• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
PublishDashboard
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlertsPublish with Us
    Company
    AboutQuantisnow PlusContactJobsAI employees
    Legal
    Terms of usePrivacy policyCookie policy

    SEC Form SC 13G/A filed by Synthetic Biologics Inc. (Amendment)

    2/23/22 4:42:27 PM ET
    $SYN
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $SYN alert in real time by email
    SC 13G/A 1 c103101_sc13ga.htm
         
      SECURITIES AND EXCHANGE
    COMMISSION
     
      Washington, D.C. 20549  

     

     

     

    SCHEDULE 13G

     

    (Rule 13d-102)

     

    INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT
    TO § 240.13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED

    PURSUANT TO § 240.13d-2.

     

    (Amendment No. 4)*

     

    Synthetic Biologics, Inc.

    (Name of Issuer)

     

    Common Stock, par value $0.001 per share

    (Title of Class of Securities)

     

    87164U102

    (CUSIP Number)

     

    December 31, 2021

    (Date of Event Which Requires Filing of this Statement)

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

    o Rule 13d-1(b)
    x Rule 13d-1(c)
    o Rule 13d-1(d)

     

     

     

    *The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

     

    The information required in the remainder of this cover page shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

     

     
     
     CUSIP No: 87164U102
      (1) Names of Reporting Persons
    Iroquois Capital Management L.L.C.
      (2) Check the Appropriate Box if a Member of a Group (See Instructions)
        (a) o
        (b) o
      (3) SEC Use Only
      (4) Citizenship or Place of Organization
    Delaware
    Number of
    Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    (5) Sole Voting Power
    0
     
    (6)

    Shared Voting Power
    272,500 shares of Common Stock
    908,195 shares of Common Stock issuable upon exercise of Warrants (See Item 4)

     

     
    (7) Sole Dispositive Power
    0
     
    (8)

    Shared Dispositive Power
    272,500 shares of Common Stock
    908,195 shares of Common Stock issuable upon exercise of Warrants (See Item 4)

     

      (9)

    Aggregate Amount Beneficially Owned by Each Reporting Person

     

    908,195 shares of Common Stock issuable upon exercise of Warrants (See Item 4)

     

      (10) Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) o
      (11) Percent of Class Represented by Amount in Row (9)
    0.89%
      (12) Type of Reporting Person (See Instructions)
    OO
     
     CUSIP No: 87164U102
      (1) Names of Reporting Persons
    Richard Abbe
      (2) Check the Appropriate Box if a Member of a Group (See Instructions)
        (a) o
        (b) o
      (3) SEC Use Only
      (4) Citizenship or Place of Organization
    United States of America
    Number of
    Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    (5) Sole Voting Power
    1,400,501 shares of Common Stock issuable upon exercise of Warrants (See Item 4)
     
    (6) Shared Voting Power
    272,500 shares of Common Stock
    908,195 shares of Common Stock issuable upon exercise of Warrants (See Item 4)
     
    (7) Sole Dispositive Power
    1,400,501 shares of Common Stock issuable upon exercise of Warrants (See Item 4)
     
    (8) Shared Dispositive Power
    272,500 shares of Common Stock
    908,195 shares of Common Stock issuable upon exercise of Warrants (See Item 4)
      (9) Aggregate Amount Beneficially Owned by Each Reporting Person
    272,500 shares of Common Stock
    2,308,696 shares of Common Stock issuable upon exercise of Warrants (See Item 4)*
      (10) Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) o
      (11) Percent of Class Represented by Amount in Row (9)
    1.92%
      (12) Type of Reporting Person (See Instructions)
    IN; HC
     
     CUSIP No: 87164U102
      (1) Names of Reporting Persons
    Kimberly Page
      (2) Check the Appropriate Box if a Member of a Group (See Instructions)
        (a) o
        (b) o
      (3) SEC Use Only
      (4) Citizenship or Place of Organization
    United States of America
    Number of
    Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    (5) Sole Voting Power
    0
     
    (6)

    Shared Voting Power
    272,500 shares of Common Stock
    908,195 shares of Common Stock issuable upon exercise of Warrants (See Item 4)

     

     
    (7) Sole Dispositive Power
    0
     
    (8)

    Shared Dispositive Power
    272,500 shares of Common Stock
    908,195 shares of Common Stock issuable upon exercise of Warrants (See Item 4)

     

     
      (9)

    Aggregate Amount Beneficially Owned by Each Reporting Person
    272,500 shares of Common Stock
    908,195 shares of Common Stock issuable upon exercise of Warrants (See Item 4)

     

      (10) Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) o
      (11) Percent of Class Represented by Amount in Row (9)
    0.89%
      (12) Type of Reporting Person (See Instructions)
    IN
     

    This Amendment No. 4 (this “Amendment”) amends the statement on Schedule 13G filed on October 18, 2018, as amended on February 14, 2019, February 14, 2020 and February 22, 2021 (the “Original Schedule 13G”) with respect to the Common Stock, $0.001 par value (the “Common Stock”) of Synthetic Biologics, Inc., a Nevada corporation (the “Company”). Capitalized terms used herein and not otherwise defined in this Amendment have the meanings set forth in the Original Schedule 13G. This Amendment amends and restates each of Item 4 and Item 5 in its entirety as set forth below.

     

    Item 4. Ownership

     

    Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1.

     

    The information as of the date of the event which requires filing of this statement required by Items 4(a) – (c) is set forth in Rows 5 – 11 of the cover page for each Reporting Person hereto and is incorporated herein by reference for each such Reporting Person. The percentage set forth in Row 11 of the cover page for each Reporting Person is based on 132,042,538 shares of Common Stock outstanding as of November 3, 2021, as reported in the Company's Quarterly Report on Form 10-Q for the quarterly period ended September 30, 2021 filed with the Securities and Exchange Commission on November 3, 2021, and assumes the exercise of the Company's reported warrants (the “Reported Warrants”), subject to the Blockers (as defined below).

     

    Pursuant to the terms of the Reported Warrants, the Reporting Persons cannot exercise the Reported Warrants to the extent the Reporting Persons would beneficially own, after any such exercise, more than 9.99% of the outstanding shares of Common Stock (the “Blockers”), and the percentage set forth in Row 11 of the cover page for each Reporting Person gives effect to the Blockers.

     

    As of the date of the event which requires filing of this statement, Iroquois Master Fund Ltd. (“Iroquois Master Fund”) held warrants to purchase 908,195 shares of Common Stock and Iroquois Capital Investment Group LLC (“ICIG”) held warrants to purchase 1,400,501 shares of Common Stock.

     

    Mr. Abbe shares authority and responsibility for the investments made on behalf of Iroquois Master Fund with Ms. Kimberly Page, each of whom is a director of the Iroquois Master Fund. As such, Mr. Abbe and Ms. Page may each be deemed to be the beneficial owner of all shares of Common Stock underlying the Reported Warrants (each subject to the Blockers) held by Iroquois Master Fund. Iroquois Capital is the investment advisor for Iroquois Master Fund and Mr. Abbe is the President of Iroquois Capital. Mr. Abbe has the sole authority and responsibility for the investments made on behalf of ICIG. As such, Mr. Abbe may be deemed to be the beneficial owner of all shares of Common Stock underlying the Reported Warrants (each subject to the Blockers) held by Iroquois Master Fund and ICIG. The foregoing should not be construed in and of itself as an admission by any Reporting Person as to beneficial ownership of shares of Common Stock owned by another Reporting Person. Each of the Reporting Persons hereby disclaims any beneficial ownership of any such shares of Common Stock except to the extent of their pecuniary interest therein.

     

    Item 5. Ownership of Five Percent or Less of a Class

     

    If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following:  x

     

    Item 10. Certification

     

    By signing below each of the undersigned certifies that, to the best of its knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.

     

    SIGNATURES

     

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     

    Date: February 22, 2022

     

      IROQUOIS CAPITAL MANAGEMENT L.L.C.  
         
      By:   /s/ Richard Abbe
     
     
      Richard Abbe, President  
         
        /s/ Richard Abbe
     
     
      Richard Abbe  
         
        /s/ Kimberly Page
     
     
      Kimberly Page  
     
    Get the next $SYN alert in real time by email

    Chat with this insight

    Save time and jump to the most important pieces.

    Recent Analyst Ratings for
    $SYN

    DatePrice TargetRatingAnalyst
    More analyst ratings

    $SYN
    Press Releases

    Fastest customizable press release news feed in the world

    See more
    • Mason Capital Management Highlights Corporate Governance Failures and Significant Shareholder Value Destruction Under Grifols Board of Directors

      Sends Letter to Board Detailing Board's Conflicts of Interest and History of Poor Capital Allocation Expresses Urgent Need for Independent Directors and Proper Oversight to Unlock Value Believes Rumored Brookfield Transaction Substantially Undervalues Grifols Mason Capital Management LLC ("Mason"), a registered investment advisor to funds and accounts holding approximately 2.1% of Grifols S.A. ("Grifols" or the "Company") (BME: GRF) (NASDAQ:GRFS) class A shares, today sent a letter to the Grifols Board of Directors (the "Board"). This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20241107873955/en/Historical Forward EV/EBITDA Multip

      11/8/24 3:54:00 PM ET
      $GRFS
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Synthetic Biologics Rebrands as Theriva Biologics

      ROCKVILLE, Md., Oct. 12, 2022 (GLOBE NEWSWIRE) -- Theriva Biologics, Inc. (NYSE:TOVX), ("Theriva" or the "Company") is the new name of Synthetic Biologics, Inc. (NYSE:SYN). The new name, logo and branding elements were introduced to better reflect Theriva's position as a clinical-stage pharmaceutical company developing a novel oncolytic adenovirus (OV) platform to address devastating cancers with high unmet need. In addition, the Company announced its common stock is expected to begin trading on NYSE American under the new ticker symbol "TOVX" on Thursday, October 13, 2022. "The rebranding solidifies our strategic transformation and reflects our sharpened focus on advancing unique, oncoly

      10/12/22 8:00:00 AM ET
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Synthetic Biologics Announces Positive Outcome of Data and Safety Monitoring Committee (DSMC) Review in Phase 1b/2a Clinical Trial of SYN-004 (ribaxamase) in Allogeneic Hematopoietic Cell Transplant Recipients

      - The DSMC has reviewed the safety and pharmacokinetic data from Cohort 1 and recommended that the study may proceed to enroll patients into Cohort 2 - ROCKVILLE, Md., Sept. 27, 2022 (GLOBE NEWSWIRE) -- Synthetic Biologics, Inc. (NYSE:SYN), a diversified clinical-stage company developing therapeutics designed to treat diseases in areas of high unmet need, today announced a positive outcome from the Data and Safety Monitoring Committee (DSMC) review of results from the first Cohort of its Phase 1b/2a randomized, double-blinded, placebo-controlled clinical trial of SYN-004 (ribaxamase) in allogeneic hematopoietic cell transplant (HCT) recipients for the prevention of acute graft-versus-host

      9/27/22 8:00:00 AM ET
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SYN
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • SEC Form 4 filed by Shallcross Steven A

      4 - Theriva Biologics, Inc. (0000894158) (Issuer)

      12/15/23 4:07:49 PM ET
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Wolf Jeffrey Alan

      4 - Theriva Biologics, Inc. (0000894158) (Issuer)

      12/15/23 4:01:42 PM ET
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Monahan John J

      4 - Theriva Biologics, Inc. (0000894158) (Issuer)

      12/15/23 4:00:19 PM ET
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SYN
    SEC Filings

    See more
    • Synthetic Biologics Inc. filed SEC Form 8-K: Regulation FD Disclosure, Other Events, Financial Statements and Exhibits

      8-K - Theriva Biologics, Inc. (0000894158) (Filer)

      2/7/24 8:10:24 AM ET
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Synthetic Biologics Inc. filed SEC Form 8-K: Regulation FD Disclosure, Financial Statements and Exhibits

      8-K - Theriva Biologics, Inc. (0000894158) (Filer)

      1/8/24 8:10:38 AM ET
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 10-Q filed by Synthetic Biologics Inc.

      10-Q - Theriva Biologics, Inc. (0000894158) (Filer)

      11/13/23 8:15:58 AM ET
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SYN
    Leadership Updates

    Live Leadership Updates

    See more
    • Mason Capital Management Highlights Corporate Governance Failures and Significant Shareholder Value Destruction Under Grifols Board of Directors

      Sends Letter to Board Detailing Board's Conflicts of Interest and History of Poor Capital Allocation Expresses Urgent Need for Independent Directors and Proper Oversight to Unlock Value Believes Rumored Brookfield Transaction Substantially Undervalues Grifols Mason Capital Management LLC ("Mason"), a registered investment advisor to funds and accounts holding approximately 2.1% of Grifols S.A. ("Grifols" or the "Company") (BME: GRF) (NASDAQ:GRFS) class A shares, today sent a letter to the Grifols Board of Directors (the "Board"). This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20241107873955/en/Historical Forward EV/EBITDA Multip

      11/8/24 3:54:00 PM ET
      $GRFS
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Synthetic Biologics Reports 2020 Year End Operational Highlights and Financial Results

      ROCKVILLE, Md., March 4, 2021 /PRNewswire/ -- Synthetic Biologics, Inc. (NYSE American: SYN), a diversified clinical-stage company leveraging the microbiome to develop therapeutics designed to prevent and treat gastrointestinal (GI) diseases in areas of high unmet need, today provided a clinical programs update and reported financial results for the year ended December 31, 2020. Recent developments: Received Institutional Review Board ("IRB") approval from Washington University School of Medicine in St. Louis for the SYN-004 (ribaxamase) Phase 1b/2a clinical trial protocol in allogeneic hematopoietic cell transplant ("HCT") recipients Commenced screening of patients for enrollment of the f

      3/4/21 4:10:00 PM ET
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SYN
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    See more
    • Synthetic Biologics upgraded by Maxim Group

      Maxim Group upgraded Synthetic Biologics from Hold to Buy

      3/12/21 10:41:11 AM ET
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SYN
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    See more
    • SEC Form SC 13G/A filed by Synthetic Biologics Inc. (Amendment)

      SC 13G/A - Synthetic Biologics, Inc. (0000894158) (Subject)

      2/23/22 4:42:27 PM ET
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G/A filed by Synthetic Biologics Inc. (Amendment)

      SC 13G/A - Synthetic Biologics, Inc. (0000894158) (Subject)

      2/4/22 4:23:58 PM ET
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13D/A filed

      SC 13D/A - Synthetic Biologics, Inc. (0000894158) (Subject)

      3/2/21 3:33:11 PM ET
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SYN
    Financials

    Live finance-specific insights

    See more
    • Synthetic Biologics Reports Second Quarter 2022 Operational Highlights and Financial Results

      -Prioritizing the advancement of novel oncolytic adenovirus (OV) platform- -Cash balance as of August 1, 2022 of $53.5 million, including the additional $3 million in gross proceeds from convertible preferred financing extends funding for business operations into Q1 2024- -Conference call and webcast to be held today at 8:30 a.m. ET- ROCKVILLE, Md., Aug. 11, 2022 (GLOBE NEWSWIRE) -- Synthetic Biologics, Inc. (NYSE:SYN), a diversified clinical-stage company developing therapeutics designed to treat diseases in areas of high unmet need, today reported financial results for the second quarter ended June 30, 2022, and provided a corporate update. "We are pleased with the steady progress th

      8/11/22 8:00:00 AM ET
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Synthetic Biologics to Host Conference Call and Webcast to Discuss Second Quarter 2022 Operational Highlights and Financial Results

      ROCKVILLE, Md., Aug. 04, 2022 (GLOBE NEWSWIRE) -- Synthetic Biologics, Inc. (NYSE:SYN), a diversified clinical-stage company developing therapeutics designed to treat diseases in areas of high unmet need, today announced that it plans to host a conference call on Thursday, August 11, 2022, at 8:30 a.m. ET to discuss its financial results for the quarter ended June 30, 2022 and provide a corporate update. Individuals may participate in the live call via telephone by dialing (800) 289-0571 (domestic) or (929) 477-0324 (international) and using the conference ID: 7145566. Participants are asked to dial in 15 minutes before the start of the call to register. Investors and the public can acces

      8/4/22 8:00:00 AM ET
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Synthetic Biologics Reports First Quarter 2022 Operational Highlights and Financial Results

      -Encouraging data further supports the development of novel oncolytic adenovirus (OV) platform; Announced a peer-reviewed publication highlighting positive clinical data on VCN-01 and an upcoming oral presentation on VCN-11, a novel oncolytic adenovirus designed to evade neutralizing antibodies- - Reported positive safety data on SYN-020 intestinal alkaline phosphatase from the Phase 1 Multiple Ascending Dose clinical trial- -Formed Scientific Advisory Board and strengthened the leadership team to support transformative clinical development strategy and extension into oncology - -As of March 31, 2022, Synthetic Biologics reports $56.7 million in cash, which is expected to provide runway

      5/16/22 8:00:00 AM ET
      $SYN
      Biotechnology: Pharmaceutical Preparations
      Health Care