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    Vertex Pharmaceuticals Incorporated

    Subscribe to $VRTX
    $VRTX
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Vertex Pharmaceuticals Incorporated engages in developing and commercializing therapies for treating cystic fibrosis. The company markets SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO to treat patients with cystic fibrosis who have specific mutations in their cystic fibrosis transmembrane conductance regulator gene; and TRIKAFTA for the treatment of patients with CF 12 years of age or older who have at least one F508del mutation in the cystic fibrosis transmembrane conductance regulator, or CFTR, gene. Its pipeline includes Pipeline for Alpha-1 antitrypsin deficiency that is in Phase 2 clinical trial; VX-864, a second investigational small molecule corrector for the treatment of AAT deficiency, which is in Phase 1 clinical trial; and VX-147 that completed a Phase 1 clinical trial for the treatment of APOL1-mediated focal segmental glomerulosclerosis, or FSGS, and other serious kidney diseases. The company sells its products primarily to specialty pharmacy and specialty distributors in the United States, as well as specialty distributors and retail chains, and hospitals and clinics internationally. Vertex Pharmaceuticals Incorporated has collaborations with CRISPR Therapeutics AG; Arbor Biotechnologies, Inc.; Moderna, Inc.; Genomics plc; Merck KGaA; Darmstadt, Germany; X-Chem, Inc.; Janssen Pharmaceuticals, Inc.; Merck KGaA; Kymera Therapeutics; Ribometrix, Inc.; Molecular Templates, Inc.; and Affinia Therapeutics, as well as a strategic research collaboration and licensing agreement with Obsidian Therapeutics, Inc. for the discovery of novel therapies that regulate gene editing for the treatment of serious diseases. The company was founded in 1989 and is headquartered in Boston, Massachusetts.

    IPO Year: 1991

    Exchange: NASDAQ

    Website: vrtx.com

    Peers

    $JAZZ
    $VERX

    Recent Analyst Ratings for Vertex Pharmaceuticals Incorporated

    DatePrice TargetRatingAnalyst
    5/7/2025Outperform → Peer Perform
    Wolfe Research
    5/6/2025$503.00Outperform → Market Perform
    Leerink Partners
    4/22/2025$535.00Overweight
    Cantor Fitzgerald
    2/12/2025$408.00 → $424.00Sell → Hold
    Canaccord Genuity
    2/11/2025Sell → Hold
    Canaccord Genuity
    1/30/2025$460.00Overweight → Equal Weight
    Wells Fargo
    12/20/2024$600.00 → $535.00Buy
    H.C. Wainwright
    12/19/2024Outperform → Perform
    Oppenheimer
    12/9/2024$500.00 → $550.00Hold → Buy
    Jefferies
    11/14/2024$575.00Buy
    Citigroup
    See more ratings

    Vertex Pharmaceuticals Incorporated Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

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    • New insider Mckechnie Duncan claimed ownership of 16,130 shares (SEC Form 3)

      3 - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Issuer)

      7/2/25 4:20:57 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • EVP, COO Arbuckle Stuart A covered exercise/tax liability with 37,243 shares, decreasing direct ownership by 37% to 63,368 units (SEC Form 4)

      4 - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Issuer)

      7/2/25 4:16:51 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • EVP, Chief Scientific Officer Altshuler David sold $22,084 worth of shares (52 units at $424.69), decreasing direct ownership by 0.22% to 23,281 units (SEC Form 4)

      4 - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Issuer)

      5/19/25 5:07:43 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • EVP, COO Arbuckle Stuart A was granted 37,622 shares, increasing direct ownership by 60% to 100,611 units (SEC Form 4)

      4 - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Issuer)

      5/15/25 4:10:28 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Director Upadhyay Suketu returned 1,001 shares to the company and was granted 796 shares, decreasing direct ownership by 8% to 2,354 units (SEC Form 4)

      4 - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Issuer)

      5/5/25 5:00:58 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Director Thornberry Nancy was granted 398 shares, increasing direct ownership by 24% to 2,035 units (SEC Form 4)

      4 - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Issuer)

      5/5/25 4:59:17 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Director Schneider Jennifer was granted 796 shares, increasing direct ownership by 86% to 1,718 units (SEC Form 4)

      4 - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Issuer)

      5/5/25 4:57:54 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Director Sachs Bruce I

      4 - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Issuer)

      5/5/25 4:55:45 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Director Mckenzie Diana was granted 796 shares and returned 1,001 shares to the company, decreasing direct ownership by 8% to 2,231 units (SEC Form 4)

      4 - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Issuer)

      5/5/25 4:52:27 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Director Lagarde Michel

      4 - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Issuer)

      5/5/25 4:20:54 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    Vertex Pharmaceuticals Incorporated Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

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    • Vertex Pharma downgraded by Wolfe Research

      Wolfe Research downgraded Vertex Pharma from Outperform to Peer Perform

      5/7/25 8:37:12 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Pharma downgraded by Leerink Partners with a new price target

      Leerink Partners downgraded Vertex Pharma from Outperform to Market Perform and set a new price target of $503.00

      5/6/25 8:04:29 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Cantor Fitzgerald resumed coverage on Vertex Pharma with a new price target

      Cantor Fitzgerald resumed coverage of Vertex Pharma with a rating of Overweight and set a new price target of $535.00

      4/22/25 7:35:34 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Pharma upgraded by Canaccord Genuity with a new price target

      Canaccord Genuity upgraded Vertex Pharma from Sell to Hold and set a new price target of $424.00 from $408.00 previously

      2/12/25 7:48:18 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Pharma upgraded by Canaccord Genuity

      Canaccord Genuity upgraded Vertex Pharma from Sell to Hold

      2/11/25 1:34:52 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Pharma downgraded by Wells Fargo with a new price target

      Wells Fargo downgraded Vertex Pharma from Overweight to Equal Weight and set a new price target of $460.00

      1/30/25 7:18:44 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • H.C. Wainwright reiterated coverage on Vertex Pharma with a new price target

      H.C. Wainwright reiterated coverage of Vertex Pharma with a rating of Buy and set a new price target of $535.00 from $600.00 previously

      12/20/24 8:26:52 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Pharma downgraded by Oppenheimer

      Oppenheimer downgraded Vertex Pharma from Outperform to Perform

      12/19/24 1:32:51 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Pharma upgraded by Jefferies with a new price target

      Jefferies upgraded Vertex Pharma from Hold to Buy and set a new price target of $550.00 from $500.00 previously

      12/9/24 8:38:26 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Citigroup initiated coverage on Vertex Pharma with a new price target

      Citigroup initiated coverage of Vertex Pharma with a rating of Buy and set a new price target of $575.00

      11/14/24 7:59:12 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    Vertex Pharmaceuticals Incorporated SEC Filings

    See more
    • SEC Form 144 filed by Vertex Pharmaceuticals Incorporated

      144 - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Subject)

      5/21/25 4:58:00 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Pharmaceuticals Incorporated filed SEC Form 8-K: Other Events

      8-K - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Filer)

      5/19/25 4:24:32 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Pharmaceuticals Incorporated filed SEC Form 8-K: Submission of Matters to a Vote of Security Holders

      8-K - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Filer)

      5/14/25 4:08:09 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 10-Q filed by Vertex Pharmaceuticals Incorporated

      10-Q - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Filer)

      5/6/25 4:04:39 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Pharmaceuticals Incorporated filed SEC Form 8-K: Results of Operations and Financial Condition, Financial Statements and Exhibits

      8-K - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Filer)

      5/5/25 4:10:03 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form DEFA14A filed by Vertex Pharmaceuticals Incorporated

      DEFA14A - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Filer)

      4/3/25 4:04:58 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form DEF 14A filed by Vertex Pharmaceuticals Incorporated

      DEF 14A - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Filer)

      4/3/25 4:02:48 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Pharmaceuticals Incorporated filed SEC Form 8-K: Other Events

      8-K - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Filer)

      3/28/25 4:08:01 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form S-3ASR filed by Vertex Pharmaceuticals Incorporated

      S-3ASR - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Filer)

      2/13/25 5:14:16 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 10-K filed by Vertex Pharmaceuticals Incorporated

      10-K - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Filer)

      2/13/25 4:01:52 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    Vertex Pharmaceuticals Incorporated Press Releases

    Fastest customizable press release news feed in the world

    See more
    • Breaking Through: Systemic Genetic Medicines for Hard-to-Treat Cancers

      NetworkNewsWire Editorial Coverage NEW YORK, July 9, 2025 /PRNewswire/ -- Each year, approximately 20 million people are diagnosed with cancer, and nearly 10 million lives are lost to the disease worldwide, a toll that is projected to rise in the coming decades (https://ibn.fm/dyQrw). By 2050, the American Cancer Society estimates that annual cancer diagnoses will reach 35 million. While advances in treatment have improved outcomes for some patients, the demand for more effective therapies remains urgent — and the opportunity for innovation and market impact is significant. Calidi Biotherapeutics Inc. (NYSE:CLDI) (Profile) is taking a bold approach to this challenge with a next-generation pl

      7/9/25 8:30:00 AM ET
      $CLDI
      $CRSP
      $CTMX
      $IBRX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
      Biotechnology: Pharmaceutical Preparations
    • Vertex to Announce Second Quarter 2025 Financial Results on August 4th

      Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) will report its second quarter 2025 financial results on Monday, August 4, 2025 after the financial markets close. The company will host a conference call and webcast at 4:30 p.m. ET. To access the call, please dial (833) 630-2124 (U.S.) or +1 (412) 317-0651 (International) and reference the "Vertex Pharmaceuticals Second Quarter 2025 Earnings Call." The conference call will be webcast live and a link to the webcast can be accessed through Vertex's website at www.vrtx.com in the "Investors" section. To ensure a timely connection, it is recommended that participants register at least 15 minutes prior to the scheduled webcast. An archived we

      7/8/25 4:00:00 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Precision Genetic Medicine Platform Could Disrupt Standard of Care in Metastatic Cancer, Other Indications of Unmet Needs

      NetworkNewsWire Editorial Coverage NEW YORK, July 7, 2025 /PRNewswire/ -- An estimated 20 million people are diagnosed annually with cancer, while cancer kills almost 10 million people a year worldwide (https://ibn.fm/dyQrw) with these numbers expected to grow. The American Cancer Society projects that by 2050, 35 million people will be diagnosed with cancer every year. Despite significant progress made in treating the disease, there is still a desperate need — and an enormous market potential — for new and more effective cancer drugs. Calidi Biotherapeutics Inc. (NYSE:CLDI) (Profile) is committed to developing a novel approach to treating cancer through the precise delivery of genetic medic

      7/7/25 8:30:00 AM ET
      $CGON
      $CLDI
      $MRK
      $REGN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
      Biotechnology: Pharmaceutical Preparations
    • Vertex Presents Longer-Term Data at the 2025 European Hematology Association (EHA) Congress Demonstrating Durability of CASGEVY® and Provides Update on Expanding Global Access to CASGEVY

      - Data from longer-term follow-up of patients in ongoing clinical trials further demonstrate durability of the clinical benefits of CASGEVY® - - Multiple reimbursement agreements secured, expanding access to CASGEVY to more patients around the world - TORONTO, July 3, 2025 /CNW/ - Vertex Pharmaceuticals (NASDAQ:VRTX) recently announced positive longer-term data for PrCASGEVY® (exagamglogene autotemcel) from global ongoing pivotal clinical trials in people with severe sickle cell disease (SCD) or transfusion-dependent beta thalassemia (TDT). The results, presented at the European Hematology Association (EHA) Congress, continue to demonstrate the durable clinical benefits of CASGEVY. The longe

      7/3/25 9:38:00 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex and Ono Pharmaceutical Announce Strategic Agreement to Develop and Commercialize Povetacicept in Japan and South Korea

      - Exclusive collaboration and license agreement for povetacicept in these countries - - Ono will leverage its deep expertise in clinical development and commercialization for chronic kidney disease in Japan and South Korea to accelerate advancement of povetacicept for patients with IgA nephropathy and primary membranous nephropathy - Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) and Ono Pharmaceutical Co., Ltd. (OTC:OPHLY) today announced an exclusive collaboration and license agreement for the development and commercialization of Vertex's povetacicept in Japan and South Korea. Povetacicept is a recombinant fusion protein therapeutic and dual antagonist of the BAFF (B cell activatin

      6/23/25 4:00:00 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Presents Positive Data for Zimislecel in Type 1 Diabetes at the American Diabetes Association 85th Scientific Sessions

      – Results from the study continue to demonstrate the transformative potential of zimislecel with consistent and durable patient benefit – – All 12 patients with at least one year of follow-up who received a full dose of zimislecel as a single infusion achieved ADA-recommended target HbA1c levels <7% and >70% time-in-range (70-180 mg/dL), and 10/12 patients were insulin free – – Data presented at ADA simultaneously published in the New England Journal of Medicine – – Vertex to host investor webcast tonight, June 20, 2025, at 7:15 p.m. CT / 8:15 p.m. ET – Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) today announced simultaneous presentation and publication of updated data from th

      6/20/25 7:15:00 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Presents New Data on Benefits of ALYFTREK® and Importance of Achieving Lower Sweat Chloride Levels at the European Cystic Fibrosis Conference

      - Oral presentation on outcomes following treatment with CFTR modulators show that improvements in CFTR function, as measured by lower sweat chloride, correlate with better outcomes for people with cystic fibrosis - - Oral presentation on new post hoc data from randomized, controlled and open-label trials suggest improved quality of life results with ALYFTREK compared to TRIKAFTA® – Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) today announced data across multiple studies demonstrating positive clinical and quality of life benefits of treatment with CFTR modulators and, in particular, ALYFTREK® (vanzacaftor/tezacaftor/deutivacaftor), which is approved in the United States and United

      6/6/25 12:00:00 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex to Participate in Upcoming Investor Conferences

      Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) today announced management participation in three upcoming investor conferences. Susie Lisa, Senior Vice President, Investor Relations, and Manisha Pai, Executive Director, Investor Relations, will participate in the Evercore Biotechnology Summit on Wednesday, May 21, 2025. Dr. Reshma Kewalramani, Chief Executive Officer and President, will participate in a fireside chat at the Bernstein 41st Annual Strategic Decisions Conference (SDC) on Friday, May 30, 2025, at 8:00 a.m. ET. Dr. Kewalramani and Dr. David Altshuler, Executive Vice President, Global Research, and Chief Scientific Officer, will participate in a fireside chat at the Gold

      5/15/25 4:05:00 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Reports First Quarter 2025 Financial Results

      — Total revenue of $2.77 billion, a 3% increase compared to Q1 2024; raised the low end of total revenue guidance by $100 million to a new range of $11.85 to $12 billion — — Strong progress with CASGEVY®, ALYFTREK™ and JOURNAVX™ launches — — Povetacicept (pove) IgAN Phase 3 interim analysis (IA) cohort fully enrolled and zimislecel Phase 3 program to complete dosing this quarter, setting up potential filings in 2026; inaxaplin Phase 3 IA cohort on track to complete enrollment in the second half of 2025 — — Four programs already in pivotal development, with pivotal study of pove in primary membranous nephropathy (pMN) to start this year — Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)

      5/5/25 4:01:00 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Researcher, Paul Negulescu Ph.D., Receives the 2025 Canada Gairdner International Award for Pioneering Research and Discovery of Medicines for Cystic Fibrosis

      Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) today announced that Paul Negulescu, Ph.D. Senior Vice President, Vertex has been awarded the 2025 Canada Gairdner International Award "for pioneering research into the cellular and molecular mechanisms underlying the genetic disease cystic fibrosis, leading to the development of transformative drug therapies based on these mechanisms, thereby improving and saving countless lives." Negulescu shares the award with Michael J. Welsh, M.D., University of Iowa. "For more than 20 years, Paul and the team of dedicated Vertex researchers have focused on discovering and developing breakthrough therapies for people living with cystic fibrosis (CF). P

      4/11/25 5:30:00 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    Vertex Pharmaceuticals Incorporated FDA approvals

    Live FDA approvals issued by the Food and Drug Administration and FDA breaking news

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    • January 30, 2025 - FDA Approves Novel Non-Opioid Treatment for Moderate to Severe Acute Pain

      For Immediate Release: January 30, 2025 Today, the U.S. Food and Drug Administration approved Journavx (suzetrigine) 50 milligram oral tablets, a first-in-class non-opioid analgesic, to treat moderate to severe acute pain in adults. Journavx reduces pain by targeting a pain-signaling pathway involving sodium channels in the peripheral nervous system, before pain signals reach the brain.  Journavx is the first dr

      1/30/25 5:46:14 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • December 8, 2023 - FDA Approves First Gene Therapies to Treat Patients with Sickle Cell Disease

      For Immediate Release: December 08, 2023 Today, the U.S. Food and Drug Administration approved two milestone treatments, Casgevy and Lyfgenia, representing the first cell-based gene therapies for the treatment of sickle cell disease (SCD) in patients 12 years and older. Additionally, one of these therapies, Casgevy, is the first FDA-approved treatment to utilize a type of novel genome editing technology, signali

      12/8/23 11:12:21 AM ET
      $BLUE
      $VRTX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
      Biotechnology: Pharmaceutical Preparations
    • FDA Approval for TRIKAFTA (COPACKAGED) issued to VERTEX PHARMS INC

      Submission status for VERTEX PHARMS INC's drug TRIKAFTA (COPACKAGED) (SUPPL-2) with active ingredient ELEXACAFTOR, IVACAFTOR, TEZACAFTOR; IVACAFTOR has changed to 'Approval' on 08/03/2023. Application Category: NDA, Application Number: 217660, Application Classification: Labeling

      8/4/23 4:36:01 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • FDA Approval for TRIKAFTA (COPACKAGED) issued to VERTEX PHARMS INC

      Submission status for VERTEX PHARMS INC's drug TRIKAFTA (COPACKAGED) (SUPPL-11) with active ingredient ELEXACAFTOR, IVACAFTOR, TEZACAFTOR; IVACAFTOR has changed to 'Approval' on 08/03/2023. Application Category: NDA, Application Number: 212273, Application Classification: Labeling

      8/4/23 4:36:00 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • FDA Approval for ORKAMBI issued to VERTEX PHARMS INC

      Submission status for VERTEX PHARMS INC's drug ORKAMBI (SUPPL-5) with active ingredient IVACAFTOR; LUMACAFTOR has changed to 'Approval' on 08/03/2023. Application Category: NDA, Application Number: 211358, Application Classification: Labeling

      8/4/23 4:36:00 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • FDA Approval for SYMDEKO (COPACKAGED) issued to VERTEX PHARMS INC

      Submission status for VERTEX PHARMS INC's drug SYMDEKO (COPACKAGED) (SUPPL-11) with active ingredient IVACAFTOR; IVACAFTOR, TEZACAFTOR has changed to 'Approval' on 08/03/2023. Application Category: NDA, Application Number: 210491, Application Classification: Labeling

      8/4/23 4:36:00 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • FDA Approval for KALYDECO issued to VERTEX PHARMS INC

      Submission status for VERTEX PHARMS INC's drug KALYDECO (SUPPL-17) with active ingredient IVACAFTOR has changed to 'Approval' on 08/03/2023. Application Category: NDA, Application Number: 207925, Application Classification: Labeling

      8/4/23 4:36:00 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • FDA Approval for ORKAMBI issued to VERTEX PHARMS INC

      Submission status for VERTEX PHARMS INC's drug ORKAMBI (SUPPL-17) with active ingredient IVACAFTOR; LUMACAFTOR has changed to 'Approval' on 08/03/2023. Application Category: NDA, Application Number: 206038, Application Classification: Labeling

      8/4/23 4:36:00 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • FDA Approval for KALYDECO issued to VERTEX PHARMS INC

      Submission status for VERTEX PHARMS INC's drug KALYDECO (SUPPL-16) with active ingredient IVACAFTOR has changed to 'Approval' on 05/03/2023. Application Category: NDA, Application Number: 207925, Application Classification: Efficacy

      5/4/23 10:46:05 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • FDA Approval for TRIKAFTA issued to VERTEX PHARMS INC

      Submission status for VERTEX PHARMS INC's drug TRIKAFTA (ORIG-1) with active ingredient ELEXACAFTOR;TEZACAFTOR;IVACAFTOR;IVACAFTOR has changed to 'Approval' on 04/26/2023. Application Category: NDA, Application Number: 217660, Application Classification: Type 3 - New Dosage Form

      4/27/23 10:43:08 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    Vertex Pharmaceuticals Incorporated Financials

    Live finance-specific insights

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    • Vertex to Announce Second Quarter 2025 Financial Results on August 4th

      Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) will report its second quarter 2025 financial results on Monday, August 4, 2025 after the financial markets close. The company will host a conference call and webcast at 4:30 p.m. ET. To access the call, please dial (833) 630-2124 (U.S.) or +1 (412) 317-0651 (International) and reference the "Vertex Pharmaceuticals Second Quarter 2025 Earnings Call." The conference call will be webcast live and a link to the webcast can be accessed through Vertex's website at www.vrtx.com in the "Investors" section. To ensure a timely connection, it is recommended that participants register at least 15 minutes prior to the scheduled webcast. An archived we

      7/8/25 4:00:00 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Reports First Quarter 2025 Financial Results

      — Total revenue of $2.77 billion, a 3% increase compared to Q1 2024; raised the low end of total revenue guidance by $100 million to a new range of $11.85 to $12 billion — — Strong progress with CASGEVY®, ALYFTREK™ and JOURNAVX™ launches — — Povetacicept (pove) IgAN Phase 3 interim analysis (IA) cohort fully enrolled and zimislecel Phase 3 program to complete dosing this quarter, setting up potential filings in 2026; inaxaplin Phase 3 IA cohort on track to complete enrollment in the second half of 2025 — — Four programs already in pivotal development, with pivotal study of pove in primary membranous nephropathy (pMN) to start this year — Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)

      5/5/25 4:01:00 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex to Announce First Quarter 2025 Financial Results on May 5th

      Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) will report its first quarter 2025 financial results on Monday, May 5, 2025 after the financial markets close. The company will host a conference call and webcast at 4:30 p.m. ET. To access the call, please dial (833) 630-2124 (U.S.) or +1 (412) 317-0651 (International) and reference the "Vertex Pharmaceuticals First Quarter 2025 Earnings Call." The conference call will be webcast live and a link to the webcast can be accessed through Vertex's website at www.vrtx.com in the "Investors" section. To ensure a timely connection, it is recommended that participants register at least 15 minutes prior to the scheduled webcast. An archived webcast

      4/7/25 4:05:00 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Reports Fourth Quarter and Full Year 2024 Financial Results

      — Full year product revenue of $11.02 billion, a 12% increase compared to full year 2023 — — Company provides full year 2025 total revenue guidance of $11.75 to $12.0 billion — — ALYFTREK™ approved in the U.S. for patients ages 6+ with cystic fibrosis; JOURNAVX™ approved in the U.S. for moderate-to-severe acute pain — — Diverse late-stage clinical pipeline accelerates with four programs in pivotal development — — Stuart Arbuckle, Chief Operating Officer, announces intent to retire July 1, 2025; as part of planned transition, Charlie Wagner, Chief Financial Officer, to assume additional role of Chief Operating Officer; Duncan McKechnie, SVP and current head of North America Commercia

      2/10/25 4:01:00 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex to Announce Fourth Quarter and Full Year 2024 Financial Results on February 10

      Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) will report its fourth quarter and full year 2024 financial results on Monday, February 10, 2025 after the financial markets close. The company will host a conference call and webcast at 4:30 p.m. ET. To access the call, please dial (833) 630-2124 (U.S.) or +1 (412) 317-0651 (International) and reference the "Vertex Pharmaceuticals Fourth Quarter 2024 Earnings Call." The conference call will be webcast live and a link to the webcast can be accessed through Vertex's website at www.vrtx.com in the "Investors" section. To ensure a timely connection, it is recommended that participants register at least 15 minutes prior to the scheduled webcas

      1/27/25 7:30:00 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Announces Results From Phase 2 Study of Suzetrigine for the Treatment of Painful Lumbosacral Radiculopathy

      – Treatment with the highly selective NaV1.8 pain signal inhibitor suzetrigine met the primary endpoint with a statistically significant and clinically meaningful 2.02 point within-group reduction from baseline in the Numeric Pain Rating Scale (NPRS) – – Placebo arm showed similar within-group reduction in NPRS – – Suzetrigine was generally well tolerated – – Advancement to Phase 3 in painful lumbosacral radiculopathy planned, pending discussions with regulators – – Vertex to host investor call on December 19 at 8:00 a.m. ET – Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) today announced results from its Phase 2 study of suzetrigine, an investigational, oral, highly selective

      12/19/24 6:00:00 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Reports Third Quarter 2024 Financial Results

      — Product revenue of $2.77 billion, a 12% increase compared to Q3 2023 — — Raising full-year product revenue guidance to $10.8 billion to $10.9 billion — — Preparing for two potential near-term launches: vanzacaftor triple in CF and suzetrigine (VX-548) for moderate-to-severe acute pain — — Pipeline progress continuing with three additional programs advancing to Phase 3: suzetrigine in DPN, povetacicept in IgAN and VX-880 in T1D — Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) today reported consolidated financial results for the third quarter ended September 30, 2024, and raised its full-year product revenue guidance to $10.8 billion to $10.9 billion. "The third quarter marked anot

      11/4/24 4:01:00 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex to Announce Third Quarter 2024 Financial Results on November 4th

      Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) will report its third quarter 2024 financial results on Monday, November 4, 2024 after the financial markets close. The company will host a conference call and webcast at 4:30 p.m. ET. To access the call, please dial (833) 630-2124 (U.S.) or +1 (412) 317-0651 (International) and reference the "Vertex Pharmaceuticals Third Quarter 2024 Earnings Call." The conference call will be webcast live and a link to the webcast can be accessed through Vertex's website at www.vrtx.com in the "Investors" section. To ensure a timely connection, it is recommended that participants register at least 15 minutes prior to the scheduled webcast. An archived web

      10/10/24 4:05:00 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Reports Second Quarter 2024 Financial Results

      — Product revenue of $2.65 billion, a 6% increase compared to Q2 2023 — — Company raises full year product revenue guidance to $10.65 to $10.85 billion — — FDA accepted NDA for vanzacaftor triple in CF with Priority Review and PDUFA target action date of January 2, 2025; additionally, MAA submissions validated in EU and U.K. — — FDA accepted NDA for suzetrigine (VX-548) for moderate-to-severe acute pain with Priority Review and PDUFA target action date of January 30, 2025 — — Advancing broad and deep clinical pipeline with multiple milestones expected in H2:24 — Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) today reported consolidated financial results for the second quarter e

      8/1/24 4:01:00 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex to Announce Second Quarter 2024 Financial Results on August 1

      Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) will report its second quarter 2024 financial results on Thursday, August 1, 2024 after the financial markets close. The company will host a conference call and webcast at 4:30 p.m. ET. To access the call, please dial (833) 630-2124 (U.S.) or +1 (412) 317-0651 (International) and reference the "Vertex Pharmaceuticals Second Quarter 2024 Earnings Call." The conference call will be webcast live and a link to the webcast can be accessed through Vertex's website at www.vrtx.com in the "Investors" section. To ensure a timely connection, it is recommended that participants register at least 15 minutes prior to the scheduled webcast. An archived

      7/1/24 4:05:00 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    Vertex Pharmaceuticals Incorporated Leadership Updates

    Live Leadership Updates

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    • Vertex Appoints Nancy Thornberry to its Board of Directors

      Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) today announced that Nancy Thornberry has been appointed to its Board of Directors as an independent director. Ms. Thornberry has more than 35 years of experience in the pharmaceutical and biotech industries, spanning drug discovery, development and commercialization. She founded and served as Chief Executive Officer of Kallyope until 2021 and remains on its Board of Directors and is Chair of Research & Development. Prior to joining Kallyope, Ms. Thornberry spent more than 30 years at Merck & Co., Inc., most recently as Senior Vice President and Global Franchise Head, Diabetes and Endocrinology, with responsibility for discovery and clinical

      12/5/23 4:01:00 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Appoints Michel Lagarde to its Board of Directors

      Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) today announced that Michel Lagarde has been appointed to its Board of Directors as an independent director. Mr. Lagarde is a senior health care and business leader with global expertise, currently serving as Chief Operating Officer and Executive Vice President of Thermo Fisher Scientific Inc. Prior to Thermo Fisher, Mr. Lagarde served as President and Chief Operating Officer of Patheon, a contract manufacturer to the biopharma industry, and as a Managing Director at JLL Partners, a private equity firm investing in health care services. "We are delighted to have Michel join the Vertex Board. His deep experience across numerous segments of

      10/5/23 8:00:00 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Appoints E. Morrey Atkinson, Ph.D., to EVP and Chief Technical Operations Officer, Head of Biopharmaceutical Sciences and Manufacturing Operations

      Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) today announced that E. Morrey Atkinson, Ph.D., has been appointed Executive Vice President, Chief Technical Operations Officer, Head of Biopharmaceutical Sciences and Manufacturing Operations, effective immediately. Dr. Atkinson has served as Senior Vice President of Global Commercial Manufacturing and Supply Chain since July 2020. This new role and function unifies responsibility for small molecule, cell and gene therapies across preclinical, clinical and commercial biopharmaceutical sciences, manufacturing operations and global supply chain. "Over the last three years, Morrey has played a vital role in building out our commercial manufa

      8/29/23 9:00:00 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Appoints Jonathan Biller as Chief Legal Officer

      Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) today announced that Jonathan Biller has been appointed Chief Legal Officer, effective September 19, 2022. Mr. Biller will report directly to Vertex's Chief Executive Officer and President, Reshma Kewalramani, M.D., and join the company's Executive Committee. In this role, Mr. Biller will oversee all of Vertex's global legal and compliance functions. "Jonathan is an outstanding addition to Vertex with his deep legal, industry and business experience, and I am delighted to welcome him to the company," said Dr. Kewalramani. "Jonathan will lead an extraordinarily talented legal and compliance team and support our continued growth as we expand

      9/8/22 9:00:00 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Vertex Appoints Stuart A. Arbuckle as Chief Operating Officer

      Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) today announced that Stuart A. Arbuckle has been appointed as the company's Executive Vice President, Chief Operating Officer (COO), effective immediately. Mr. Arbuckle has served as Vertex's Executive Vice President and Chief Commercial Officer since 2012 and expanded his role to include oversight of operations earlier this year. "This is an exciting time for Vertex, as we continue to expand access to our cystic fibrosis portfolio around the world and prepare to bring forward new therapies with the potential to transform the treatment of multiple serious diseases," said Reshma Kewalramani, M.D., Chief Executive Officer and President of Ver

      8/4/21 8:30:00 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • OXURION NV Appoints Tom Graney, CFA as Chief Executive Officer

      Patrik De Haes M.D. becomes Non-executive Chairman Leuven, BE and Boston, MA, US – May 17, 2021 – 7:30 AM CET – Oxurion NV (Euronext Brussels: OXUR), a biopharmaceutical company developing next generation standard of care ophthalmic therapies, with a clinical stage portfolio in retinal vascular disorders, announces in a planned succession, the promotion of Tom Graney, CFA from Chief Financial Officer (CFO) to Chief Executive Officer (CEO) of the company. He takes over from Dr. Patrik De Haes, who after 14 years as CEO, has decided to move away from day-to-day management of the company to become the Non-executive Chairman of Oxurion. Thomas Clay, the outgoing Chairman of Oxurion, will remain

      5/17/21 1:30:00 AM ET
      $VRTX
      $IRWD
      $GBIO
      $ACIU
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Aquestive Therapeutics Strengthens Board of Directors with Appointments of Julie Krop, M.D., and Marco Taglietti, M.D., and Announces Resignation of Douglas K. Bratton from Board of Directors

      WARREN, N.J., Feb. 09, 2021 (GLOBE NEWSWIRE) -- Aquestive Therapeutics, Inc. (NASDAQ: AQST), a pharmaceutical company focused on developing and commercializing differentiated products that address patients’ unmet needs and solve therapeutic problems, today announced the appointment of Julie Krop, M.D., Chief Medical Officer of Freeline Therapeutics (NASDAQ: FRLN), and Marco Taglietti, M.D., Director, President and Chief Executive Officer of SCYNEXIS (NASDAQ: SCYX), to the Board of Directors of the Company effective February 10, 2021. Aquestive also announced the resignation of Douglas K. Bratton from the Board of Directors after more than 17 years of service. Aquestive’s Board of Directors

      2/9/21 7:30:00 AM ET
      $FRLN
      $AQST
      $AMAG
      $SCYX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
      Biotechnology: Pharmaceutical Preparations
      Major Pharmaceuticals

    Vertex Pharmaceuticals Incorporated Large Ownership Changes

    This live feed shows all institutional transactions in real time.

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    • SEC Form SC 13G/A filed by Vertex Pharmaceuticals Incorporated (Amendment)

      SC 13G/A - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Subject)

      4/10/24 12:14:10 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G/A filed by Vertex Pharmaceuticals Incorporated (Amendment)

      SC 13G/A - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Subject)

      2/13/24 5:17:31 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G/A filed by Vertex Pharmaceuticals Incorporated (Amendment)

      SC 13G/A - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Subject)

      2/9/24 6:19:03 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G/A filed by Vertex Pharmaceuticals Incorporated (Amendment)

      SC 13G/A - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Subject)

      2/9/24 10:05:23 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G filed by Vertex Pharmaceuticals Incorporated

      SC 13G - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Subject)

      2/13/23 2:49:27 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G filed by Vertex Pharmaceuticals Incorporated

      SC 13G - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Subject)

      2/9/23 12:39:51 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G/A filed by Vertex Pharmaceuticals Incorporated (Amendment)

      SC 13G/A - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Subject)

      2/10/22 8:42:48 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G/A filed by Vertex Pharmaceuticals Incorporated (Amendment)

      SC 13G/A - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Subject)

      2/9/22 10:01:28 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G/A filed

      SC 13G/A - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Subject)

      2/10/21 12:00:05 PM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G/A filed

      SC 13G/A - VERTEX PHARMACEUTICALS INC / MA (0000875320) (Subject)

      2/8/21 10:35:30 AM ET
      $VRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care