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    SEC Form 10-Q filed by Medpace Holdings Inc.

    7/22/25 4:07:17 PM ET
    $MEDP
    Biotechnology: Commercial Physical & Biological Resarch
    Health Care
    Get the next $MEDP alert in real time by email
    medp-20250630
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    Table of Contents

    UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549
    ___________________________________________
    FORM 10-Q
    ___________________________________________
    (Mark One)
    xQUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
    For the quarterly period ended June 30, 2025
    or
    oTRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
    For the transition period from           to          .
    Commission file number: 001-37856
    ___________________________________________
    Medpace Holdings, Inc.
    (Exact name of registrant as specified in its charter)
    ___________________________________________
    Delaware32-0434904
    (State or other jurisdiction of
    incorporation or organization)
    (I.R.S. Employer
    Identification No.)
    5375 Medpace Way, Cincinnati, OH 45227
    (Address of principal executive offices) (Zip Code)
    (513) 579-9911
    (Registrant’s telephone number, including area code)
    Securities registered pursuant to Section 12(b) of the Act:
    Title of each classTrading Symbol(s)Name of each exchange on which registered
    Common Stock $0.01 par valueMEDPNASDAQ Global Select Market
    Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes x No o
    Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files). Yes x No o
    Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer”, “accelerated filer”, “smaller reporting company” and “emerging growth company” in Rule 12b-2 of the Exchange Act.
    Large accelerated filerxAccelerated filero
    Non-accelerated fileroSmaller reporting companyo
    Emerging growth companyo
    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.           o
    Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes o No x
    Indicate the number of shares outstanding of each of the issuer’s classes of Common Stock, as of the latest practicable date.
    ClassNumber of Shares Outstanding
    Common Stock $0.01 par value
    28,093,026 shares outstanding as of July 18, 2025


    Table of Contents
    MEDPACE HOLDINGS, INC. AND SUBSIDIARIES
    FORM 10-Q
    FOR QUARTERLY PERIOD ENDED JUNE 30, 2025
    TABLE OF CONTENTS
    Item NumberPage
    PART I — FINANCIAL INFORMATION
    3
    Item 1.
    Financial Statements (unaudited)
    3
    Condensed Consolidated Balance Sheets as of June 30, 2025 and December 31, 2024
    3
    Condensed Consolidated Statements of Operations for the three and six months ended June 30, 2025 and 2024
    4
    Condensed Consolidated Statements of Comprehensive Income for the three and six months ended June 30, 2025 and 2024
    5
    Condensed Consolidated Statements of Shareholders’ Equity for the three and six months ended June 30, 2025 and 2024
    6
    Condensed Consolidated Statements of Cash Flows for the six months ended June 30, 2025 and 2024
    7
    Notes to Condensed Consolidated Financial Statements
    8
    Item 2.
    Management’s Discussion and Analysis of Financial Condition and Results of Operations
    19
    Item 3.
    Quantitative and Qualitative Disclosures About Market Risk
    26
    Item 4.
    Controls and Procedures
    26
    PART II — OTHER INFORMATION
    27
    Item 1.
    Legal Proceedings
    27
    Item 1A.
    Risk Factors
    27
    Item 2.
    Unregistered Sales of Equity Securities and Use of Proceeds
    27
    Item 3.
    Defaults Upon Senior Securities
    27
    Item 4.
    Mine Safety Disclosures
    28
    Item 5.
    Other Information
    28
    Item 6.
    Exhibits
    28
    EXHIBIT INDEX
    29
    SIGNATURES
    30
    -2-

    Table of Contents
    PART I — FINANCIAL INFORMATION
    Item 1. Financial Statements
    MEDPACE HOLDINGS, INC. AND SUBSIDIARIES
    CONDENSED CONSOLIDATED BALANCE SHEETS (UNAUDITED)
    (Amounts in thousands, except share amounts)
    As of
    June 30,
    2025
    December 31,
    2024
    ASSETS
    Current assets:
    Cash and cash equivalents$46,330 $669,436 
    Accounts receivable and unbilled, net (includes $2.3 million and $4.2 million with related parties at June 30, 2025 and December 31, 2024, respectively)
    377,921 296,443 
    Prepaid expenses and other current assets96,554 63,350 
    Total current assets520,805 1,029,229 
    Property and equipment, net135,481 123,615 
    Operating lease right-of-use assets129,504 128,649 
    Goodwill662,396 662,396 
    Intangible assets, net33,893 34,366 
    Deferred income taxes65,792 100,357 
    Other assets23,802 22,254 
    Total assets$1,571,673 $2,100,866 
    LIABILITIES AND SHAREHOLDERS’ EQUITY
    Current liabilities:
    Accounts payable (includes $0.1 million and $0.2 million with related parties at June 30, 2025 and December 31, 2024, respectively)
    $43,275 $32,528 
    Accrued expenses323,505 307,807 
    Advanced billings (includes $15.1 million and $14.6 million with related parties at June 30, 2025 and December 31, 2024, respectively)
    808,783 710,585 
    Other current liabilities44,880 53,633 
    Total current liabilities1,220,443 1,104,553 
    Operating lease liabilities124,946 126,234 
    Deferred income tax liability2,016 1,800 
    Other long-term liabilities51,917 42,734 
    Total liabilities1,399,322 1,275,321 
    Commitments and contingencies (see Note 11)
    Shareholders’ equity:
    Preferred stock - $0.01 par-value; 5,000,000 shares authorized; no shares issued and outstanding at June 30, 2025 and December 31, 2024
    — — 
    Common stock - $0.01 par-value; 250,000,000 shares authorized at June 30, 2025 and December 31, 2024; 28,088,626 and 30,630,799 shares issued and outstanding at June 30, 2025 and December 31, 2024, respectively
    281 306 
    Treasury stock - 70,073 shares at June 30, 2025 and December 31, 2024
    (12,235)(12,235)
    Additional paid-in capital893,174 844,050 
    (Accumulated deficit) retained earnings(703,215)8,167 
    Accumulated other comprehensive loss(5,654)(14,743)
    Total shareholders’ equity172,351 825,545 
    Total liabilities and shareholders’ equity$1,571,673 $2,100,866 

    See notes to condensed consolidated financial statements.
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    MEDPACE HOLDINGS, INC. AND SUBSIDIARIES
    CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (UNAUDITED)
    (Amounts in thousands, except per share amounts)Three Months Ended
    June 30,
    Six Months Ended
    June 30,
     2025202420252024
    Revenue, net (includes $16.9 million and $11.2 million with related parties for the three months ended June 30, 2025 and 2024, respectively, and $30.7 million and $24.0 million with related parties for the six months ended June 30, 2025 and 2024, respectively)
    $603,311 $528,104 $1,161,881 $1,039,148 
    Operating expenses:
    Direct service costs, excluding depreciation and amortization185,826 171,541 363,642 343,033 
    Reimbursed out-of-pocket expenses237,472 202,725 439,876 387,135 
    Total direct costs423,298 374,266 803,518 730,168 
    Selling, general and administrative46,664 41,453 104,561 85,534 
    Depreciation6,777 6,874 13,471 13,505 
    Amortization237 361 473 722 
    Total operating expenses476,976 422,954 922,023 829,929 
    Income from operations126,335 105,150 239,858 209,219 
    Other (expense) income, net:
    Miscellaneous (expense) income, net(2,875)(133)(4,691)4,460 
    Interest income, net1,078 5,465 7,541 9,585 
    Total other (expense) income, net(1,797)5,332 2,850 14,045 
    Income before income taxes124,538 110,482 242,708 223,264 
    Income tax provision34,278 22,131 37,853 32,322 
    Net income$90,260 $88,351 $204,855 $190,942 
    Net income per share attributable to common shareholders:
    Basic$3.16 $2.85 $6.95 $6.17 
    Diluted$3.10 $2.75 $6.79 $5.96 
    Weighted average common shares outstanding:
    Basic28,60130,99029,48930,917
    Diluted29,14332,08630,16532,046
    See notes to condensed consolidated financial statements.

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    MEDPACE HOLDINGS, INC. AND SUBSIDIARIES
    CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (UNAUDITED)
    (Amounts in thousands)Three Months Ended
    June 30,
    Six Months Ended
    June 30,
    2025202420252024
    Net income$90,260 $88,351 $204,855 $190,942 
    Other comprehensive income (loss)
    Foreign currency translation adjustments, net of taxes5,967 (548)9,089 (2,517)
    Comprehensive income$96,227 $87,803 $213,944 $188,425 
    See notes to condensed consolidated financial statements.
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    MEDPACE HOLDINGS, INC. AND SUBSIDIARIES
    CONDENSED CONSOLIDATED STATEMENTS OF SHAREHOLDERS' EQUITY (UNAUDITED)
    (Amounts in thousands)
    Common Stock
    Treasury Stock
    Additional
    Paid-In
    Capital
    (Accumulated Deficit) Retained Earnings
    Accumulated
    Other
    Comprehensive
    Loss
    Total
    BALANCE — December 31, 2023$308 $(12,322)$802,681 $(221,645)$(10,072)$558,950 
    Net income102,591 102,591 
    Foreign currency translation(1,969)(1,969)
    Stock-based compensation expense4,310 4,310 
    Stock options exercised2 7,658 7,660 
    Re-issuance of treasury stock87 (87)— 
    BALANCE — March 31, 2024$310 $(12,235)$814,649 $(119,141)$(12,041)$671,542 
    Net income88,351 88,351 
    Foreign currency translation(548)(548)
    Stock-based compensation expense3,588 3,588 
    Stock options exercised666 666 
    BALANCE — June 30, 2024$310 $(12,235)$818,903 $(30,790)$(12,589)$763,599 
    Common Stock
    Treasury Stock
    Additional
    Paid-In
    Capital
    (Accumulated Deficit) Retained Earnings
    Accumulated
    Other
    Comprehensive
    Loss
    Total
    BALANCE — December 31, 2024$306 $(12,235)$844,050 $8,167 $(14,743)$825,545 
    Net income114,595 114,595 
    Foreign currency translation3,122 3,122 
    Stock-based compensation expense16,892 16,892 
    Stock options exercised4 25,941 25,945 
    Repurchases of common stock(12)(392,478)(392,490)
    BALANCE — March 31, 2025$298 $(12,235)$886,883 $(269,716)$(11,621)$593,609 
    Net income90,260 90,260 
    Foreign currency translation5,967 5,967 
    Stock-based compensation expense5,951 5,951 
    Stock options exercised340 340 
    Repurchases of common stock(17)(523,759)(523,776)
    BALANCE — June 30, 2025$281 $(12,235)$893,174 $(703,215)$(5,654)$172,351 
    See notes to condensed consolidated financial statements.
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    MEDPACE HOLDINGS, INC. AND SUBSIDIARIES
    CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (UNAUDITED)
    (Amounts in thousands)Six Months Ended
    June 30,
    20252024
    CASH FLOWS FROM OPERATING ACTIVITIES:
    Net income$204,855 $190,942 
    Adjustments to reconcile net income to net cash provided by operating activities:
    Depreciation13,471 13,505 
    Amortization473 722 
    Stock-based compensation expense22,843 7,898 
    Noncash lease expense11,687 11,461 
    Deferred income tax provision (benefit)34,856 (919)
    Other(520)(3,903)
    Changes in assets and liabilities:
    Accounts receivable and unbilled, net(81,980)(2,714)
    Prepaid expenses and other current assets(33,130)(11,251)
    Accounts payable12,021 (2,453)
    Accrued expenses12,249 915 
    Advanced billings98,198 78,557 
    Lease liabilities(12,615)(11,025)
    Other assets and liabilities, net(8,046)(2,661)
    Net cash provided by operating activities274,362 269,074 
    CASH FLOWS FROM INVESTING ACTIVITIES:
    Property and equipment expenditures(16,107)(18,368)
    Other100 8,108 
    Net cash used in investing activities(16,007)(10,260)
    CASH FLOWS FROM FINANCING ACTIVITIES:
    Proceeds from stock option exercises26,285 8,326 
    Repurchases of common stock(912,815)— 
    Net cash (used in) provided by financing activities(886,530)8,326 
    EFFECT OF EXCHANGE RATES ON CASH, CASH EQUIVALENTS, AND
    RESTRICTED CASH
    5,069 (1,695)
    (DECREASE) INCREASE IN CASH, CASH EQUIVALENTS, AND RESTRICTED CASH(623,106)265,445 
    CASH, CASH EQUIVALENTS, AND RESTRICTED CASH — Beginning of period669,436 245,449 
    CASH, CASH EQUIVALENTS, AND RESTRICTED CASH — End of period$46,330 $510,894 
    See notes to condensed consolidated financial statements.
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    MEDPACE HOLDINGS, INC. AND SUBSIDIARIES
    NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED)
    June 30, 2025
    (1) Basis of Presentation
    Description of Business
    Medpace Holdings, Inc. (together with its subsidiaries, “Medpace” or the “Company”), a Delaware corporation, is a global provider of clinical research-based drug and medical device development services. The Company partners with pharmaceutical, biotechnology, and medical device companies in the development and execution of clinical trials. The Company’s drug development services focus on full service Phase I-IV clinical development services and include development plan design, project management, regulatory affairs, clinical monitoring, data management and analysis, pharmacovigilance new drug application submissions, post-marketing clinical support, laboratory services, clinical human pharmacology, imaging services, and electrocardiography reading support for clinical trials.
    The Company’s operations are principally based in North America, Europe, and Asia.
    Unaudited Interim Financial Information
    The interim condensed consolidated financial statements include the accounts of the Company, are prepared in conformity with U.S. generally accepted accounting principles (“GAAP”), and are unaudited. In the opinion of the Company’s management, all adjustments of a normal recurring nature necessary for a fair presentation have been reflected. Certain financial information that is normally included in annual financial statements prepared in accordance with GAAP, but that is not required for interim reporting purposes, has been omitted. The preparation of the interim condensed consolidated financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the interim condensed consolidated financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results and outcomes could differ from management’s estimates and assumptions. As such, the information included in this quarterly report on Form 10-Q should be read in conjunction with the Company’s audited consolidated financial statements and related notes included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2024.
    Share Repurchases
    In 2022, the Company’s Board of Directors (“Board”) approved a stock repurchase program of up to $500.0 million. In the first and second quarters of 2025, the Board approved increases of $600.0 million and $1.0 billion, respectively, to the Company’s stock repurchase program bringing the total repurchase authorization up to $2.1 billion. During the three and six months ended June 30, 2025, the Company repurchased 1,754,264 shares and 2,947,275 shares for $518.5 million and $908.4 million, respectively. The Company did not execute any share repurchases during the three and six months ended June 30, 2024. As of June 30, 2025, the Company has remaining authorization of $826.3 million under the repurchase program.
    Repurchases under the share repurchase program are executed in the open market or negotiated transactions under trading plans put in place pursuant to Rule 10b5-1. The Company constructively retired the repurchased shares associated with these approved share repurchases, except for a small portion which were retained as Treasury Shares on the condensed consolidated statements of shareholders' equity. Retired share repurchase amounts paid in excess of par value are reflected within Accumulated deficit/Retained earnings in the Company’s condensed consolidated balance sheets.
    Recently Issued Accounting Pronouncements
    In December 2023, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”) 2023-09, "Income Taxes (Topic 740): Improvements to Income Tax Disclosures" which requires entities to enhance disclosures around income taxes. The guidance is effective for annual periods beginning after December 15, 2024, with early adoption permitted. The Company is currently evaluating the effect this standard will have on its consolidated financial statements and related disclosures.
    In November 2024, the FASB issued ASU 2024-03, “Income Statement-Reporting Comprehensive Income-Expense Disaggregation Disclosures (Subtopic 220-40): Disaggregation of Income Statement Expenses” to improve disclosures by providing more detailed information about the types of expenses in commonly presented expense captions. The guidance is effective for annual reporting periods beginning after December 15, 2026, and interim periods within fiscal years beginning
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    after December 15, 2027, with early adoption permitted. The Company is currently evaluating the effect this standard will have on its consolidated financial statements and related disclosures.
    (2) Net Income Per Share
    Basic and diluted earnings or loss per share (“EPS”) are computed using the two-class method, which is an earnings allocation that determines EPS for each class of common stock and participating securities according to dividends declared and participation rights in undistributed earnings. The Company’s Restricted Stock Awards (“RSA”) are considered participating securities because they are legally issued at the date of grant and holders are entitled to receive non-forfeitable dividends during the vesting term.
    The computation of diluted EPS includes additional common shares, such as unvested Restricted Stock Units (“RSU”) and stock options with exercise prices less than the average market price of the Company’s common stock during the period (“in-the-money options”), which would be considered outstanding. This assumes that additional shares would have to be issued in cases where the exercise price of stock options is less than the value of the common stock being acquired because the cash proceeds received from the stock option holder would not be sufficient to acquire that same number of shares. The Company does not compute diluted EPS in cases where the inclusion of such additional shares would be anti-dilutive in effect.
    The following table sets forth the computation of basic and diluted earnings per share for the three and six months ended June 30, 2025 and 2024 (in thousands, except for earnings per share):
    Three Months Ended
    June 30,
    Six Months Ended
    June 30,
    2025202420252024
    Weighted-average shares:
    Common shares outstanding28,60130,99029,48930,917
    RSAs— — — 7
    Total weighted-average shares28,60130,99029,48930,924
    Earnings per common share—Basic
    Net income$90,260 $88,351 $204,855 $190,942 
    Less: Undistributed earnings allocated to RSAs— — — (41)
    Net income available to common shareholders—Basic$90,260 $88,351 $204,855 $190,901 
    Net income per common share—Basic$3.16 $2.85 $6.95 $6.17 
    Basic weighted-average common shares outstanding28,60130,99029,48930,917
    Effect of diluted shares5421,0966761,129
    Diluted weighted-average shares outstanding29,14332,08630,16532,046
    Net income per common share—Diluted$3.10 $2.75 $6.79 $5.96 
    During the three and six months ended June 30, 2025, the Company had (in thousands) 205.3 and 198.0 stock options, respectively, that were excluded due to the exercise price exceeding the average fair value of the Company’s common stock during the period. During the six months ended June 30, 2024, the Company had (in thousands) 4.8 stock options that were excluded due to the exercise price exceeding the average fair value of the Company’s common stock during the period.
    (3) Fair Value Measurements
    The Company follows accounting guidance related to fair value measurements that defines fair value, establishes a framework for measuring fair value, and establishes a hierarchy for inputs used in measuring fair value. This hierarchy
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    maximizes the use of “observable” inputs and minimizes the use of unobservable inputs by requiring that the most observable inputs be used when available. The hierarchy specifies three levels based on the inputs, as follows:
    Level 1: Valuations based on quoted prices in active markets for identical assets or liabilities.
    Level 2: Valuations based on directly observable inputs or unobservable inputs corroborated by market data.
    Level 3: Valuations based on unobservable inputs supported by little or no market activity representing management’s determination of assumptions of how market participants would price the assets or liabilities.
    The fair value of financial instruments such as cash and cash equivalents, accounts receivable and unbilled, net, accounts payable, accrued expenses and advanced billings approximate their carrying amounts due to their short term maturities.
    The Company does not have material recurring fair value measurements as of June 30, 2025 and December 31, 2024. There were no material transfers between Level 1, Level 2 or Level 3 during the three and six months ended June 30, 2025 and 2024.
    (4) Contract Assets and Contract Liabilities
    Contract assets and liabilities are reflected in the Company’s condensed consolidated balance sheets within the accounts reflected below.
    Contract Assets
    Accounts receivable represent amounts due from the Company’s customers who are concentrated primarily in the pharmaceutical, biotechnology, and medical device industries. Unbilled represents revenue recognized to date that has not been billed or is not yet contractually billable to the customer. In general, amounts become billable upon the achievement of negotiated contractual events, in accordance with predetermined payment schedules or when a reimbursable expense has been incurred. Amounts classified to unbilled are those billable to customers within one year from the respective balance sheet date.
    Accounts receivable and unbilled, net consisted of the following (in thousands):
    As of
    June 30,
    2025
    December 31,
    2024
    Accounts receivable$371,918 $291,096 
    Unbilled receivables6,003 5,347 
    Less: allowance for doubtful accounts— — 
    Total accounts receivable and unbilled, net$377,921 $296,443 
    Contract Liabilities
    Advanced billings represent cash received from customers, or billed amounts per an agreed upon payment schedule, in advance of services being performed or revenue being recognized.
    Advanced billings consisted of the following (in thousands):
    As of
    June 30,
    2025
    December 31,
    2024
    Advanced billings$808,783 $710,585 
    As of June 30, 2025 and December 31, 2024, the Company had approximately $3.5 billion of performance obligations remaining to be performed for active projects.
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    (5) Intangible Assets, Net
    Intangible assets, net consisted of the following (in thousands):
    As of
    June 30,
    2025
    December 31,
    2024
    Intangible assets:
    Finite-lived intangible assets:
    Carrying amount:
    Customer relationships$145,051 $145,051 
    Accumulated amortization:
    Customer relationships(142,804)(142,331)
    Total finite-lived intangible assets, net2,247 2,720 
    Trade name (indefinite-lived)31,646 31,646 
    Total intangible assets, net$33,893 $34,366 
    As of June 30, 2025, estimated amortization expense of the Company’s intangible assets for each of the remaining years is as follows (in thousands):
    Amortization
    Remainder of 2025
    $473 
    2026620 
    2027577 
    2028577 
    $2,247 
    (6) Accrued Expenses
    Accrued expenses consisted of the following (in thousands):
    As of
    June 30,
    2025
    December 31,
    2024
    Employee compensation and benefits$68,238 $84,929 
    Project related reimbursable expenses244,354 212,008 
    Other10,913 10,870 
    Total accrued expenses$323,505 $307,807 
    (7) Debt
    On September 30, 2019 (the “Closing Date”), the Company obtained an unsecured credit facility (as amended from time to time, the “Credit Facility”) through its wholly owned subsidiaries, Medpace, Inc., as borrower (the “Borrower”), and Medpace IntermediateCo, Inc., as guarantor (the “Guarantor”).
    On the Closing Date, the Borrower and lender entered into a Loan Agreement (as it may be amended from time to time, the “Loan Agreement”) providing for the Credit Facility, and the Guarantor executed a Guaranty Agreement providing for its guarantee of the payment and performance of the obligations under the Loan Agreement. On March 28, 2024, the Company entered into Amendment No. 6 to the Loan Agreement, which changed the aggregate principal amount that may be borrowed under the Credit Facility to up to $10.0 million and extended the expiration date of revolving credit note to March 31, 2025. On March 28, 2025, the Company entered into Amendment No. 7 to the Loan Agreement, which extended the expiration date of the revolving credit note to March 31, 2026. On April 18, 2025, the Company entered into Amendment No. 8 to the Loan Agreement, which increased the aggregate principal amount that may be borrowed under the
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    Credit Facility to up to $600.0 million, adjusted the interest rate charged on the Credit Facility and extended the expiration date of the revolving credit note to April 30, 2027. The Credit Facility bears interest at a rate of the sum of The Secured Overnight Financing Rate (SOFR) plus 100 basis points (1.00%) or the highest of the Prime Rate, the sum of the Overnight Bank Funding Rate plus 50 basis points (0.50%) and the sum of Daily Simple SOFR plus 100 basis points (1.00%). As of June 30, 2025 and December 31, 2024, the Company had no indebtedness under the Credit Facility.
    On July 17, 2025, the Company entered into Amendment No. 9 to the Loan Agreement, which decreased the aggregate principal amount that may be borrowed under the Credit Facility to up to $10.0 million.
    The Loan Agreement contains other customary loan terms, representations and warranties, and affirmative and negative covenants, in each case, subject to customary limitations, exceptions and exclusions. The Loan Agreement contains certain events of default, including, among others, non-payment of principal or interest and breach of the covenants.
    (8) Leases
    The Company enters into leases for real estate and equipment. Real estate leases are for our corporate office space and laboratories around the world. Real estate leases have remaining lease terms of less than 1 year to 15 years. Many of the Company’s leases include options to extend the leases on a month to month basis or for set periods for up to 20 years. Many leases also include options to terminate the leases within 1 year or per other contractual terms.
    The components of lease expense were as follows (in thousands):
    Three Months Ended June 30,Six Months Ended June 30,
    2025202420252024
    Operating lease cost$7,688 $7,903 $15,753 $15,768 
    Variable lease cost2,819 2,735 5,831 5,401 
    Supplemental cash flow information related to the leases was as follows (in thousands):
    Six Months Ended June 30,
    20252024
    Cash paid for amounts included in the measurement of lease liabilities:
    Operating cash flows from operating leases$13,023 $11,565 
    Right-of-use assets obtained in exchange for lease obligations:
    Operating leases8,202 2,222 
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    Supplemental balance sheet information related to the leases was as follows (in thousands):
    As of
    June 30,
    2025
    December 31,
    2024
    Operating lease right-of-use assets - related parties$71,333 $74,889 
    Operating lease right-of-use assets - non-related parties58,171 53,760 
    Operating lease right-of-use assets$129,504 $128,649 
    Other current liabilities - related parties6,606 6,310 
    Other current liabilities - non-related parties18,280 16,979 
    Other current liabilities$24,886 $23,289 
    Operating lease liabilities - related parties80,857 84,259 
    Operating lease liabilities - non-related parties44,089 41,975 
    Operating lease liabilities124,946 126,234 
    Total operating lease liabilities$149,832 $149,523 
    Weighted Average Remaining Lease Term (years)
    Operating leases9.19.6
    Weighted Average Discount Rate
    Operating leases5.6 %5.7 %
    Lease payments due related to lease liabilities as of June 30, 2025 were as follows (in thousands):
    Related Party
    Operating Leases
    Non-Related Parties
    Operating Leases
    Total
    Operating Leases
    Remainder of 2025
    $5,827 $10,147 $15,974 
    202611,807 18,758 30,565 
    202710,839 15,328 26,167 
    20288,609 9,981 18,590 
    20298,824 6,976 15,800 
    Later years82,845 7,963 90,808 
    Total lease payments128,751 69,153 197,904 
    Less: imputed interest(41,288)(6,784)(48,072)
    Total$87,463 $62,369 $149,832 
    (9) Shareholder’s Equity and Stock-Based Compensation
    The Company granted 154,264 awards to employees under the 2016 Incentive Award Plan during the six months ended June 30, 2025, consisting of 34,331 RSU and 35,473 stock options having five year vesting schedules and 84,460 stock option awards that vested upon issuance. The Company granted an additional 7,344 stock option awards to non-employee directors under the 2016 Incentive Award Plan during the six months ended June 30, 2025. These awards are scheduled to vest on the earlier of (a) the day immediately preceding the date of the first annual meeting following the date of grant and (b) the first anniversary of the date of grant, subject to the non-employee director continuing in service through the applicable vesting date.
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    Award Activity
    The following table sets forth the Company’s stock option activity:
    Six Months Ended June 30, 2025
    Stock Options Weighted Average
    Exercise Price
    Outstanding - beginning of period1,143,368$130.33 
    Granted127,277$324.56 
    Exercised(404,263)$65.02 
    Cancelled/Forfeited/Expired(8,550)$215.92 
    Outstanding - end of period857,832$189.07 
    Exercisable - end of period500,766$187.29 
    The following table sets forth the Company’s RSA/RSU activity:
    Six Months Ended
    June 30, 2025
    Shares/Units
    Outstanding and unvested - beginning of period365,492
    Granted34,331
    Vested(839)
    Forfeited(13,374)
    Outstanding and unvested - end of period385,610
    Stock-based compensation expense recognized in the condensed consolidated statements of operations related to all outstanding stock-based compensation awards is summarized below (in thousands):
    Three Months Ended June 30,Six Months Ended June 30,
    2025202420252024
    Total direct costs$3,420 $2,308 $6,447 $4,778 
    Selling, general and administrative2,531 1,280 16,396 3,120 
    Total stock-based compensation expense$5,951 $3,588 $22,843 $7,898 
    (10) Income Taxes
    The Company’s effective income tax rate was 27.5% and 20.0% for the three months ended June 30, 2025 and 2024, respectively. The Company's effective income tax rate was 15.6% and 14.5% for the six months ended June 30, 2025 and 2024, respectively. The Company’s effective income tax rate for the three months ended June 30, 2025 varied from the U.S. statutory rate of 21% primarily due to the impact of the state taxes and a decrease in the estimated tax benefits related to Foreign Derived Intangible Income (“FDII”). The Company’s effective income tax rate for the six months ended June 30, 2025 varied from the U.S. statutory rate of 21% due to the impact of state taxes, which was favorably offset by excess tax benefits recognized from share-based compensation.
    On July 4, 2025, the One Big Beautiful Bill Act (“OBBBA”) was enacted in the U.S. The OBBBA includes significant provisions, such as the permanent extension of certain expiring provisions of the Tax Cuts and Jobs Act, modifications to the international tax framework and the restoration of favorable tax treatment for certain business provisions. We are currently assessing its impact on our condensed consolidated financial statements.
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    (11) Commitments and Contingencies
    Legal Proceedings
    The Company is involved in legal proceedings from time to time in the ordinary course of its business, including employment claims and claims related to other business transactions. The Company cannot predict with certainty the outcome of such proceedings, but it believes that adequate reserves have been recorded and losses already recognized with respect to such proceedings, which were immaterial as of June 30, 2025 and December 31, 2024. There is a reasonable possibility that a loss exceeding amounts already recognized may be incurred related to these actions; however, the Company believes that such potential losses were immaterial as of June 30, 2025.
    Purchase Commitments
    The Company has several minimum purchase commitments for project related supplies totaling $18.0 million as of June 30, 2025. In return for the commitment, Medpace receives preferential pricing. The commitments expire at various times through 2029.
    (12) Related Party Transactions
    Employee Loans
    The Company periodically extends short term loans or advances to employees, typically upon commencement of employment. Total receivables as a result of these employee advances of $0.4 million and $0.3 million at June 30, 2025 and December 31, 2024, respectively, are included in the Prepaid expenses and other current assets and Other assets line items of the condensed consolidated balance sheets, respectively, depending on the contractual repayment date.
    Service Agreement
    LIB Therapeutics LLC and subsidiaries (“LIB”)
    Certain executives and employees of the Company, including the chief executive officer, are members of LIB’s board of managers. The Company entered into a MSA dated November 24, 2015 with LIB, a company that engages in research, development, marketing and commercialization of pharmaceutical drugs. Subsequently, the Company and LIB have entered into several task orders for the Company to perform clinical trial related services. The Company recognized total revenue from LIB of $1.7 million and $3.9 million during the three months ended June 30, 2025 and 2024, respectively, and $3.9 million and $10.4 million during the six months ended June 30, 2025 and 2024, respectively, in the Company’s condensed consolidated statements of operations. As of June 30, 2025 and December 31, 2024, the Company had Advanced billings from LIB of $9.1 million and $9.5 million, respectively, in the condensed consolidated balance sheets. In addition, as of June 30, 2025 and December 31, 2024 the Company had Accounts receivable and unbilled, net from LIB of $1.3 million and $2.8 million, respectively, in the condensed consolidated balance sheets.
    CinRX Pharma, subsidiaries and affiliates (“CinRx”)
    Certain executives and employees of the Company, including the chief executive officer, are members of CinRx’s board of managers and/or have equity investments in CinRx, a biotech company. The Company and CinRx have entered into several task orders for the Company to perform clinical trial related services. The Company recognized total revenue from CinRx of $15.1 million and $7.3 million during the three months ended June 30, 2025 and 2024, respectively, and $26.8 million and $13.6 million during the six months ended June 30, 2025 and 2024, respectively, in the Company’s condensed consolidated statements of operations. As of June 30, 2025 and December 31, 2024, the Company had Advanced billings from CinRx of $6.0 million and $5.2 million, respectively, in the condensed consolidated balance sheets. As of June 30, 2025 and December 31, 2024 the Company had Accounts receivable and unbilled, net from CinRx of $1.1 million and $1.4 million, respectively, in the condensed consolidated balance sheets.
    The Summit Hotel (“The Summit”)
    The Summit Hotel, located on the Medpace campus, is owned by the chief executive officer, and managed by an unrelated hospitality management entity. Medpace incurs travel lodging and meeting expenses at The Summit. Medpace incurred expenses of $0.1 million during the three months ended June 30, 2025 and 2024, and $0.1 million and $0.2 million during the six months ended June 30, 2025 and 2024, respectively, at The Summit.
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    Leased Real Estate
    Campus Headquarters Leases
    The Company entered into an operating lease for the occupancy of office space in a building in Cincinnati, Ohio with an entity that is wholly owned by the chief executive officer of the Company. The Company has evaluated its relationship with the related party and concluded that the related party is not a variable interest entity because the Company has no direct ownership interest or relationship other than the lease. The lease was renewed in the first quarter of fiscal year 2023 for a term of ten years through December 2032 with a renewal option for one 10-year term at prevailing market rates. The Company pays rent, taxes, insurance, and maintenance expenses that arise from the use of the property. Annual base rent for its corporate headquarters allows for adjustments to the rental rate annually for increases in the consumer price index. The Company has determined that the lease is an operating lease. Operating lease cost recognized for the three months ended June 30, 2025 and 2024 was $0.7 million. Operating lease cost recognized for the six months ended June 30, 2025 and 2024 was $1.4 million. The operating lease cost was allocated between Total direct costs and Selling, general and administrative in the condensed consolidated statements of operations. The Operating lease right-of-use assets at June 30, 2025 and December 31, 2024 were $16.7 million and $17.6 million, respectively, in the condensed consolidated balance sheets. The current and long-term portions of the lease liabilities at June 30, 2025 were $1.7 million and $15.6 million, respectively, and were recognized in Other current liabilities and Operating lease liabilities in the condensed consolidated balance sheets. The current and long-term portions of the lease liabilities at December 31, 2024 were $1.6 million and $16.5 million, respectively, and were recognized in Other current liabilities and Operating lease liabilities in the condensed consolidated balance sheets.
    In 2018, Medpace, Inc. entered into a multi-year lease agreement governing future occupancy of additional office space in Cincinnati, Ohio with an entity that is wholly owned by the Company’s chief executive officer and certain members of his immediate family. The Company began to occupy the premises in the second quarter of fiscal year 2020. The lease expires in 2040 and the Company has two 10-year options to extend the term of the lease. The Company pays rent, taxes, insurance, and maintenance expenses that arise from the use of the property. Annual base rent for the corporate headquarters allows for adjustments to the rental rate annually for increases in the consumer price index. The Company has determined that the lease is an operating lease. Operating lease cost recognized for the three months ended June 30, 2025 and 2024 was $1.4 million. Operating lease cost recognized for the six months ended June 30, 2025 and 2024 was $2.8 million. The operating lease cost was allocated between Total direct costs and Selling, general and administrative in the condensed consolidated statements of operations. The Operating lease right-of-use assets at June 30, 2025 and December 31, 2024 were $49.3 million and $50.2 million, respectively, in the condensed consolidated balance sheets. The current and long-term portions of the lease liabilities at June 30, 2025 were $1.6 million and $61.1 million, respectively, and were recognized in Other current liabilities and Operating lease liabilities in the condensed consolidated balance sheets. The current and long-term portions of the lease liabilities at December 31, 2024 were $1.5 million and $62.0 million, respectively and were recognized in Other current liabilities and Operating lease liabilities in the condensed consolidated balance sheets.
    The Company entered into a multi-year lease agreement governing the occupancy of office space in a building in Cincinnati, Ohio with an entity that is wholly owned by the Company’s chief executive officer and certain members of his immediate family. The Company assumed occupancy in 2012 and the lease expires in 2027 with the Company having one 10-year option to extend the lease term. The Company pays rent, taxes, insurance, and maintenance expenses that arise from the use of the property. Annual base rent for the corporate headquarters allows for adjustments to the rental rate annually for increases in the consumer price index. The Company has determined that the lease is an operating lease. Operating lease cost recognized for the three months ended June 30, 2025 and 2024 was $0.7 million. Operating lease cost recognized for the six months ended June 30, 2025 and 2024 was $1.3 million. The operating lease cost was allocated between Total direct costs and Selling, general and administrative in the condensed consolidated statements of operations. The Operating lease right-of-use assets at June 30, 2025 and December 31, 2024 were $5.3 million and $6.4 million, respectively, in the condensed consolidated balance sheets. The current and long-term portions of the lease liabilities at June 30, 2025 were $2.3 million and $3.1 million, respectively, and were recognized in Other current liabilities and Operating lease liabilities in the condensed consolidated balance sheets. The current and long-term portions of the lease liabilities at December 31, 2024 were $2.2 million and $4.2 million, respectively, and were recognized in Other current liabilities and Operating lease liabilities in the condensed consolidated balance sheets.
    The Company entered into a multi-year lease agreement governing the occupancy of office space in a building in Cincinnati, Ohio with an entity that is wholly owned by the Company’s chief executive officer and certain members of his immediate family. The Company assumed occupancy in 2012 and the lease expires in 2027 with the Company having one 10-year option to extend the lease term. In the first quarter of 2024, the Company reduced the lease term in connection with
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    a plan to replace the leased office beginning in early 2025. The Company pays rent, taxes, insurance, and maintenance expenses that arise from the use of the property. Annual base rent for the corporate headquarters allows for adjustments to the rental rate annually for increases in the consumer price index. The Company has determined that the lease is an operating lease. Operating lease cost recognized for the three months ended June 30, 2025 and 2024 was less than $0.1 million and $0.8 million, respectively. Operating lease cost recognized for the six months ended June 30, 2025 and 2024 was $0.7 million and $1.5 million, respectively. The operating lease cost was allocated between Total direct costs and Selling, general and administrative in the condensed consolidated statements of operations. The Operating lease right-of-use assets at June 30, 2025 and December 31, 2024 were $0.0 million and $0.7 million, respectively, in the condensed consolidated balance sheets. The current and long-term portions of the lease liabilities at June 30, 2025 were $1.0 million and $1.0 million, respectively, and were recognized in Other current liabilities and Operating lease liabilities in the condensed consolidated balance sheets. The current and long-term portions of the lease liabilities at December 31, 2024 were $0.9 million and $1.5 million, respectively, and were recognized in Other current liabilities and Operating lease liabilities in the condensed consolidated balance sheets.
    Travel Services
    The Company incurs expenses for travel services for company executives provided by private aviation charter companies which is a company controlled by the chief executive officer of the Company (each a “private aviation charter”). The Company may contract directly with the private aviation charter for the use of its aircraft or indirectly through a third party aircraft management and jet charter company (the “Aircraft Management Company”). The travel services provided are primarily for business purposes, with certain personal travel paid for as part of the executives’ compensation arrangements. The Aircraft Management Company also makes the private aviation charter aircraft available to third parties. The Company incurred travel expenses of $0.5 million and $0.7 million during the three months ended June 30, 2025 and 2024, respectively, and $0.9 million and $1.0 million during the six months ended June 30, 2025 and 2024, respectively, related to these travel services. These travel expenses are recorded in Selling, general and administrative in the Company’s condensed consolidated statements of operations. As of June 30, 2025 and December 31, 2024, the Company had Accounts payable to the Aircraft Management Company of $0.1 million and $0.2 million, respectively, in the condensed consolidated balance sheets.
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    (13) Segment Disclosures
    Information about the reportable segment, significant segment expenses and a reconciliation to condensed consolidated net income is as follows (in thousands):
    Three Months Ended
    June 30,
    Six Months Ended
    June 30,
    2025202420252024
    Revenue, net$603,311 $528,104 $1,161,881 $1,039,148 
    Operating expenses:
    Direct service costs, excluding depreciation and amortization - Employee compensation147,942 135,923 291,869 274,444 
    Direct service costs, excluding depreciation and amortization - Other segment items (a)37,884 35,618 71,773 68,589 
    Reimbursed out-of-pocket expenses237,472 202,725 439,876 387,135 
    Total direct costs423,298 374,266 803,518 730,168 
    Selling, general and administrative46,664 41,453 104,561 85,534 
    Depreciation6,777 6,874 13,471 13,505 
    Amortization237 361 473 722 
    Total operating expenses476,976 422,954 922,023 829,929 
    Income from operations126,335 105,150 239,858 209,219 
    Other (expense) income, net:
    Miscellaneous (expense) income, net(2,875)(133)(4,691)4,460 
    Interest income, net1,078 5,465 7,541 9,585 
    Total other (expense) income, net(1,797)5,332 2,850 14,045 
    Income before income taxes124,538 110,482 242,708 223,264 
    Income tax provision34,278 22,131 37,853 32,322 
    Segment net income$90,260 $88,351 $204,855 $190,942 
    Reconciliation of profit or loss
    Adjustments and reconciling items— — — — 
    Condensed consolidated net income$90,260 $88,351 $204,855 $190,942 
    (a) Direct service costs, excluding depreciation and amortization - Other segment items includes costs related to inventory, leases, project subcontractors and other direct service costs.
    Revenue by Category
    The following table disaggregates the Company’s revenue by major source (in thousands):
    Three Months Ended
    June 30,
    Six Months Ended
    June 30,
    2025202420252024
    Therapeutic Area
    Oncology$188,558 $162,952 $359,034 $318,150 
    Metabolic147,873 106,302 295,888 209,941 
    Other118,062 112,432 213,898 220,832 
    Cardiology58,584 60,699 116,863 116,336 
    Central Nervous System61,129 46,519 116,030 90,655 
    AVAI29,105 39,200 60,168 83,234 
    Total revenue$603,311 $528,104 $1,161,881 $1,039,148 
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    Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations
    You should read the following discussion and analysis of our financial condition and results of operations in conjunction with our condensed consolidated financial statements and the notes thereto included elsewhere in this Quarterly Report on Form 10-Q, with our audited consolidated financial statements and the notes thereto included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2024 and with the information under the heading “Management Discussion and Analysis of Financial Condition and Results of Operations” in our Annual Report on Form 10-K for the fiscal year ended December 31, 2024. This item and the related discussion contain forward-looking statements reflecting current expectations that involve risks and uncertainties. Actual results and the timing of events may differ materially from those indicated in such forward-looking statements. Factors that may cause such differences include, but are not limited to, those discussed under the “Forward-Looking Statements” below and “Risk Factors” in “Item 1A Risk Factors” of Part I of our Annual Report on Form 10-K for the fiscal year ended December 31, 2024.
    Forward-Looking Statements
    This Quarterly Report on Form 10-Q contains forward-looking statements. We intend such forward-looking statements to be covered by the safe harbor provisions for forward-looking statements contained in Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. All statements other than statements of historical facts contained herein, are forward looking statements. Forward looking statements include, without limitation, statements regarding our results of operations; financial position and performance; liquidity and our ability to fund our business operations and initiatives; capital expenditure and debt service obligations; business strategies, plans and goals, including those related to marketing, acquisitions and expansion of our business; product approvals and plans; industry trends; general economic conditions, including inflation, interest rates and other pricing pressures that could impact our operating margins; expectations regarding consumer behaviors and trends; our culture and operating philosophy; human resource management; arrangements with and delivery of our services to the customers; conversion of backlog; dividend policy; legal proceedings; and our objectives for future operations. The words “expect,” “anticipate,” “intend,” “plan,” “believe,” “seek,” “see,” “will,” “would,” “target,” “likely,” “opportunity,” “may,” “could,” “outlook,” “can,” “trend,” “might,” “drives,” “hope,” “potential,” “project,” “predict,” and similar expressions are intended to identify forward-looking statements. However, the absence of these words does not mean that a statement is not forward-looking. Forward-looking statements are based largely on our current expectations and projections about future events and financial or other trends that we believe may affect our financial condition, results of operations, business strategy, short-term and long-term business operations and objectives, and financial needs. Any forward-looking statement speaks only as of the date it is made. These forward-looking statements are subject to inherent uncertainties, risks, changes in circumstances and other factors that are difficult to predict. Moreover, we operate in a very competitive and rapidly changing environment in which new risks emerge from time to time. It is not possible for our management to predict all risks, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of such factors, may cause actual results to differ materially from those contained in any forward-looking statements we may make. In light of these risks, uncertainties and assumptions, the forward-looking events and circumstances discussed may not occur and our financial condition and actual results could differ materially and adversely from those anticipated or implied in the forward-looking statements. In other words, these statements are not guarantees of future performance and inherently involve a wide range of risks and uncertainties that are difficult to predict. We caution you therefore against relying on these forward-looking statements. Some of the factors that could cause actual results to differ from our expectations include regional, national, or global political, economic, business, competitive, market and regulatory conditions and the other factors included in our Annual Report on Form 10-K for the fiscal year ended December 31, 2024 in “Item 1A Risk Factors,” “Item 7 Management’s Discussion and Analysis of Financial Condition and Results of Operations,” and “Item 7A Quantitative and Qualitative Disclosures About Market Risk.”
    We qualify all of our forward-looking statements by these cautionary statements. Except as required by applicable law, we do not plan to publicly update or revise any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances or otherwise. For a further discussion of the risks relating to our business, see “Item 1A Risk Factors” of our Annual Report on Form 10-K for the fiscal year ended December 31, 2024 and “Part II – Other Information, Item 1A Risk Factors” herein.
    Business Overview
    We are one of the world’s leading clinical contract research organizations, or CROs, by revenue, solely focused on providing scientifically-driven outsourced clinical development services to the biotechnology, pharmaceutical and medical device industries. Our mission is to accelerate the global development of safe and effective medical therapeutics. We differentiate ourselves from our competitors by our disciplined operating model centered on providing full-service Phase I-IV clinical development services and our therapeutic expertise. We believe this combination results in timely and cost-
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    effective delivery of clinical development services for our customers. We believe that we are a partner of choice for small- and mid-sized biopharmaceutical companies based on our ability to consistently utilize our full-service, disciplined operating model to deliver timely and high-quality results for our customers.
    We focus on conducting clinical trials across all major therapeutic areas, with particular strength in Oncology, Metabolic Disease, Cardiology, Central Nervous System, or CNS, and Antiviral and Anti-infective, or AVAI. Our global platform includes approximately 6,000 employees across 44 countries as of June 30, 2025, providing our customers with broad access to diverse markets and patient populations as well as local regulatory expertise and market knowledge.
    How We Generate Revenue
    We earn fees through the performance of services detailed in our customer contracts. Contract scope and pricing is typically based on either a fixed-fee or unit-of-service model, with consideration of activities performed by third parties, as well as ancillary costs necessary to deliver on the contract scope that are reimbursable by our customers. Our contracts can range in duration from a few months to several years. These contracts are individually priced and negotiated based on the anticipated project scope, including the complexity of the project and the performance risks inherent in the project. The majority of our contracts are structured with an upfront fee that is collected at the time of contract signing, and the balance of the fee is collected over the duration of the contract either through an arranged billing schedule or upon completion of certain performance targets or defined milestones.
    Revenue, which is distinct from billing and cash receipt, is recognized based on the satisfaction of the individual performance obligations identified in each contract. Substantially all of our customer contracts consist of a single performance obligation, as the promise to transfer the individual services defined in the contracts are not separately identifiable from other promises in the contract, and therefore not distinct. Our performance obligations are generally satisfied over time and recognized as services are performed. The progression of our contract performance obligations are measured primarily utilizing the input method of cost to cost. Cancellation provisions in our contracts allow our customers to terminate a contract either immediately or according to advance notice terms specified within the applicable contract, which is typically 30 days. Contract cancellation may occur for various reasons, including, but not limited to, adverse patient reactions, lack of efficacy, or inadequate patient enrollment. Upon cancellation, we are entitled to fees for services rendered through the date of termination, including payment for subsequent services necessary to conclude the study or close out the contract. These fees are typically discussed and agreed upon with the customer and are realized as revenue when we believe the amount can be estimated reliably and its realization is probable. Changes in revenue from period to period are driven primarily by new business volume and task order execution activity, project cancellations, and the mix of active studies during a given period that can vary based on therapeutic area and/or study life cycle stage.
    Costs and Expenses
    Our costs and expenses are comprised primarily of our total direct costs, selling, general and administrative costs, depreciation and amortization and income taxes.
    Total Direct Costs
    Total direct costs are primarily driven by labor and related employee benefits, but also include contracted third party service related expenses, fees paid to site investigators, reimbursed out of pocket expenses, laboratory supplies and other expenses contributing to service delivery. The other costs of service delivery can include office rent, utilities, supplies and software licenses which are allocated between Total direct costs and selling, general and administrative expenses based on the estimated contribution among service delivery and support function efforts on a percentage basis. Total direct costs are expensed as incurred and are not deferred in anticipation of contracts being awarded or finalization of changes in scope. Total direct costs, as a percentage of net revenue, can vary from period to period due to project labor efficiencies, changes in workforce, compensation/bonus programs and service mix.
    Selling, General and Administrative
    Selling, general and administrative expenses are primarily driven by compensation and related employee benefits, as well as rent, utilities, supplies, software licenses, professional fees (e.g., legal and accounting expenses), bad debt expense, travel, marketing and other operating expenses.
    Depreciation
    Depreciation is provided on our property and equipment on the straight-line method at rates adequate to allocate the cost of the applicable assets over their estimated useful lives, which is three to five years for computer hardware, software, phone,
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    and medical imaging equipment, five to seven years for furniture and fixtures and other equipment, and thirty to forty years for buildings. Leasehold improvements are amortized on a straight-line basis over the shorter of the estimated useful life of the improvement or the associated remaining lease term.
    Amortization
    Amortization relates to finite-lived intangible assets recognized as expense using the straight-line method or using an accelerated method over their estimated useful lives of 15 years.
    Income Tax Provision
    Income tax provision consists of federal, state and local taxes on income in multiple jurisdictions. Our income tax is impacted by the pre-tax earnings in jurisdictions with varying tax rates and any related tax credits that may be available to us. Our current and future provision for income taxes will vary from statutory rates due to the impact of valuation allowances in certain countries, income tax incentives, certain non-deductible expenses, and other discrete items.
    Key Performance Metrics
    To evaluate the performance of our business, we utilize a variety of financial and performance metrics. These key measures include new business awards, cancellations and backlog.
    New Business Awards, Cancellations and Backlog
    New business awards represent the value of anticipated future net revenue that has been awarded during the period that is recognized in backlog. This value is recognized upon the signing of a contract or receipt of a written pre-contract confirmation from a customer that confirms an agreement in principle on budget and scope. New business awards also include contract amendments, or changes in scope, where the customer has provided written authorization for changes in budget and scope or has approved us to perform additional work as of the measurement date. Awards may not be recognized as backlog after consideration of a number of factors, including whether (i) the relevant net revenue is expected only after a pending regulatory hurdle, which might result in cancellation of the study, (ii) the customer funding needed for commencement of the study is not believed to have been secured or (iii) study timelines are uncertain or not well defined. In addition, study amounts that extend beyond a three-year timeline are not included in backlog. The number and amount of new business awards can vary significantly from period to period, and an award’s contractual duration can range from several months to several years based on customer and project specifications.
    Cancellations arise in the normal course of business and are reflected when we receive written confirmation from the customer to cease work on a contractual agreement. The majority of our customers can terminate our contracts without cause upon 30 days’ notice. Similar to new business awards, the number and amount of cancellations can vary significantly period over period due to timing of customer correspondence and study-specific circumstances.
    Net new business awards represent gross new business awards received in a period offset by total cancellations in that period. Net new business awards were $620.5 million and $1,120.6 million for the three and six months ended June 30, 2025, respectively. Net new business awards were $551.0 million and $1,166.5 million for the three and six months ended June 30, 2024, respectively.
    Backlog represents anticipated future net revenue from net new business awards that have not commenced or are currently in process but not complete. Reported backlog will fluctuate based on new business awards, changes in the scope of existing contracts, cancellations, revenue recognition on existing contracts and foreign exchange adjustments from non-U.S. dollar denominated backlog. As of June 30, 2025, our backlog decreased by $51.3 million, or 1.8%, to $2,873.6 million compared to $2,924.9 million as of June 30, 2024. Included within backlog as of June 30, 2025 was approximately $1,740.0 million to $1,760.0 million that we expect to convert to net revenue over the next twelve months, with the remainder expected to convert to net revenue thereafter.
    The effect of foreign currency adjustments on backlog was as follows: favorable foreign currency adjustments of $14.5 million for the three months ended June 30, 2025; favorable foreign currency adjustments of $21.4 million for the six months ended June 30, 2025; unfavorable foreign currency adjustments of $1.2 million for the three months ended June 30, 2024; and unfavorable foreign currency adjustments of $8.0 million for the six months ended June 30, 2024.
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    Backlog and net new business award metrics may not be reliable indicators of our future period revenue as they are subject to a variety of factors that may cause material fluctuations from period to period. These factors include, but are not limited to, changes in the scope of projects, cancellations, and duration and timing of services provided.
    Exchange Rate Fluctuations
    The majority of our contracts and operational transactions are U.S. dollar denominated. The Euro represents the largest foreign currency denomination of our contractual and operational exposure. As a result, a portion of our revenue and expenses are subject to exchange rate fluctuations. We have translated the Euro into U.S. dollars using the following average exchange rates based on data obtained from www.xe.com:
    Three Months Ended June 30,Six Months Ended June 30,
    2025202420252024
    U.S. Dollars per Euro:1.13 1.08 1.09 1.08 
    Results of Operations
    Three Months Ended June 30, 2025 compared to Three Months Ended June 30, 2024
    Three Months Ended June 30,
    (Amounts in thousands, except percentages)20252024
    Change
    % Change
    Revenue, net$603,311 $528,104 $75,207 14.2 %
    Direct service costs, excluding depreciation and amortization185,826 171,541 14,285 8.3 %
    Reimbursed out-of-pocket expenses237,472 202,725 34,747 17.1 %
    Total direct costs423,298 374,266 49,032 13.1 %
    Selling, general and administrative46,664 41,453 5,211 12.6 %
    Depreciation6,777 6,874 (97)(1.4)%
    Amortization237 361 (124)(34.3)%
    Total operating expenses476,976 422,954 54,022 12.8 %
    Income from operations126,335 105,150 21,185 
    Miscellaneous expense, net(2,875)(133)(2,742)
    Interest income, net1,078 5,465 (4,387)
    Income before income taxes124,538 110,482 14,056 
    Income tax provision34,278 22,131 12,147 
    Net income$90,260 $88,351 $1,909 
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    Six Months Ended June 30, 2025 compared to Six Months Ended June 30, 2024
    Six Months Ended June 30,
    (Amounts in thousands, except percentages)20252024
    Change
     
    % Change
    Revenue, net$1,161,881 $1,039,148 $122,733 11.8 %
    Direct service costs, excluding depreciation and amortization363,642 343,033 20,609 6.0 %
    Reimbursed out-of-pocket expenses439,876 387,135 52,741 13.6 %
    Total direct costs803,518 730,168 73,350 10.0 %
    Selling, general and administrative104,561 85,534 19,027 22.2 %
    Depreciation13,471 13,505 (34)(0.3)%
    Amortization473 722 (249)(34.5)%
    Total operating expenses922,023 829,929 92,094 11.1 %
    Income from operations239,858 209,219 30,639  
    Miscellaneous (expense) income, net(4,691)4,460 (9,151) 
    Interest income, net7,541 9,585 (2,044) 
    Income before income taxes242,708 223,264 19,444  
    Income tax provision37,853 32,322 5,531  
    Net income$204,855 $190,942 $13,913  
    Total revenue
    Total revenue increased by $75.2 million to $603.3 million for the three months ended June 30, 2025, from $528.1 million for the three months ended June 30, 2024. Total revenue increased by $122.7 million to $1,161.9 million for the six months ended June 30, 2025, from $1,039.1 million for the six months ended June 30, 2024. The increase for the three and six months ended June 30, 2025 was primarily driven by growth within the Metabolic, Oncology and Central Nervous System therapeutic areas, compared to the same periods in the prior year.
    Total direct costs
    Total direct costs increased by $49.0 million, to $423.3 million for the three months ended June 30, 2025 from $374.3 million for the three months ended June 30, 2024. Total direct costs increased by $73.4 million, to $803.5 million for the six months ended June 30, 2025 from $730.2 million for the six months ended June 30, 2024. The increase was primarily attributed to higher reimbursed out-of-pocket expenses and higher personnel costs to support the growth in service activities. Reimbursed out-of-pocket expenses, which can fluctuate significantly from period to period based on the timing of program initiation and closeout, increased by $34.7 million and $52.7 million for the three and six months ended June 30, 2025, compared to the same periods in the prior year. The higher personnel costs portion increased by $12.0 million and $17.4 million for the three and six months ended June 30, 2025, compared to the same periods in the prior year.
    Selling, general and administrative
    Selling, general and administrative expenses increased by $5.2 million, to $46.7 million for the three months ended June 30, 2025 from $41.5 million for the three months ended June 30, 2024. Selling, general and administrative expenses increased by $19.0 million, to $104.6 million for the six months ended June 30, 2025 from $85.5 million for the six months ended June 30, 2024. The increase was primarily attributed to higher personnel costs to support the growth in service activities. The higher personnel costs portion increased by $4.4 million and $19.0 million for the three and six months ended June 30, 2025, compared to the same periods in the prior year.
    Depreciation and Amortization
    Depreciation and amortization expense of $7.0 million for the three months ended June 30, 2025, remained relatively consistent with $7.2 million for the three months ended June 30, 2024. Depreciation and amortization expense of $13.9 million for the six months ended June 30, 2025, remained relatively consistent with $14.2 million for the six months ended June 30, 2024.
    Miscellaneous (expense) income, net
    -23-

    Table of Contents
    Miscellaneous expense, net increased by $2.7 million to $2.9 million for the three months ended June 30, 2025, from $0.1 million for the three months ended June 30, 2024. Miscellaneous (expense) income, net changed by $9.2 million to $4.7 million of expense for the six months ended June 30, 2025 from $4.5 million of income for the six months ended June 30, 2024. These changes were mainly attributable to foreign exchange gains and losses that arise in connection with the revaluation of short-term intercompany balances between our domestic and international subsidiaries and from the settlement of third-party accounts receivables and payables denominated in a currency other than the local currency of the entity making the payment, third-party investment gains or losses and proceeds from the recovery of a note receivable, compared to the same periods in the prior year.
    Interest income, net
    Interest income, net decreased by $4.4 million to $1.1 million for the three months ended June 30, 2025, from $5.5 million for the three months ended June 30, 2024. Interest income, net decreased by $2.0 million to $7.5 million for the six months ended June 30, 2025, from $9.6 million for the six months ended June 30, 2024. These changes were mainly attributable to decreased interest income on Cash and cash equivalents, compared to the same periods in the prior year.
    Income tax provision
    Income tax provision increased by $12.1 million, to $34.3 million for the three months ended June 30, 2025 from $22.1 million for the three months ended June 30, 2024. Income tax provision increased by $5.5 million, to $37.9 million for the six months ended June 30, 2025 from $32.3 million for the six months ended June 30, 2024. The overall effective tax rate for the three months ended June 30, 2025 was 27.5%, compared to an overall effective tax rate of 20.0% for the three months ended June 30, 2024. The overall effective tax rate for the six months ended June 30, 2025 was 15.6% compared to an overall effective tax rate of 14.5% for the six months ended June 30, 2024. The increase in the income tax provision and overall effective tax rate for the three months ended June 30, 2025 was primarily attributable to an increase in pre-tax book income, a decrease in excess tax benefits recognized from share-based compensation and a decrease in the estimated tax benefits related to Foreign Derived Intangible Income (FDII) compared to the same period in the prior year. The increase in the income tax provision and overall effective tax rate for the six months ended June 30, 2025 was primarily attributable to an increase in pre-tax book income and a decrease in the estimated tax benefits related to FDII, which was partially offset by an increase in excess tax benefits recognized from share-based compensation compared to the same period in the prior year.
    On July 4, 2025, the One Big Beautiful Bill Act (“OBBBA”) was enacted in the U.S. The OBBBA includes significant provisions, such as the permanent extension of certain expiring provisions of the Tax Cuts and Jobs Act, modifications to the international tax framework and the restoration of favorable tax treatment for certain business provisions. We are currently assessing its impact on our condensed consolidated financial statements.
    Liquidity and Capital Resources
    We assess our liquidity in terms of our ability to generate cash to fund our operating, investing and financing activities. Our principal sources of liquidity as of June 30, 2025 are operating cash flows and from borrowings under our unsecured credit facility consisting of up to a $600.0 million revolving line of credit which we entered into on September 30, 2019 (the “Credit Facility”), and has subsequently been amended. As of June 30, 2025, we had cash and cash equivalents of $46.3 million which decreased from $669.4 million as of December 31, 2024 primarily due to repurchases of common stock. Approximately $23.1 million of cash and cash equivalents, none of which was restricted, was held by our foreign subsidiaries as of June 30, 2025.
    As of June 30, 2025, we had $600.0 million available for borrowing under the Credit Facility. On July 17, 2025, the Company entered into Amendment No. 9 to the Loan Agreement, which decreased the aggregate principal amount that may be borrowed under the Credit Facility to up to $10.0 million. Our expected primary cash needs on both a short and long-term basis are for investment in operational growth, including additional lease commitments, capital expenditures, share repurchases, selective strategic bolt-on acquisitions, other investments, and other general corporate needs. We have historically funded our operations and growth with cash flow from operations and borrowings under our credit facilities. We expect to continue expanding our operations through organic growth and potentially highly selective bolt-on acquisitions and investments. As of June 30, 2025, cash commitments to support operating business needs include lease liabilities discussed in Note 8 of the Condensed Consolidated Financial Statements, purchase commitments discussed in Note 11 of the Condensed Consolidated Financial Statements and capital expenditures primarily related to infrastructure investments in our facilities, equipment and technology. Capital spending as a percentage of revenue decreased by 38 basis points to 1.39% in the six months ended June 30, 2025, compared to the same period in the prior year. We expect these activities will be funded from existing cash, cash flow from operations and, if necessary, borrowings under our existing or
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    future credit facilities or other debt. We have deemed that foreign earnings will be indefinitely reinvested and therefore we have not provided taxes on these earnings. While we do not anticipate the need to repatriate these foreign earnings for liquidity purposes given our cash flows from operations and borrowings under existing and future credit facilities, we would incur taxes on these earnings if the need for repatriation due to liquidity purposes arises.
    Six Months Ended June 30,
    Cash Flows (Amounts in thousands)20252024
    Net cash provided by operating activities$274,362 $269,074 
    Net cash used in investing activities(16,007)(10,260)
    Net cash (used in) provided by financing activities(886,530)8,326 
    Effect of exchange rates on cash, cash equivalents, and restricted cash5,069 (1,695)
    (Decrease) increase in cash, cash equivalents, and restricted cash$(623,106)$265,445 
    Cash Flow from Operating Activities
    Cash flows from operations are driven mainly by net income, deferred income tax provision, stock-based compensation expense, depreciation, noncash lease expense and net movement in advanced billings, accounts receivable and unbilled, net and prepaid expenses and other current assets. Advanced billings and accounts receivable and unbilled, net fluctuate on a regular basis as we perform our services, bill our customers and ultimately collect on those receivables. We attempt to negotiate payment terms in order to provide for payments prior to or soon after the provision of services, but this timing of collection can vary significantly on a period by period comparative basis.
    Net cash flows provided by operating activities was $274.4 million for the six months ended June 30, 2025 beginning with net income of $204.9 million. Adjustments to reconcile net income to net cash provided by operating activities were $82.8 million, primarily related to deferred income tax provision of $34.9 million, stock-based compensation expense of $22.8 million, depreciation of $13.5 million and noncash lease expense of $11.7 million. Changes in operating assets and liabilities used $13.3 million in operating cash flows and was primarily driven by increased accounts receivable and unbilled, net of $82.0 million and increased prepaid expenses and other current assets of 33.1 million, partially offset by increased advanced billings of $98.2 million.
    Net cash flows provided by operating activities was $269.1 million for the six months ended June 30, 2024 beginning with net income of $190.9 million. Adjustments to reconcile net income to net cash provided by operating activities were $28.8 million, primarily related to depreciation of $13.5 million, noncash lease expense of $11.5 million and stock-based compensation expense of $7.9 million. Changes in operating assets and liabilities provided $49.4 million in operating cash flows and was primarily driven by increased advanced billings of $78.6 million, partially offset by increased prepaid expenses and other current assets of $11.3 million and decreased lease liabilities of $11.0 million.
    Cash Flow from Investing Activities
    Net cash used in investing activities was $16.0 million for the six months ended June 30, 2025 primarily consisting of property and equipment expenditures.
    Net cash used in investing activities was $10.3 million for the six months ended June 30, 2024 primarily consisting of property and equipment expenditures of $18.4 million, partially offset by $8.1 million in other investing activity.
    Cash Flow from Financing Activities
    Net cash used in financing activities was $886.5 million for the six months ended June 30, 2025 primarily related to $912.8 million in repurchases of common stock, partially offset by proceeds from stock option exercises of $26.3 million.
    Net cash provided by financing activities was $8.3 million for the six months ended June 30, 2024 related to proceeds from stock option exercises.
    Share Repurchases
    In 2022, the Company’s Board of Directors (“Board”) approved a stock repurchase program of up to $500.0 million. In the first and second quarters of 2025, the Board approved increases of $600.0 million and $1.0 billion, respectively, to the Company’s stock repurchase program bringing the total repurchase authorization up to $2.1 billion. During the three and six months ended June 30, 2025, the Company repurchased 1,754,264 shares and 2,947,275 shares for $518.5 million and
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    Table of Contents
    $908.4 million, respectively. The Company did not execute any share repurchases during the three and six months ended June 30, 2024. As of June 30, 2025, the Company has remaining authorization of $826.3 million under the repurchase program.

    Repurchases under the share repurchase program are executed in the open market or negotiated transactions under trading plans put in place pursuant to Rule 10b5-1. The Company constructively retired the repurchased shares associated with these approved share repurchases, except for a small portion which were retained as Treasury Shares on the condensed consolidated statements of shareholders' equity. Retired share repurchase amounts paid in excess of par value are reflected within Accumulated deficit/Retained earnings in the Company’s condensed consolidated balance sheets.
    Indebtedness
    As of June 30, 2025, we had no indebtedness. Refer to Note 7 of the Notes to Condensed Consolidated Financial Statements for details regarding our Credit Facility.
    Critical Accounting Policies and Estimates
    The preparation of financial statements in accordance with generally accepted accounting principles in the United States of America, or U.S. GAAP, requires us to make a variety of decisions which affect reported amounts and related disclosures, including the selection of appropriate accounting principles and the assumptions on which to base accounting estimates. In reaching such decisions, we apply judgment based on our understanding and analysis of the relevant circumstances, including our historical experience and other assumptions. Actual results could differ from our estimates. We are committed to incorporating accounting principles, assumptions and estimates that promote the representational faithfulness, verifiability, neutrality and transparency of the accounting information included in the financial statements.
    There have been no significant changes in the critical accounting policies and estimates as previously described in our Annual Report on Form 10-K for the fiscal year ended December 31, 2024.
    Effect of Recent Accounting Pronouncements
    Refer to Note 1 of the Condensed Consolidated Financial Statements for management’s discussion of the effect of recent accounting pronouncements.
    Item 3. Quantitative and Qualitative Disclosures About Market Risk
    There have been no material changes to our quantitative and qualitative disclosures about market risk as compared to the quantitative and qualitative disclosures about market risk described in our Annual Report on Form 10-K for the fiscal year ended December 31, 2024.
    Item 4. Controls and Procedures
    Limitations on Effectiveness of Controls and Procedures
    In designing and evaluating our disclosure controls and procedures, management recognizes that any controls and procedures, no matter how well designed and operated, can provide only reasonable assurance of achieving the desired control objectives. In addition, the design of disclosure controls and procedures must reflect the fact that there are resource constraints and that management is required to apply judgment in evaluating the benefits of possible controls and procedures relative to their costs.
    Evaluation of Disclosure Controls and Procedures
    The Company’s management, with the participation of the Chief Executive Officer (the Principal Executive Officer) and Chief Financial Officer (the Principal Financial Officer), has evaluated the effectiveness of the Company’s disclosure controls and procedures, as defined in Rules 13(a)-15(e) and 15(d) -15(e) of the Securities Exchange Act of 1934 (“Exchange Act”), as of the end of the period covered by this report. Based on this evaluation, we concluded that, as of the end of the period covered by this report, our disclosure controls and procedures were effective in providing reasonable assurance that information required to be disclosed by us in the reports we file or submit under the Exchange Act is recorded, processed, summarized and reported within the time periods specified in the SEC’s forms and rules, and the material information relating to the Company is accumulated and communicated to management, including the Chief Executive Officer and Chief Financial Officer, as appropriate, to allow timely decisions regarding required disclosures.
    -26-

    Table of Contents
    Control systems, no matter how well designed and operated, can provide only reasonable, not absolute, assurance that control objectives are met. Because of inherent limitations in all control systems, no evaluation of controls can provide assurance that all control issues and instances of fraud, if any, within a company will be detected. Additionally, controls can be circumvented by individuals, by collusion of two or more people or by management override. Over time, controls can become inadequate because of changes in conditions or the degree of compliance may deteriorate. Further, the design of any system of controls is based in part upon assumptions about the likelihood of future events. There can be no assurance that any design will succeed in achieving its stated goals under all future conditions. Because of the inherent limitations in any cost-effective control system, misstatements due to errors or fraud may occur and not be detected.
    Changes in Internal Control over Financial Reporting
    In the ordinary course of business, we routinely enhance our information systems by either upgrading current systems or implementing new ones. There were no changes in our internal control over financial reporting that occurred during the three months ended June 30, 2025 that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.
    PART II—OTHER INFORMATION
    Item 1. Legal Proceedings
    We are party to legal proceedings incidental to our business. While the outcome of these matters could differ from management’s expectations, we do not believe that the resolution of these matters is reasonably likely to have a material adverse effect to our financial statements.
    Item 1A. Risk Factors
    For a discussion of our potential risks and uncertainties, see the information under the heading “Risk Factors” in our Annual Report on Form 10-K for the fiscal year ended December 31, 2024. There have been no significant changes from the risk factors previously disclosed in our Annual Report.
    Item 2. Unregistered Sales of Equity Securities and Use of Proceeds
    Share Repurchases
    This table provides certain information with respect to our monthly repurchases of the Company’s common stock during the second quarter of fiscal year 2025:
    PeriodTotal Number of Shares PurchasedAverage Price Paid Per ShareTotal Number of Shares Purchased as Part of Publicly Announced PlanApproximate Dollar Value of Shares That May Yet Be Purchased Under the Plan
    April 1, 2025, through April 30, 20251,198,556 $294.00 10,952,164 $992,421,570 
    May 1, 2025, through May 31, 2025233,447 $292.30 11,185,611 $924,185,657 
    June 1, 2025, through June 30, 2025322,261 $303.88 11,507,872 $826,256,169 
    Total1,754,264 $295.59 11,507,872 
    All share repurchases were made using cash resources and executed pursuant to established Rule 10b5-1 trading plans. Our share repurchases may occur through open market purchases or negotiated transactions. The above table excludes shares repurchased to settle employee tax withholding related to the vesting of stock awards.
    We returned $518.5 million to shareholders in the form of share repurchases in the second quarter of fiscal year 2025. Refer to Note 1 – Basis of Presentation of the Notes to Condensed Consolidated Financial Statements (Part I, Item 1 of this Form 10-Q) for further discussion regarding share repurchases.
    Use of Proceeds from Registered Securities
    Not applicable.
    Item 3. Defaults Upon Senior Securities
    None.
    -27-

    Table of Contents
    Item 4. Mine Safety Disclosures
    Not applicable.
    Item 5. Other Information
    During the three months ended June 30, 2025, no director or officer of the Company adopted or terminated a “Rule 10b5-1 trading arrangement” or “non-Rule 10b5-1 trading arrangement,” as each term is defined in Item 408(a) of Regulation S-K.
    Item 6. Exhibits
    The exhibits in the accompanying Exhibit Index preceding the signature page are filed or furnished as a part of this report and are incorporated herein by reference.
    -28-

    Table of Contents
    EXHIBIT INDEX
    Incorporated by Reference
    Exhibit
    Number
    Exhibit DescriptionFormFile No.Exhibit
    Filing
    Date
    Filed/
    Furnished
    Herewith
    10.1
    Amendment No. 8 dated April 18, 2025 to Loan Documents
    8-K001-3785610.14/21/2025
    #10.2
    Medpace Holdings, Inc. 2016 Amended and Restated Incentive Award Plan
    8-K001-3785610.15/16/2025
    31.1
    Rule 13a-14(a) / 15d-14(a) Certification of Chief Executive Officer
    *
    31.2
    Rule 13a-14(a) / 15d-14(a) Certification of Chief Financial Officer
    *
    32.1
    Section 1350 Certification of Chief Executive Officer
    **
    32.2
    Section 1350 Certification of Chief Financial Officer
    **
    101.INSInline XBRL Instance Document – the instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL document*
    101.SCHInline XBRL Taxonomy Extension Schema Document*
    101.CALInline XBRL Taxonomy Calculation Linkbase Document*
    101.DEFInline XBRL Taxonomy Extension Definition Linkbase Document*
    101.LABInline XBRL Taxonomy Extension Label Linkbase Document*
    101.PREInline XBRL Taxonomy Extension Presentation*
    104Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101) 
    *    Filed herewith.
    **    Furnished herewith.
    #    Indicates management contract or compensatory plan.

    -29-

    Table of Contents
    SIGNATURES
    Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
    MEDPACE HOLDINGS, INC.
    /s/ Kevin M. Brady
    Kevin M. Brady
    Chief Financial Officer
    (Principal Financial Officer)
    Date: July 22, 2025
    -30-
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