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    SEC Form SC 13G filed by Mirati Therapeutics Inc.

    2/14/24 4:21:54 PM ET
    $MRTX
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $MRTX alert in real time by email
    SC 13G 1 tm242424d27_sc13g.htm SC 13G

     

     

    SCHEDULE 13G

     

    SECURITIES AND EXCHANGE COMMISSION
    WASHINGTON, DC 20549

     

    Under the Securities Exchange Act of 1934 

    (Amendment No. )*

     

    Mirati Therapeutics, Inc.

    (Name of Issuer)

     

    Common Stock, par value $0.001 per share

    (Title of Class of Securities)

     

      60468T105  
      (CUSIP Number)  
         
      December 31, 2023  
      (Date of Event which Requires Filing of this Statement)  

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

     

      x Rule 13d-1(b)

     

      ¨ Rule 13d-1(c)

     

      ¨ Rule 13d-1(d)

      

    *The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

     

    The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (the “Act”) or otherwise subject to the liabilities of that section of the Act, but shall be subject to all other provisions of the Act (however, see the Notes).

     

     

     

     

     

     

    CUSIP No.  60468T105

     

    1

    NAMES OF REPORTING PERSONS

     

    Baker Bros. Advisors LP

    2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions) 

    (a) ¨

    (b) ¨

    3

    SEC USE ONLY

     

    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON
    WITH

     

    5 

    SOLE VOTING POWER

     

    -0- (1)(2)

    6 

    SHARED VOTING POWER

     

    -0-

    7 

    SOLE DISPOSITIVE POWER

     

    -0- (1)(2)

    8 

    SHARED DISPOSITIVE POWER

     

    -0-

    9

     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    -0- (1)(2)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

    (See Instructions)

    ¨
    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    0.0% (1)(2)

    12

    TYPE OF REPORTING PERSON (See Instructions)

     

    IA, PN

     

      (1) At December 31, 2023, Baker Bros. Advisors LP beneficially owned 4,121,440 shares of Common Stock (“Common Stock”) of Mirati Therapeutics, Inc. (the “Issuer”) directly held by the Funds (as defined in Item 4) representing beneficial ownership of 5.9% based upon 70,147,706 shares of Common Stock outstanding as of November 1, 2023, as reported in the Issuer’s Form 10-Q filed with the Securities and Exchange Commission (“SEC”) on November 6, 2023.

     

      (2) As of the date of this filing, the Reporting Persons no longer beneficially own any securities of the Issuer as, effective January 23, 2024, the Issuer was acquired by a third party and and all of the securities of the Issuer were converted into the right to receive certain cash and other consideration.

     

     

     

     

    CUSIP No.  60468T105

     

    1

    NAMES OF REPORTING PERSONS

     

    Baker Bros. Advisors (GP) LLC

    2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions) 

    (a) ¨

    (b) ¨

    3

    SEC USE ONLY

     

    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    Delaware

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON
    WITH

     

    5 

    SOLE VOTING POWER

     

    -0- (1)(2)

    6 

    SHARED VOTING POWER

     

    -0-

    7 

    SOLE DISPOSITIVE POWER

     

    -0- (1)(2)

    8 

    SHARED DISPOSITIVE POWER

     

    -0-

    9

     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    -0- (1)(2)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

    (See Instructions)

    ¨
    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    0.0% (1)(2)

    12

    TYPE OF REPORTING PERSON (See Instructions)

     

    HC, OO

     

    (1)At December 31, 2023, Baker Bros. Advisors (GP) LLC beneficially owned 4,121,440 shares of Common Stock directly held by the Funds (as defined in Item 4) representing beneficial ownership of 5.9% based upon 70,147,706 shares of Common Stock outstanding as of November 1, 2023, as reported in the Issuer’s Form 10-Q filed with the SEC on November 6, 2023.

     

    (2)As of the date of this filing, the Reporting Persons no longer beneficially own any securities of the Issuer as, effective January 23, 2024, the Issuer was acquired by a third party and and all of the securities of the Issuer were converted into the right to receive certain cash and other consideration.

     

     

     

                     

    CUSIP No.  60468T105

     

    1

    NAMES OF REPORTING PERSONS

     

    Felix J. Baker

    2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions) 

    (a) ¨

    (b) ¨

    3 SEC USE ONLY 
    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    United States

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON
    WITH

     

    5 

    SOLE VOTING POWER

     

    -0- (1)(2)

    6 

    SHARED VOTING POWER

     

    -0-

    7 

    SOLE DISPOSITIVE POWER

     

    -0- (1)(2)

    8 

    SHARED DISPOSITIVE POWER

     

    -0-

    9

     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    -0- (1)(2)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

    (See Instructions)

    ¨
    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    0.0% (1)(2)

    12

    TYPE OF REPORTING PERSON (See Instructions)

     

    IN, HC

     

    (1)At December 31, 2023, Felix J. Baker beneficially owned 4,121,440 shares of Common Stock directly held by the Funds (as defined in Item 4) and 137 shares of Common Stock held directly by Felix J. Baker representing beneficial ownership of 5.9% based upon 70,147,706 shares of Common Stock outstanding as of November 1, 2023, as reported in the Issuer’s Form 10-Q filed with the SEC on November 6, 2023.

     

    (2)As of the date of this filing, the Reporting Persons no longer beneficially own any securities of the Issuer as, effective January 23, 2024, the Issuer was acquired by a third party and and all of the securities of the Issuer were converted into the right to receive certain cash and other consideration.

                   

     

     

     

    CUSIP No.  60468T105

     

    1

    NAMES OF REPORTING PERSONS

     

    Julian C. Baker

    2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions) 

    (a) ¨

    (b) ¨

    3

    SEC USE ONLY

     

    4

    CITIZENSHIP OR PLACE OF ORGANIZATION

     

    United States

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON
    WITH

     

    5 

    SOLE VOTING POWER

     

    -0- (1)(2)

    6 

    SHARED VOTING POWER

     

    -0-

    7 

    SOLE DISPOSITIVE POWER

     

    -0- (1)(2)

    8 

    SHARED DISPOSITIVE POWER

     

    -0-

    9

     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     

    -0- (1)(2)

    10

    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES

    (See Instructions)

    ¨
    11

    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

     

    0.0% (1)(2)

    12

    TYPE OF REPORTING PERSON (See Instructions)

     

    IN, HC

     

    (1)At December 31, 2023, Julian C. Baker beneficially owned 4,121,440 shares of Common Stock directly held by the Funds (as defined in Item 4) and 137 shares of Common Stock held directly by Julian C. Baker representing beneficial ownership of 5.9% based upon 70,147,706 shares of Common Stock outstanding as of November 1, 2023, as reported in the Issuer’s Form 10-Q filed with the SEC on November 6, 2023.

     

    (2)As of the date of this filing, the Reporting Persons no longer beneficially own any securities of the Issuer as, effective January 23, 2024, the Issuer was acquired by a third party and and all of the securities of the Issuer were converted into the right to receive certain cash and other consideration.

                 

     

     

     

    Schedule 13G

     

    Item 1(a) Name of Issuer:
       
      Mirati Therapeutics, Inc. (the “Issuer”)

     

    Item 1(b) Address of Issuer’s Principal Executive Offices:
       
      3545 Cray Court
       
      San Diego, Califormia 92121

     

    Item 2(a) Name of Person Filing:
       
      This Schedule 13G is being filed jointly by Baker Bros. Advisors LP (the “Adviser”), Baker Bros. Advisors (GP) LLC (the “Adviser GP”), Felix J. Baker and Julian C. Baker (collectively, the “Reporting Persons”).

     

    Item 2(b) Address of Principal Business Office or, if None, Residence:
       
      The business address of each of the Reporting Persons is:
       
      c/o Baker Bros. Advisors LP
       
      860 Washington Street, 3rd Floor
       
      New York, NY 10014
       
      (212) 339-5690

     

    Item 2(c) Citizenship:
       
      The Adviser is a limited partnership organized under the laws of the State of Delaware. The Adviser GP is a limited liability company organized under the laws of the State of Delaware. The citizenship of each of Julian C. Baker and Felix J. Baker is the United States of America.

     

    Item 2(d) Title of Class of Securities:
       
      Common Stock, par value $0.001 per share (“Common Stock”).

     

    Item 2(e) CUSIP Number:
       
      60468T105

     

     

     

     

    Item 3 If this statement is filed pursuant to §§240.13d-1(b) or (c), check whether the person filing is a:

     

    (a) ¨ Broker or dealer registered under Section 15 of the Exchange Act.

     

    (b) ¨ Bank as defined in section 3(a)(6) of the Exchange Act.

     

    (c) ¨ Insurance company as defined in section 3(a)(19) of the Exchange Act.

     

    (d) ¨ Investment company registered under section 8 of the Investment Company Act of 1940.

     

    (e) x An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E).

     

    (f) ¨ An employee benefit plan or endowment fund in accordance with Rule 13d-1(b)(1)(ii)(F).

     

    (g) x A parent holding company or control person in accordance with Rule 13d-1(b)(1)(ii)(G).

     

    (h) ¨ A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act.

     

    (i) ¨ A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940.

     

    (j) ¨ Group, in accordance with Rule 13d-1(b)(1)(ii)(J).

     

    Item 4 Ownership:

     

    Items 5 through 9 and 11 of each of the cover pages to this Schedule 13G are incorporated herein by reference. Set forth below is the aggregate number of shares of Common Stock directly held by each of Baker Brothers Life Sciences, L.P. (“Life Sciences”) and 667, L.P. (“667”, and together with Life Sciences, the “Funds”) which may be deemed to be indirectly beneficially owned by the Reporting Persons as of December 31, 2023.

     

    The information set forth below is based on 70,147,706 shares of Common Stock outstanding as of November 1, 2023, as reported in the Issuer’s Form 10-Q filed with the Securities and Exchange Commission on November 6, 2023. Such percentage figures are calculated in accordance with Rule 13d-3 under the Securities Exchange Act of 1934, as amended (the “Exchange Act”).

     

     

     

     

    Holder  Number of Shares of Common
    Stock we own or have the right
    to acquire within 60 days
       Percent of Class
    Outstanding
     
    667, L.P.   357,688    0.5%
    Baker Brothers Life Sciences, L.P.   3,763,752    5.4%
    Total   4,121,440    5.9%

     

    As of December 31, 2023, Julian C. Baker and Felix J. Baker each directly held 137 shares of Common Stock.

     

    As of the date of this filing, the Reporting Persons no longer beneficially own any securities of the Issuer as, effective January 23, 2024, the Issuer was acquired by a third party and and all of the securities of the Issuer were converted into the right to receive certain cash and other consideration.

     

    Name  Number of Shares of
    Common Stock we own
    or have the right to
    acquire within 60 days
       Percent of
    Class
    Outstanding
     
    667, L.P.   0    0.0%
    Baker Brothers Life Sciences, L.P.   0    0.0%
    Total   0    0.0%

     

    Pursuant to the management agreements, as amended, among the Adviser, the Funds and their respective general partners, the Funds’ respective general partners relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities previously held by the Funds, and thus the Adviser had complete and unlimited discretion and authority with respect to the Funds’ investments and voting power over investments.

     

    The Adviser GP is the sole general partner of the Adviser. The Adviser GP, Felix J. Baker and Julian C. Baker as managing members of the Adviser GP, and the Adviser may be deemed to have been beneficial owners of securities of the Issuer directly held by the Funds.

     

    Item 5 Ownership of Five Percent or Less of a Class:

     

    If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following x.

     

    Item 6 Ownership of More than Five Percent on Behalf of Another Person:

     

    N/A

     

     

     

     

    Item 7 Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person:

     

    The information in Item 4 is incorporated herein by reference.

     

    Item 8 Identification and Classification of Members of the Group:

     

    N/A

     

    Item 9 Notice of Dissolution of Group:

     

    N/A

     

    Item 10 Certification:

     

    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.

     

     

     

     

    SIGNATURE

     

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     

    February 14, 2024

     

     

    BAKER BROS. ADVISORS LP

     

    By: Baker Bros. Advisors (GP) LLC, its general partner

         
      By: /s/ Scott L. Lessing
        Name: Scott L. Lessing
    Title: President

     

      BAKER BROS. ADVISORS (GP) LLC
         
      By: /s/ Scott L. Lessing
        Name: Scott L. Lessing
    Title: President
         
        /s/ Julian C. Baker
        Julian C. Baker
         
        /s/ Felix J. Baker
        Felix J. Baker

     

     

     

     

     

     

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      Shares plans to initiate Phase 3 combination study evaluating adagrasib with pembrolizumab in first line non-small cell lung cancer in patients with TPS ≥ 50% Announces compelling initial clinical data for MRTX1719 in MTAP-deleted cancers demonstrating favorable safety profile and early signs of strong clinical activity David Meek to depart Company, Charles M. Baum, M.D., Ph.D., President and Founder, to assume role of interim CEO during search for permanent CEO Company will announce financial results for the second quarter 2023 along with recent corporate updates during a conference call at 5:30 p.m. ET / 2:30 p.m. PT SAN DIEGO, Aug. 8, 2023 /PRNewswire/ -- Mirati Therapeutics, Inc.® (NASD

      8/8/23 4:01:00 PM ET
      $MRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Mirati Therapeutics® to Report Second Quarter 2023 Financial Results and Recent Corporate Updates on August 8, 2023

      SAN DIEGO, July 25, 2023 /PRNewswire/ -- Mirati Therapeutics, Inc. (NASDAQ:MRTX), a commercial stage biotechnology company, will announce financial results for the second quarter 2023 along with recent corporate updates on August 8, 2023. During a conference call at 4:30 p.m. ET / 1:30 p.m. PT on August 8, company executives will provide company updates and review financial results. Investors and the general public are invited to listen to a live webcast of the call at the "Investors and Media" section on Mirati.com or by dialing the U.S. toll free +1 773-305-6853 or international +1 888-394-8218, confirmation code: 6674271. A replay of the call will be available approximately 2 hours after

      7/25/23 4:30:00 PM ET
      $MRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Mirati Therapeutics Reports First Quarter 2023 Financial Results and Recent Corporate Updates

      SAN DIEGO, May 9, 2023 /PRNewswire/ -- Mirati Therapeutics, Inc.® (NASDAQ:MRTX), a commercial stage biotechnology company, today announced financial results for the first quarter 2023 along with recent pipeline and corporate updates. "Today we are pleased to share the significant progress made during the first quarter of 2023, highlighted by our first full quarter of sales for KRAZATI®, which we believe is the best-in-class KRASG12C inhibitor. This is just the beginning of our journey with KRAZATI®, as we continue to advance our broad development plan in lung cancer and across other indications and lines of therapy," said David Meek, chief executive officer, Mirati Therapeutics, Inc. "In add

      5/9/23 4:01:00 PM ET
      $MRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $MRTX
    FDA approvals

    Live FDA approvals issued by the Food and Drug Administration and FDA breaking news

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    • FDA Approval for KRAZATI issued to MIRATI THERAPEUTICS, INC

      Submission status for MIRATI THERAPEUTICS, INC's drug KRAZATI (ORIG-1) with active ingredient ADAGRASIB has changed to 'Approval' on 12/12/2022. Application Category: NDA, Application Number: 216340, Application Classification: Type 1 - New Molecular Entity

      12/14/22 7:40:10 AM ET
      $MRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • FDA Approval for KRAZATI (ADAGRASIB) issued to MIRATI THERAPEUTICS, INC

      Submission status for MIRATI THERAPEUTICS, INC's drug KRAZATI (ADAGRASIB) (ORIG-1) with active ingredient ADAGRASIB has changed to 'Approval' on 12/12/2022. Application Category: NDA, Application Number: 216340, Application Classification: Type 1 - New Molecular Entity

      12/12/22 6:09:02 PM ET
      $MRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • FDA Approval for KRAZATI (ADAGRASIB) issued to MIRATI THERAPEUTICS, INC

      Submission status for MIRATI THERAPEUTICS, INC's drug KRAZATI (ADAGRASIB) (ORIG-1) with active ingredient ADAGRASIB has changed to 'Approval' on 12/12/2022. Application Category: NDA, Application Number: 216340, Application Classification: Efficacy

      12/12/22 4:56:01 PM ET
      $MRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $MRTX
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

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    • Mirati Therapeutics upgraded by Citigroup with a new price target

      Citigroup upgraded Mirati Therapeutics from Neutral to Buy and set a new price target of $48.00 from $51.00 previously

      8/10/23 7:25:39 AM ET
      $MRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Mirati Therapeutics upgraded by B. Riley Securities with a new price target

      B. Riley Securities upgraded Mirati Therapeutics from Neutral to Buy and set a new price target of $45.00

      8/9/23 8:29:32 AM ET
      $MRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Piper Sandler resumed coverage on Mirati Therapeutics with a new price target

      Piper Sandler resumed coverage of Mirati Therapeutics with a rating of Overweight and set a new price target of $45.00

      8/9/23 7:36:39 AM ET
      $MRTX
      Biotechnology: Pharmaceutical Preparations
      Health Care