifeSciences Holdings Inc

    MRVI

    Biotechnology

    11.84

    4.65

    CureVac NV

    CVAC

    Biotechnology

    9.00

    4.54

    Source: Source: Bloomberg Finance, L.P., BITA, as of 11.30.2021.

    About Direxion:

    Direxion equips traders with ways to execute short-term, tactical trades and investors with strategic exposures, and thematic strategies, focused on emerging trends. Founded in 1997, the company has approximately $25.1 billion in assets under management as of September 30, 2021. For more information, please visit www.direxion.com.   

    ###

    For more information on all Direxion Shares daily leveraged ETFs, go to direxion.com, or call us at 866.476.7523.

    An investor should carefully consider a Fund's investment objective, risks, charges, and expenses before investing. A Fund's prospectus and summary prospectus contain this and other information about the Direxion Shares. To obtain a Fund's prospectus and summary prospectus call 866-716-0735 or visit our website at direxion.com. A Fund's prospectus and summary prospectus should be read carefully before investing.

    Direxion Shares Risks –  Investing involves risk including possible loss of principal. There is no guarantee the investment strategy will be successful. mRNA technology is a novel technology and the development of products or therapies based on mRNA technology has substantial clinical development and regulatory risks. mRNA technologies may also provide ineffective or may produce adverse effects. Negative perception of the efficacy, safety, or tolerability of such mRNA-based products or therapies could adversely affect a company and the general acceptance of mRNA technologies. Certain mRNA-based vaccines only have received Emergency Use Authorization from the U.S. Food and Drug Administration and other provisional, interim or conditional authorizations from regulatory authorities outside the United States, and there is no guarantee that such vaccines will receive full approval in the future.

    Additional risks of the Fund include, but are not limited to, Non-Diversification Risk, Index Correlation/Tracking Risk, Index Strategy Risk, Biotechnology Industry Risk, Healthcare Sector Risk, Natural Disaster/Epidemic and Market Disruption Risk, Foreign Securities Risk and risks associated with the market capitalizations and sectors of the securities in which the Fund may invest. Please see the summary and full prospectuses for a more complete description of these and other risks of the Fund.

    Distributor: Foreside Fund Services, LLC.

    CONTACT:   

    James Doyle



    JConnelly



    973.850.7308



    [email protected]

     

    Cision View original content:https://www.prnewswire.com/news-releases/direxion-launches-mrna-etf-msgr-301441238.html

    SOURCE Direxion

    Get the next $ALNY alert in real time by email

    Crush Q3 2025 with the Best AI Superconnector

    Stay ahead of the competition with Standout.work - your AI-powered talent-to-startup matching platform.

    AI-Powered Inbox
    Context-aware email replies
    Strategic Decision Support
    Get Started with Standout.work

    Recent Analyst Ratings for
    $ALNY
    $ARWR
    $BGNE
    $BNTX

    CompanyDatePrice TargetRatingAnalyst
    Vertex Pharmaceuticals Incorporated
    $VRTX
    11/13/2025$495.00Sector Outperform
    Scotiabank
    Vertex Pharmaceuticals Incorporated
    $VRTX
    9/25/2025$456.00Market Perform → Outperform
    Leerink Partners
    Vertex Pharmaceuticals Incorporated
    $VRTX
    9/3/2025Mkt Perform
    Raymond James
    Vertex Pharmaceuticals Incorporated
    $VRTX
    8/6/2025$460.00Equal Weight → Overweight
    Wells Fargo
    Alnylam Pharmaceuticals Inc.
    $ALNY
    8/4/2025Underperform → Peer Perform
    Wolfe Research
    Alnylam Pharmaceuticals Inc.
    $ALNY
    8/4/2025$490.00Perform → Outperform
    Oppenheimer
    Alnylam Pharmaceuticals Inc.
    $ALNY
    7/30/2025$370.00Outperform
    Raymond James
    Alnylam Pharmaceuticals Inc.
    $ALNY
    7/21/2025$385.00Buy
    Truist
    More analyst ratings

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    SEC Filings

    View All

    SEC Form SC TO-I filed by Moderna Inc.

    SC TO-I - Moderna, Inc. (0001682852) (Subject)

    11/13/25 8:21:12 AM ET
    $MRNA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form SC TO-C filed by Moderna Inc.

    SC TO-C - Moderna, Inc. (0001682852) (Subject)

    11/12/25 5:21:39 PM ET
    $MRNA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form 425 filed by CureVac N.V.

    425 - CureVac N.V. (0001809122) (Subject)

    11/12/25 8:01:22 AM ET
    $CVAC
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    View All

    Scotiabank initiated coverage on Vertex Pharma with a new price target

    Scotiabank initiated coverage of Vertex Pharma with a rating of Sector Outperform and set a new price target of $495.00

    11/13/25 9:17:56 AM ET
    $VRTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Vertex Pharma upgraded by Leerink Partners with a new price target

    Leerink Partners upgraded Vertex Pharma from Market Perform to Outperform and set a new price target of $456.00

    9/25/25 8:24:14 AM ET
    $VRTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Raymond James initiated coverage on Vertex Pharma

    Raymond James initiated coverage of Vertex Pharma with a rating of Mkt Perform

    9/3/25 8:40:38 AM ET
    $VRTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    Insider Purchases

    Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

    View All

    CEO & President Kewalramani Reshma bought $3,895,768 worth of shares (10,000 units at $389.58), increasing direct ownership by 9% to 115,968 units (SEC Form 4)

    4 - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Issuer)

    8/7/25 4:23:31 PM ET
    $VRTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Director Sachs Bruce I bought $1,948,416 worth of shares (5,000 units at $389.68), increasing direct ownership by 12% to 45,000 units (SEC Form 4)

    4 - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Issuer)

    8/7/25 4:19:03 PM ET
    $VRTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Director Reitan Colleen F bought $10,363 worth of shares (36 units at $287.85), sold $8,383 worth of shares (36 units at $232.86) and was granted 775 shares (SEC Form 4)

    4 - ALNYLAM PHARMACEUTICALS, INC. (0001178670) (Issuer)

    5/12/25 4:05:00 PM ET
    $ALNY
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    Press Releases

    Fastest customizable press release news feed in the world

    View All

    Maravai LifeSciences Announces November 2025 Investor Conference Schedule

    Maravai LifeSciences, Inc. (NASDAQ:MRVI), a global provider of life science reagents and services to researchers and biotech innovators, is scheduled to participate in the following investor conference during the month of November. On November 12, 2025, at 10:00 a.m. EST, Raj Asarpota, Chief Financial Officer, will participate in a fireside chat at the Stifel Healthcare Conference in New York City, NY. On November 19, 2025, at 10:00 a.m. GMT, Raj Asarpota, Chief Financial Officer, will participate in a fireside chat at the Jefferies Healthcare Conference in London, England. A live webcast of each presentation will be available to all interested parties on the Maravai LifeSciences Investo

    11/10/25 8:00:00 AM ET
    $MRVI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Vertex Presents Updated Phase 1/2 Data From RUBY-3 Study That Continue to Demonstrate Best-in-Class Potential for Povetacicept in Adults with IgA Nephropathy and Primary Membranous Nephropathy at American Society of Nephrology Kidney Week

    - 48-week data show a 64% decrease from baseline in proteinuria in IgA nephropathy, 82% decrease from baseline in proteinuria in primary membranous nephropathy, and stabilization of estimated glomerular filtration rate across both diseases - - Vertex on track to initiate rolling submission of Biologics License Application for potential accelerated approval to the U.S. Food and Drug Administration this year; full enrollment completed for Phase 3 RAINIER trial in IgA nephropathy - - Povetacicept in primary membranous nephropathy granted Fast Track Designation by the U.S. Food and Drug Administration and Phase 2/3 pivotal trial initiated - Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX

    11/8/25 5:15:00 PM ET
    $VRTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    New Post Hoc Analysis from the HELIOS-B Phase 3 Study Shows Vutrisiran Improved Measures of Heart Structure and Function in Patients with ATTR-CM

    − Analyses Presented at the American Heart Association Scientific Sessions 2025 Underscore Vutrisiran's Differentiated Profile – − Cardiovascular Magnetic Resonance (CMR) and Echocardiographic Analyses Demonstrate that Treatment with Vutrisiran Resulted in Significant Changes on Multiple Functional and Structural Cardiac Parameters – – In a Cohort of HELIOS-B Patients, CMR Imaging Showed Amyloid Regression in 22% of Vutrisiran Treated Patients with No Regression Found in Patients Who Received Placebo – – Treatment with Vutrisiran Preserved Kidney Function in HELIOS-B Patients, and Reduced Risk of Death and Cardiovascular Events in Patients with Advanced Chronic Kidney Disease – Alny

    11/8/25 4:57:00 PM ET
    $ALNY
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    FDA approvals

    Live FDA approvals issued by the Food and Drug Administration and FDA breaking news

    View All

    January 30, 2025 - FDA Approves Novel Non-Opioid Treatment for Moderate to Severe Acute Pain

    For Immediate Release: January 30, 2025 Today, the U.S. Food and Drug Administration approved Journavx (suzetrigine) 50 milligram oral tablets, a first-in-class non-opioid analgesic, to treat moderate to severe acute pain in adults. Journavx reduces pain by targeting a pain-signaling pathway involving sodium channels in the peripheral nervous system, before pain signals reach the brain.  Journavx is the first dr

    1/30/25 5:46:14 PM ET
    $VRTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    FDA Approval for GIVLAARI issued to ALNYLAM PHARMS INC

    Submission status for ALNYLAM PHARMS INC's drug GIVLAARI (SUPPL-7) with active ingredient GIVOSIRAN SODIUM has changed to 'Approval' on 04/29/2024. Application Category: NDA, Application Number: 212194, Application Classification: Labeling

    4/30/24 1:44:03 PM ET
    $ALNY
    Biotechnology: Pharmaceutical Preparations
    Health Care

    December 8, 2023 - FDA Approves First Gene Therapies to Treat Patients with Sickle Cell Disease

    For Immediate Release: December 08, 2023 Today, the U.S. Food and Drug Administration approved two milestone treatments, Casgevy and Lyfgenia, representing the first cell-based gene therapies for the treatment of sickle cell disease (SCD) in patients 12 years and older. Additionally, one of these therapies, Casgevy, is the first FDA-approved treatment to utilize a type of novel genome editing technology, signali

    12/8/23 11:12:21 AM ET
    $BLUE
    $VRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Biotechnology: Pharmaceutical Preparations

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    View All

    SEC Form 4 filed by Director Upadhyay Suketu

    4 - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Issuer)

    10/17/25 4:05:46 PM ET
    $VRTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 4 filed by Director Sachs Bruce I

    4 - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Issuer)

    10/17/25 4:04:06 PM ET
    $VRTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Chief Financial Officer Mock James M covered exercise/tax liability with 703 shares and converted options into 1,453 shares, increasing direct ownership by 4% to 18,259 units (SEC Form 4)

    4 - Moderna, Inc. (0001682852) (Issuer)

    10/6/25 4:23:23 PM ET
    $MRNA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    Leadership Updates

    Live Leadership Updates

    View All

    BioNTech to Host Innovation Series R&D Day on November 11, 2025

    MAINZ, Germany, October 28, 2025 (GLOBE NEWSWIRE) -- BioNTech SE (NASDAQ:BNTX, "BioNTech" or "the Company")), will host an edition of the Company's Innovation Series R&D Day at 09:00 a.m. Eastern Standard Time (3:00 p.m. CET) on Tuesday, November 11, 2025 in New York City, U.S. On the day, members of BioNTech's leadership team will provide an overview of the Company's strategy and clinical progress across its pipeline. Investors, analysts and the interested public are invited to join the event online via this link. A replay of the webcast will be available shortly after the conclusion of the event and archived on the Company's website for one year following the call. The public may also

    10/28/25 7:45:00 AM ET
    $BNTX
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Alnylam Pharmaceuticals joins Alliance for Genomic Discovery, expanding diverse clinical genomic dataset to drive precision medicine

    Alnylam, a leader in RNA interference (RNAi) therapeutics, will utilize the AGD dataset to inform development of 'gene silencing' medicines Members leverage AI-powered dataset to accelerate pharma R&D, and ensure that disease-impacting discoveries benefit all people SAN DIEGO, Sept. 18, 2025 /PRNewswire/ -- Illumina, Inc. (NASDAQ:ILMN), and Nashville Biosciences, LLC (NashBio), today announced Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) (Alnylam) as a member of the Alliance for Genomic Discovery (AGD). Alnylam, a pioneer in RNA interference (RNAi) therapeutics, will utilize the AGD clinical genomic database to derive real-world insights and accelerate drug target discovery.

    9/18/25 9:15:00 AM ET
    $ALNY
    $ILMN
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Medical Specialities

    Ajit Singh Appointed CEO of Harbinger Health and CEO-Partner of Flagship Pioneering

    Stephen Hahn to Transition to CEO Emeritus and Special Advisor and remain on Harbinger's board CAMBRIDGE, Mass., Aug. 11, 2025 /PRNewswire/ -- Flagship Pioneering, the bioplatform innovation company, and Harbinger Health, a biotechnology company pioneering the detection of early cancer, today announced the appointment of Ajit Singh, Ph.D. as CEO-Partner of Flagship and the new CEO of Harbinger.  Dr. Singh, a veteran of the diagnostics industry, will also continue as a Harbinger board member, a role he has held since 2024. Dr. Singh succeeds Stephen Hahn, M.D., who will transition from his role as CEO and remain closely involved with the company as CEO Emeritus and Special Advisor. He will co

    8/11/25 12:00:00 PM ET
    $FHTX
    $MRNA
    $SANA
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Biotechnology: Biological Products (No Diagnostic Substances)

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    View All

    Amendment: SEC Form SC 13D/A filed by BeiGene Ltd.

    SC 13D/A - BeiGene, Ltd. (0001651308) (Subject)

    12/10/24 9:30:34 PM ET
    $BGNE
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Amendment: SEC Form SC 13D/A filed by BeiGene Ltd.

    SC 13D/A - BeiGene, Ltd. (0001651308) (Subject)

    12/4/24 4:05:33 PM ET
    $BGNE
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Amendment: SEC Form SC 13G/A filed by Maravai LifeSciences Holdings Inc.

    SC 13G/A - MARAVAI LIFESCIENCES HOLDINGS, INC. (0001823239) (Subject)

    11/14/24 7:49:19 PM ET
    $MRVI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $ALNY
    $ARWR
    $BGNE
    $BNTX
    Financials

    Live finance-specific insights

    View All

    Arrowhead Pharmaceuticals to Webcast Fiscal 2025 Year-End Results

    Arrowhead Pharmaceuticals, Inc. (NASDAQ:ARWR) today announced that it will host a webcast and conference call on November 25, 2025, at 4:30 p.m. ET to discuss its financial results for the 2025 fiscal year ended September 30, 2025. Webcast and Conference Call Details Investors may access a live audio webcast on the Events and Presentations page under the Investors section of the Arrowhead website. A replay of the webcast will be available approximately two hours after the conclusion of the call. For analysts that wish to participate in the conference call, please register at https://register-conf.media-server.com/register/BI2700430252ab408a89dff83808477869. Once registered, you will rece

    11/6/25 4:30:00 PM ET
    $ARWR
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Maravai LifeSciences Reports Third Quarter 2025 Financial Results

    Organizational restructuring and operating cost reduction initiatives on track Maravai LifeSciences Holdings, Inc. (Maravai) (NASDAQ:MRVI), a global provider of life science reagents and services to researchers and biotech innovators, today reported financial results for the third quarter ended September 30, 2025, together with other business updates. Quarterly Results: Revenue of $41.6 million, Net loss of $(45.1) million, and Adjusted EBITDA of $(10.8) million "We exited the third quarter confident about the future of our business. Cygnus continues to perform well and TriLink, although lumpy by nature, shows strong funnel and order velocity. We expect TriLink to deliver double digit

    11/6/25 4:01:00 PM ET
    $MRVI
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Vertex Reports Third Quarter 2025 Financial Results

    — Total revenue of $3.08 billion, an 11% increase compared to Q3 2024 — — Refined full year financial guidance: total revenue guidance now $11.9 to $12.0 billion and total combined non-GAAP R&D, AIPR&D, and SG&A expense guidance now $5.0 to $5.1 billion — — R&D pipeline continues to make progress: five programs in pivotal development and povetacicept Phase 3 IgAN trial full enrollment complete; on track to submit first module of povetacicept IgAN BLA to FDA by end of 2025 — Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) today reported consolidated financial results for the third quarter ended September 30, 2025, and refined full year 2025 financial guidance. "Vertex delivered str

    11/3/25 4:02:00 PM ET
    $VRTX
    Biotechnology: Pharmaceutical Preparations
    Health Care