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    Amendment: SEC Form SC 13D/A filed by Tyra Biosciences Inc.

    11/19/24 9:31:34 PM ET
    $TYRA
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $TYRA alert in real time by email
    SC 13D/A 1 ff4142386_13da5-tyra.htm



    UNITED STATES
    SECURITIES AND EXCHANedgGE COMMISSION
    Washington, D.C. 20549
    SCHEDULE 13D
    (RULE 13D - 101)
    INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO 13d-1(a) AND
    AMENDMENTS THERETO FILED PURSUANT TO 13d-2(a)
    (Amendment No. 5)*
    Tyra Biosciences, Inc.
    (Name of Issuer)
    Common Stock, $0.0001 par value per share
    (Title of Class of Securities)

    90240B106
    (CUSIP Number)


    Josh La Grange
    Fried, Frank, Harris, Shriver & Jacobson LLP
    801 17th Street, NW, Washington, DC 20006
    202-639-7497
    (Name, Address and Telephone Number of Person
    Authorized to Receive Notices and Communications)


    November 15, 2024
    (Date of Event which Requires Filing of this Statement)
    If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box ☐.
    Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See §240.13d-7 for other parties to whom copies are to be sent.
    * The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.
    The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).


    CUSIP No. 90240B106
    1
    NAMES OF REPORTING PERSONS
     
     
     
    MVA Investors, LLC
     
     
     
     
    2
    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
    (a)
    ☐
     
    (b)
    ☒
     
     
    3
    SEC USE ONLY
     
     
     
     
     
     
     
    4
    SOURCE OF FUNDS (SEE INSTRUCTIONS)
     
     
     
    N/A
     
     
     
     
    5
    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(D) OR 2(E)
     
    ☐
     
     
     
     
     
    6
    CITIZENSHIP OR PLACE OF ORGANIZATION
     
     
     
    Delaware
     
     
     
     
    NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
    7
    SOLE VOTING POWER
     
     
     0
     
     
     
     
    8
    SHARED VOTING POWER
     
     
     
    43,939
     
     
     
     
    9
    SOLE DISPOSITIVE POWER
     
     
     0
     
     
     
     
    10
    SHARED DISPOSITIVE POWER
     
     
     
    43,939
     
     
     
     
    11
    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     
     
     
    43,939
     
     
     
     
    12
    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
     
    ☐
     
     
     
     
     
    13
    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
     
     
     
    0.1% *
     
     
     
     
    14
    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
     
     
     OO
     
     
     
     
    * Based on 52,603,228 shares of the Issuer’s Common Stock outstanding, which is (i) 50,602,991 shares of the Issuer’s Common Stock outstanding as of November 4, 2024 as set forth in the Issuer’s 10-Q filed with the Securities and Exchange Commission on November 7, 2024, plus (ii) 2,000,237 shares of Common Stock that may be acquired by the Reporting Persons within the next 60 days pursuant to warrants held by a fund managed by BCM, which warrants are subject to the Conversion Limit.

    CUSIP No. 90240B106
    1
    NAMES OF REPORTING PERSONS
     
     
     
    Aaron I. Davis
     
     
     
     
    2
    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
    (a)
    ☐
     
    (b)
    ☒
     
     
    3
    SEC USE ONLY
     
     
     
     
     
     
     
    4
    SOURCE OF FUNDS (SEE INSTRUCTIONS)
     
     
     
    N/A
     
     
     
     
    5
    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(D) OR 2(E)
     
    ☐
     

     
     
     
     
    6
    CITIZENSHIP OR PLACE OF ORGANIZATION
     
     

     
     
     
     
    NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
    7
    SOLE VOTING POWER
     
     
     0
     
     
     
     
    8
    SHARED VOTING POWER
     
     
     
    4,071,854
     
     
     
     
    9
    SOLE DISPOSITIVE POWER
     
     
     0
     
     
     
     
    10
    SHARED DISPOSITIVE POWER
     
     
     
    4,071,854
     
     
     
     
    11
    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     
     
     
    4,071,854
     
     
     
     
    12
    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
     
    ☐
     
     
     
     
     
    13
    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
     
     
     
    7.7% *
     
     
     
     
    14
    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
     
     
     IN
     
     
     
     
     
    * Based on 52,603,228 shares of the Issuer’s Common Stock outstanding, which is (i) 50,602,991 shares of the Issuer’s Common Stock outstanding as of November 4, 2024 as set forth in the Issuer’s 10-Q filed with the Securities and Exchange Commission on November 7, 2024, plus (ii) 2,000,237 shares of Common Stock that may be acquired by the Reporting Persons within the next 60 days pursuant to warrants held by a fund managed by BCM, which warrants are subject to the Conversion Limit.



    CUSIP No. 90240B106
    1
    NAMES OF REPORTING PERSONS
     
     
     
    Boxer Capital Management, LLC
     
     
     
     
    2
    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
    (a)
    ☐
     
    (b)
    ☒
     
     
    3
    SEC USE ONLY
     
     
     
     
     
     
     
    4
    SOURCE OF FUNDS (SEE INSTRUCTIONS)
     
     
     
    N/A
     
     
     
     
    5
    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(D) OR 2(E)
     
    ☐
     
     
     
     
     
    6
    CITIZENSHIP OR PLACE OF ORGANIZATION
     
     
     
    Delaware
     
     
     
     
    NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH
    7
    SOLE VOTING POWER
     
     
     0
     
     
     
     
    8
    SHARED VOTING POWER
     
     
     
    4,027,915
     
     
     
     
    9
    SOLE DISPOSITIVE POWER
     
     
     0
     
     
     
     
    10
    SHARED DISPOSITIVE POWER
     
     
     
    4,027,915
     
     
     
     
    11
    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
     
     
     
    4,027,915
     
     
     
     
    12
    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
     
    ☐
     
     
     
     
     
    13
    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
     
     
     
    7.7% *
     
     
     
     
    14
    TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
     
     
     
    OO, IA
     
     
     
     
     
    * Based on 52,603,228 shares of the Issuer’s Common Stock outstanding, which is (i) 50,602,991 shares of the Issuer’s Common Stock outstanding as of November 4, 2024 as set forth in the Issuer’s 10-Q filed with the Securities and Exchange Commission on November 7, 2024, plus (ii) 2,000,237 shares of Common Stock that may be acquired by the Reporting Persons within the next 60 days pursuant to warrants held by a fund managed by BCM, which warrants are subject to the Conversion Limit.


    This amendment (this “Amendment No. 5”) further amends and supplements the statement on Schedule 13D filed on September 24, 2021 (the “Original Filing”) by MVA Investors, LLC (“MVA Investors”), Aaron I. Davis and certain other persons with respect to the Common Stock, par value $0.0001 (the “Common Stock”) of Tyra Biosciences, Inc. (the “Issuer”), as previously amended on June 16, 2022 (“Amendment No. 1”), February 8, 2024 (“Amendment No. 2”), October 15, 2024 (“Amendment No. 3”), and October 22, 2024 (“Amendment No. 4”). In Amendment No. 3, Boxer Capital Management, LLC (“BCM”) adopted the Original Filing, as previously and then amended, as its statement on Schedule 13D with respect to the Common Stock. Capitalized terms used herein but not defined herein shall have the respective meanings defined in the Original Filing, as previously amended. The Original Filing, as previously amended, is further amended hereby only as specifically set forth herein, provided that with respect to any Item amended herein, if such Item is incorporated by reference into any other Item in the Original Filing, as previously amended, such incorporation by reference is also amended hereby.  For purposes of this Amendment No. 5, the “Reporting Persons” is defined collectively as BCM, MVA Investors and Mr. Davis.

    Item 2.
    Identity and Background.

    Item 2 is hereby amended to note that Siddarth Subramony resigned from the board of directors of Tyra Biosciences, Inc. on October 24, 2024.

    Item 4.
    Purpose of Transaction.

    Item 4 is hereby amended by the addition of the following:

    On November 8, 2024, Boxer Capital sold, for cash, 1,220,681 shares of Common Stock in a private sale transaction to an institutional buyer at a price per share of $16.25 pursuant to an agreement on customary terms (the “Stock Purchase Agreement”).

    On November 15, 2024, Boxer Capital sold, for cash, 1,200,000 shares of Common Stock in a private sale transaction to an institutional buyer at a price per share of $16.00 pursuant to an agreement on customary terms (together with the Stock Purchase Agreement, the “Purchase Agreements”).

    Item 5.
    Interest in Securities of the Issuer.

    Items 5(a) and (b) are hereby amended and restated to read as follows:

    (a) (b) For information regarding beneficial ownership, see the information presented on the cover pages.

    Item 5(c) is hereby amended by the addition of the following:

    (c) Except as set forth in Item 4 and in Schedule B with respect to BCM and MVA Investors, no transactions in the Issuer’s Common Stock were effected by the Reporting Persons since Amendment No. 4.





    Item 5(e) is hereby amended by the addition of the following:​

    On October 24, 2024, Siddarth Subramony resigned from the board of directors of Tyra Biosciences, Inc. and ceased to be a member of a group that beneficially owns more than 5% of the outstanding ​shares of Common Stock.

    Item 6.
    Contracts, Arrangements, Understandings or Relationships with Respect to Securities of the Issuer.


    Item 6 is hereby amended by the addition of the following:

    The disclosure set forth above in Item 4 regarding the Purchase Agreements is incorporated herein and is qualified by reference to the text thereof.

    Item 7.
    Material to be Filed as Exhibits.

    Item 7 is hereby amended by the addition of the following:

    Exhibit No.
    Description
    Exhibit 6
    Joint Filing Agreement, dated November 19, 2024 by and among Mr. Davis, MVA Investors and BCM.
    Exhibit 7
    Stock Purchase Agreement, dated November 8, 2024, among Boxer Capital, LLC and RA Capital Healthcare Fund, LP.
    Exhibit 8 Stock Purchase Agreement, dated November 15, 2024, among Boxer Capital, LLC and certain entities associated with Kyman Capital Management, LP.





    SIGNATURES
    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
    Dated:  November 19, 2024.
     
     
    AARON I. DAVIS 
     
         
     
     /s/ Aaron I. Davis  
      
    Aaron I. Davis, Individually
     
     
     
    MVA INVESTORS, LLC
     
     
     
    By:
     /s/ Aaron I. Davis  
     
     
    Name:
    Aaron I. Davis 
     
     
     
    Title:
    Authorized Signatory
     
         
     
    BOXER CAPITAL MANAGEMENT, LLC
     
     
     
    By:
     /s/ Aaron I. Davis  
     
     
    Name:
    Aaron I. Davis 
     
     
    Title:
    Managing Member



    JOINT FILING AGREEMENT
    PURSUANT TO RULE 13d-1(k)
     In accordance with Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of a Statement on Schedule 13D and any amendments to it with respect to Common Stock, $0.0001 par value per share, of Tyra Biosciences, Inc. and further agree that this Joint Filing Agreement be included as an Exhibit to those joint filings. Each of the undersigned agrees to be responsible for the timely filing of the Schedule 13D and any amendments thereto, and for the completeness and accuracy of the information concerning itself contained therein. This agreement may be executed in any number of counterparts, all of which taken together shall constitute one and the same instrument.
    Dated: November 19, 2024.
     
     
    AARON I. DAVIS 
     
         
     
     /s/ Aaron I. Davis  
      
    Aaron I. Davis, Individually
     
     
     
    MVA INVESTORS, LLC
     
     
     
    By:
     /s/ Aaron I. Davis  
     
     
    Name:
    Aaron I. Davis 
     
     
     
    Title:
    Authorized Signatory
     
         
     
    BOXER CAPITAL MANAGEMENT, LLC
     
     
     
    By:
     /s/ Aaron I. Davis  
     
     
    Name:
    Aaron I. Davis 
     
     
    Title:
    Managing Member






    SCHEDULE B

    Table I: Boxer Capital Management, LLC

                                   
      
    Date
     
      
    Shares
     
      
    Price per
    Share
     
      
    Transaction Type
     
                     
      
     
    10/28/2024
     
      
     
    175,000
     
      
    $
    20.55
       *
     
    Open Market Sale
     
                     
      
     
    10/29/2024
     
      
     
    125,000
     
      
    $
    17.52
       *
     
    Open Market Sale
     
                     
      
     
    10/30/2024
     
      
     
    25,000
     
      
    $
    15.78
       *
     
    Open Market Sale
     
                     
      
     
    10/31/2024
     
      
     
    200,000
     
      
    $
    16.55
       *
     
    Open Market Sale
     
                     
      
     
    11/01/2024
     
      
     
    65,000
     
      
    $
    16.43
       *
     
    Open Market Sale
     
                     
      
     
    11/04/2024
     
      
     
    20,000
     
      
    $
    16.39
       *
     
    Open Market Sale
     
                     
      
     
    11/05/2024
     
      
     
    35,000
     
      
    $
    16.66
       *
     
    Open Market Sale
     
                     
       
    11/06/2024
     
      
     
    60,000
     
      
    $
    17.12
       *
     
    Open Market Sale
                       
      
     
    10/28/2024
     
      
     
    175,008
     
      
    $
    0.001
     
      
     
    Cashless Exercise (net 175,000 shares)
     
                     
      
     
    10/29/2024
     
      
     
    125,007
     
      
    $
    0.001
     
      
     
    Cashless Exercise (net 125,000 shares)
     
                     
      
     
    10/30/2024
     
      
     
    25,002
     
      
    $
    0.001
     
      
     
    Cashless Exercise (net 25,000 shares)
     
                     
      
     
    10/31/2024
     
      
     
    200,013
     
      
    $
    0.001
     
      
     
    Cashless Exercise (net 200,000 shares)
     
                     
      
     
    11/01/2024
     
      
     
    65,004
     
      
    $
    0.001
     
      
     
    Cashless Exercise (net 65,000 shares)
     
                     
      
     
    11/04/2024
     
      
     
    20,002
     
      
    $
    0.001
     
      
     
    Cashless Exercise (net 20,000 shares)
     
                     
      
     
    11/05/2024
     
      
     
    35,003
     
      
    $
    0.001
     
      
     
    Cashless Exercise (net 35,000 shares)
     
                     
      
     
    11/06/2024
     
      
     
    60,004
     
      
    $
    0.001
     
      
     
    Cashless Exercise (net 60,000 shares)
     
                     
      
     
                                                 
    * The price reported is a weighted average price. These shares were sold in multiple transactions.

    Table II: MVA Investors, LLC

                                   
      
    Date
     
      
    Shares
     
      
    Price per
    Share
     
      
    Transaction Type
     
                     
      
     
    10/28/2024
     
      
     
    20,000
     
      
    $
    20.63
       *
     
    Open Market Sale
     
                     
      
     
    10/29/2024
     
      
     
    10,000
     
      
    $
    17.38
       *
     
    Open Market Sale
     
                     
      
     
    10/30/2024
     
      
     
    2,000
     
      
    $
    15.69
       *
     
    Open Market Sale
     
                     
      
     
    10/31/2024
     
      
     
    10,000
     
      
    $
    16.31
       *
     
    Open Market Sale
     
                     

























    * The price reported is a weighted average price. These shares were sold in multiple transactions.
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    • SEC Form 8-K filed by Tyra Biosciences Inc.

      8-K - Tyra Biosciences, Inc. (0001863127) (Filer)

      6/30/25 8:07:00 AM ET
      $TYRA
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 144 filed by Tyra Biosciences Inc.

      144 - Tyra Biosciences, Inc. (0001863127) (Subject)

      6/18/25 4:03:27 PM ET
      $TYRA
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 144 filed by Tyra Biosciences Inc.

      144 - Tyra Biosciences, Inc. (0001863127) (Subject)

      6/17/25 4:21:17 PM ET
      $TYRA
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $TYRA
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

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    • Piper Sandler resumed coverage on Tyra Biosciences with a new price target

      Piper Sandler resumed coverage of Tyra Biosciences with a rating of Overweight and set a new price target of $33.00

      5/21/25 9:01:58 AM ET
      $TYRA
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • UBS initiated coverage on Tyra Biosciences with a new price target

      UBS initiated coverage of Tyra Biosciences with a rating of Buy and set a new price target of $28.00

      1/7/25 8:31:57 AM ET
      $TYRA
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Tyra Biosciences upgraded by BofA Securities with a new price target

      BofA Securities upgraded Tyra Biosciences from Neutral to Buy and set a new price target of $31.00 from $22.00 previously

      10/18/24 7:41:59 AM ET
      $TYRA
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $TYRA
    Large Ownership Changes

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    • Amendment: SEC Form SC 13D/A filed by Tyra Biosciences Inc.

      SC 13D/A - Tyra Biosciences, Inc. (0001863127) (Subject)

      12/6/24 9:30:49 PM ET
      $TYRA
      Biotechnology: Pharmaceutical Preparations
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    • Amendment: SEC Form SC 13D/A filed by Tyra Biosciences Inc.

      SC 13D/A - Tyra Biosciences, Inc. (0001863127) (Subject)

      11/19/24 9:31:34 PM ET
      $TYRA
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Amendment: SEC Form SC 13G/A filed by Tyra Biosciences Inc.

      SC 13G/A - Tyra Biosciences, Inc. (0001863127) (Subject)

      11/14/24 5:47:01 PM ET
      $TYRA
      Biotechnology: Pharmaceutical Preparations
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    $TYRA
    Financials

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    • Tyra Biosciences Reports Interim Clinical Proof-of-Concept Data for TYRA-300, an Investigational Oral FGFR3-Selective Inhibitor, in Phase 1/2 SURF301 Study in Patients with Metastatic Urothelial Cancer (mUC)

      - Encouraging preliminary anti-tumor activity observed in heavily pre-treated population - - At ≥ 90 mg QD, 6 out of 11 (54.5%) patients with FGFR3+ mUC achieved a confirmed partial response (PR), with 100% disease control rate and sustained duration of activity - - Positive safety results across all QD doses, with infrequent FGFR2/FGFR1-associated toxicities - - Conference call scheduled for October 25th, 2024, at 8AM EDT - CARLSBAD, Calif., Oct. 24, 2024 /PRNewswire/ -- Tyra Biosciences, Inc. (NASDAQ:TYRA), a clinical-stage biotechnology company focused on developing next-generation precision medicines that target large opportunities in Fibroblast Growth Factor Receptor (FGFR) biology, ann

      10/24/24 6:21:00 PM ET
      $TYRA
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Tyra Biosciences to Host Conference Call on Interim Clinical Data of TYRA-300 from SURF301 Phase 1/2 Study on October 25, 2024, at 8am ET

      CARLSBAD, Calif., Oct. 23, 2024 /PRNewswire/ -- Tyra Biosciences, Inc. (NASDAQ:TYRA), a clinical-stage biotechnology company focused on developing next-generation precision medicines that target large opportunities in Fibroblast Growth Factor Receptor (FGFR) biology, today announced that it will host a conference call and webcast on October 25, 2024 at 8:00 am ET to share interim clinical results of TYRA-300 from the SURF301 Phase 1/2 study in metastatic urothelial cancer (mUC). These data will be presented in a late-breaking oral presentation at the 36th EORTC-NCI-AACR (ENA) Symposium on Molecular Targets and Cancer Therapeutics, being held October 23-25, 2024, in Barcelona, Spain. Gary Ste

      10/23/24 4:05:00 PM ET
      $TYRA
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Tyra Biosciences Expands Development of TYRA-300, an Oral FGFR3 Selective Agent, into Achondroplasia

      - In preclinical models, TYRA-300 demonstrated significant increases in growth and bone length- -Phase 2 clinical study for pediatric achondroplasia planned to be initiated in 2024--Conference call and webcast today, March 1st, at 8:00 am ET- CARLSBAD, Calif., March 1, 2023 /PRNewswire/ -- Tyra Biosciences, Inc. (NASDAQ:TYRA), a clinical-stage biotechnology company focused on developing next-generation precision medicines that target large opportunities in Fibroblast Growth Factor Receptors (FGFR) biology, today announced that it is expanding development of TYRA-300 into achondroplasia (ACH) based on positive preclinical results demonstrated in a study performed in collaboration with the Ima

      3/1/23 7:00:00 AM ET
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      Biotechnology: Pharmaceutical Preparations
      Health Care

    $TYRA
    Leadership Updates

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    • Tyra Biosciences Announces Appointment of Adele Gulfo to Board of Directors

      CARLSBAD, Calif., Jan. 29, 2025 /PRNewswire/ -- Tyra Biosciences, Inc. (NASDAQ:TYRA), a clinical-stage biotechnology company focused on developing next-generation precision medicines that target large opportunities in Fibroblast Growth Factor Receptor (FGFR) biology, announced today the appointment of Adele Gulfo to its Board of Directors. Ms. Gulfo brings nearly three decades of executive leadership experience to the TYRA board, with a strong track record in developing and commercializing some of the world's best-selling medicines at Pfizer, AstraZeneca, Viatris and Sumitomo Pharma. "Adele is one of the most accomplished drug developers in our industry, with nearly thirty years of global ex

      1/29/25 4:05:00 PM ET
      $TYRA
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Tyra Biosciences Receives IND Clearance from FDA to Proceed with Phase 2 Study of TYRA-300 in Non-Muscle Invasive Bladder Cancer (SURF302)

      -TYRA appoints urologic oncologist, Erik Goluboff, M.D., as SVP, Clinical Development to lead NMIBC- -First patient expected to be dosed in SURF302 in Q2 2025- CARLSBAD, Calif., Jan. 10, 2025 /PRNewswire/ -- Tyra Biosciences, Inc. (NASDAQ:TYRA), a clinical-stage biotechnology company focused on developing next-generation precision medicines that target large opportunities in Fibroblast Growth Factor Receptor (FGFR) biology, announced today that the U.S. Food and Drug Administration (FDA) cleared its Investigational New Drug (IND) application for TYRA-300 allowing the company to proceed with a Phase 2 clinical trial of TYRA-300 in low-grade, intermediate risk non-muscle invasive bladder cance

      1/10/25 8:00:00 AM ET
      $TYRA
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Tyra Biosciences Reports Third Quarter 2024 Financial Results and Highlights

      - Reported positive interim clinical proof-of-concept results for TYRA-300 in mUC from SURF301 Ph1/2 study - - IND cleared for Phase 2 study of TYRA-300 in pediatric achondroplasia (BEACH301) - - Strengthened leadership with appointment of Doug Warner, MD as Chief Medical Officer - - Cash, cash equivalents, and marketable securities of $360.1 million at Q3 2024 - CARLSBAD, Calif., Nov. 7, 2024 /PRNewswire/ -- Tyra Biosciences, Inc. (NASDAQ:TYRA), a clinical-stage biotechnology company focused on developing next-generation precision medicines that target large opportunities in Fibroblast Growth Factor Receptor (FGFR) biology, today reported financial results for the quarter ended September 30

      11/7/24 4:05:00 PM ET
      $TYRA
      Biotechnology: Pharmaceutical Preparations
      Health Care