• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Dashboard
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlerts
    Company
    AboutQuantisnow PlusContactJobs
    Legal
    Terms of usePrivacy policyCookie policy

    SEC Form SC 13D/A filed by Freeline Therapeutics Holdings plc (Amendment)

    2/22/24 4:06:06 PM ET
    $FRLN
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $FRLN alert in real time by email
    SC 13D/A 1 d797091dsc13da.htm SC 13D/A SC 13D/A

     

     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    Washington, D.C. 20549

     

     

    SCHEDULE 13D

    Under the Securities Exchange Act of 1934

    (Amendment No. 3)*

     

     

    Freeline Therapeutics Holdings plc

    (Name of Issuer)

    American Depositary Shares and Ordinary Shares, nominal value £0.00001 per share

    (Title of Class of Securities)

    G3664N 103

    (CUSIP Number)

    Alasdair Moodie, General Counsel

    Syncona Investment Management Limited

    2nd Floor, 8 Bloomsbury Street

    London WC1B 3SR, United Kingdom

    020 3981 8888

    (Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)

    February 20, 2024

    (Date of Event Which Requires Filing of this Statement)

     

     

    If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. ☐

     

     

    Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Rule 13d-7 for other parties to whom copies are to be sent.

     

     

     

    *

    The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

    The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

     

     

     


       SCHEDULE 13D   
         
    CUSIP NO. G3664N 103    13D    Page 1 of 12

     

    1   

    NAMES OF REPORTING PERSON

     

    Syncona Portfolio Limited

    2   

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ☐  (b) ☒

     

    3   

    SEC USE ONLY

     

    4   

    SOURCE OF FUNDS

     

    WC

    5   

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

    ☐

    6   

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Guernsey

    NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

       7   

    SOLE VOTING POWER

     

    0

       8   

    SHARED VOTING POWER

     

    65,872,764 (1)

       9   

    SOLE DISPOSITIVE POWER

     

    0

       10   

    SHARED DISPOSITIVE POWER

     

    65,872,764 (1)

    11   

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    65,872,764 (1)

    12   

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

     

    ☐

    13   

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

    100% (2)

    14   

    TYPE OF REPORTING PERSON

     

    CO

     

    (1)

    Consists of (i) 15,864,527 ordinary shares and 1,466,507 American Depositary Shares (“ADSs”) (which represent 21,997,605 ordinary shares) held by Syncona Portfolio Limited and (ii) 28,010,632 ordinary shares held beneficially by Bidco 1354 Limited. Each ADS represents 15 ordinary shares, nominal value £0.00001 per share, of the Issuer. The ordinary shares (including those represented by the ADSs) are collectively referred to as the “Ordinary Shares”.

    (2)

    The percentages used in this Amendment No. 3 to Schedule 13D are calculated based on 65,872,764 Ordinary Shares outstanding as of February 20, 2024, following the consummation of the Acquisition (as defined in Item 4 below).


       SCHEDULE 13D   
         
    CUSIP NO. G3664N 103    13D    Page 2 of 12

     

    1   

    NAMES OF REPORTING PERSON

     

    Syncona Holdings Limited

    2   

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ☐  (b) ☒

     

    3   

    SEC USE ONLY

     

    4   

    SOURCE OF FUNDS

     

    WC

    5   

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

    ☐

    6   

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Guernsey

    NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

       7   

    SOLE VOTING POWER

     

    0

       8   

    SHARED VOTING POWER

     

    65,872,764 (1)

       9   

    SOLE DISPOSITIVE POWER

     

    0

       10   

    SHARED DISPOSITIVE POWER

     

    65,872,764 (1)

    11   

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    65,872,764 (1)

    12   

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

     

    ☐

    13   

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

    100% (2)

    14   

    TYPE OF REPORTING PERSON

     

    CO

     

    (1)

    Consists of (i) 15,864,527 ordinary shares and 1,466,507 American Depositary Shares (“ADSs”) (which represent 21,997,605 ordinary shares) held by Syncona Portfolio Limited and (ii) 28,010,632 ordinary shares held beneficially by Bidco 1354 Limited. Each ADS represents 15 ordinary shares, nominal value £0.00001 per share, of the Issuer. The ordinary shares (including those represented by the ADSs) are collectively referred to as the “Ordinary Shares”.

    (2)

    The percentages used in this Amendment No. 3 to Schedule 13D are calculated based on 65,872,764 Ordinary Shares outstanding as of February 20, 2024, following the consummation of the Acquisition (as defined in Item 4 below).


       SCHEDULE 13D   
         
    CUSIP NO. G3664N 103    13D    Page 3 of 12

     

    1   

    NAMES OF REPORTING PERSON

     

    Syncona Investment Management Limited

    2   

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ☐  (b) ☒

     

    3   

    SEC USE ONLY

     

    4   

    SOURCE OF FUNDS

     

    WC

    5   

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

    ☐

    6   

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    United Kingdom

    NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

       7   

    SOLE VOTING POWER

     

    0

       8   

    SHARED VOTING POWER

     

    65,872,764 (1)

       9   

    SOLE DISPOSITIVE POWER

     

    0

       10   

    SHARED DISPOSITIVE POWER

     

    65,872,764 (1)

    11   

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    65,872,764 (1)

    12   

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

     

    ☐

    13   

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

    100% (2)

    14   

    TYPE OF REPORTING PERSON

     

    CO

     

    (1)

    Consists of (i) 15,864,527 ordinary shares and 1,466,507 American Depositary Shares (“ADSs”) (which represent 21,997,605 ordinary shares) held by Syncona Portfolio Limited and (ii) 28,010,632 ordinary shares held beneficially by Bidco 1354 Limited. Each ADS represents 15 ordinary shares, nominal value £0.00001 per share, of the Issuer. The ordinary shares (including those represented by the ADSs) are collectively referred to as the “Ordinary Shares”.

    (2)

    The percentages used in this Amendment No. 3 to Schedule 13D are calculated based on 65,872,764 Ordinary Shares outstanding as of February 20, 2024, following the consummation of the Acquisition (as defined in Item 4 below).


       SCHEDULE 13D   
         
    CUSIP NO. G3664N 103    13D    Page 4 of 12

     

    1   

    NAMES OF REPORTING PERSON

     

    Syncona Limited

    2   

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ☐  (b) ☒

     

    3   

    SEC USE ONLY

     

    4   

    SOURCE OF FUNDS

     

    WC

    5   

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

    ☐

    6   

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Guernsey

    NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

       7   

    SOLE VOTING POWER

     

    0

       8   

    SHARED VOTING POWER

     

    65,872,764 (1)

       9   

    SOLE DISPOSITIVE POWER

     

    0

       10   

    SHARED DISPOSITIVE POWER

     

    65,872,764 (1)

    11   

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    65,872,764 (1)

    12   

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

     

    ☐

    13   

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

    100% (2)

    14   

    TYPE OF REPORTING PERSON

     

    CO

     

    (1)

    Consists of (i) 15,864,527 ordinary shares and 1,466,507 American Depositary Shares (“ADSs”) (which represent 21,997,605 ordinary shares) held by Syncona Portfolio Limited and (ii) 28,010,632 ordinary shares held beneficially by Bidco 1354 Limited. Each ADS represents 15 ordinary shares, nominal value £0.00001 per share, of the Issuer. The ordinary shares (including those represented by the ADSs) are collectively referred to as the “Ordinary Shares”.

    (2)

    The percentages used in this Amendment No. 3 to Schedule 13D are calculated based on 65,872,764 Ordinary Shares outstanding as of February 20, 2024, following the consummation of the Acquisition (as defined in Item 4 below).


       SCHEDULE 13D   
         
    CUSIP NO. G3664N 103    13D    Page 5 of 12

     

    1   

    NAMES OF REPORTING PERSON

     

    Bidco 1354 Limited

    2   

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ☐  (b) ☒

     

    3   

    SEC USE ONLY

     

    4   

    SOURCE OF FUNDS

     

    WC

    5   

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2€

     

    ☐

    6   

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    England and Wales

    NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

       7   

    SOLE VOTING POWER

     

    28,010,632 (1)

       8   

    SHARED VOTING POWER

     

    0

       9   

    SOLE DISPOSITIVE POWER

     

    28,010,632 (1)

       10   

    SHARED DISPOSITIVE POWER

     

    0

    11   

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    28,010,632 (1)

    12   

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

     

    ☐

    13   

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

    42.5% (2)

    14   

    TYPE OF REPORTING PERSON

     

    CO

     

    (1)

    Consists of 28,010,632 ordinary shares, nominal value £0.00001 per share (the “Ordinary Shares”), held beneficially by Bidco 1354 Limited.

    (2)

    The percentages used in this Amendment No. 3 to Schedule 13D are calculated based on 65,872,764 Ordinary Shares outstanding as of February 20, 2024, following the consummation of the Acquisition (as defined in Item 4 below).


       SCHEDULE 13D   
         
    CUSIP NO. G3664N 103    13D    Page 6 of 12

     

    1   

    NAMES OF REPORTING PERSON

     

    Roel Bulthuis

    2   

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ☐  (b) ☒

     

    3   

    SEC USE ONLY

     

    4   

    SOURCE OF FUNDS

     

    PF

    5   

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

    ☐

    6   

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Netherlands

    NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

       7   

    SOLE VOTING POWER

     

    0

       8   

    SHARED VOTING POWER

     

    65,872,764 (1)

       9   

    SOLE DISPOSITIVE POWER

     

    0

       10   

    SHARED DISPOSITIVE POWER

     

    65,872,764 (1)

    11   

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    65,872,764 (1)

    12   

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

     

    ☐

    13   

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

    100% (2)

    14   

    TYPE OF REPORTING PERSON

     

    IN

     

    (1)

    Consists of (i) 15,864,527 ordinary shares and 1,466,507 American Depositary Shares (“ADSs”) (which represent 21,997,605 ordinary shares) held by Syncona Portfolio Limited and (ii) 28,010,632 ordinary shares held beneficially by Bidco 1354 Limited. Each ADS represents 15 ordinary shares, nominal value £0.00001 per share, of the Issuer. The ordinary shares (including those represented by the ADSs) are collectively referred to as the “Ordinary Shares”.

    (2)

    The percentages used in this Amendment No. 3 to Schedule 13D are calculated based on 65,872,764 Ordinary Shares outstanding as of February 20, 2024, following the consummation of the Acquisition (as defined in Item 4 below).


       SCHEDULE 13D   
         
    CUSIP NO. G3664N 103    13D    Page 7 of 12

     

    1   

    NAMES OF REPORTING PERSON

     

    Christopher Hollowood

    2   

    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

    (a) ☐  (b) ☒

     

    3   

    SEC USE ONLY

     

    4   

    SOURCE OF FUNDS

     

    PF

    5   

    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

    ☐

    6   

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    United Kingdom

    NUMBER OF

    SHARES

    BENEFICIALLY

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH

       7   

    SOLE VOTING POWER

     

    0

       8   

    SHARED VOTING POWER

     

    65,872,764 (1)

       9   

    SOLE DISPOSITIVE POWER

     

    0

       10   

    SHARED DISPOSITIVE POWER

     

    65,872,764 (1)

    11   

    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    65,872,764 (1)

    12   

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

     

    ☐

    13   

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

    100% (2)

    14   

    TYPE OF REPORTING PERSON

     

    IN

     

    (1)

    Consists of (i) 15,864,527 ordinary shares and 1,466,507 American Depositary Shares (“ADSs”) (which represent 21,997,605 ordinary shares) held by Syncona Portfolio Limited and (ii) 28,010,632 ordinary shares held beneficially by Bidco 1354 Limited. Each ADS represents 15 ordinary shares, nominal value £0.00001 per share, of the Issuer. The ordinary shares (including those represented by the ADSs) are collectively referred to as the “Ordinary Shares”.

    (2)

    The percentages used in this Amendment No. 3 to Schedule 13D are calculated based on 65,872,764 Ordinary Shares outstanding as of February 20, 2024, following the consummation of the Acquisition (as defined in Item 4 below).


       SCHEDULE 13D   
         
    CUSIP NO. G3664N 103    13D    Page 8 of 12

     

    Explanatory Note

    This Amendment No. 3 to Schedule 13D (this “Amendment No. 3”) amends and supplements the statement on Schedule 13D filed with the United States Securities and Exchange Commission (the “SEC”) on March 25, 2022, as amended by Amendment No. 1 filed with the SEC on October 18, 2023 and Amendment No. 2 filed with the SEC on November 24, 2023 (the “Schedule 13D”) and is being filed by Syncona Portfolio Limited (“Syncona”), Syncona Holdings Limited, Syncona Limited, Syncona Investment Management Limited, Bidco 1354 Limited (“Bidco”), Roel Bulthuis and Christopher Hollowood (collectively, the “Reporting Persons”) with respect to the share capital of Freeline Therapeutics Holdings plc (the “Issuer”). This Amendment No. 3 also reflects the addition of Bidco, a wholly owned subsidiary of Syncona, as a new Reporting Person.

    Information and defined terms reported in the Schedule 13D remain in effect except to the extent they are amended or superseded by information or defined terms contained in this Amendment No. 3.

     

    Item 2.

    Identity and Background.

    Item 2 of the Schedule 13D is hereby amended and supplemented as follows:

    (a) Bidco is a wholly owned subsidiary of Syncona.

    (b) The address of Bidco is 2nd Floor, 8 Bloomsbury Street, London WC1B 3SR, United Kingdom.

    (c) Bidco was formed for the sole purpose of facilitating the Acquisition (as defined below) pursuant to the Implementation Agreement (as defined below). Bidco has not engaged, and does not expect to engage, in any business other than in connection with the Acquisition.

    (d)-(e) During the last five years, Bidco has not been (i) convicted in a criminal proceeding (excluding traffic violations or similar misdemeanors) or (ii) a party to a civil proceeding of a judicial or administrative body of competent jurisdiction and as a result of such proceeding was or is subject to a judgment, decree or final order enjoining future violations of, or prohibiting or mandating activities subject to, federal or state securities laws or finding any violation with respect to such laws.

    (f) Bidco is organized under the laws of England and Wales.

     

    Item 4.

    Purpose of Transaction.

    Item 4 of the Schedule 13D is hereby amended and supplemented as follows:

    As previously disclosed, on November 22, 2023, the Issuer entered into an Implementation Agreement (the “Implementation Agreement”) with Bidco, pursuant to which Bidco agreed to acquire the entire issued and to be issued share capital of the Issuer (the “Issuer Shares”) for $6.50 in cash per American Depositary Share (the “ADS”) (the “Consideration”), excluding any treasury shares, any Issuer Shares held by Bidco or its affiliates, and certain pre-initial public offering equity awards forfeited upon the termination of the holder’s employment (collectively, the “Excluded Shares”). Under the terms of the Implementation Agreement, the acquisition (the “Acquisition”) would be implemented by means of a scheme of arrangement under Part 26 of the UK Companies Act 2006 (the “Scheme”).

    On February 12, 2024, at a meeting of the Issuer’s shareholders (the “Scheme Shareholders”) convened by the High Court of Justice of England and Wales (the “Court”), the Scheme Shareholders voted in favor of the resolution to approve the Scheme. At a general meeting of the Issuer’s shareholders, the Issuer’s shareholders voted in favor of the resolution to approve the implementation of the Scheme, including amending the articles of association of the Issuer in connection with the Scheme and giving the Issuer’s directors authority to take all necessary action to carry the Scheme into effect. Later on that same date, the Issuer and Syncona Limited issued a joint press release announcing such approvals by the shareholders, a copy of which is attached as Exhibit 99.7 hereto.


       SCHEDULE 13D   
         
    CUSIP NO. G3664N 103    13D    Page 9 of 12

     

    On February 19, 2024, the Court issued a court order sanctioning the Scheme (the “Court Order”). On February 20, 2024, the Court Order (together with a copy of the Scheme Circular) has been delivered to the Registrar of Companies in England and Wales, upon which the Scheme has become effective in accordance with its terms (the “Effective Date”). Later on that same date, the Issuer and Syncona Limited issued a joint press release announcing that the Scheme became effective, a copy of which is attached as Exhibit 99.8 hereto.

    In accordance with the terms of the Scheme, all of the issued and outstanding Issuer Shares that are not the Excluded Shares (the “Scheme Shares”) will be transferred to Bidco (and/or its nominees), in consideration for which each holder of Scheme Shares whose name appears in the register of members of the Issuer on February 19, 2024 at 6:00 p.m. (GMT) (the “Scheme Record Time”) will receive $0.433333 in cash per Scheme Share (equivalent to $6.50 in cash per ADS) held by such holder at the Scheme Record Time.

    In addition, following the sanction of the Scheme by the Court, (i) awards granted under the Freeline Equity Incentive Plan, Freeline Equity Inducement Plan and Freeline Share Option Plan were, in accordance with the rules of the applicable Issuer’s share plans (from time to time), cancelled in consideration for a cash payment (payable by the Issuer in the next practicable payroll following the Effective Date) equal in value to the Consideration that the relevant holder would have received in respect of the Acquisition had their awards fully vested and been settled in ordinary shares of the Issuer and subsequently transferred to Bidco in accordance with the Scheme (net of any option exercise price and applicable income tax and social security contributions for which any Issuer and its subsidiaries is required to withhold and account for to the relevant tax authority), and any such award which, immediately before the hearing of the Court to sanction the Scheme had an exercise price which exceeded or was equal to the Consideration payable under the Scheme (being $0.433333 per Scheme Share, equivalent to $6.50 in cash per ADS), was cancelled by the Issuer for nil consideration; (iii) the ordinary shares of the Issuer held under the terms of the Freeline Therapeutics Holdings plc 2020 Employee Share Purchase Plan were subject to the Scheme on the same terms as all other Scheme Shares; and (iv) all employee shares, whether or not they remained subject to the vesting arrangements pursuant to the IPO Vesting Agreement dated August 11, 2020, immediately prior to the sanction of the Scheme by the Court, were deemed fully vested upon the sanction of the Scheme by the Court and were subject to the Scheme on the same terms as all other Scheme Shares.

    In connection with the Scheme becoming effective, Julia Gregory, Martin Andrews, Jeffrey Chodakewitz, Colin Love and Paul Schneider have each tendered their resignations and stepped down from the Issuer’s board of directors with effect from the Effective Date.

    As a result of the Scheme, the ADSs ceased to trade on the Nasdaq Capital Market (“Nasdaq”) prior to market open of trading on February 20, 2024, and the Issuer became a private company beneficially owned by the Syncona group. On February 20, 2024, Nasdaq filed an application on Form 25 with the SEC to withdraw registration of the ADSs under the Securities Exchange Act of 1934, as amended (the “Exchange Act”). The deregistration will become effective 90 days after the filing of Form 25 or such shorter period as may be determined by the SEC. In addition, the Issuer intends to suspend its reporting obligations under the Exchange Act by filing a certification and notice on Form 15 with the SEC. The Issuer’s reporting obligations under the Exchange Act will be suspended immediately as of the filing date of Form 15 and will terminate once the deregistration becomes effective.

    The foregoing description of the Implementation Agreement is not intended to be complete and is qualified in its entirety by reference to the full text of the Implementation Agreement, which was attached as Exhibit 99.1 to the Report of Foreign Private Issuer to Form 6-K filed by the Issuer with the SEC on November 22, 2023.

     

    Item 5.

    Interest in Securities of the Issuer.

    Item 5 of the Schedule 13D is hereby amended and supplemented as follows:

    The information set forth in Item 4 of this Amendment No. 3 is hereby incorporated by reference into this Item 5.

    See Items 11 and 13 of the cover pages to this Amendment No. 3 for the aggregate number and percentage of ordinary shares and ADSs that are beneficially owned by each Reporting Person as of the date hereof. See Items 7 through 10 of the cover pages to this Amendment No. 3 for the number of ordinary shares and ADSs that are beneficially owned by each Reporting Person as of the date hereof as to whether there is sole or shared power to vote or direct the vote, and sole or shared power to dispose or direct the disposition.


       SCHEDULE 13D   
         
    CUSIP NO. G3664N 103    13D    Page 10 of 12

     

    Item 6.

    Contracts, Arrangements, Understandings or Relationships with Respect to Securities of the Issuer.

    Item 6 of the Schedule 13D is hereby amended and supplemented as follows:

    The information set forth in Item 4 of this Amendment No. 3 is hereby incorporated by reference into this Item 6.

     

    Item 7.

    Material to be Filed as Exhibits.

    Item 7 of the Schedule 13D is hereby amended and supplemented as follows:

     

    Exhibit 99.7    Joint Press Release issued by the Issuer and Syncona Limited, dated February  12, 2024 (Incorporated by reference to Exhibit 99.1 to the Report of Foreign Private Issuer on Form 6-K filed by the Issuer on February  12, 2024 (File No. 001-39431)).
    Exhibit 99.8    Joint Press Release issued by the Issuer and Syncona Limited, dated February  20, 2024 (Incorporated by reference to Exhibit 99.1 to the Report of Foreign Private Issuer on Form 6-K filed by the Issuer on February  20, 2024 (File No. 001-39431)).
    Exhibit 99.9    Joint Filing Statement, dated February 22, 2024.


    SIGNATURE

    After reasonable inquiry and to the best of the undersigned’s knowledge and belief, the undersigned hereby certifies that the information set forth in this statement is true, complete and correct.

    Dated: February 22, 2024

     

    SYNCONA PORTFOLIO LIMITED
    By:   /s/ Robert Hutchinson
    Name:   Robert Hutchinson
    Title:   Director
    SYNCONA HOLDINGS LIMITED
    By:   /s/ Robert Hutchinson
    Name:   Robert Hutchinson
    Title:   Director
    SYNCONA INVESTMENT MANAGEMENT LIMITED
    By:   /s/ Christopher Hollowood
    Name:   Christopher Hollowood
    Title:   CEO
    SYNCONA LIMITED
    By:   /s/ Robert Hutchinson
    Name:   Robert Hutchinson
    Title:   Director
    BIDCO 1354 LIMITED
    By:   /s/ Alex Hamilton
    Name:   Alex Hamilton
    Title:   Director

     

    /s/ Roel Bulthuis
    Roel Bulthuis
    /s/ Christopher Hollowood
    Christopher Hollowood
    Get the next $FRLN alert in real time by email

    Chat with this insight

    Save time and jump to the most important pieces.

    Recent Analyst Ratings for
    $FRLN

    DatePrice TargetRatingAnalyst
    2/1/2022Overweight → Equal-Weight
    Morgan Stanley
    1/7/2022Neutral → Buy
    Redburn
    11/29/2021$10.00Buy
    BTIG
    8/18/2021$30.00 → $20.00Buy
    HC Wainwright & Co.
    8/17/2021$27.00 → $8.00Overweight → Neutral
    JP Morgan
    8/17/2021Overweight → Neutral
    JP Morgan
    More analyst ratings

    $FRLN
    Press Releases

    Fastest customizable press release news feed in the world

    See more
    • Freeline to Present New Data on its Gaucher and Parkinson's Disease Programs at the American Society of Gene and Cell Therapy (ASGCT) 27th Annual Meeting

      Late-breaking oral presentation on results from Phase 1/2 study of FLT201 in Gaucher disease Poster presentation to highlight Freeline's GBA1 Parkinson's disease research program LONDON, April 24, 2024 (GLOBE NEWSWIRE) -- Freeline Therapeutics today announced the acceptance of multiple abstracts, including one for a late-breaking oral presentation on new clinical data from its Gaucher disease program, at the upcoming American Society of Gene and Cell Therapy (ASGCT) 27th Annual Meeting taking place May 7-11, 2024 in Baltimore, Maryland. "Gaucher disease is a severe and progressive disorder that leads to a wide range of symptoms, including enlarged organs, bone pain and fractures, low bl

      4/24/24 4:00:00 PM ET
      $FRLN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Acquisition of Freeline by Syncona Becomes Effective

      LONDON, Feb. 20, 2024 (GLOBE NEWSWIRE) -- Freeline Therapeutics Holdings plc (NASDAQ:FRLN) ("Freeline") and Syncona Ltd ("Syncona") today announced that, in connection with Syncona's acquisition of Freeline by way of a scheme of arrangement (the "Scheme"), the Scheme has been sanctioned by the Court and the court order (together with a copy of the scheme circular published by Freeline on January 18, 2024 (the "Scheme Circular") has been delivered to the Registrar of Companies.   Accordingly, the Scheme has become Effective in accordance with its terms and the entire issued share capital of Freeline is now owned or controlled by Syncona Portfolio Limited. Capitalized terms in this an

      2/20/24 7:00:00 AM ET
      $FRLN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Freeline Shareholders Approve Acquisition by Syncona

      LONDON, Feb. 12, 2024 (GLOBE NEWSWIRE) -- Freeline Therapeutics Holdings plc (NASDAQ:FRLN) ("Freeline") and Syncona Ltd ("Syncona") today announced that Freeline's shareholders have approved the proposal for Bidco 1354 Limited ("Bidco"), a wholly owned subsidiary of Syncona Portfolio Limited ("Syncona Portfolio"), to acquire all shares of Freeline not currently owned by Syncona Portfolio for $6.50 per American Depositary Share ("ADS") in cash (the "Acquisition"). As previously announced, Freeline and Bidco entered into an implementation agreement on November 22, 2023 to implement the Acquisition by means of a scheme of arrangement pursuant to Part 26 of the UK Companies Act 2006 (the "Sche

      2/12/24 12:00:00 PM ET
      $FRLN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $FRLN
    Leadership Updates

    Live Leadership Updates

    See more
    • Genespire appoints Dr. Sabah Sallah as Chief Medical Officer

      Genespire appoints Dr. Sabah Sallah as Chief Medical Officer Accomplished executive with extensive preclinical and clinical gene therapy experience joins Genespire to accelerate pipeline to the clinic Milan, Italy, 7 July 2022: Genespire, a next generation gene therapy company developing first-in-class transformative therapies with advanced lentiviral vectors, today announces the appointment of Dr. Sabah Sallah MD, PhD as Chief Medical Officer. Dr. Sallah will lead the Company's clinical strategy, development and operations as Genespire progresses its novel advanced lentiviral gene therapy platforms towards the clinic. Dr. Sallah is a board-certified hematologist who has spent more than

      7/7/22 2:00:00 AM ET
      $FRLN
      $QURE
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
      Biotechnology: Pharmaceutical Preparations
    • Freeline Appoints Paul Schneider as Chief Financial Officer

      LONDON, April 19, 2022 (GLOBE NEWSWIRE) -- Freeline Therapeutics Holdings plc (NASDAQ:FRLN) (the "Company" or "Freeline") today announced that Paul M. Schneider has been appointed Chief Financial Officer (CFO), effective May 16, 2022, based in Boston. Mr. Schneider joins Freeline from Exo Therapeutics, Inc., where he served as Senior Vice President, Finance and Operations. A seasoned financial executive with more than 20 years of leadership experience in large and small private and public biopharmaceutical companies, Mr. Schneider brings an impressive track record of financial stewardship, including corporate strategy and execution, financial planning, analysis and reporting, and investor

      4/19/22 8:01:00 AM ET
      $FRLN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Freeline Appoints Henning R. Stennicke, PhD, as Chief Scientific Officer to Lead Research and Discovery

      LONDON, Feb. 03, 2022 (GLOBE NEWSWIRE) -- Freeline Therapeutics Holdings plc (NASDAQ:FRLN) (the "Company" or "Freeline"), a clinical-stage biotechnology company developing transformative adeno-associated virus ("AAV") vector-mediated systemic gene therapies for people with inherited systemic debilitating diseases, today announced the expansion of its executive leadership team with the appointment of Henning R. Stennicke, PhD, as Chief Scientific Officer (CSO). Dr. Stennicke has been appointed to the role of CSO effective March 1, 2022. He will be based in Stevenage, UK, and report to Michael Parini, Freeline's Chief Executive Officer, as part of the executive leadership team. As CSO, Dr.

      2/3/22 7:00:00 AM ET
      $FRLN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $FRLN
    SEC Filings

    See more
    • SEC Form 15-12G filed by Freeline Therapeutics Holdings plc

      15-12G - Freeline Therapeutics Holdings plc (0001810031) (Filer)

      3/1/24 4:05:32 PM ET
      $FRLN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form EFFECT filed by Freeline Therapeutics Holdings plc

      EFFECT - Freeline Therapeutics Holdings plc (0001810031) (Filer)

      2/26/24 12:15:23 AM ET
      $FRLN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form S-8 POS filed by Freeline Therapeutics Holdings plc

      S-8 POS - Freeline Therapeutics Holdings plc (0001810031) (Filer)

      2/22/24 4:38:00 PM ET
      $FRLN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $FRLN
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    See more

    $FRLN
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    See more
    • SEC Form SC 13D/A filed by Freeline Therapeutics Holdings plc (Amendment)

      SC 13D/A - Freeline Therapeutics Holdings plc (0001810031) (Subject)

      2/22/24 4:06:06 PM ET
      $FRLN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form SC 13G/A filed by Freeline Therapeutics Holdings plc (Amendment)

      SC 13G/A - Freeline Therapeutics Holdings plc (0001810031) (Subject)

      2/14/24 12:15:26 PM ET
      $FRLN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form SC 13G/A filed by Freeline Therapeutics Holdings plc (Amendment)

      SC 13G/A - Freeline Therapeutics Holdings plc (0001810031) (Subject)

      2/12/24 4:24:07 PM ET
      $FRLN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Freeline Therapeutics downgraded by Morgan Stanley

      Morgan Stanley downgraded Freeline Therapeutics from Overweight to Equal-Weight

      2/1/22 7:44:12 AM ET
      $FRLN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Freeline Therapeutics upgraded by Redburn

      Redburn upgraded Freeline Therapeutics from Neutral to Buy

      1/7/22 7:43:23 AM ET
      $FRLN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • BTIG initiated coverage on Freeline Therapeutics with a new price target

      BTIG initiated coverage of Freeline Therapeutics with a rating of Buy and set a new price target of $10.00

      11/29/21 7:17:07 AM ET
      $FRLN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $FRLN
    Financials

    Live finance-specific insights

    See more
    • Freeline Reports Positive Initial Clinical Data from First Cohort of Phase 1/2 GALILEO-1 Trial of FLT201, Its Novel Gene Therapy Candidate, in Gaucher Disease

      Robust increases of up to 700-fold over baseline in plasma GCase enzyme activity in first two patients treated with FLT201 Normalization of leukocyte GCase in both patients demonstrates cellular uptake from plasma FLT201 has been well tolerated, with no serious adverse events Company to host conference call today at 8 a.m. ET LONDON, Oct. 04, 2023 (GLOBE NEWSWIRE) -- Freeline Therapeutics Holdings plc (NASDAQ:FRLN) today reported positive initial safety, tolerability and enzyme activity data from the ongoing Phase 1/2 GALILEO-1 trial evaluating FLT201, its adeno-associated virus (AAV) gene therapy candidate, in Gaucher disease. Gaucher disease is a debilitatin

      10/4/23 7:00:00 AM ET
      $FRLN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Freeline Reports Second Quarter 2023 Financial Results and Business Highlights

      Completed dosing in first cohort of Phase 1/2 GALILEO-1 trial of FLT201 in Gaucher disease; expect to report initial clinical data in third quarter of 2023 Extending impact of its novel GCase variant with research program for GBA1-linked Parkinson's disease Management to host conference call at 8:00 a.m. ET today LONDON, Aug. 15, 2023 (GLOBE NEWSWIRE) -- Freeline Therapeutics Holdings plc (NASDAQ:FRLN) today reported financial results for the second quarter of 2023 and provided a business update. "FLT201 is a potential first- and best-in-class gene therapy for Gaucher disease Type 1, the most common type of the disease," said Michael Parini, Chief Exec

      8/15/23 7:00:00 AM ET
      $FRLN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Freeline Therapeutics to Host Second Quarter 2023 Financial Results Call

      LONDON, Aug. 08, 2023 (GLOBE NEWSWIRE) -- Freeline Therapeutics Holdings plc (NASDAQ:FRLN) today announced that it will host a live conference call and webcast at 8:00 a.m. ET on Tuesday, August 15, 2023 to report its second quarter financial results and provide a corporate update. Participants may access this event via the teleconferencing numbers below and asking to join the Freeline call or through the webcast link here. Domestic: 1-866-524-3160International: 1-412-317-6760 While not required, it is recommended that participants join the call 10 minutes prior to the scheduled start. A live webcast of the call will also be available on the Investors section of Freeline's website at ww

      8/8/23 7:30:00 AM ET
      $FRLN
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care