Aprea Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops and commercializes cancer therapeutics that reactivate mutant p53 tumor suppressor protein. The company's lead product candidate is APR-246 (Eprenetapopt), a small molecule p53 reactivator that is in late-stage clinical development for the treatment of hematologic malignancies, including myelodysplastic syndromes (MDS) and acute myeloid leukemia, as well as for relapsed/refractory TP53 mutant chronic lymphoid leukemia; and gastric, bladder, and non-small cell lung cancers. It also develops APR-548, a p53 reactivator that is on Phase I dose-escalation clinical trial for oral administration in MDS patients. The company was founded in 2006 and is headquartered in Boston, Massachusetts.
IPO Year: 2019
Exchange: NASDAQ
Website: aprea.com
| Date | Price Target | Rating | Analyst |
|---|---|---|---|
| 8/20/2021 | Neutral → Underweight | JP Morgan | |
| 8/16/2021 | Buy → Hold | Berenberg | |
| 8/16/2021 | $6.00 → $4.00 | Neutral | HC Wainwright & Co. |
| 8/13/2021 | $6.00 → $5.00 | Sector Perform | RBC Capital |
| 8/13/2021 | $5.00 → $3.00 | Equal-Weight → Underweight | Morgan Stanley |
4 - Aprea Therapeutics, Inc. (0001781983) (Issuer)
4 - Aprea Therapeutics, Inc. (0001781983) (Issuer)
4 - Aprea Therapeutics, Inc. (0001781983) (Issuer)
4 - Aprea Therapeutics, Inc. (0001781983) (Issuer)
4 - Aprea Therapeutics, Inc. (0001781983) (Issuer)
4 - Aprea Therapeutics, Inc. (0001781983) (Issuer)
4 - Aprea Therapeutics, Inc. (0001781983) (Issuer)
4 - Aprea Therapeutics, Inc. (0001781983) (Issuer)
4 - Aprea Therapeutics, Inc. (0001781983) (Issuer)
4 - Aprea Therapeutics, Inc. (0001781983) (Issuer)
8-K - Aprea Therapeutics, Inc. (0001781983) (Filer)
SCHEDULE 13G/A - Aprea Therapeutics, Inc. (0001781983) (Subject)
10-Q - Aprea Therapeutics, Inc. (0001781983) (Filer)
8-K - Aprea Therapeutics, Inc. (0001781983) (Filer)
DEFA14A - Aprea Therapeutics, Inc. (0001781983) (Filer)
DEF 14A - Aprea Therapeutics, Inc. (0001781983) (Filer)
SCHEDULE 13G/A - Aprea Therapeutics, Inc. (0001781983) (Subject)
10-K - Aprea Therapeutics, Inc. (0001781983) (Filer)
8-K - Aprea Therapeutics, Inc. (0001781983) (Filer)
SCHEDULE 13G/A - Aprea Therapeutics, Inc. (0001781983) (Subject)
JP Morgan downgraded Aprea Therapeutics from Neutral to Underweight
Berenberg downgraded Aprea Therapeutics from Buy to Hold
HC Wainwright & Co. reiterated coverage of Aprea Therapeutics with a rating of Neutral and set a new price target of $4.00 from $6.00 previously
RBC Capital reiterated coverage of Aprea Therapeutics with a rating of Sector Perform and set a new price target of $5.00 from $6.00 previously
Morgan Stanley downgraded Aprea Therapeutics from Equal-Weight to Underweight and set a new price target of $3.00 from $5.00 previously
RBC Capital reiterated coverage of Aprea Therapeutics with a rating of Sector Perform and set a new price target of $8.00 from $10.00 previously