• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • AI Executive AssistantNEW
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • AI Executive AssistantNEW
  • Settings
  • RSS Feeds
PublishGo to AppAI Helper
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlertsPublish with Us
    Company
    AboutQuantisnow PlusContactJobsAI employees for your businessNEW
    Legal
    Terms of usePrivacy policyCookie policy

    SEC Form SC 13G filed by Vor Biopharma Inc.

    10/27/22 4:47:08 PM ET
    $VOR
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $VOR alert in real time by email
    SC 13G 1 tm2229071d1_sc13g.htm SC 13G

     

      

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    Washington, D.C. 20549

     

     

    SCHEDULE 13G

    Under the Securities Exchange Act of 1934

    (Amendment No. ____)*

     

     

    Vor Biopharma Inc.

    (Name of Issuer)

     

    Common Stock, $0.0001 par value per share

    (Title of Class of Securities)

     

    929033108

    (CUSIP Number)

     

    October 17, 2022

    (Date of Event Which Requires Filing of this statement)

     

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

     

    ¨Rule 13d-1(b)

     

    xRule 13d-1(c)

     

    ¨Rule 13d-1(d)

     

    * The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

     

    The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

     

     

     

     

    Page 1 of 9 Pages 

     

     

     

    CUSIP No. 929033108

     

    1.Names of Reporting Persons

     

    Paradigm BioCapital Advisors LP

     

    2.Check the Appropriate Box if a Member of a Group (See Instructions)

     

    (a)  ¨

    (b)  x

     

    3.SEC Use Only

     

     

    4.Citizenship or Place of Organization

     

    Delaware

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON WITH:
    5.  SOLE VOTING POWER 2,328,494
    6.  SHARED VOTING POWER 0
    7.  SOLE DISPOSITIVE POWER 2,328,494
    8.  SHARED DISPOSITIVE POWER 0

      

    9.Aggregate Amount Beneficially Owned by Each Reporting Person

     

    2,328,494

     

    10.Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)  ¨

      

    11.Percent of Class Represented by Amount in Row (9)

     

    6.1%

     

    12.Type of Reporting Person (See Instructions)

     

    PN

     

     

    *       The information above is given as of the end of business on October 27, 2022, the filing date of this Schedule 13G.

     

     

    Page 2 of 9 Pages 

     

     

     

    CUSIP No. 929033108

     

    1.Names of Reporting Persons

     

    Paradigm BioCapital Advisors GP LLC

     

    2.Check the Appropriate Box if a Member of a Group (See Instructions)

     

    (a)   ¨

    (b)   x

     

    3.SEC Use Only

     

     

    4.Citizenship or Place of Organization

     

    Delaware

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON WITH:
    5.  SOLE VOTING POWER 2,328,494
    6.  SHARED VOTING POWER 0
    7.  SOLE DISPOSITIVE POWER 2,328,494
    8.  SHARED DISPOSITIVE POWER 0

     

    9.Aggregate Amount Beneficially Owned by Each Reporting Person

     

    2,328,494

     

    10.Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ¨

      

    11.Percent of Class Represented by Amount in Row (9)

     

    6.1%

     

    12.Type of Reporting Person (See Instructions)

     

    OO 

     

     

    *       The information above is given as of the end of business on October 27, 2022, the filing date of this Schedule 13G.

     

     

    Page 3 of 9 Pages 

     

     

     

    CUSIP No. 929033108

     

    1.Names of Reporting Persons

     

    Dr. Senai Asefaw

     

    2.Check the Appropriate Box if a Member of a Group (See Instructions)

     

    (a)   ¨

    (b)   x

     

    3.SEC Use Only

     

    4.Citizenship or Place of Organization

     

    USA

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON WITH:
    5.  SOLE VOTING POWER 2,328,494
    6.  SHARED VOTING POWER 0
    7.  SOLE DISPOSITIVE POWER 2,328,494
    8.  SHARED DISPOSITIVE POWER 0

      

    9.Aggregate Amount Beneficially Owned by Each Reporting Person

     

    2,328,494

      

    10.Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ¨

      

    11.Percent of Class Represented by Amount in Row (9)

     

    6.1%

     

    12.Type of Reporting Person (See Instructions)

     

    IN

     

     

    *       The information above is given as of the end of business on October 27, 2022, the filing date of this Schedule 13G.

     

     

    Page 4 of 9 Pages 

     

     

     

    CUSIP No. 929033108

     

    1.Names of Reporting Persons

     

    Paradigm BioCapital International Fund Ltd.

     

    2.Check the Appropriate Box if a Member of a Group (See Instructions)

     

    (a)  ¨

    (b)  x

     

    3.SEC Use Only

     

     

    4.Citizenship or Place of Organization

     

    Cayman Islands

     

    NUMBER OF
    SHARES
    BENEFICIALLY
    OWNED BY
    EACH
    REPORTING
    PERSON WITH:
    5.  SOLE VOTING POWER 1,678,049
    6.  SHARED VOTING POWER 0
    7.  SOLE DISPOSITIVE POWER 1,678,049
    8.  SHARED DISPOSITIVE POWER 0

     

    9.Aggregate Amount Beneficially Owned by Each Reporting Person

     

    1,678,049

     

    10.Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) ¨

      

    11.Percent of Class Represented by Amount in Row (9)

     

    4.4%

     

    12.Type of Reporting Person (See Instructions)

     

    CO

      

     

    *       The information above is given as of the end of business on October 27, 2022, the filing date of this Schedule 13G.

     

     

    Page 5 of 9 Pages 

     

     

      

    Item 1.

     

    (a) The name of the issuer is Vor Biopharma Inc. (the “Issuer”).

     

      (b) The principal executive offices of the Issuer are located at 100 Cambridge Park Drive, Suite 101,Cambridge, MA 02140.

     

    Item 2.

     

      (a) This Schedule 13G is filed by the following (the “Reporting Persons”): (1) Paradigm BioCapital Advisors LP (the “Adviser”); (2) Paradigm BioCapital Advisors GP LLC (the “GP”); (3) Dr. Senai Asefaw, and (4) Paradigm BioCapital International Fund Ltd. (the “Fund”). The Fund is a private investment vehicle. The Fund and a separately managed account managed by the Adviser (the “Account”) directly beneficially own the Common Stock (as defined below) reported in this Statement. The Adviser is the investment manager of the Fund and the Account. The GP is the general partner of the Adviser. Dr. Senai Asefaw is the managing member of the GP. The Adviser, the GP and Dr. Asefaw may be deemed to beneficially own the Common Stock directly beneficially owned by the Fund and the Account. Each Reporting Person disclaims beneficial ownership with respect to any Common Stock other than the Common Stock directly beneficially owned by such Reporting Person.

     

      (b) The principal business office of the Reporting Persons is 767 Third Avenue, 17th Floor, New York, NY 10017.

     

      (c) For citizenship information see Item 4 of the cover page of each Reporting Person.

     

      (d) This statement relates to the Common Stock, $0.0001 par value per share, of the Issuer (the “Common Stock”).

     

    (e) The CUSIP Number of the Common Stock is 929033108.

     

    Item 3. If this statement is filed pursuant to 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

     

    (a) o Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).
    (b) o Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).
    (c) o Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c).
    (d) o Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8).
    (e) o An investment adviser in accordance with 240.13d-1(b)(1)(ii)(E);
    (f) o An employee benefit plan or endowment fund in accordance with 240.13d-1(b)(1)(ii)(F);
    (g) o A parent holding company or control person in accordance with 240.13d-1(b)(1)(ii)(G);
    (h) o A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
    (i) o A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
    (j) o A non-U.S. institution in accordance with §240.13d-1(b)(1)(ii)(J);
    (k) o Group, in accordance with §240.13d-1(b)(1)(ii)(K).

     

     

    Page 6 of 9 Pages 

     

     

     

    If filing as a non-U.S. institution in accordance with §240.13d-1(b)(1)(ii)(J), please specify the type of institution: ___________________________

     

    Item 4. Ownership.

     

    See Items 5-9 and 11 on the cover page for each Reporting Person and Item 2, which information is given as of the close of business on October 27, 2022, the date of filing of this Schedule 13G. On the Event Date of October 17, 2022, the Reporting Persons collectively beneficially owned 2,078,518 shares of Common Stock, representing 5.5% of the outstanding shares of Common Stock.

    The percentages of beneficial ownership contained herein are based on 38,056,306 shares of Common Stock outstanding as of August 5, 2022, as reported in the Issuer’s Form 10-Q filed on August 11,2022.

     

    Item 5. Ownership of Five Percent or Less of a Class.

     

    If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following: ⃣

     

    Item 6. Ownership of More than Five Percent on Behalf of Another Person.

     

    Not applicable.

     

    Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company.

     

    Not applicable.

     

    Item 8. Identification and Classification of Members of the Group.

     

    Not applicable.

     

    Item 9. Notice of Dissolution of Group.

     

    Not applicable.

      

    Item 10. Certification.

     

    (a)       Not applicable.

     

    (b)       Not applicable.

     

    (c) By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under §240.14a-11.

     

     

    Page 7 of 9 Pages 

     

     

     

    SIGNATURE

     

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     

    Dated: October 27, 2022

     

    Paradigm BioCapital Advisors LP

    Paradigm BioCapital Advisors GP LLC

    Paradigm BioCapital International Fund Ltd.

     

     

    By:   /s/ David K. Kim  

    Name: David K. Kim

    Title: Authorized Signatory

      

     

     /s/ Dr. Senai Asefaw  

    Dr. Senai Asefaw

     

     

    Page 8 of 9 Pages 

     

     

     

    EXHIBIT INDEX

     

     

    Exhibit No. Document
       
    1 Joint Filing Agreement

     

     

    Page 9 of 9 Pages 

     

    Get the next $VOR alert in real time by email

    Crush Q3 2025 with the Best AI Executive Assistant

    Stay ahead of the competition with Tailforce.ai - your AI-powered business intelligence partner.

    AI-Powered Inbox
    Context-aware email replies
    Strategic Decision Support
    Get Started with Tailforce.ai

    Recent Analyst Ratings for
    $VOR

    DatePrice TargetRatingAnalyst
    6/30/2025$3.00Neutral → Buy
    H.C. Wainwright
    7/26/2022$18.00Outperform
    Wedbush
    4/27/2022$6.00Neutral
    Goldman
    12/17/2021$26.00Buy
    HC Wainwright & Co.
    12/3/2021$38.00Outperform
    Robert W. Baird
    12/3/2021$38.00Outperform
    Baird
    12/2/2021$30.00Outperform
    Oppenheimer
    10/19/2021$40.00Market Outperform
    JMP Securities
    More analyst ratings

    $VOR
    Press Releases

    Fastest customizable press release news feed in the world

    See more
    • Vor Bio Appoints Veteran Biotech Executive Sandy Mahatme as Chief Financial Officer and Chief Business Officer

      Mr. Mahatme brings decades of experience in strategic finance, capital formation, and operational leadership to support company's transformation and growth in autoimmune disease CAMBRIDGE, Mass., July 10, 2025 (GLOBE NEWSWIRE) -- Vor Bio (NASDAQ:VOR), a clinical-stage biotechnology company transforming the treatment of autoimmune diseases, today announced the appointment of Sandy Mahatme as Chief Financial Officer and Chief Business Officer, effective July 9, 2025. Mr. Mahatme joins Vor Bio with more than 30 years of executive leadership experience in the biopharmaceutical industry, with a strong track record in capital markets, business development, global operations, and shareholder va

      7/10/25 4:00:00 PM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Vor Bio Report Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

      CAMBRIDGE, Mass., July 01, 2025 (GLOBE NEWSWIRE) -- Vor Bio (NASDAQ:VOR), a clinical-stage biotechnology company transforming the treatment of autoimmune diseases, today announced that, effective as of June 26, 2025, the Board of Directors granted Jean-Paul Kress, the Company's Chief Executive Officer, an option to purchase 83,296,638 shares of Vor Bio's common stock in connection with the commencement of his employment. The foregoing stock option was granted as a material inducement to employment with Vor Bio in accordance with Nasdaq Listing Rule 5635(c)(4) and was granted under the Vor Biopharma Inc. 2023 Inducement Plan (the "Inducement Plan"). The stock option has a ten-year term and

      7/1/25 4:00:00 PM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • PureTech Founded Entity Vor Bio Announces Exclusive Global License Agreement with RemeGen for Late-Stage Autoimmune Asset and $175 Million Private Placement

      PureTech Health plc (NASDAQ:PRTC, LSE: PRTC)) ("PureTech" or the "Company"), a clinical-stage biotherapeutics company dedicated to changing the lives of patients with devastating diseases, noted that its Founded Entity, Vor Bio (NASDAQ:VOR), a clinical-stage biotechnology company transforming the treatment of autoimmune diseases, and RemeGen Co., Ltd. (HKEX: 9995, SHA: 688331) announced entry into an exclusive license agreement granting Vor Bio global rights (excluding China, Hong Kong, Macau and Taiwan) to develop and commercialize telitacicept, a novel dual-target fusion protein approved in China for generalized myasthenia gravis (gMG), systemic lupus erythematosus (SLE), and rheumatoid a

      6/26/25 2:00:00 AM ET
      $PRTC
      $VOR
      Biotechnology: Pharmaceutical Preparations
      Health Care
      Biotechnology: Biological Products (No Diagnostic Substances)

    $VOR
    SEC Filings

    See more
    • Vor Biopharma Inc. filed SEC Form 8-K: Regulation FD Disclosure

      8-K - Vor Biopharma Inc. (0001817229) (Filer)

      7/10/25 4:45:32 PM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form 144 filed by Vor Biopharma Inc.

      144 - Vor Biopharma Inc. (0001817229) (Subject)

      7/10/25 4:22:41 PM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Amendment: SEC Form SCHEDULE 13D/A filed by Vor Biopharma Inc.

      SCHEDULE 13D/A - Vor Biopharma Inc. (0001817229) (Subject)

      7/9/25 5:00:26 PM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $VOR
    Insider Purchases

    Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • Large owner Reprogrammed Interchange Llc bought 38,974,101 shares (SEC Form 4)

      4 - Vor Biopharma Inc. (0001817229) (Issuer)

      1/2/25 7:42:04 PM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $VOR
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • CFO Mahatme Sandesh was granted 13,882,750 shares (SEC Form 4)

      4 - Vor Biopharma Inc. (0001817229) (Issuer)

      7/10/25 4:51:30 PM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form 3 filed by new insider Mahatme Sandesh

      3 - Vor Biopharma Inc. (0001817229) (Issuer)

      7/10/25 4:49:09 PM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form 4 filed by CEO and Chairman Kress Jean-Paul

      4 - Vor Biopharma Inc. (0001817229) (Issuer)

      6/27/25 4:10:08 PM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $VOR
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    See more
    • Vor Biopharma upgraded by H.C. Wainwright with a new price target

      H.C. Wainwright upgraded Vor Biopharma from Neutral to Buy and set a new price target of $3.00

      6/30/25 7:56:45 AM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Wedbush initiated coverage on Vor Biopharma with a new price target

      Wedbush initiated coverage of Vor Biopharma with a rating of Outperform and set a new price target of $18.00

      7/26/22 8:25:46 AM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Goldman initiated coverage on Vor Biopharma with a new price target

      Goldman initiated coverage of Vor Biopharma with a rating of Neutral and set a new price target of $6.00

      4/27/22 6:14:19 AM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $VOR
    Leadership Updates

    Live Leadership Updates

    See more
    • Vor Bio Appoints Veteran Biotech Executive Sandy Mahatme as Chief Financial Officer and Chief Business Officer

      Mr. Mahatme brings decades of experience in strategic finance, capital formation, and operational leadership to support company's transformation and growth in autoimmune disease CAMBRIDGE, Mass., July 10, 2025 (GLOBE NEWSWIRE) -- Vor Bio (NASDAQ:VOR), a clinical-stage biotechnology company transforming the treatment of autoimmune diseases, today announced the appointment of Sandy Mahatme as Chief Financial Officer and Chief Business Officer, effective July 9, 2025. Mr. Mahatme joins Vor Bio with more than 30 years of executive leadership experience in the biopharmaceutical industry, with a strong track record in capital markets, business development, global operations, and shareholder va

      7/10/25 4:00:00 PM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Vor Bio Appoints Life Sciences and Technology Investor and Entrepreneur, Mr. Erez Kalir to its Board of Directors

      CAMBRIDGE, Mass., Jan. 08, 2025 (GLOBE NEWSWIRE) -- Vor Bio (NASDAQ:VOR), a clinical-stage cell and genome engineering company, today announced the appointment of Mr. Erez Kalir to its Board of Directors. The appointment represents a new seat on Vor Bio's Board of Directors, which has been created in connection with the recent private investment in public equity financing (PIPE) which was led by Reid Hoffman. Mr. Kalir will serve as the director designee of Reprogrammed Interchange, LLC, Mr. Hoffman's investment fund. Mr. Kalir brings a wealth of experience as an investor, entrepreneur, and thought leader with a deep focus on life sciences and technology. Currently the Managing Member of

      1/8/25 9:00:00 AM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Vor Bio Appoints Seasoned Healthcare Institutional Investor, Han Choi, M.D., LL.M., as Chief Financial Officer

      CAMBRIDGE, Mass., Sept. 30, 2024 (GLOBE NEWSWIRE) -- Vor Bio (NASDAQ:VOR), a clinical-stage cell and genome engineering company, today announced the appointment of Han Choi, M.D., LL.M., as its new Chief Financial Officer, effective immediately. Dr. Choi will join the Vor Bio leadership team and will report directly to the company's President and Chief Executive Officer, Dr. Robert Ang. Dr. Choi brings to Vor Bio over twenty-five years of experience in public and private investment management, business development, and corporate strategy within the pharmaceutical and biotechnology industry. His deep expertise in structuring corporate partnerships and investments, managing complex transact

      9/30/24 7:00:00 AM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $VOR
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    See more
    • Amendment: SEC Form SC 13G/A filed by Vor Biopharma Inc.

      SC 13G/A - Vor Biopharma Inc. (0001817229) (Subject)

      11/14/24 4:33:50 PM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form SC 13D/A filed by Vor Biopharma Inc. (Amendment)

      SC 13D/A - Vor Biopharma Inc. (0001817229) (Subject)

      2/14/24 4:17:24 PM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form SC 13G/A filed by Vor Biopharma Inc. (Amendment)

      SC 13G/A - Vor Biopharma Inc. (0001817229) (Subject)

      2/14/24 4:08:06 PM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $VOR
    Financials

    Live finance-specific insights

    See more
    • Vor Bio Announces Exploration of Strategic Alternatives to Maximize Shareholder Value

      CAMBRIDGE, Mass., May 08, 2025 (GLOBE NEWSWIRE) -- Vor Bio (NASDAQ:VOR), a clinical-stage cell and genome engineering company, today announced that, based on currently available clinical data from its key clinical programs and a challenging fundraising environment, the Board of Directors has approved the initiation of a process to explore a range of strategic alternatives aimed at maximizing both near- and long-term shareholder value.   These strategic alternatives could include, among other alternatives, a potential sale of assets of the Company, a potential licensing of assets of the Company, a sale of the Company, a business combination, a merger or other strategic action. The Company

      5/8/25 8:30:15 AM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Vor Bio Provides Clinical Update Further Validating Approach of Using Shielded Transplants to Deliver Targeted Therapies; Receives Supportive Feedback from FDA Regarding Registrational Trial Design

      Preliminary data suggests improved relapse-free survival compared to published groups of acute myeloid leukemia (AML) patients at high risk of relapse post-transplantTrem-cel + Mylotarg continue to demonstrate engraftment, shielding, and broadened therapeutic windowCompany has received supportive feedback from the FDA regarding a registrational clinical trial design CAMBRIDGE, Mass., Dec. 09, 2024 (GLOBE NEWSWIRE) -- Vor Bio (NASDAQ:VOR), a clinical-stage cell and genome engineering company, today announced updated clinical data from its ongoing Phase 1/2 VBP101 study of patients with relapsed/refractory AML receiving trem-cel followed by Mylotarg™. The data, which was presented in a post

      12/9/24 7:30:00 AM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • New Clinical Data Validates Vor Bio's Approach of Using Shielded Transplants to Deliver Targeted Therapies

      Trem-cel + Mylotarg demonstrated engraftment, shielding, broadened therapeutic window, and patient benefitVCAR33ALLO demonstrates encouraging biomarker data at lowest dose New asset VADC45 with significant potential opportunities across oncology, gene therapy, and autoimmune disorders CAMBRIDGE, Mass., Sept. 05, 2024 (GLOBE NEWSWIRE) -- Vor Bio (NASDAQ:VOR), a clinical-stage cell and genome engineering company, today announced new clinical data from its ongoing Phase 1/2 VBP101 study of patients with relapsed/refractory AML receiving trem-cel followed by Mylotarg™. The data demonstrated reliable engraftment, shielding from Mylotarg on-target toxicity, a broadened Mylotarg therapeutic wind

      9/5/24 4:01:00 PM ET
      $VOR
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care