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    Prime Medicine downgraded by Citigroup with a new price target

    5/27/25 9:08:50 AM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $PRME alert in real time by email
    Citigroup downgraded Prime Medicine from Buy to Neutral and set a new price target of $1.50
    Get the next $PRME alert in real time by email

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    Recent Analyst Ratings for
    $PRME

    DatePrice TargetRatingAnalyst
    5/27/2025$1.50Buy → Neutral
    Citigroup
    5/20/2025Overweight → Neutral
    Analyst
    5/20/2025Buy → Neutral
    H.C. Wainwright
    12/10/2024$10.00Mkt Outperform
    JMP Securities
    5/20/2024$10.00Buy
    H.C. Wainwright
    5/16/2024$10.00Neutral → Buy
    Citigroup
    4/22/2024$17.00Buy
    Chardan Capital Markets
    4/8/2024Buy
    TD Cowen
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    $PRME
    Insider Trading

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    SEC Form 4 filed by Chief Technical Officer Lee Ann L.

    4 - Prime Medicine, Inc. (0001894562) (Issuer)

    8/5/25 8:44:42 PM ET
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    SEC Form 4 filed by Director Schenkein David P

    4 - Prime Medicine, Inc. (0001894562) (Issuer)

    8/5/25 8:43:37 PM ET
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    SEC Form 4 filed by Director Nelsen Robert

    4 - Prime Medicine, Inc. (0001894562) (Issuer)

    8/5/25 8:43:27 PM ET
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    Large owner Gv 2021 Gp, L.L.C. bought $4,950,000 worth of shares (1,500,000 units at $3.30) (SEC Form 4)

    4 - Prime Medicine, Inc. (0001894562) (Issuer)

    8/5/25 4:07:52 PM ET
    $PRME
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    Director Nelsen Robert bought $9,999,990 worth of shares (3,030,300 units at $3.30) (SEC Form 4)

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    Large owner Arch Venture Partners Xii, Llc bought $9,999,990 worth of shares (3,030,300 units at $3.30) (SEC Form 4)

    4 - Prime Medicine, Inc. (0001894562) (Issuer)

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    Amendment: SEC Form SCHEDULE 13G/A filed by Prime Medicine Inc.

    SCHEDULE 13G/A - Prime Medicine, Inc. (0001894562) (Subject)

    11/12/25 4:30:21 PM ET
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    SEC Form S-3ASR filed by Prime Medicine Inc.

    S-3ASR - Prime Medicine, Inc. (0001894562) (Filer)

    11/7/25 8:05:14 AM ET
    $PRME
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    SEC Form 10-Q filed by Prime Medicine Inc.

    10-Q - Prime Medicine, Inc. (0001894562) (Filer)

    11/7/25 7:35:53 AM ET
    $PRME
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    Prime Medicine Announces The New England Journal of Medicine Publication of PM359 Clinical Data for the Treatment of Chronic Granulomatous Disease

    CAMBRIDGE, Mass., Dec. 07, 2025 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (NASDAQ:PRME), a biotechnology company committed to delivering a new class of differentiated one-time curative genetic therapies, today announced the publication of Phase 1/2 clinical data with PM359, the Company's investigational autologous hematopoietic stem cell product for p47phox chronic granulomatous disease (CGD) in the New England Journal of Medicine (NEJM). The data will also be presented in a poster session at the 67th American Society of Hematology (ASH) Annual Meeting, December 6-9, 2025 in Orlando, Florida. The publication, titled "Prime Editing for p47-phox Chronic Granulomatous Disease," reports initia

    12/7/25 8:05:00 AM ET
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    Prime Medicine to Present at 8th Annual Evercore Healthcare Conference

    CAMBRIDGE, Mass., Nov. 25, 2025 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (NASDAQ:PRME), a biotechnology company committed to delivering a new class of differentiated one-time curative genetic therapies, today announced that Allan Reine, M.D., Chief Executive Officer of Prime Medicine, will participate in a fireside chat at the 8th Annual Evercore Healthcare Conference on Tuesday, December 2, 2025, at 11:15 a.m. ET in Coral Gables, FL. A live audio webcast of the fireside chat will be available under "Events & Presentations" in the News & Events section of the Company's website at www.primemedicine.com. A replay of the webcast will be available on the Prime Medicine website for 90 days fol

    11/25/25 8:00:00 AM ET
    $PRME
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    Prime Medicine to Present at Jefferies Global Healthcare Conference

    CAMBRIDGE, Mass., Nov. 11, 2025 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (NASDAQ:PRME), a biotechnology company committed to delivering a new class of differentiated one-time curative genetic therapies, today announced that Allan Reine, M.D., Chief Executive Officer of Prime Medicine, will participate in a fireside chat at the Jefferies Global Healthcare Conference on Tuesday, November 18, 2025, at 12:00 noon GMT (7:00 a.m. ET) in London, United Kingdom. A live audio webcast of the fireside chat will be available under "Events & Presentations" in the News & Events section of the Company's website at www.primemedicine.com. A replay of the webcast will be available on the Prime Medicine web

    11/11/25 8:00:00 AM ET
    $PRME
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    Prime Medicine downgraded by Citigroup with a new price target

    Citigroup downgraded Prime Medicine from Buy to Neutral and set a new price target of $1.50

    5/27/25 9:08:50 AM ET
    $PRME
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    Prime Medicine downgraded by Analyst

    Analyst downgraded Prime Medicine from Overweight to Neutral

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    Prime Medicine downgraded by H.C. Wainwright

    H.C. Wainwright downgraded Prime Medicine from Buy to Neutral

    5/20/25 8:09:36 AM ET
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    Prime Medicine Reports Third Quarter 2023 Financial Results and Provides Business Updates

    -- Presented new preclinical research across multiple programs, including proof-of-concept data from in vivo rodent and large animal studies, as well as updates on proprietary delivery systems -- -- Shared detailed safety evaluation of lead Prime Editors across multiple programs; preliminary off-target analyses did not identify off-target editing, supporting potential best-in-class safety profile -- -- Received U.S. FDA Rare Pediatric Drug designation for PM359 for CGD; initiated IND-enabling studies and remain on track to file IND application in 2024 -- -- Further extended intellectual property portfolio; U.S. PTO issued Prime Medicine's third patent, No. 11,795,452 --

    11/3/23 4:01:00 PM ET
    $PRME
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    Prime Medicine Reports Second Quarter 2023 Financial Results and Provides Business Updates

    -- Presented new preclinical data demonstrating ability of Prime Editing to correct causative mutation of CGD and highlighting ability of PASSIGE™ platform to multiplex edit CAR-T cells at ASGCT Annual Meeting -- -- Entered strategic collaboration with Cimeio Therapeutics; multiplexing Cimeio's shielded variants with therapeutic edits may meaningfully expand reach of Prime Editing -- -- Cash, cash equivalents, investments and restricted cash balance of $221.1 million as of June 30, 2023 -- CAMBRIDGE, Mass., Aug. 07, 2023 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (NASDAQ:PRME), a biotechnology company committed to delivering a new class of differentiated one-time curative genetic therapie

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    CORRECTION - Prime Medicine Reports Third Quarter 2025 Financial Results and Provides Business Updates

    -- New preclinical data for PM577 in Wilson's Disease (WD) to be presented at AASLD; on-track to file IND and/or CTA in H1'26, with initial clinical data expected in 2027 --  -- Nominated PM647 as development candidate for Alpha-1 Antitrypsin Deficiency (AATD); on-track to file IND and/or CTA in mid-2026, with initial clinical data expected in 2027 -- -- Strengthened leadership team with the appointment of Matthew Hawryluk, Ph.D., M.B.A. as Chief Business Officer -- -- Company to host virtual KOL event at 8:00am ET on Wednesday, November 12, 2025 to showcase Wilson's Disease Strategy -- CAMBRIDGE, Mass., Nov. 07, 2025 (GLOBE NEWSWIRE) -- In a release issued earlier today by Pr

    11/7/25 10:21:45 AM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
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    Prime Medicine Reports Third Quarter 2025 Financial Results and Provides Business Updates

    -- New preclinical data for PM577 in Wilson's Disease (WD) to be presented at AASLD; on-track to file IND and/or CTA in H1'26, with initial clinical data expected in 2027 --  -- Nominated PM647 as development candidate for Alpha-1 Antitrypsin Deficiency (AATD); on-track to file IND and/or CTA in mid-2026, with initial clinical data expected in 2027 -- -- Strengthened leadership team with the appointment of Matthew Hawryluk, Ph.D., M.B.A. as Chief Business Officer -- -- Company to host virtual KOL event at 8:00am ET on Wednesday, November 12, 2025 to showcase Wilson's Disease Strategy -- CAMBRIDGE, Mass., Nov. 07, 2025 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (NASDAQ:PRME), a biotechno

    11/7/25 7:00:00 AM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
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    Prime Medicine Appoints Matthew Hawryluk, Ph.D., M.B.A. as Chief Business Officer

    CAMBRIDGE, Mass., Nov. 03, 2025 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (NASDAQ:PRME), a biotechnology company committed to delivering a new class of differentiated one-time curative genetic therapies, today announced the appointment of Matthew Hawryluk, Ph.D., M.B.A. as Chief Business Officer (CBO). Dr. Hawryluk will lead Prime's corporate and business development initiatives, corporate strategy, and alliance management functions, advancing the company's efforts to expand the reach of Prime Editing through strategic partnerships and collaborations. "We are thrilled to welcome Matt to our leadership team," said Allan Reine, M.D., Chief Executive Officer of Prime Medicine. "Business devel

    11/3/25 8:01:00 AM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
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    $PRME
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    Amendment: SEC Form SC 13D/A filed by Prime Medicine Inc.

    SC 13D/A - Prime Medicine, Inc. (0001894562) (Subject)

    11/22/24 5:32:53 PM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Amendment: SEC Form SC 13G/A filed by Prime Medicine Inc.

    SC 13G/A - Prime Medicine, Inc. (0001894562) (Subject)

    11/12/24 10:34:15 AM ET
    $PRME
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    SEC Form SC 13G filed by Prime Medicine Inc.

    SC 13G - Prime Medicine, Inc. (0001894562) (Subject)

    10/4/24 4:20:38 PM ET
    $PRME
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