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    JMP Securities initiated coverage on Prelude Therapeutics with a new price target

    3/13/24 7:41:41 AM ET
    $PRLD
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $PRLD alert in real time by email
    JMP Securities initiated coverage of Prelude Therapeutics with a rating of Mkt Outperform and set a new price target of $7.00
    Get the next $PRLD alert in real time by email

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    Recent Analyst Ratings for
    $PRLD

    DatePrice TargetRatingAnalyst
    9/19/2024$5.00Neutral → Buy
    H.C. Wainwright
    6/20/2024$3.00Equal Weight → Underweight
    Barclays
    3/13/2024$7.00Mkt Outperform
    JMP Securities
    2/20/2024$5.00Buy → Neutral
    H.C. Wainwright
    12/19/2023$10.00 → $4.00Equal-Weight → Underweight
    Morgan Stanley
    11/21/2022$8.00 → $6.00Neutral → Underperform
    BofA Securities
    9/9/2022$19.00 → $11.00Overweight → Equal-Weight
    Morgan Stanley
    7/29/2022$9.00Buy
    Jefferies
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    Prelude Therapeutics Announces Strategic Business Update

    Prelude to prioritize development of mutant selective JAK2V617F JH2 inhibitor and KAT6A selective degrader programs Pausing further clinical development of SMARCA2 selective degrader programs JAK2V617F option agreement with Incyte, as previously announced, includes upfront payment of $35 million, a $25 million equity investment and $100 million if option is exercised Cumulative capital expected to fund planned operations into 2027 based on the Company's preliminary estimates, and potentially into the third quarter of 2028 if Incyte exercises option on JAK2 program Company to release third quarter 2025 financial results and conduct an investor conference call on November 12, 2025 WILMIN

    11/4/25 7:05:00 AM ET
    $PRLD
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    Prelude Therapeutics Announces Exclusive Option Agreement with Incyte to Advance Mutant Selective JAK2V617F JH2 Inhibitors

    Incyte secures an exclusive option to acquire Prelude's mutant selective JAK2V617F JH2 inhibitor program Mutant selective JAK2V617F JH2 inhibitors have disease-modifying potential in treating patients living with myeloproliferative neoplasms (MPNs) Prelude to receive a $35 million upfront payment and $25 million strategic equity investment, $100 million if Incyte were to exercise the option to acquire the program, and up to $775 million in additional potential milestones plus royalties on net salesPrelude will continue to develop all JAK2V617F program assets during the option period; if optioned, Incyte would lead development and commercialization globally WILMINGTON, Del., Nov. 04, 2025

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    Prelude Therapeutics Announces Publication of Abstracts for Presentation at the American Society of Hematology 67th Annual Meeting

    WILMINGTON, Del., Nov. 03, 2025 (GLOBE NEWSWIRE) -- Prelude Therapeutics Incorporated (NASDAQ:PRLD) ("Prelude" or the "Company"), a clinical-stage precision oncology company, today announced the publication of two abstracts with preclinical data on the Company's JAK2V617F mutant selective inhibitors and CALR-targeted degrader antibody conjugates (DACs) discovery program, both accepted for oral presentation at the American Society of Hematology (ASH) 67th Annual Meeting taking place in Orlando, FL December 6-9, 2025. The abstracts can be found on the ASH 2025 website ASH Annual Meeting & Exposition - Hematology.org. "We are excited for the opportunity to share the first-time disclosure of

    11/3/25 9:01:00 AM ET
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    Prelude Therapeutics upgraded by H.C. Wainwright with a new price target

    H.C. Wainwright upgraded Prelude Therapeutics from Neutral to Buy and set a new price target of $5.00

    9/19/24 7:51:24 AM ET
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    Prelude Therapeutics downgraded by Barclays with a new price target

    Barclays downgraded Prelude Therapeutics from Equal Weight to Underweight and set a new price target of $3.00

    6/20/24 7:37:20 AM ET
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    JMP Securities initiated coverage on Prelude Therapeutics with a new price target

    JMP Securities initiated coverage of Prelude Therapeutics with a rating of Mkt Outperform and set a new price target of $7.00

    3/13/24 7:41:41 AM ET
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    Prelude Therapeutics Incorporated filed SEC Form 8-K: Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Leadership Update, Regulation FD Disclosure, Financial Statements and Exhibits

    8-K - Prelude Therapeutics Inc (0001678660) (Filer)

    11/4/25 8:53:18 AM ET
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    Prelude Therapeutics Incorporated filed SEC Form 8-K: Leadership Update, Regulation FD Disclosure

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    10/17/25 7:40:32 AM ET
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    Prelude Therapeutics Incorporated filed SEC Form 8-K: Other Events

    8-K - Prelude Therapeutics Inc (0001678660) (Filer)

    9/19/25 7:41:30 AM ET
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    Chief Chemistry Officer Combs Andrew bought $69,250 worth of shares (100,000 units at $0.69), increasing direct ownership by 26% to 480,123 units (SEC Form 4)

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    CEO Vaddi Krishna bought $467,438 worth of shares (675,000 units at $0.69), increasing direct ownership by 51% to 1,999,296 units (SEC Form 4)

    4 - Prelude Therapeutics Inc (0001678660) (Issuer)

    3/27/25 4:37:44 PM ET
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    CEO Vaddi Krishna bought $14,909 worth of shares (20,416 units at $0.73), increasing direct ownership by 2% to 1,324,296 units (SEC Form 4)

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    SEC Form 3 filed by new insider Dorton Katina

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    10/20/25 4:01:15 PM ET
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    President, CMO Huang Jane converted options into 9,375 shares and covered exercise/tax liability with 3,355 shares, increasing direct ownership by 7% to 86,917 units (SEC Form 4)

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    10/7/25 7:05:37 AM ET
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    President, CMO Huang Jane converted options into 9,375 shares and covered exercise/tax liability with 3,355 shares, increasing direct ownership by 8% to 80,897 units (SEC Form 4)

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    Prelude Therapeutics Announces Appointment of Katina Dorton, J.D., MBA to its Board of Directors

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    Prelude Therapeutics Announces First Quarter 2022 Financial Results and Operations Update

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    5/10/22 8:00:00 AM ET
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    Prelude Therapeutics Reports Full Year 2021 Financial Results

    Significant progress achieved in 2021: Pipeline now includes six internally discovered small molecule compounds targeting clinically validated pathways in cancers with underserved patients Objectives for 2022: Focused on demonstrating proof-of-concept clinical data for lead pipeline compounds and continued advancement of Prelude's diverse precision oncology pipeline Cash runway guidance extended to 2H/2024 WILMINGTON, Del., March 16, 2022 (GLOBE NEWSWIRE) -- Prelude Therapeutics Incorporated (NASDAQ:PRLD), a clinical-stage precision oncology company, today reported its financial results for the fiscal year ended December 31, 2021. "With Prelude's core competencies in cancer biology an

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    Prelude Therapeutics Announces Strategic Business Update

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    11/4/25 7:05:00 AM ET
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    Prelude Therapeutics' SMARCA2 Degrader PRT3789 Demonstrated Promising Initial Clinical Activity and Safety Profile in Phase 1 Trial

    -  Encouraging signs of anti-tumor activity including objective responses observed in patients with SMARCA4-mutated non-small cell lung cancer (NSCLC) and esophageal cancer in early PRT3789 monotherapy dose escalation -  At doses studied to date, PRT3789 was generally well-tolerated with no dose-limiting toxicities or study drug-related serious adverse events -  Company to host investor conference call and webcast on Friday, September 13, 2024 at 12:00 PM EST WILMINGTON, Del., Sept. 13, 2024 (GLOBE NEWSWIRE) -- Prelude Therapeutics Incorporated (NASDAQ:PRLD), a clinical-stage precision oncology company, today announced the first interim clinical

    9/13/24 10:00:00 AM ET
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    Prelude Therapeutics Announces Publication of Abstract for Presentation at the European Society of Medical Oncology (ESMO) Congress 2024

    PRT3789, a novel, highly-selective SMARCA2 degrader in patients with advanced solid tumors with a SMARCA4 mutation oral session presentation: September 13, 2024, 4:00 PM CEST (10:00 AM EST) Prelude will host an investor webcast on September 13, 2024, 6:00 PM CEST, (12:00 PM EST) WILMINGTON, Del., Sept. 09, 2024 (GLOBE NEWSWIRE) -- Prelude Therapeutics Incorporated (NASDAQ:PRLD) ("Prelude" or the "Company"), a clinical-stage precision oncology company, today announced the publication of an abstract regarding PRT3789 at the European Society of Medical Oncology (ESMO) Congress 2024 taking place in Barcelona, Spain September 13-17, 2024. The abstract can be found on the ESMO 2024 website

    9/9/24 7:30:00 AM ET
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    SEC Form SC 13G/A filed by Prelude Therapeutics Incorporated (Amendment)

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    SEC Form SC 13G/A filed by Prelude Therapeutics Incorporated (Amendment)

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    SEC Form SC 13G/A filed by Prelude Therapeutics Incorporated (Amendment)

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