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    Penumbra, Inc. Reports Third Quarter 2025 Financial Results

    11/5/25 4:05:00 PM ET
    $PEN
    Medical/Dental Instruments
    Health Care
    Get the next $PEN alert in real time by email

    ALAMEDA, Calif., Nov. 5, 2025 /PRNewswire/ -- Penumbra, Inc. (NYSE:PEN), the world's leading thrombectomy company, today reported financial results for the third quarter ended September 30, 2025.

    Penumbra, Inc. (PRNewsfoto/Penumbra, Inc.)

    • Revenue of $354.7 million in the third quarter of 2025, an increase of 17.8% or 16.9% in constant currency1, compared to the third quarter of 2024.
    • Total U.S. revenue of $275.0 million in the third quarter of 2025, an increase of 21.5% compared to the third quarter of 2024.
    • U.S. Thrombectomy revenue of $192.0 million in the third quarter of 2025, an increase of 18.5% compared to the third quarter of 2024. U.S. VTE revenue increased 34% compared to the same period a year ago.
    • Income from operations of $48.8 million or operating margin of 13.8% in the third quarter of 2025.
    • Net income of $45.9 million and adjusted EBITDA1 of $66.7 million or net income margin of 12.9% and adjusted EBITDA margin1 of 18.8% in the third quarter of 2025.

    Third Quarter 2025 Financial Results

    Total revenue increased to $354.7 million for the third quarter of 2025 compared to $301.0 million for the third quarter of 2024, an increase of 17.8%, or 16.9% in constant currency1. The United States represented 77.5% of total revenue and international represented 22.5% of total revenue for the third quarter of 2025. Revenue from the U.S. increased 21.5% while revenue from our international regions increased 6.6%, or 3.0% in constant currency1. Revenue from sales of our global thrombectomy products grew to $236.4 million in the third quarter of 2025, an increase of 15.8%, or 15.1% in constant currency1 over the same period a year ago, driven primarily by the sales of our U.S. thrombectomy products which increased by 18.5% over the same period a year ago. Revenue from sales of our global embolization and access products grew to $118.3 million for the third quarter of 2025, an increase of 22.0%, or 20.8% in constant currency1 from the same period a year ago, driven primarily by our U.S. embolization and access products which increased by 29.2% from the same period a year ago.

    Gross profit for the third quarter of 2025 was $240.4 million, or 67.8% of total revenue compared to $200.3 million, or 66.5% of total revenue, for the third quarter of 2024. Gross margin is impacted by product mix, regional mix, and production initiatives to support demand and create future efficiencies. As such, with favorable product mix, improvement in productivity, and by leveraging our fixed costs on higher volume of new product sales during the year, our gross margin may be positively impacted in the future.

    Total operating expenses were $191.6 million, or 54.0% of total revenue for the third quarter of 2025. This compares to total operating expenses of $164.9 million, or 54.8% of total revenue for the third quarter of 2024. R&D expenses were $22.7 million for the third quarter of 2025, compared to $25.2 million for the third quarter of 2024. SG&A expenses were $168.9 million for the third quarter of 2025, compared to $139.7 million for the third quarter of 2024.

    Income from operations was $48.8 million for the third quarter of 2025, compared to income from operations of $35.4 million for the third quarter of 2024.

    1See "Non-GAAP Financial Measures" for important information about our use of non-GAAP measures.

    Updated Full Year 2025 Financial Outlook

    The Company is increasing its guidance for 2025 total revenue to a range of $1 billion, 375 million to $1 billion, 380 million, which represents 15% to 16% growth over 2024 revenue of $1 billion, 195 million. The Company maintains guidance for U.S. Thrombectomy growth of 20% to 21% compared to 2024 levels. The Company also maintains guidance for both gross margin and operating margin for full year 2025.

    Webcast and Conference Call Information

    Penumbra, Inc. will host a conference call to discuss the third quarter 2025 financial results after market close on Wednesday, November 5, 2025 at 4:30 PM Eastern Time. The conference call can be accessed live over the phone by dialing (888) 596-4144 (conference id: 6572573), or the webcast can be accessed on the "Events and Presentations" section under the "Investors" tab of the Company's website at www.penumbrainc.com. The webcast will be available on the Company's website for at least two weeks following the completion of the call.

    About Penumbra

    Penumbra, Inc., the world's leading thrombectomy company, is focused on developing the most innovative technologies for challenging medical conditions such as ischemic stroke, venous thromboembolism such as pulmonary embolism, and acute limb ischemia. Our broad portfolio, which includes computer assisted vacuum thrombectomy (CAVT), centers on removing blood clots from head-to-toe with speed, safety and simplicity. By pioneering these innovations, we support healthcare providers, hospitals and clinics in more than 100 countries, working to improve patient outcomes and quality of life. For more information, visit www.penumbrainc.com and connect on Instagram, LinkedIn, and X.

    Non-GAAP Financial Measures

    In addition to financial measures prepared in accordance with U.S. generally accepted accounting principles ("GAAP"), the Company uses the following non-GAAP financial measures in this press release: a) constant currency, b) non-GAAP operating expenses, non-GAAP income from operations, non-GAAP net income, and non-GAAP diluted earnings per share ("EPS") and c) adjusted EBITDA and adjusted EBITDA margin.

    Constant Currency. The Company's constant currency revenue disclosures estimate the impact of changes in foreign currency rates on the translation of the Company's current period revenue as compared to the applicable comparable period in the prior year. This impact is derived by taking the current local currency revenue and translating it into U.S. dollars based upon the foreign currency exchange rates used to translate the local currency revenue for the applicable comparable period in the prior year, rather than the actual exchange rates in effect during the current period. It does not include any other effect of changes in foreign currency rates on the Company's results or business.

    Non-GAAP operating expenses, non-GAAP income from operations, non-GAAP net income, and non-GAAP diluted EPS. The adjustments to the GAAP financial measures reflect the exclusion of:

    • the effect of the amortization of finite lived intangible assets acquired in connection with the Sixense acquisition over their estimated useful lives;
    • the excess tax benefits associated with share-based compensation arrangements;
    • non-recurring litigation related expenses;
    • non-cash long-lived asset impairment charges related to the impairment of our immersive healthcare asset group; and
    • one-time expenses in connection with the wind down of the immersive healthcare business.

    Adjusted EBITDA and adjusted EBITDA margin. The Company's adjusted EBITDA reflects the exclusion from GAAP net income (loss) of:

    • non-cash operating charges such as stock-based compensation, depreciation and amortization, and impairment charges;
    • non-operating items such as interest income, interest expense, and provision for (benefit from) income taxes;
    • non-recurring litigation related expenses; and
    • one-time expenses in connection with the wind down of the immersive healthcare business.

    Full reconciliation of these non-GAAP measures to the most comparable GAAP measures is set forth in the tables below.

    Our management believes the non-GAAP financial measures disclosed in this press release are useful to investors in assessing the operating performance of our business and provide meaningful comparisons to prior periods and thus a more complete understanding of our business than could be obtained absent this disclosure. Specifically, we consider the change in constant currency revenue as a useful metric as it provides an alternative framework for assessing how our underlying business performed excluding the effect of foreign currency rate fluctuations. We consider non-GAAP operating expenses, non-GAAP income from operations, non-GAAP net income, and non-GAAP diluted EPS useful metrics as they provide an alternative framework for assessing how our underlying business performed excluding non-cash long-lived asset impairment charges related to the impairment of our immersive healthcare asset group, the amortization expense of finite lived intangible assets acquired in connection with the Sixense acquisition, the excess tax benefits associated with share-based compensation arrangements, expenses related to certain litigation matters that we have determined are not a normal or recurring part of our business, including settlement costs and legal fees, and one-time expenses in connection with the wind down of the immersive healthcare business. Further, we consider adjusted EBITDA and adjusted EBITDA margin useful metrics as they provide an alternative framework for assessing how our underlying business performed excluding non-cash operating charges such as stock-based compensation, depreciation and amortization, and impairment charges, non-operating items such as interest income, interest expense, and provision for (benefit from) income taxes, non-recurring litigation related expenses, and one-time expenses in connection with the wind down of the immersive healthcare business.

    The non-GAAP financial measures included in this press release may be different from, and therefore may not be comparable to, similarly titled measures used by other companies. These non-GAAP measures should not be considered in isolation or as alternatives to GAAP measures. We urge investors to review the reconciliation of these non-GAAP financial measures to the comparable GAAP financial measures included in this press release, and not to rely on any single financial measure to evaluate our business.

    Forward-Looking Statements

    Except for historical information, certain statements in this press release are forward-looking in nature and are subject to risks, uncertainties and assumptions about us. Our business and operations are subject to a variety of risks and uncertainties and, consequently, actual results may differ materially from those projected by any forward-looking statements. Factors that could cause actual results to differ from those projected include, but are not limited to: failure to sustain or grow profitability or generate positive cash flows; failure to effectively introduce and market new products; delays in product introductions; significant competition; inability to further penetrate our current customer base, expand our user base and increase the frequency of use of our products by our customers; inability to achieve or maintain satisfactory pricing and margins; manufacturing difficulties; permanent write-downs or write-offs of our inventory or other assets; product defects or failures; unfavorable outcomes in clinical trials; inability to maintain our culture as we grow; fluctuations in foreign currency exchange rates; potential adverse regulatory actions; and the potential impact of any acquisitions, mergers, dispositions, joint ventures or investments we may make. These risks and uncertainties, as well as others, are discussed in greater detail in our filings with the Securities and Exchange Commission ("SEC"), including our Annual Report on Form 10-K for the year ended December 31, 2024 filed with the SEC on February 18, 2025. There may be additional risks of which we are not presently aware or that we currently believe are immaterial which could have an adverse impact on our business. Any forward-looking statements are based on our current expectations, estimates and assumptions regarding future events and are applicable only as of the dates of such statements. We make no commitment to revise or update any forward-looking statements in order to reflect events or circumstances that may change.

    Penumbra, Inc.

    Condensed Consolidated Balance Sheets

    (unaudited)

    (in thousands)







    September 30, 2025



    December 31, 2024

    Assets









    Current assets:









         Cash and cash equivalents



    $                  321,029



    $                  324,404

         Marketable investments



    149,267



    15,727

         Accounts receivable, net



    183,430



    167,668

         Inventories



    432,365



    406,737

         Prepaid expenses and other current assets



    55,429



    36,589

              Total current assets



    1,141,520



    951,125

    Property and equipment, net



    97,730



    62,641

    Operating lease right-of-use assets



    170,715



    177,787

    Finance lease right-of-use assets



    26,790



    28,018

    Intangible assets, net



    6,368



    6,513

    Goodwill



    166,748



    165,826

    Deferred taxes



    94,478



    100,332

    Other non-current assets



    40,020



    40,939

             Total assets



    $               1,744,369



    $               1,533,181

    Liabilities and Stockholders' Equity









    Current liabilities:









         Accounts payable



    $                    29,821



    $                    31,326

         Accrued liabilities



    124,273



    112,429

      Current operating lease liabilities



    13,086



    12,221

      Current finance lease liabilities



    2,423



    2,369

              Total current liabilities



    169,603



    158,345

    Non-current operating lease liabilities



    180,313



    187,068

    Non-current finance lease liabilities



    21,223



    21,731

    Other non-current liabilities



    14,534



    15,106

              Total liabilities



    385,673



    382,250

    Stockholders' equity:









    Common stock



    39



    38

    Additional paid-in capital



    1,165,195



    1,096,732

    Accumulated other comprehensive income (loss)



    3,114



    (5,843)

    Retained earnings



    190,348



    60,004

    Total stockholders' equity



    1,358,696



    1,150,931

    Total liabilities and stockholders' equity



    $               1,744,369



    $               1,533,181

     

    Penumbra, Inc.

    Condensed Consolidated Statements of Operations

    (unaudited)

    (in thousands, except share and per share amounts)







    Three Months Ended September 30,



    Nine Months Ended September 30,





    2025



    2024



    2025



    2024

    Revenue



    $            354,685



    $            301,039



    $         1,018,280



    $            879,097

    Cost of revenue



    114,269



    100,733



    337,971



    334,823

    Gross profit



    240,416



    200,306



    680,309



    544,274

    Operating expenses:

















    Research and development



    22,677



    25,205



    67,972



    74,773

    Sales, general and administrative



    168,901



    139,737



    482,321



    426,052

    Impairment charge



    —



    —



    —



    76,945

    Total operating expenses



    191,578



    164,942



    550,293



    577,770

    Income (loss) from operations



    48,838



    35,364



    130,016



    (33,496)

    Interest and other income, net



    3,487



    4,414



    11,477



    10,026

    Income (loss) before income taxes



    52,325



    39,778



    141,493



    (23,470)

    Provision for (benefit from) income taxes



    6,474



    10,251



    11,149



    (3,799)

    Net income (loss)



    $              45,851



    $              29,527



    $            130,344



    $            (19,671)



















    Net income (loss) per share:

















    Basic



    $                  1.17



    $                  0.76



    $                  3.36



    $                (0.51)

    Diluted



    $                  1.17



    $                  0.75



    $                  3.32



    $                (0.51)

    Weighted average shares outstanding:

















    Basic



    39,078,378



    38,610,805



    38,827,038



    38,706,809

    Diluted



    39,302,239



    39,178,227



    39,250,680



    38,706,809

     

    Penumbra, Inc.

    Reconciliation of GAAP Operating Expenses and GAAP Income (Loss) from Operations to Non-GAAP Operating Expenses and

    Non-GAAP Income from Operations1

    (unaudited)

    (in thousands)







    Three Months Ended September 30,



    Nine Months Ended September 30,





    2025



    2024



    2025



    2024

    GAAP operating expenses



    $            191,578



    $            164,942



    $         550,293



    $         577,770

    GAAP operating expenses includes the effect of the following

    items:

















    Impairment charge2



    —



    —



    —



    76,945

    Non-recurring litigation related expenses



    —



    —



    —



    4,823

    Amortization of finite lived intangible assets acquired



    —



    —



    —



    4,759

    Wind down expenses3



    —



    4,971



    —



    4,971

    Non-GAAP operating expenses



    $            191,578



    $            159,971



    $         550,293



    $         486,272



















    GAAP income (loss) from operations



    $              48,838



    $              35,364



    $         130,016



    $          (33,496)

    GAAP income (loss) from operations includes the effect of the

    following items:

















    Impairment charge2



    —



    —



    —



    76,945

    Non-recurring litigation related expenses



    —



    —



    —



    4,823

    Amortization of finite lived intangible assets acquired



    —



    —



    —



    4,759

    Wind down expenses3



    —



    4,971



    —



    4,971

    Non-GAAP income from operations



    $              48,838



    $              40,335



    $         130,016



    $           58,002











    1See "Non-GAAP Financial Measures" for important information about our use of non-GAAP measures.

    2Represents charges associated with the impairment of the immersive healthcare asset group during the three months ended June 30, 2024.

    3Represents one-time expenses that include severance and other costs related to the wind down of the immersive healthcare business during the three and nine months ended September 30, 2024.

     

    Penumbra, Inc.

    Reconciliation of GAAP Net Income (Loss) and GAAP Diluted EPS to Non-GAAP Net Income and Non-GAAP Diluted EPS1

    (unaudited)

    (in thousands, except share and per share amounts)







    Three Months Ended

    September 30, 2025



    Three Months Ended

    September 30, 2024



    Nine Months Ended

    September 30, 2025



    Nine Months Ended

    September 30, 2024





    Net

    income



    Diluted

    EPS



    Net

    income



    Diluted

    EPS



    Net

    income



    Diluted

    EPS



    Net (loss)

    income



    Diluted

    EPS

    GAAP net income (loss)



    $    45,851



    $       1.17



    $    29,527



    $       0.75



    $  130,344



    $       3.32



    $  (19,671)



    $     (0.51)

    GAAP net income (loss) includes the effect of the

    following items:

































      Impairment charge2



    —



    —



    —



    —



    —



    —



    76,945



    1.96

      Non-recurring litigation related expenses



    —



    —



    —



    —



    —



    —



    4,823



    0.12

      Amortization of finite lived intangible assets

      acquired



    —



    —



    —



    —



    —



    —



    4,759



    0.12

      Wind down expenses3



    —



    —



    4,971



    0.13



    —



    —



    4,971



    0.13

      Tax effects of the non-GAAP adjustments above4



    —



    —



    (1,198)



    (0.03)



    —



    —



    (22,051)



    (0.56)

      Excess tax benefits related to stock compensation

      awards



    (7,754)



    (0.20)



    (85)



    0.00



    (25,889)



    (0.66)



    (491)



    (0.01)

    Non-GAAP net income



    $    38,097



    $       0.97



    $    33,215



    $       0.85



    $  104,455



    $       2.66



    $    49,285



    $       1.25



































    GAAP diluted EPS







    $       1.17







    $       0.75







    $       3.32







    $     (0.51)

    Non-GAAP diluted EPS







    $       0.97







    $       0.85







    $       2.66







    $       1.25



































    Weighted average shares outstanding used to compute:































    GAAP diluted EPS



    39,302,239



    39,178,227



    39,250,680



    38,706,809

    Non-GAAP diluted EPS5



    39,302,239



    39,178,227



    39,250,680



    39,334,133











    1See "Non-GAAP Financial Measures" for important information about our use of non-GAAP measures. 

    2Represents charges associated with the impairment of the immersive healthcare asset group during the three months ended June 30, 2024.

    3Represents one-time expenses that include severance and other costs related to the wind down of the immersive healthcare business during the three and nine months ended September 30, 2024.

    4For the three and nine months ended September 30, 2024, management used a combined federal and state tax rate of 24.10% to compute the tax effects of non-GAAP adjustments.

    5For the purposes of calculating non-GAAP diluted EPS for the nine months ended September 30, 2024, non-GAAP diluted weighted average shares outstanding of 39,334,133 were used as the Company had non-GAAP net income in the period.

     

    Penumbra, Inc.

    Reconciliation of GAAP Net Income (Loss) and GAAP Net Income (Loss) Margin to Adjusted EBITDA and Adjusted EBITDA

    Margin1

    (unaudited)

    (in thousands, except for percentages)







    Three Months Ended September 30,



    Nine Months Ended September 30,





    2025



    2024



    2025



    2024

    GAAP net income (loss)



    $         45,851



    $         29,527



    $       130,344



    $       (19,671)

    Adjustments to GAAP net income (loss):

















    Depreciation and amortization expense



    2,488



    4,148



    13,010



    19,314

    Interest income, net



    (4,022)



    (3,129)



    (10,756)



    (9,333)

    Provision for (benefit from) income taxes



    6,474



    10,251



    11,149



    (3,799)

    Stock-based compensation expense



    15,932



    10,940



    43,951



    34,069

    Impairment charge2



    —



    —



    —



    76,945

    Non-recurring litigation related expenses



    —



    —



    —



    4,823

    Wind down expenses3



    —



    4,971



    —



    4,971

    Adjusted EBITDA



    $         66,723



    $         56,708



    $       187,698



    $       107,319



















    Revenue



    $       354,685



    $       301,039



    $    1,018,280



    $       879,097

    Adjusted EBITDA



    $         66,723



    $         56,708



    $       187,698



    $       107,319

    GAAP net income (loss) margin



    12.9 %



    9.8 %



    12.8 %



    (2.2) %

    Adjusted EBITDA margin



    18.8 %



    18.8 %



    18.4 %



    12.2 %











    1See "Non-GAAP Financial Measures" for important information about our use of non-GAAP measures. 

    2Represents charges associated with the impairment of the immersive healthcare asset group during the three months ended June 30, 2024.

    3Represents one-time expenses that include severance and other costs related to the wind down of the immersive healthcare business during the three and nine months ended September 30, 2024.

     

    Penumbra, Inc.

    Reconciliation of Revenue Growth by Geographic Regions to Constant Currency Revenue Growth1

    (unaudited)

    (in thousands, except for percentages)







    Three Months Ended

    September 30,



    Reported Change



    FX Impact



    Constant Currency Change





    2025



    2024



    $



    %



    $



    $



    %

    United States



    $        275,029



    $        226,326



    $         48,703



    21.5 %



    $                —



    $         48,703



    21.5 %

    International



    79,656



    74,713



    4,943



    6.6 %



    (2,689)



    2,254



    3.0 %

    Total



    $        354,685



    $        301,039



    $         53,646



    17.8 %



    $         (2,689)



    $         50,957



    16.9 %







    Nine Months Ended

    September 30,



    Reported Change



    FX Impact



    Constant Currency Change





    2025



    2024



    $



    %



    $



    $



    %

    United States



    $        792,707



    $        654,150



    $       138,557



    21.2 %



    $                —



    $       138,557



    21.2 %

    International



    225,573



    224,947



    626



    0.3 %



    (3,169)



    (2,543)



    (1.1) %

    Total



    $     1,018,280



    $        879,097



    $       139,183



    15.8 %



    $         (3,169)



    $       136,014



    15.5 %

     

    Penumbra, Inc.

    Reconciliation of Revenue Change by Product Categories to Constant Currency Revenue Growth1

    (unaudited)

    (in thousands, except for percentages)







    Three Months Ended

    September 30,



    Reported Change



     FX Impact



    Constant Currency Change





    2025



    2024



    $



    %



    $



    $



    %

    Thrombectomy



    $        236,422



    $        204,141



    $         32,281



    15.8 %



    $         (1,444)



    $         30,837



    15.1 %

    Embolization and Access



    118,263



    96,898



    21,365



    22.0 %



    (1,245)



    20,120



    20.8 %

    Total



    $        354,685



    $        301,039



    $         53,646



    17.8 %



    $         (2,689)



    $         50,957



    16.9 %







    Nine Months Ended

    September 30,



    Reported Change



     FX Impact



    Constant Currency Change





    2025



    2024



    $



    %



    $



    $



    %

    Thrombectomy



    $        693,222



    $        595,346



    $         97,876



    16.4 %



    $         (1,682)



    $         96,194



    16.2 %

    Embolization and Access



    325,058



    283,751



    41,307



    14.6 %



    (1,487)



    39,820



    14.0 %

    Total



    $     1,018,280



    $        879,097



    $       139,183



    15.8 %



    $         (3,169)



    $       136,014



    15.5 %

     

    Penumbra, Inc.

    Reconciliation of Revenue Change by Product Categories and Geographic Regions to Constant Currency Revenue Growth1

    (unaudited)

    (in thousands, except for percentages)







    Three Months Ended

    September 30,



    Reported Change



     FX Impact



    Constant Currency Change





    2025



    2024



    $



    %



    $



    $



    %

    Thrombectomy





























    United States



    $        191,994



    $        162,051



    $         29,943



    18.5 %



    $                —



    $         29,943



    18.5 %

    International



    44,428



    42,090



    2,338



    5.6 %



    (1,444)



    894



    2.1 %

    Total Thrombectomy



    236,422



    204,141



    32,281



    15.8 %



    (1,444)



    30,837



    15.1 %

    Embolization and Access





























    United States



    83,035



    64,275



    18,760



    29.2 %



    —



    18,760



    29.2 %

    International



    35,228



    32,623



    2,605



    8.0 %



    (1,245)



    1,360



    4.2 %

    Total Embolization and Access



    118,263



    96,898



    21,365



    22.0 %



    (1,245)



    20,120



    20.8 %

    Total



    $        354,685



    $        301,039



    $         53,646



    17.8 %



    $         (2,689)



    $         50,957



    16.9 %







    Nine Months Ended

    September 30,



    Reported Change



     FX Impact



    Constant Currency Change





    2025



    2024



    $



    %



    $



    $



    %

    Thrombectomy





























    United States



    $        568,419



    $        466,064



    $       102,355



    22.0 %



    $                —



    $       102,355



    22.0 %

    International



    124,803



    129,282



    (4,479)



    (3.5) %



    (1,682)



    (6,161)



    (4.8) %

    Total Thrombectomy



    693,222



    595,346



    97,876



    16.4 %



    (1,682)



    96,194



    16.2 %

    Embolization and Access





























    United States



    224,288



    188,086



    36,202



    19.2 %



    —



    36,202



    19.2 %

    International



    100,770



    95,665



    5,105



    5.3 %



    (1,487)



    3,618



    3.8 %

    Total Embolization and Access



    325,058



    283,751



    41,307



    14.6 %



    (1,487)



    39,820



    14.0 %

    Total



    $     1,018,280



    $        879,097



    $       139,183



    15.8 %



    $         (3,169)



    $       136,014



    15.5 %











    1See "Non-GAAP Financial Measures" for important information about our use of non-GAAP measures.

     

    Investor Relations

    Penumbra, Inc.

    [email protected]



    Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/penumbra-inc-reports-third-quarter-2025-financial-results-302605997.html

    SOURCE Penumbra, Inc.

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