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    Amendment: SEC Form SC 13G/A filed by Tyra Biosciences Inc.

    11/14/24 5:47:01 PM ET
    $TYRA
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $TYRA alert in real time by email
    SC 13G/A 1 tm2427660d2_sc13ga.htm SC 13G/A

     

     

     

      UNITED STATES  
      SECURITIES AND EXCHANGE COMMISSION  
      Washington, D.C. 20549  

     

    SCHEDULE 13G

     

    Under the Securities Exchange Act of 1934

    (Amendment No. 1)*

     

    Tyra Biosciences, Inc.

    (Name of Issuer)

     

    Common Stock, par value $0.0001 per share

    (Title of Class of Securities)

     

    90240B106

    (CUSIP Number)

     

    September 30, 2024

    (Date of Event Which Requires Filing of this Statement)

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

     

    ¨ Rule 13d-1(b)
    x Rule 13d-1(c)
    ¨ Rule 13d-1(d)

     

    *The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

     

    The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

     

     

     

     

     

     

    CUSIP No.  90240B106
     
      1. Names of Reporting Persons
    Nextech VI Oncology SCSp
     
      2. Check the Appropriate Box if a Member of a Group (See Instructions)
        (a) ¨
        (b) x(1)
     
      3. SEC Use Only
     
      4. Citizenship or Place of Organization
    Luxembourg
         
    Number of
    Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    5. Sole Voting Power
    4,055,861 shares
     
    6. Shared Voting Power
     0
     
    7. Sole Dispositive Power
     4,055,861 shares
     
    8. Shared Dispositive Power
    0
     
      9. Aggregate Amount Beneficially Owned by Each Reporting Person
    4,055,861 shares
     
      10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)  ¨
     
      11. Percent of Class Represented by Amount in Row (9)
    7.7% (2)
     
      12. Type of Reporting Person (See Instructions)
    PN
               

     

    (1)This Schedule 13G is filed by Nextech VI Oncology SCSp (“Nextech VI LP”), Nextech VI GP S.à r.l. (“Nextech VI GP”), Ian Charoub (“Charoub”), Costas Constantinides (“Constantinides”) and Rocco Sgobbo (“Sgobbo” and, with Nextech VI LP, Nextech VI GP, Charoub and Constantinides, collectively, the “Reporting Persons”). The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.
    (2)The percent of class was calculated based on 52,806,137 shares of Common Stock outstanding as of August 5, 2024, as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 7, 2024.

     

    2

     

     

    CUSIP No.  90240B106
     
      1. Names of Reporting Persons
    Nextech VI GP S.à r.l.
     
      2. Check the Appropriate Box if a Member of a Group (See Instructions)
        (a) ¨
        (b) x(1)
     
      3. SEC Use Only
     
      4. Citizenship or Place of Organization
    Luxembourg
         
    Number of
    Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    5. Sole Voting Power
    4,055,861 shares
     
    6. Shared Voting Power
     0
     
    7. Sole Dispositive Power
     4,055,861 shares
     
    8. Shared Dispositive Power
    0
     
      9. Aggregate Amount Beneficially Owned by Each Reporting Person
    4,055,861 shares
     
      10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)  ¨
     
      11. Percent of Class Represented by Amount in Row (9)
    7.7% (2)
     
      12. Type of Reporting Person (See Instructions)
    OO
               

     

    (1)This Schedule 13G is filed by the Reporting Persons. The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.
    (2)The percent of class was calculated based on 52,806,137 shares of Common Stock outstanding as of August 5, 2024, as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 7, 2024.

     

    3

     

     

    CUSIP No.  90240B106
     
      1. Names of Reporting Persons
    Ian Charoub
     
      2. Check the Appropriate Box if a Member of a Group (See Instructions)
        (a) ¨
        (b) x (1)
     
      3. SEC Use Only
     
      4. Citizenship or Place of Organization
    Sweden
         
    Number of
    Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    5. Sole Voting Power
    0
     
    6. Shared Voting Power
     4,055,861 shares
     
    7. Sole Dispositive Power
     0
     
    8. Shared Dispositive Power
    4,055,861 shares
     
      9. Aggregate Amount Beneficially Owned by Each Reporting Person
    4,055,861 shares
     
      10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)  ¨
     
      11. Percent of Class Represented by Amount in Row (9)
    7.7% (2)
     
      12. Type of Reporting Person (See Instructions)
    IN
               

     

    (1)This Schedule 13G is filed by the Reporting Persons. The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.
    (2)The percent of class was calculated based on 52,806,137 shares of Common Stock outstanding as of August 5, 2024, as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 7, 2024.

     

    4

     

     

    CUSIP No.  90240B106
     
      1. Names of Reporting Persons
    Costas Constantinides
     
      2. Check the Appropriate Box if a Member of a Group (See Instructions)
        (a) ¨
        (b) x (1)
     
      3. SEC Use Only
     
      4. Citizenship or Place of Organization
    Cyprus
         
    Number of
    Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    5. Sole Voting Power
    0
     
    6. Shared Voting Power
     4,055,861 shares
     
    7. Sole Dispositive Power
     0
     
    8. Shared Dispositive Power
    4,055,861 shares
     
      9. Aggregate Amount Beneficially Owned by Each Reporting Person
    4,055,861 shares
     
      10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)  ¨
     
      11. Percent of Class Represented by Amount in Row (9)
    7.7% (2)
     
      12. Type of Reporting Person (See Instructions)
    IN
               

     

    (1)This Schedule 13G is filed by the Reporting Persons. The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.
    (2)The percent of class was calculated based on 52,806,137 shares of Common Stock outstanding as of August 5, 2024, as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 7, 2024.

     

    5

     

     

    CUSIP No.  90240B106
     
      1. Names of Reporting Persons
    Rocco Sgobbo
     
      2. Check the Appropriate Box if a Member of a Group (See Instructions)
        (a) ¨
        (b) x (1)
     
      3. SEC Use Only
     
      4. Citizenship or Place of Organization
    Switzerland
         
    Number of
    Shares
    Beneficially
    Owned by
    Each
    Reporting
    Person With
    5. Sole Voting Power
    0
     
    6. Shared Voting Power
     4,055,861 shares
     
    7. Sole Dispositive Power
     0
     
    8. Shared Dispositive Power
    4,055,861 shares
     
      9. Aggregate Amount Beneficially Owned by Each Reporting Person
    4,055,861 shares
     
      10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)  ¨
     
      11. Percent of Class Represented by Amount in Row (9)
    7.7% (2)
     
      12. Type of Reporting Person (See Instructions)
    IN
               

     

    (1)This Schedule 13G is filed by the Reporting Persons. The Reporting Persons expressly disclaim status as a “group” for purposes of this Schedule 13G.
    (2)The percent of class was calculated based on 52,806,137 shares of Common Stock outstanding as of August 5, 2024, as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 7, 2024.

     

    6

     

     

    Item 1.
      (a)

    Name of Issuer:

     

    Tyra Biosciences, Inc.

      (b)

    Address of Issuer’s Principal Executive Offices:

     

    2656 State Street
    Carlsbad, California 92008

     

    Item 2.
      (a)

    Name of Reporting Persons Filing:

     

    Nextech VI Oncology SCSp (“Nextech VI LP”)

    Nextech VI GP S.à r.l. (“Nextech VI GP”)

    Ian Charoub (“Charoub”)

    Costas Constantinides (“Constantinides”)

    Rocco Sgobbo (“Sgobbo”)

      (b)

    Address of Principal Business Office or, if none, Residence:  

     

    8 rue Lou Hemmer

    L-1748 Luxembourg-Findel

    Grand-Duché de Luxembourg

      (c)Citizenship      
               
        Entities: Nextech VI Oncology SCSp - Luxembourg
          Nextech VI GP S.à r.l. - Luxembourg
               
        Individuals: Ian Charoub - Sweden
          Costas Constantinides - Cyprus
          Rocco Sgobbo - Switzerland

      (d)

    Title of Class of Securities:

     

    Common Stock, par value $0.0001 per share

      (e)

    CUSIP Number:

     

    90240B106

     
    Item 3. If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
      Not applicable

     

    7

     

     

    Item 4. Ownership
       
    Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1 as of November 14, 2024:

     

    Reporting Persons  Shares Held
    Directly
      Sole
    Voting
    Power
      Shared
    Voting
    Power (1)
      Sole
    Dispositive
    Power
      Shared
    Dispositive
    Power (1)
      Beneficial
    Ownership
      Percentage
    of Class (1) (2)
     
    Nextech VI LP   4,055,861   4,055,861   0   4,055,861   0   4,055,861   7.7%
    Nextech VI GP (1)   0   4,055,861   0   4,055,861   0   4,055,861   7.7%
    Charoub (1)   0   0   4,055,861   0   4,055,861   4,055,861   7.7%
    Constantinides (1)   0   0   4,055,861   0   4,055,861   4,055,861   7.7%
    Sgobbo (1)   0   0   4,055,861   0   4,055,861   4,055,861   7.7%

     

    (1)    The shares are held by Nextech VI LP. Nextech VI GP serves as the sole general partner of Nextech VI LP and has sole voting and investment control over the shares owned by Nextech VI LP and may be deemed to own beneficially the shares held by Nextech VI LP. Nextech VI GP owns no securities of the Issuer directly. Charoub, Constantinides and Sgobbo are members of the board of managers of Nextech VI GP and share voting and dispositive power over the shares held by Nextech VI LP, and may be deemed to own beneficially the shares held by Nextech VI LP. The members of the board of managers own no securities of the Issuer directly.

     

    (2)    The percent of class was calculated based on 52,806,137 shares of Common Stock outstanding as of August 5, 2024, as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 7, 2024.

     

    Item 5. Ownership of Five Percent or Less of a Class
      If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following   ¨.
     
    Item 6. Ownership of More than Five Percent on Behalf of Another Person
      Not applicable 
     
    Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person
      Not applicable
     
    Item 8. Identification and Classification of Members of the Group
      Not applicable
     
    Item 9. Notice of Dissolution of Group
      Not applicable
     
    Item 10. Certification
      By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having such purpose or effect.

     

    8

     

     

    Signature

     

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     

    Dated: November 14, 2024  
         
    Nextech VI Oncology SCSp  
         
    By: Nextech VI GP S.à r.l.  
    its General Partner  
         
    By: /s/ Ian Charoub  
      Ian Charoub, Manager  
         
    By: /s/ Costas Constantinides  
      Costas Constantinides, Manager  
         
    Nextech VI GP S.à r.l.  
         
    By: /s/ Ian Charoub  
      Ian Charoub, Manager  
         
    By: /s/ Costas Constantinides  
      Costas Constantinides, Manager  
         
    /s/ Ian Charoub  
    Ian Charoub  
         
    /s/ Costas Constantinides  
    Costas Constantinides  
         
    /s/ Rocco Sgobbo  
    Rocco Sgobbo  

     

      ATTENTION  
         
    Intentional misstatements or omissions of fact constitute Federal Criminal Violations (See 18 U.S.C. 1001).

     

    9

     

     

    Exhibit(s):

     

    A - Joint Filing Statement

     

     

     

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    11/7/24 4:05:00 PM ET
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    Insider Purchases

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    Director Ra Capital Management, L.P. bought $1,664,700 worth of shares (163,287 units at $10.19) (SEC Form 4)

    4 - Tyra Biosciences, Inc. (0001863127) (Issuer)

    6/16/25 8:06:50 PM ET
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    Director Ra Capital Management, L.P. bought $1,904,002 worth of shares (186,850 units at $10.19) (SEC Form 4)

    4 - Tyra Biosciences, Inc. (0001863127) (Issuer)

    6/11/25 7:44:50 PM ET
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    Director Ra Capital Management, L.P. bought $11,751,304 worth of shares (1,211,198 units at $9.70) (SEC Form 4)

    4 - Tyra Biosciences, Inc. (0001863127) (Issuer)

    6/6/25 4:43:19 PM ET
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    SEC Filings

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    SEC Form 8-K filed by Tyra Biosciences Inc.

    8-K - Tyra Biosciences, Inc. (0001863127) (Filer)

    8/21/25 9:43:39 PM ET
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    SEC Form 10-Q filed by Tyra Biosciences Inc.

    10-Q - Tyra Biosciences, Inc. (0001863127) (Filer)

    8/14/25 4:17:47 PM ET
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    Tyra Biosciences Inc. filed SEC Form 8-K: Results of Operations and Financial Condition, Financial Statements and Exhibits

    8-K - Tyra Biosciences, Inc. (0001863127) (Filer)

    8/14/25 4:11:54 PM ET
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    SEC Form 4 filed by Chief Financial Officer Fuhrman Alan

    4 - Tyra Biosciences, Inc. (0001863127) (Issuer)

    8/7/25 4:43:09 PM ET
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    SEC Form 4 filed by Chief Operating Officer Bensen Daniel

    4 - Tyra Biosciences, Inc. (0001863127) (Issuer)

    8/7/25 4:40:24 PM ET
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    Biotechnology: Pharmaceutical Preparations
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    SEC Form 4 filed by Chief Medical Officer Warner Douglas J

    4 - Tyra Biosciences, Inc. (0001863127) (Issuer)

    8/7/25 4:38:02 PM ET
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    Biotechnology: Pharmaceutical Preparations
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