• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
PublishGo to App
    Quantisnow Logo

    © 2026 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlertsPublish with Us
    Company
    AboutQuantisnow PlusContactJobsAI superconnector for talent & startupsNEWLLM Arena
    Legal
    Terms of usePrivacy policyCookie policy

    Prime Medicine Inc. filed SEC Form 8-K: Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Submission of Matters to a Vote of Security Holders, Financial Statements and Exhibits

    6/12/24 4:10:54 PM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $PRME alert in real time by email
    prme-20240612
    0001894562false--12-3100018945622024-06-122024-06-120001894562dei:FormerAddressMember2024-06-122024-06-12

    UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549
    ___________________________________
    FORM 8-K
    ___________________________________
    CURRENT REPORT
    Pursuant to Section 13 or 15(d)
    of the Securities Exchange Act of 1934

    June 12, 2024
    Date of Report (date of earliest event reported)
    ___________________________________
    Prime Medicine, Inc.
    (Exact name of registrant as specified in its charter)
    ___________________________________
    Delaware
    001-41536
    84-3097762
    (State or other jurisdiction of incorporation)
    (Commission File Number)
    (I.R.S. Employer Identification No.)
    60 First Street
    Cambridge, MA
    02141
    (Address of principal executive offices)
    (Zip code)
    (617) 564-0013
    (Registrant's telephone number, including area code)
    21 Erie Street, Cambridge MA 02139
    (Former name or former address, if changed since last report)
    ___________________________________
    Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
    ☐
    Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
    ☐
    Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
    ☐
    Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
    ☐
    Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
    Securities registered pursuant to Section 12(b) of the Act:

    Title of each class
    Trading symbol(s)
    Name of each exchange on which registered
    Common stock, par value $.00001 per sharePRMEThe Nasdaq Global Market
    Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule12b-2 of the Securities Exchange Act of 1934 (§250.12b-2 of this chapter).
    Emerging growth company    ☒
    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐



    Item 5.03 Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year.
    On June 12, 2024, Prime Medicine, Inc. (the “Company”) held its 2024 annual meeting of stockholders (the “Annual Meeting”) in a virtual meeting format via live webcast. As further described in Item 5.07 to this Current Report on Form 8-K, at the Annual Meeting, the Company’s stockholders approved an amendment to the Company’s Third Amended and Restated Certificate of Incorporation (the “Certificate of Amendment”) to limit the liability of certain officers of the Company as permitted by Delaware law, as detailed in the Company’s definitive proxy statement (the “Proxy Statement”) filed on April 29, 2024 with the U.S. Securities and Exchange Commission under Section 14(a) of the Securities Exchange Act of 1934, as amended. The Certificate of Amendment was previously approved by the Company’s Board of Directors, subject to approval by the Company’s stockholders.
    On June 12, 2024, the Company filed the Certificate of Amendment with the Secretary of State of the State of Delaware and the Certificate of Amendment became effective upon filing.
    The foregoing description of the Certificate of Amendment does not purport to be complete and is qualified in its entirety by reference to the full text of the Certificate of Amendment, a copy of which is filed as Exhibit 3.1 to this Current Report on Form 8-K and incorporated herein by reference.
    Item 5.07. Submission of Matters to a Vote of Security Holders.
    The Annual Meeting was held on June 12, 2024. Proxies were solicited pursuant to the Proxy Statement. As of the close of business on April 19, 2024, the record date for the Annual Meeting, the number of shares of the Company’s common stock, $0.00001 par value per share (“Common Stock”), outstanding and entitled to vote at the Annual Meeting was 120,028,813. The number of shares of Common Stock present in person or by remote communication, if applicable, or represented by valid proxy at the Annual Meeting was 107,063,267, thus establishing a quorum for the transaction of business at the Annual Meeting. Shares present virtually during the Annual Meeting were considered shares of Common Stock represented in person at the Annual Meeting. Each share of Common Stock was entitled to one vote with respect to matters submitted to the Company’s stockholders at the Annual Meeting.
    At the Annual Meeting, the Company’s stockholders voted on the following matters, all of which were described in the Proxy Statement: (i) to elect Wendy Chung, M.D., Ph.D., Kaye Foster, Keith Gottesdiener, M.D., and Jeffrey Marrazzo as Class II Directors, each to serve until the Company’s 2027 annual meeting of stockholders, and until his or her respective successor shall have been duly elected and qualified, or until his or her earlier death, resignation or removal (“Proposal 1”), (ii) to approve the Certificate of Amendment to limit the liability of certain of the Company’s officers as permitted by Delaware law (“Proposal 2”), and (iii) to ratify the appointment of PricewaterhouseCoopers LLP as the Company’s independent registered public accounting firm for the fiscal year ending December 31, 2024 (“Proposal 3”). The final voting results are set forth below.
    Proposal 1 – Each of the following nominees was elected as a Class II Director to serve until the Company’s 2027 annual meeting of stockholders, and until his or her respective successor shall have been duly elected and qualified, or until his or her earlier death, resignation or removal, based on the following votes:
    Class II Director NomineeForWithheldBroker Non-Votes
    Wendy Chung, M.D., Ph.D.84,178,13215,425,6157,459,520
    Kaye Foster99,386,538217,2097,459,520
    Keith Gottesdiener, M.D.99,397,598206,1497,459,520
    Jeffrey Marrazzo98,518,4091,085,3387,459,520
    Proposal 2 – The Certificate of Amendment to limit the liability of certain of the Company’s officers as permitted by Delaware law was approved, based on the following votes:
    ForAgainstAbstentionsBroker Non-Votes
    91,545,1467,857,228201,3737,459,520



    Proposal 3 – The appointment of PricewaterhouseCoopers LLP as the Company’s independent registered public accounting firm for the fiscal year ending December 31, 2024 was ratified, based on the following votes:
    ForAgainstAbstentions
    106,909,1523,764150,351
    Item 9.01 Financial Statements and Exhibits.
    (d) Exhibits
    Exhibit
    Number
    Description
    3.1
    Certificate of Amendment to the Third Amended and Restated Certificate of Incorporation of Prime Medicine, Inc.
    104
    Cover Page Interactive Data File (embedded within the Inline XBRL document)



    SIGNATURE

    Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

    Date: June 12, 2024
    Prime Medicine, Inc.
    By:
    /s/ Keith Gottesdiener
    Name:
    Keith Gottesdiener, M.D.
    Title:
    President and Chief Executive Officer

    Get the next $PRME alert in real time by email

    Crush Q1 2026 with the Best AI Superconnector

    Stay ahead of the competition with Standout.work - your AI-powered talent-to-startup matching platform.

    AI-Powered Inbox
    Context-aware email replies
    Strategic Decision Support
    Get Started with Standout.work

    Recent Analyst Ratings for
    $PRME

    DatePrice TargetRatingAnalyst
    3/12/2026$11.00Outperform
    Oppenheimer
    5/27/2025$1.50Buy → Neutral
    Citigroup
    5/20/2025Overweight → Neutral
    Analyst
    5/20/2025Buy → Neutral
    H.C. Wainwright
    12/10/2024$10.00Mkt Outperform
    JMP Securities
    5/20/2024$10.00Buy
    H.C. Wainwright
    5/16/2024$10.00Neutral → Buy
    Citigroup
    4/22/2024$17.00Buy
    Chardan Capital Markets
    More analyst ratings

    $PRME
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    View All

    Oppenheimer initiated coverage on Prime Medicine with a new price target

    Oppenheimer initiated coverage of Prime Medicine with a rating of Outperform and set a new price target of $11.00

    3/12/26 8:54:37 AM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Prime Medicine downgraded by Citigroup with a new price target

    Citigroup downgraded Prime Medicine from Buy to Neutral and set a new price target of $1.50

    5/27/25 9:08:50 AM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Prime Medicine downgraded by Analyst

    Analyst downgraded Prime Medicine from Overweight to Neutral

    5/20/25 8:09:46 AM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $PRME
    Press Releases

    Fastest customizable press release news feed in the world

    View All

    Prime Medicine Appoints Svetlana Makhni as Chief Financial Officer

    CAMBRIDGE, Mass., April 16, 2026 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (NASDAQ:PRME), a biotechnology company committed to delivering a new class of differentiated one-time curative genetic therapies, today announced the appointment of Svetlana Makhni as Chief Financial Officer (CFO). Ms. Makhni will oversee Prime Medicine's financial operations and strategy, including investor relations, financial planning and analysis, and corporate development. "We are delighted to welcome Svetlana to Prime Medicine," said Allan Reine, M.D., Chief Executive Officer of Prime Medicine. "Svetlana brings proven leadership at clinical-stage biotechnology companies, as well as deep capital markets experti

    4/16/26 8:00:00 AM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Prime Medicine Reports Full Year 2025 Financial Results and Provides Business Updates

    -- On track to file IND and/or CTA for Wilson Disease and AATD programs in 1H 2026 and mid-2026, respectively; initial clinical data for both expected in 2027 -- -- Ongoing engagement with FDA for PM359 in CGD; plan to submit BLA following final alignment -- -- Prime Medicine reported cash, cash equivalents, investments, and restricted cash of $191M providing cash runway into 2027 -- CAMBRIDGE, Mass., March 03, 2026 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (NASDAQ:PRME), a biotechnology company committed to delivering a new class of differentiated one-time curative genetic therapies, today reported financial results for the full year ended December 31, 2025 and provided a business updat

    3/3/26 8:00:00 AM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Prime Medicine to Participate in Upcoming Investor Conferences

    CAMBRIDGE, Mass., Feb. 25, 2026 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (NASDAQ:PRME), a biotechnology company committed to delivering a new class of differentiated one-time curative genetic therapies, today announced that company management will participate in three upcoming conferences: TD Cowen 46th Annual Health Care Conference: Fireside chat on Wednesday, March 4, 2026, at 1:10 p.m. ET in Boston, MA.2026 Jefferies Biotech on the Beach Summit: Company management will host 1x1 meetings on Tuesday, March 10, 2026, in Miami Beach, FL.The Citizens Life Sciences Conference: Fireside chat on Wednesday, March 11, 2026, at 2:15 p.m. ET in Miami Beach, FL. Live audio webcasts of the fireside

    2/25/26 8:00:00 AM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $PRME
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    View All

    $PRME
    SEC Filings

    View All

    $PRME
    Insider Purchases

    Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

    View All

    SEC Form 4 filed by Makhni Svetlana Ni

    4 - Prime Medicine, Inc. (0001894562) (Issuer)

    4/17/26 8:26:48 PM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form 3 filed by new insider Makhni Svetlana Ni

    3 - Prime Medicine, Inc. (0001894562) (Issuer)

    4/17/26 8:25:03 PM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form 4 filed by Chief Executive Officer Reine Allan

    4 - Prime Medicine, Inc. (0001894562) (Issuer)

    2/27/26 4:52:39 PM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Prime Medicine Inc. filed SEC Form 8-K: Leadership Update, Financial Statements and Exhibits

    8-K - Prime Medicine, Inc. (0001894562) (Filer)

    4/16/26 8:15:51 AM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form EFFECT filed by Prime Medicine Inc.

    EFFECT - Prime Medicine, Inc. (0001894562) (Filer)

    3/5/26 12:15:13 AM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form S-8 filed by Prime Medicine Inc.

    S-8 - Prime Medicine, Inc. (0001894562) (Filer)

    3/3/26 8:41:10 AM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Large owner Gv 2021 Gp, L.L.C. bought $4,950,000 worth of shares (1,500,000 units at $3.30) (SEC Form 4)

    4 - Prime Medicine, Inc. (0001894562) (Issuer)

    8/5/25 4:07:52 PM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Director Nelsen Robert bought $9,999,990 worth of shares (3,030,300 units at $3.30) (SEC Form 4)

    4 - Prime Medicine, Inc. (0001894562) (Issuer)

    8/1/25 7:19:58 PM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Large owner Arch Venture Partners Xii, Llc bought $9,999,990 worth of shares (3,030,300 units at $3.30) (SEC Form 4)

    4 - Prime Medicine, Inc. (0001894562) (Issuer)

    8/1/25 7:19:33 PM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $PRME
    Leadership Updates

    Live Leadership Updates

    View All

    Prime Medicine Appoints Svetlana Makhni as Chief Financial Officer

    CAMBRIDGE, Mass., April 16, 2026 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (NASDAQ:PRME), a biotechnology company committed to delivering a new class of differentiated one-time curative genetic therapies, today announced the appointment of Svetlana Makhni as Chief Financial Officer (CFO). Ms. Makhni will oversee Prime Medicine's financial operations and strategy, including investor relations, financial planning and analysis, and corporate development. "We are delighted to welcome Svetlana to Prime Medicine," said Allan Reine, M.D., Chief Executive Officer of Prime Medicine. "Svetlana brings proven leadership at clinical-stage biotechnology companies, as well as deep capital markets experti

    4/16/26 8:00:00 AM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    CORRECTION - Prime Medicine Reports Third Quarter 2025 Financial Results and Provides Business Updates

    -- New preclinical data for PM577 in Wilson's Disease (WD) to be presented at AASLD; on-track to file IND and/or CTA in H1'26, with initial clinical data expected in 2027 --  -- Nominated PM647 as development candidate for Alpha-1 Antitrypsin Deficiency (AATD); on-track to file IND and/or CTA in mid-2026, with initial clinical data expected in 2027 -- -- Strengthened leadership team with the appointment of Matthew Hawryluk, Ph.D., M.B.A. as Chief Business Officer -- -- Company to host virtual KOL event at 8:00am ET on Wednesday, November 12, 2025 to showcase Wilson's Disease Strategy -- CAMBRIDGE, Mass., Nov. 07, 2025 (GLOBE NEWSWIRE) -- In a release issued earlier today by Pr

    11/7/25 10:21:45 AM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Prime Medicine Reports Third Quarter 2025 Financial Results and Provides Business Updates

    -- New preclinical data for PM577 in Wilson's Disease (WD) to be presented at AASLD; on-track to file IND and/or CTA in H1'26, with initial clinical data expected in 2027 --  -- Nominated PM647 as development candidate for Alpha-1 Antitrypsin Deficiency (AATD); on-track to file IND and/or CTA in mid-2026, with initial clinical data expected in 2027 -- -- Strengthened leadership team with the appointment of Matthew Hawryluk, Ph.D., M.B.A. as Chief Business Officer -- -- Company to host virtual KOL event at 8:00am ET on Wednesday, November 12, 2025 to showcase Wilson's Disease Strategy -- CAMBRIDGE, Mass., Nov. 07, 2025 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (NASDAQ:PRME), a biotechno

    11/7/25 7:00:00 AM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $PRME
    Financials

    Live finance-specific insights

    View All

    Prime Medicine Reports Third Quarter 2023 Financial Results and Provides Business Updates

    -- Presented new preclinical research across multiple programs, including proof-of-concept data from in vivo rodent and large animal studies, as well as updates on proprietary delivery systems -- -- Shared detailed safety evaluation of lead Prime Editors across multiple programs; preliminary off-target analyses did not identify off-target editing, supporting potential best-in-class safety profile -- -- Received U.S. FDA Rare Pediatric Drug designation for PM359 for CGD; initiated IND-enabling studies and remain on track to file IND application in 2024 -- -- Further extended intellectual property portfolio; U.S. PTO issued Prime Medicine's third patent, No. 11,795,452 --

    11/3/23 4:01:00 PM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Prime Medicine Reports Second Quarter 2023 Financial Results and Provides Business Updates

    -- Presented new preclinical data demonstrating ability of Prime Editing to correct causative mutation of CGD and highlighting ability of PASSIGE™ platform to multiplex edit CAR-T cells at ASGCT Annual Meeting -- -- Entered strategic collaboration with Cimeio Therapeutics; multiplexing Cimeio's shielded variants with therapeutic edits may meaningfully expand reach of Prime Editing -- -- Cash, cash equivalents, investments and restricted cash balance of $221.1 million as of June 30, 2023 -- CAMBRIDGE, Mass., Aug. 07, 2023 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (NASDAQ:PRME), a biotechnology company committed to delivering a new class of differentiated one-time curative genetic therapie

    8/7/23 4:01:00 PM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $PRME
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    View All

    Amendment: SEC Form SC 13D/A filed by Prime Medicine Inc.

    SC 13D/A - Prime Medicine, Inc. (0001894562) (Subject)

    11/22/24 5:32:53 PM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Amendment: SEC Form SC 13G/A filed by Prime Medicine Inc.

    SC 13G/A - Prime Medicine, Inc. (0001894562) (Subject)

    11/12/24 10:34:15 AM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form SC 13G filed by Prime Medicine Inc.

    SC 13G - Prime Medicine, Inc. (0001894562) (Subject)

    10/4/24 4:20:38 PM ET
    $PRME
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care